The NH2 terminus of titin spans the Z-disc: Its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity

Journal of Cell Biology

Volumn 143, Issue 4, 1998, Pages 1013-1027

  Gregorio, Carol C ^a   Trombitás, Karoly ^d   Centner, Thomas ^b   Kolmerer, Bernhard ^b   Stier, Gunter ^b   Kunke, Kathleen ^a   Suzuki, Koichi ^c   Obermayr, Franz ^e   Herrmann, Bernhard ^e   Granzier, Henk ^d   Sorimachi, Hiroyuki ^c   Labeit, Siegfried ^b  

^a UNIVERSITY OF ARIZONA   (United States)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c UNIVERSITY OF TOKYO   (Japan)

^d WASHINGTON STATE UNIVERSITY   (United States)

^e MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

actinin; Sarcomere; Titin; Titin cap (T cap); Z disc

Indexed keywords

ALPHA ACTININ; CONNECTIN; ACTININ; MEMBRANE PROTEIN; MUSCLE PROTEIN; PROTEIN KINASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN STRUCTURE; SARCOMERE; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CHEMISTRY; CHICK EMBRYO; CYTOLOGY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETICS; HEART MUSCLE; IMMUNOELECTRON MICROSCOPY; METABOLISM; MOLECULAR GENETICS; MUSCLE CELL; MUSCLE FIBRIL; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SKELETAL MUSCLE; ULTRASTRUCTURE;

ACTININ; AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; CHICK EMBRYO; GENE EXPRESSION; MEMBRANE PROTEINS; MICROSCOPY, IMMUNOELECTRON; MOLECULAR SEQUENCE DATA; MUSCLE FIBERS; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYOCARDIUM; MYOFIBRILS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; SARCOMERES; TRANSCRIPTION, GENETIC;

EID: 0032538660     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.143.4.1013     Document Type: Article

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