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Volumn 6, Issue 4, 2006, Pages 364-368

Inhibition of poly(ADP-ribose) polymerase in cancer

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXY 2 METHYL 4(3H) QUINAZOLINONE; AG 014699; ALKYLATING AGENT; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; BENZIMIDAZOLE 4 CARBOXAMIDE; BENZIMIDAZOLE DERIVATIVE; BLEOMYCIN; CAMPTOTHECIN; CARBAZOLE DERIVATIVE; CEP 6800; CISPLATIN; CYTOTOXIC AGENT; DEMETHYL SULFATE; DNA; ETOPOSIDE; GEMCITABINE; GPI 15427; INO 1001; IRINOTECAN; KU 00559436; NEW DRUG; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NOLATREXED; NU 1085; TEMOZOLOMIDE; TOPOTECAN; UNCLASSIFIED DRUG;

EID: 33745876586     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2006.02.004     Document Type: Review
Times cited : (104)

References (43)
  • 1
    • 27944445390 scopus 로고    scopus 로고
    • The emerging role of DNA repair proteins as predictive, prognostic and therapeutic targets in cancer
    • Recent comprehensive review on DNA repair proteins and early drugs in clinic.
    • Madhusudan S., and Middleton M.R. The emerging role of DNA repair proteins as predictive, prognostic and therapeutic targets in cancer. Cancer Treat Rev 31 (2005) 603-617. Recent comprehensive review on DNA repair proteins and early drugs in clinic.
    • (2005) Cancer Treat Rev , vol.31 , pp. 603-617
    • Madhusudan, S.1    Middleton, M.R.2
  • 2
    • 0036270993 scopus 로고    scopus 로고
    • DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis
    • Bernstein C., Bernstein H., Payne C.M., and Garewal H. DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis. Mutat Res 511 (2002) 145-178
    • (2002) Mutat Res , vol.511 , pp. 145-178
    • Bernstein, C.1    Bernstein, H.2    Payne, C.M.3    Garewal, H.4
  • 4
    • 0035902108 scopus 로고    scopus 로고
    • Genone maintenance mechanisms for preventing cancer
    • Hoeijmakers J.H. Genone maintenance mechanisms for preventing cancer. Nature 411 (2001) 366-374
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 5
    • 0025902273 scopus 로고
    • Endogenous mutagens and the causes of aging and cancer
    • Ames B.N., and Gold L.S. Endogenous mutagens and the causes of aging and cancer. Mutat Res 250 (1991) 3-16
    • (1991) Mutat Res , vol.250 , pp. 3-16
    • Ames, B.N.1    Gold, L.S.2
  • 6
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B., and Kinzler K.W. Cancer genes and the pathways they control. Nat Med 10 (2004) 789-799
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 7
    • 0031906084 scopus 로고    scopus 로고
    • The role of DNA mismatch repair in drug resistance
    • Fink D., Aebi S., and Howell S. The role of DNA mismatch repair in drug resistance. Clin Cancer Res 4 (1998) 1-6
    • (1998) Clin Cancer Res , vol.4 , pp. 1-6
    • Fink, D.1    Aebi, S.2    Howell, S.3
  • 8
    • 27744495771 scopus 로고    scopus 로고
    • Epigenetic silencing of the MGMT gene in cancer
    • Soejima H., Zhao W., and Mukai T. Epigenetic silencing of the MGMT gene in cancer. Biochem Cell Biol 83 (2005) 429-437
    • (2005) Biochem Cell Biol , vol.83 , pp. 429-437
    • Soejima, H.1    Zhao, W.2    Mukai, T.3
  • 9
    • 14544268189 scopus 로고    scopus 로고
    • DNA repair defects in stem cell function and aging
    • Park Y., and Gerson S.L. DNA repair defects in stem cell function and aging. Annu Rev Med 56 (2005) 495-508
    • (2005) Annu Rev Med , vol.56 , pp. 495-508
    • Park, Y.1    Gerson, S.L.2
  • 10
    • 0002160618 scopus 로고
    • Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid sythesizing nuclear enzyme
    • Chambon P., Weil J., and Mandel P. Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid sythesizing nuclear enzyme. Biochem Biophys Res Commun 11 (1963) 39
    • (1963) Biochem Biophys Res Commun , vol.11 , pp. 39
    • Chambon, P.1    Weil, J.2    Mandel, P.3
  • 11
    • 0000102949 scopus 로고
    • Poly(ADP-ribose) polymerase: a molecular nick-sensor
    • de Murcia G., and Menissier de Murcia J. Poly(ADP-ribose) polymerase: a molecular nick-sensor. Trends Biochem Sci 19 (1994) 172-176
    • (1994) Trends Biochem Sci , vol.19 , pp. 172-176
    • de Murcia, G.1    Menissier de Murcia, J.2
  • 12
    • 0035425899 scopus 로고    scopus 로고
    • Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism
    • Davidovic L., Vodenicharov M., Affar E.B., and Poirier G.G. Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism. Exp Cell Res 268 (2001) 7-13
    • (2001) Exp Cell Res , vol.268 , pp. 7-13
    • Davidovic, L.1    Vodenicharov, M.2    Affar, E.B.3    Poirier, G.G.4
  • 13
    • 31044446360 scopus 로고    scopus 로고
    • PARP inhibitors for cancer therapy
    • Excellent recent review of preclinical work leading to early clinical trials of PARP inhibitors.
