Potentiation of anti-cancer agent cytotoxicity by the potent poly(ADP-ribose) polymerase inhibitors NU1025 and NU1064

British Journal of Cancer

Volumn 78, Issue 10, 1998, Pages 1269-1277

  Bowman, J K ^a   White, A ^a   Golding, B T ^a   Griffin, R J ^a   Curtin, N J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Cytotoxicity; DNA repair; DNA alkylating agents; PARP inhibitors; Poly(ADP ribose) polymerase; irradiation

Indexed keywords

8 HYDROXY 2 METHYL 4(3H) QUINAZOLINONE; ANTINEOPLASTIC AGENT; BENZIMIDAZOLE DERIVATIVE; BLEOMYCIN; ENZYME INHIBITOR; GEMCITABINE; IMIDAZOLE DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NOLATREXED; NU 1064; QUINAZOLINONE DERIVATIVE; TEMOZOLOMIDE; THYMIDYLATE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA REPAIR; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; DRUG POTENTIATION; GAMMA RADIATION; LEUKEMIA L 1210; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0031762817     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.670     Document Type: Article

References (35)