Identification of potent nontoxic poly(ADP-ribose) polymerase-1 inhibitors: Chemopotentiation and pharmacological studies

Clinical Cancer Research

Volumn 9, Issue 7, 2003, Pages 2711-2718

  Calabrese, Christopher R ^a   Batey, Michael A ^a   Thomas, Huw D ^a   Durkacz, Barbara W ^a   Wang, Lan Zhen ^a   Kyle, Suzanne ^a   Skalitzky, Donald ^b   Li, Janke ^b   Zhang, Catherine ^b   Boritzki, Theodore ^b   Maegley, Karen ^b   Calvert, Alan H ^a   Hostomsky, Zdenek ^b   Newell, David R ^a   Curtin, Nicola J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; BENZIMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; LACTAM DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PD 128763; QUINAZOLINE DERIVATIVE; TEMOZOLOMIDE; TOPOTECAN; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; COLON CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; DRUG SCREENING; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT; WILD TYPE;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL DIVISION; CELL LINE, TUMOR; DACARBAZINE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; INDOLES; KINETICS; MODELS, CHEMICAL; POLY(ADP-RIBOSE) POLYMERASES; TEMPERATURE; TIME FACTORS; TISSUE DISTRIBUTION; TOPOTECAN;

EID: 12444276597     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

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