Possible functions of p94 in connectin-mediated signaling pathways in skeletal muscle cells

Journal of Muscle Research and Cell Motility

Volumn 26, Issue 6-8, 2005, Pages 409-417

  Ojima, Koichi ^a,b   Ono, Yasuko ^a   Hata, Shoji ^a   Koyama, Suguru ^a,c   Doi, Naoko ^a,b   Sorimachi, Hiroyuki ^a,b  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ; ANKYRIN; BINDING PROTEIN; CALCIUM ION; CALPAIN; CALPAIN 3; CONNECTIN; MUSCLE ANKYRIN REPEAT PROTEIN; MUSCLE PROTEIN; MUSCLE RING FINGER PROTEIN; PROTEINASE; TITIN CAPPING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; BINDING SITE; CALCIUM CELL LEVEL; CELL FUNCTION; COMPLEX FORMATION; CONFERENCE PAPER; ELASTICITY; GENE; GENE EXPRESSION; GENE MUTATION; GENETICS; IMMUNOHISTOCHEMISTRY; LIMB GIRDLE MUSCULAR DYSTROPHY; MOUSE; MUSCLE CONTRACTILITY; MUSCLE FIBRIL; MUSCLE FUNCTION; NONHUMAN; P94 GENE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; SARCOMERE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STRESS; TWO HYBRID SYSTEM; YEAST;

ACTININ; ANIMALS; CALPAIN; CELLS, CULTURED; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MUSCLE FIBERS; MUSCLE FIBERS, SKELETAL; MUSCLE PROTEINS; PROTEIN KINASES; SARCOMERES; SIGNAL TRANSDUCTION;

EID: 33745712380     PISSN: 01424319     EISSN: 15732657     Source Type: Journal    
DOI: 10.1007/s10974-005-9023-8     Document Type: Conference Paper

References (64)