    • Curtin N.J. PARP inhibitors for cancer therapy. Expert Rev Mol Med 7 (2005) 1-20. Excellent recent review of preclinical work leading to early clinical trials of PARP inhibitors.
    • (2005) Expert Rev Mol Med , vol.7 , pp. 1-20
    • Curtin, N.J.1
  • 14
    • 0018990986 scopus 로고
    • Novel inhibitors of poly(ADP-ribose) synthetase
    • Purnell M.R., and Whish W.J.D. Novel inhibitors of poly(ADP-ribose) synthetase. Biochem J 185 (1980) 775-777
    • (1980) Biochem J , vol.185 , pp. 775-777
    • Purnell, M.R.1    Whish, W.J.D.2
  • 16
    • 0037239590 scopus 로고    scopus 로고
    • Poly(ADP-ribose) ploymerase inhibitors
    • Southan G., and Szabo C. Poly(ADP-ribose) ploymerase inhibitors. Curr Med Chem 10 (2003) 321-340
    • (2003) Curr Med Chem , vol.10 , pp. 321-340
    • Southan, G.1    Szabo, C.2
  • 18
    • 0031762817 scopus 로고    scopus 로고
    • Potentiation of anti-cancer agent cytotoxicity by the potent poly(ADP-ribose) polymerase inhibitors NU1025 and NU1064
    • Bowman K.J., White A., Golding B.T., Griffin R.J., and Curtin N.J. Potentiation of anti-cancer agent cytotoxicity by the potent poly(ADP-ribose) polymerase inhibitors NU1025 and NU1064. Br J Cancer 78 (1998) 1269-1277
    • (1998) Br J Cancer , vol.78 , pp. 1269-1277
    • Bowman, K.J.1    White, A.2    Golding, B.T.3    Griffin, R.J.4    Curtin, N.J.5
  • 19
    • 0028826231 scopus 로고
    • Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors
    • Boulton S., Pemberton L.C., Porteous J.K., Curtin N.J., Griffin R.J., Golding B.T., and Durkacz B.W. Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors. Br J Cancer 72 (1995) 849-856
    • (1995) Br J Cancer , vol.72 , pp. 849-856
    • Boulton, S.1    Pemberton, L.C.2    Porteous, J.K.3    Curtin, N.J.4    Griffin, R.J.5    Golding, B.T.6    Durkacz, B.W.7
  • 20
    • 0035137364 scopus 로고    scopus 로고
    • Differential effects of the poly(ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro
    • Bowman K.J., Newell D.R., Calvert A.H., and Curtin N.J. Differential effects of the poly(ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro. Br J Cancer 84 (2001) 106-112
    • (2001) Br J Cancer , vol.84 , pp. 106-112
    • Bowman, K.J.1    Newell, D.R.2    Calvert, A.H.3    Curtin, N.J.4
  • 21
    • 0033941729 scopus 로고    scopus 로고
    • Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines
    • Delaney C.A., Wang L.Z., Kyle S., White A.W., Calvert A.H., Curtin N.J., Durkacz B.W., Hostomsky Z., and Newell D.R. Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines. Clin Cancer Res 6 (2000) 2860-2867
    • (2000) Clin Cancer Res , vol.6 , pp. 2860-2867
    • Delaney, C.A.1    Wang, L.Z.2    Kyle, S.3    White, A.W.4    Calvert, A.H.5    Curtin, N.J.6    Durkacz, B.W.7    Hostomsky, Z.8    Newell, D.R.9
  • 23
    • 10744233684 scopus 로고    scopus 로고
    • Systemic administration of GPI, 15427 a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma
    • Tentori L., Leonetti C., Scarsella M., D'Amati G., Vergati M., Portarena I., Xu W., Kalish V., Zupi G., Zhang J., and Graziani G. Systemic administration of GPI, 15427 a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma. Clin Cancer Res 9 (2003) 5370-5379
    • (2003) Clin Cancer Res , vol.9 , pp. 5370-5379
    • Tentori, L.1    Leonetti, C.2    Scarsella, M.3    D'Amati, G.4    Vergati, M.5    Portarena, I.6    Xu, W.7    Kalish, V.8    Zupi, G.9    Zhang, J.10    Graziani, G.11
  • 26
