Lipophilic analogs of thioflavin S as novel amyloid-imaging agents

Current Alzheimer Research

Volumn 3, Issue 3, 2006, Pages 259-266

  Wu, Chunying ^a   Cai, Lisheng ^b   Wei, Jingjun ^a   Pike, Victor W ^b   Wang, Yanming ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Alzheimer's disease; Amyloid ; Imaging; PET; SPECT; Thioflavin S

Indexed keywords

4 [(2,6') BIBENZOTHIAZOLYL 2' YL)ANILINE; 4 [(2,6') BIBENZOTHIAZOLYL 2' YL)ANILINE I 125; 4 [6 METHYL (2,6') BIBENZOTHIAZOLYL 2' YL)ANILINE; 4 [6 METHYL (2,6') BIBENZOTHIAZOLYL 2' YL)ANILINE I 125; AMYLOID; CARBON 11; FLUORESCENT DYE; IODINE 125; N METHYL 4 [(2,6') BIBENZOTHIAZOLYL 2' YL)ANILINE; N METHYL 4 [6 METHYL (2,6') BIBENZOTHIAZOLYL 2' YL)ANILINE; RADIOISOTOPE; THIOFLAVINE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPSY; BINDING AFFINITY; BRAIN; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIPOPHILICITY; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

AFFINITY LABELS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BINDING, COMPETITIVE; CARBON RADIOISOTOPES; DIAGNOSTIC IMAGING; DRUG EVALUATION, PRECLINICAL; FLUORESCENT DYES; HUMANS; IODINE RADIOISOTOPES; MICE; MOLECULAR STRUCTURE; NEUROFIBRILLARY TANGLES; PROTEIN BINDING; RADIOPHARMACEUTICALS; SENILE PLAQUES; THIAZOLES;

EID: 33745585068     PISSN: 15672050     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720506777632862     Document Type: Article

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