1. Baghdiguian S, Martin M, Richard I, Pons F, Astier C, Bourg N, Hay RT, Chemaly R, Halaby G, Loiselet J, Anderson LVB, Munain ALd , Fardeau M, Mangeat P, Beckmann JS and Lefranc G (1999) Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IB/NF-B pathway in limb-girdle muscular dystrophy type 2A. Nat Med 5: 503-511.
2. Baumeister A, Arber S and Caroni P (1997) Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis. J Cell Biol 139: 1231-1242.
3. Bischoff R (1986) Proliferation of muscle satellite cells on intact myofibers in culture. Dev Biol 115: 129-139.
4. Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuela DM, DeChiara TM, Stitt TN, Yancopoulos GD and Glass DJ (2001) Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294: 1704-1708.
5. Centner T, Yano J, Kimura E, McElhinny AS, Pelin K, Witt CC, Bang M-L, Trombitas K, Granzier H, Gregorio CC, Sorimachi H and Labeit S (2001) Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain. J Mol Biol 306: 717-726.
6. 2+-dependent proteinases (calpains) and muscle cell differentiation. Biochim Biophys Acta 1223: 170-178.
7. Dai K-S and Liew C-C (2001) A novel human striated muscle RING zinc finger protein, SMRZ, interacts with SMT3b via its RING domain. J Biol Chem 276: 23992-23999.
8. Evarsti J (2003) Costameres: the Achilles' heel of Herculean muscle. J Biol Chem 278: 13591-13594.
9. Franco SJ, Rodgers MA, Perrin BJ, Han J, Bennin DA, Critchley DR and Huttenlocher A (2004) Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol 6: 977-983.
10. Furukawa T, Ono Y, Tsuchiya H, Katayama Y, Bang M-L, Labeit D, Labeit S, Inagaki N and Gregorio CC (2001) Specific interaction of the potassium channel-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system. J Mol Biol 313: 775-784.
11. Garvey SM, Rajan C, Lerner AP, Frankel WN and Cox GA (2002) The muscular dystrophy with myositis (mdm) mouse mutation disrupts a skeletal muscle-specific domain of titin. Genomics 79: 146-149.
12. Glading A, Lauffenburger DA and Wells A (2002) Cutting to the chase: calpain proteases in cell motility. Trends Cell Biol 12: 46-54.
13. Goll DE, Thompson VF, Li H, Wei W and Cong J (2003) The calpain system. Physiol Rev 83: 731-801.
14. Gotthardt M, Hammer RE, Hubner N, Monti J, Witt CC, McNabb M, Richardson JA, Granzier H and Labeit S (2003) Conditional expression of mutant titins results in cardiomyopathy with altered sarcomere structure. J Biol Chem 278: 6059-6065.
15. Granzier HL and Labeit S (2004) The giant protein titin: a major player in myocardial mechanics, signaling and disease. Circ Res 94: 284-295.
16. Gregorio CC, Granzier H, Sorimachi H and Labeit S (1999) Muscle assembly: a titanic achievement?. Curr Opin Cell Biol 11: 18-25.
17. Gregorio CC, Trombitás K, Centner T, Kolmerer B, Stier G, Kunke K, Suzuki K, Obermayr F, Herrmann B, Granzier H, Sorimachi H and Labeit S (1998) The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity. J Cell Biol 143: 1013-1027.
18. Hackman P, Vihola A, Haravuori H, Marchand S, Sarparanta J, De Seze J, Labeit S, Witt C, Peltonen L, Richard I and Udd B (2002) Tibial muscular dystrophy is a titinopathy caused by mutations in TTN, the gene encoding the giant skeletal-muscle protein titin. Am J Hum Genet 71: 492-500.
19. Hata S, Sorimachi H, Nakagawa K, Maeda T, Abe K and Suzuki K (2001) Both the conserved and the unique gene structure of stomach-specific calpains reveal processes of calpain gene evolution. J Mol Evol 53: 191-203.
20. Hauser MA, Korrigan SK, Salmikangas P, Torian UM, Viles KD, Dancel R, Tim RW, Taivainen A, Bartoloni L, Gilchrist JM, Stajich JM, Gaskell PC, Gilbert JR, Vance JM, Pericak-Vance MA, Carpen O, Westbrook CA and Speer MC (2000) Myotilin is mutated in limb girdle muscular dystrophy 1A. Hum Mol Genet 9: 2141-2147.
21. Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, et al. (2000) Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 26: 163-175.
22. Ikeda K, Emoto N, Matsuo M and Yokoyama M (2003) Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals. J Biol Chem 278: 3514-3520.