    • 10744226451 scopus 로고    scopus 로고
    • Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361
    • Preclinical data detailing the early work with the class of PARP inhibitors first taken into cancer therapy trials.
    • Calabrese C.R., Almassy R., Barton S., Batey M.A., Calvert A.H., Canan-Koch S., Durkacz B.W., Hostomsky Z., Kumpf R.A., Kyle S., et al. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. J Natl Cancer Inst 96 (2004) 56-67. Preclinical data detailing the early work with the class of PARP inhibitors first taken into cancer therapy trials.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 56-67
    • Calabrese, C.R.1    Almassy, R.2    Barton, S.3    Batey, M.A.4    Calvert, A.H.5    Canan-Koch, S.6    Durkacz, B.W.7    Hostomsky, Z.8    Kumpf, R.A.9    Kyle, S.10
  • 27
    • 19444375973 scopus 로고    scopus 로고
    • Chemopotentiation by PARP inhibitors in cancer therapy
    • Recent review of all preclinical data demonstrating chemopotentiation with a range of cytotoxics.
    • Tentori L., and Graziani G. Chemopotentiation by PARP inhibitors in cancer therapy. Pharmacol Res 52 (2005) 25-33. Recent review of all preclinical data demonstrating chemopotentiation with a range of cytotoxics.
    • (2005) Pharmacol Res , vol.52 , pp. 25-33
    • Tentori, L.1    Graziani, G.2
  • 28
    • 0037085761 scopus 로고    scopus 로고
    • Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site
    • Tentori L., Leonetti C., Scarsella M., d'Amati G., Portarena I., Zupi G., Bonmassar E., and Graziani G. Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site. Blood 99 (2002) 2241-2244
    • (2002) Blood , vol.99 , pp. 2241-2244
    • Tentori, L.1    Leonetti, C.2    Scarsella, M.3    d'Amati, G.4    Portarena, I.5    Zupi, G.6    Bonmassar, E.7    Graziani, G.8
  • 29
    • 0032587580 scopus 로고    scopus 로고
    • Treatment with temozolomide and poly(ADP-ribose) polymerase inhibitors induces early apoptosis and increases base excision repair gene transcripts in leukemic cells resistant to triazene compounds
    • Tentori L., Turriziani M., Franco D., Serafino A., Levati L., Roy R., Bonmassar E., and Graziani G. Treatment with temozolomide and poly(ADP-ribose) polymerase inhibitors induces early apoptosis and increases base excision repair gene transcripts in leukemic cells resistant to triazene compounds. Leukemia 13 (1999) 901-909
    • (1999) Leukemia , vol.13 , pp. 901-909
    • Tentori, L.1    Turriziani, M.2    Franco, D.3    Serafino, A.4    Levati, L.5    Roy, R.6    Bonmassar, E.7    Graziani, G.8
  • 30
    • 0034743378 scopus 로고    scopus 로고
    • Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components
    • Tentori L., Portarena I., Vernole P., De Fabritiis P., Madaio R., Balduzzi A., Roy R., Bonmassar E., and Graziani G. Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components. Cancer Chemother Pharmacol 47 (2001) 361-369
    • (2001) Cancer Chemother Pharmacol , vol.47 , pp. 361-369
    • Tentori, L.1    Portarena, I.2    Vernole, P.3    De Fabritiis, P.4    Madaio, R.5    Balduzzi, A.6    Roy, R.7    Bonmassar, E.8    Graziani, G.9
  • 31
    • 33745911849 scopus 로고    scopus 로고
    • Plummer R, Middleton M, Wilson R, Jones C, Evans J, Robson L, Steinfeldt H, Kaufman R, Reich S, Calvert AH. First in human phase I trial of the PARP inhibitor AG-014699 with temozolomide (TMZ) in patients (pts) with advanced solid tumors. ASCO Meeting Abstracts 2005:3065.
  • 32
    • 4143130089 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation inhibitors: promising drug candidates for a wide variety of pathophysiologic conditions
    • Beneke S., Diefenbach J., and Burkle A. Poly(ADP-ribosyl)ation inhibitors: promising drug candidates for a wide variety of pathophysiologic conditions. Int J Cancer 111 (2004) 813-818
    • (2004) Int J Cancer , vol.111 , pp. 813-818
    • Beneke, S.1    Diefenbach, J.2    Burkle, A.3
  • 33
    • 0141619287 scopus 로고    scopus 로고
    • Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1
    • Veuger S.J., Curtin N.J., Richardson C.J., Smith G.C., and Durkacz B.W. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1. Cancer Res 63 (2003) 6008-6015
    • (2003) Cancer Res , vol.63 , pp. 6008-6015
    • Veuger, S.J.1    Curtin, N.J.2    Richardson, C.J.3    Smith, G.C.4    Durkacz, B.W.5
  • 34
    • 10944251591 scopus 로고    scopus 로고
    • Repair and genetic consequences of endogenous DNA base damage in mammalian cells
    • Barnes D.E., and Lindahl T. Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu Rev Genet 38 (2004) 445-476
    • (2004) Annu Rev Genet , vol.38 , pp. 445-476
    • Barnes, D.E.1    Lindahl, T.2
  • 38
    • 23644445483 scopus 로고    scopus 로고
    • Oh what a tangled web it weaves: BRCA1 and DNA decatenation
    • Ashworth A. Oh what a tangled web it weaves: BRCA1 and DNA decatenation. Cancer Cell 8 (2005) 95-97
    • (2005) Cancer Cell , vol.8 , pp. 95-97
    • Ashworth, A.1
  • 40
    • 21644467334 scopus 로고    scopus 로고
    • Pharmacological inhibition of poly(ADP-ribose) polymerase in cardiovascular disorders: future directions
    • Recent review of cardiovascular indications by a leading researcher in field.
    • Szabo C. Pharmacological inhibition of poly(ADP-ribose) polymerase in cardiovascular disorders: future directions. Curr Vasc Pharmacol 3 (2005) 301-303. Recent review of cardiovascular indications by a leading researcher in field.
    • (2005) Curr Vasc Pharmacol , vol.3 , pp. 301-303
    • Szabo, C.1
  • 41
    • 19444363980 scopus 로고    scopus 로고
    • Shock inflammation and PARP
    • Cuzzocrea S: Shock. inflammation and PARP. Pharmacol Res 52 (2005) 72-82
    • (2005) Pharmacol Res , vol.52 , pp. 72-82
    • Cuzzocrea, S.1
  • 42
    • 19444362951 scopus 로고    scopus 로고
    • Clinical perspectives of PARP inhibitors
    • Graziani G., and Szabo C. Clinical perspectives of PARP inhibitors. Pharmacol Res 52 (2005) 109-118
    • (2005) Pharmacol Res , vol.52 , pp. 109-118
    • Graziani, G.1    Szabo, C.2
  • 43
    • 18944390248 scopus 로고    scopus 로고
    • Poly(ADP-Ribose)polymerase and the therapeautic effects of its inhibitors
    • Jagtap P., and Szabo C. Poly(ADP-Ribose)polymerase and the therapeautic effects of its inhibitors. Nat Rev Drug Discov 4 (2005) 421-440
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 421-440
    • Jagtap, P.1    Szabo, C.2


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