23. Jenne DE, Kley RA, Vorgerd M, Schröder JM, Weis J, Reimann H, Albrecht B, Nürnberg P, Thiele H, Müller CR, Meng G, Witt C and Labeit S (2005) Limb girdle muscular dystrophy in a sibling pair with a homozygous Ser606Leu mutation in the alternatively spliced IS2 region of calpain 3. Biol Chem 386: 61-67.
24. Kawabata Y, Hata S, Ono Y, Ito Y, Suzuki K, Abe K and Sorimachi H (2003) Newly identified exons encoding novel variants of p94/calpain 3 are expressed ubiquitously and overlap the -glucosidase C gene. FEBS Lett 555: 623-630.
25. Keira Y, Noguchi S, Minami N, Hayashi YK and Nishino I (2003) Localization of calpain 3 in human skeletal muscle and its alteration in limb-girdle muscular dystrophy 2A muscle. J BioChem (Tokyo) 133: 659-664.
26. Kinbara K, Ishiura S, Tomioka S, Sorimachi H, Jeong S-Y, Amano S, Kawasaki H, Kolmerer B, Kimura S, Labeit S and Suzuki K (1998) Purification of native p94, a muscle-specific calpain, and characterization of its autolysis. BioChem J 335: 589-596.
27. Kinbara K, Sorimachi H, Ishiura S and Suzuki K (1997) Muscle-specific calpain, p94, interacts with the extreme C-terminal region of connectin, a unique region flanked by two immunoglobulin C2 motifs. Arch BioChem Biophys 342: 99-107.
28. Kuo H, Chen J, Ruiz-Lozano P, Zou Y, Nemer M and Chien KR (1999) Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in marine cardiogenesis. Devlopment 126: 4223-4234.
29. Labeit S, Gautel M, Lakey A and Trinick J (1992) Towards a molecular understanding of titin. EMBO J 11: 1711-1716.
30. Labeit S and Kolmerer B (1995) Titins: giant proteins in charge of muscle ultrastructure and elasticity. Science 270: 293-296.
31. Lecker SH, Jagoe RT, Gilbert A, Gomes M, Baracos V, Bailey J, Price SR, Mitch WE and Goldberg AL (2004) Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J 18: 39-51.
32. Ma H, Fukiage C, Azuma M and Shearer TR (1998) Cloning and expression of mRNA for calpain Lp82 from rat lens: splice variant of p94. Invest Ophthalmol Vis Sci 39: 454-461.
33. Maruyama K (1976) Connectin, an elastic protein from myofibrils. J BioChem 80: 405-407.
34. McElhinny AS, Kakinuma K, Sorimachi H, Labeit S and Gregorio CC (2002) Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1. J Cell Biol 157: 125-136.
35. Miller MK, Bang M-L, Witt CC, Labeit D, Trombitas C, Watanabe K, Granzier H, McElhinny AS, Gregorio CC and Labeit S (2003) The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules. J Mol Biol 333: 951-964.
36. Moreira ES, Wiltshire TJ, Faulkner G, Nilforoushan A, Vainzof M, Suzuki OT, Valle G, Reeves R, Zatz M, Passos-Bueno MR and Jenne DE (2000) Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin. Nat Genet 24: 163-166.
37. Moyen C, Goudenege S, Poussard S, Sassi AH, Brustis J-J and Cottin P (2004) Involvement of micro-calpain (CAPN 1) in muscle cell differentiation. Inter J BioChem Cell Biol 36: 728-743.
38. Mues A, Ven PFMvd , Young P, Fürst DO and Gautel M (1998) Two immunoglobulin-like domains of the Z-disc portion of titin interact in a conformation-dependent way with telethonin. FEBS Lett 428: 111-114.
39. Nikawa T, Ishidoh K, Hirasaka K, Ishihara I, Ikemoto M, Kano M, Kominami E, Nonaka I, Ogawa T, Adams GR, Baldwin KM, Yasui N and Kishi Takeda K S (2004) Skeletal muscle gene expression in space-flown rats. FASEB J 18: 522-524.
40. Ohtsuka H, Yajima H, Maruyama K and Kimura S (1997) Binding of the N-terminal 63 kDa portion of connectin/titin to alpha-actinin as Rev.ealed by the yeast two-hybrid system. FEBS Lett 401: 65-67.
41. Ojima K, Lin ZX, Zhang ZQ, Hijikata T, Holtzer S, Labeit S, Sweeney HL and Holtzer H ( 1999) Initiation and maturation of I-Z-I bodies in the growth tips of transfected myotubes. J Cell Sci 112: 4101-4112.
42. Ojima K, Uezumi A, Miyoshi H, Masuda S, Morita Y, Fukase A, Hattori A, Nakauchi H, Miyagoe-Suzuki Y and Takeda S (2004) Mac-1(low) early myeloid cells in the bone marrow-derived SP fraction migrate into injured skeletal muscle and participate in muscle regeneration. BioChem Biophys Res Commun 321: 1050-1061.
43. Ono Y, Shimada H, Sorimachi H, Richard I, Saido TC, Beckmann JS, Ishiura S and Suzuki K (1998) Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A. J Biol Chem 273: 17073-17078.
44. Pallavicini A, Kojic S, Bean C, Vainzof M, Salamon M, Levolella C, Bortoletto G, Pacchioni B, Zatz M, Lanfranchi G, Faulkner G and Valle G (2001) Characterization of human skeletal muscle Ankrd2. BioChem Biophys Res Commun 285: 378-386.
45. Raynaud F, Carnac G, Marcihac A and Benyamin Y (2004) m-calpain implication in cell cycle during muscle precursor activation. Exp Cell Res 298: 48-57.
46. 2+ dependent intramolecular autolysis. FEBS Lett 532: 401-406.
47. Richard I, Broux O, Allamand V, Fougerousse F, Chiannilkulchai N, Bourg N, Brenguier L, Devaud C, Pasturaud P, Roudaut C, Hillaire D, Passos-Bueno MR, Zatz M, Tischfield JA, Fardeau M, Jackson CE, Cohen D and Beckmann JS (1995) Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A. Cell 81: 27-40.
48. Saito K, Elce JS, Hamos JE and Nixon RA (1993) Widespread activation of calcium-activated neutral proteinase (Calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Pro Natl Acad Sci USA 90: 2628-2632.
49. Salmikangas P, Mykkanen OM, Gronholm M, Heiska L, Kere J and Carpen O (1999) Myotilin, a novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy. Hum Mol Genet 8: 1329-1336.
50. Sorimachi H, Freiburg A, Kolmerer B, Ishiura S, Stier G, Gregorio CC, Labeit D, Linke WA, Suzuki K and Labeit S (1997) Tissue-specific expression and alpha-actinin binding properties of the Z-disc titin: implications for the nature of vertebrate Z-discs. J Mol Biol 270: 688-695.
51. Sorimachi H, Kinbara K, Kimura S, Takahashi M, Ishiura S, Sasagawa N, Sorimachi N, Shimada H, Tagawa K, Maruyama K and Suzuki K (1995) Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence. J Biol Chem 270: 31158-31162.
52. Sorimachi H and Suzuki K (2001) The structure of calpain. J BioChem 129: 653-664.
53. Sorimachi H, Toyama-Sorimachi N, Saido TC, Kawasaki H, Sugita H, Miyasaka M, Arahata K, Ishiura S and Suzuki K (1993) Muscle-specific calpain, p94, is degraded by autolysis immediately after translation, resulting in disappearance from muscle. J Biol Chem 268: 10593-10605.
54. Soteriou A, Gamage M and Trinick J (1993) A survey of interactions made by the giant protein titin. J Cell Sci 104: 119-123.
55. Spencer MJ, Guyon JR, Sorimachi H, Potts A, Richard I, Herasse M, Chamberlain J, Dalkilic I, Kunkel LM and Beckmann JS (2002) Stable expression of calpain 3 from a muscle transgene in vivo: immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation. Proc Natl Acad Sci U S A 99: 8874-8879.
56. Suzuki K, Hata S, Kawabata Y and Sorimachi H (2004) Structure, activation, and Biol.ogy of calpain. Diabetes 53: S12-S18.
57. Tompa P (2002) Intrinsically unstructured proteins. Trends BioChem Sci 27: 523-533.
58. Tullio RD, Stifanese R, Salamino F, Pontremoli S and Melloni E (2003) Characterization of a new p94-like calpain form in human lymphocytes. BioChem J 375: 689-696.
59. Udd B, Partanen J, Halonen P, Falck B, Hakamies L, Heikkila H, Ingo S, Kalimo H, Kaariainen H, Laulumaa V, Paljarvi PL, Rapola J, Reunanen M, Sonninen V and Somer H (1993) Tibial muscular dystrophy. Late adult-onset distal myopathy in 66 Finnish patients. Arch Neurol 50: 604-608.
60. Valle G, Faulkner G, Antoni AD, Pacchioni B, Pallavicini A, Pandolfo D, Tiso N, Toppo S, Trevisan S and Lanfranchi G (1997) Telethonin, a novel sarcomeric protein of heart and skeletal muscle. FEBS Lett 415: 163-168.
61. Wang K, McClure J and Tu A (1979) Titin: major myofibrillar components of striated muscle. Pro Natl Acad Sci USA 76: 3698-3702.
62. Welm AL, Timchenko NA, Ono Y, Sorimachi H, Radomska HS, Tenen DG, Lekstrom-Himes J and Darlington GJ (2002) C/EBPα Is required for proteolytic cleavage of cyclin A by calpain 3 in myeloid precursor cells. J Biol Chem 277: 33848-33856.
63. Witt CC, Ono Y, Puschmann E, McNabb M, Wu Y, Gotthardt M, Witt SH, Haak M, Labeit D, Gregorio CC, Sorimachi H, Granzier H and Labeit S (2004) Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling. J Mol Biol 336: 145-154.
64. Zou Y, Evans S, Chen J, Kuo HC, Harvey RP and Chien KR (1997) CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. Development 124: 793-804.