Technetium complexes for the quantitation of brain amyloid

Journal of the American Chemical Society

Volumn 118, Issue 18, 1996, Pages 4506-4507

  Han, Hogyu ^a   Cho, Cheon Gyu ^a,b   Lansbury Jr , Peter T ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; TECHNETIUM 99M;

ALZHEIMER DISEASE; ARTICLE; CHROMOSOME HIGH RESOLUTION BANDING ANALYSIS; DRUG BRAIN LEVEL; NONHUMAN; REACTION ANALYSIS; SENILE PLAQUE; SEQUENCE HOMOLOGY; TISSUE SECTION;

EID: 15844405638     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja960207l     Document Type: Article

References (44)

1. (a) Alzheimer, A. Allg. Z. Psychiatr. Psych. Gerichtl. Med. 1907, 64, 146.
2. (b) Katzman, R.; Saitoh, T. FASEB J. 1991, 5, 278-286.
3. (c) Puchtler, H.; Sweat F.; Levine, M. J. Histochem. Cytochem. 1962, 10, 355-364.
4. (d) Wolman, M.; Bubis, J. J. Histochemie 1965, 4, 351-356.
5. (e) Benditt, E. P.; Eriksen, N.; Berglund, C. Proc. Natl. Acad. Sci. U.S.A. 1970, 66, 1044-1051.
6. (f) Taylor, D. L.; Allen, R. D.; Benditt, E. P. J. Histochem. Cytochem. 1974, 22, 1105-1112.
7. (g) Klunk, W. E.; Pettegrew, J. W.; Abraham, D. J. J. Histochem. Cytochem. 1989, 37, 1273-1281.
8. (h) Klunk, W. E.; Pettegrew, J. W.; Abraham, D. J. J. Histochem. Cytochem. 1989, 37, 1293-1297.
9. 3.15
10. (a) Selkoe, D. J. J. NIH Research 1995, 7, 57-64.
11. (b) Cordell, B. Ann. Rev. Pharmacol. Toxicol. 1994, 34, 69-89.
12. (c) Schenk, D. B.; Rydel, R. E.; May, P ; Little, S.; Panetta, J.; Lieberburg, I.; Sinha, S. J. Med. Chem. 1995, 38, 4141-4154.
13. (a) Edwards, R. J.; Clinton, J.; Gentleman, S. M.; Roberts, G. W.; Royston, M. C. Neurodegener. 1992, 1, 65-71.
14. (b) Polvikoski, T., et al. N. Engl. J. Med. 1995, 333, 1242-1247.
15. (c) Hyman, B. T., et al. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 3586-3590.
16. (d) Cummings, B. J.; Carman, C. W. Lancet 1995, 346, 1524-1528.
17. 3
18. (a) Glenner, G. G.; Eanes, E. D.; Page, D. L. J. Histochem. Cytochem. 1972, 20, 821-826.
19. (b) Glenner, G. G. N. Engl. J. Med. 1980, 302, 1333-1343.
20. (c) Cooper, J. H. Lab. Invest. 1974, 31, 232-238.
21. (d) Turnell, W. G.; Finch, J. T. J. Mol. Biol. 1992, 227, 1205-1233.
22. (a) Lansbury, P. T., Jr. Biochemistry 1992, 31, 6865-6870.
23. (b) Lansbury, P. T., Jr.; Costa, P. R.; Griffiths, J. M ; Simon, E. J.; Auger, M.; Halverson, K. J., Kocisko, D. A.; Hendsch, Z. S.; Ashbum, T. T.; Spencer, R. G. S.; Tidor, B.; Griffin, R. G. Nature Struct. Biol. 1995, 2, 990-998.
24. (a) Klunk, W. E.; Debnath, M. L.; Pettegrew, J. W. Neurobiol. Aging 1994, 15, 691-698.
25. (b) Klunk, W. E., Debnath, M. L.; Pettegrew, J. W. Neurobiol. Aging 1995, 16, 541-548.
26. Ashburn, T. T.; Han, H.; McGuinness, B. F.; Lansbury, P. T., Jr. Chem. Biol., in press.
27. (a) Abrams, M. J.; Murrer, B. A. Science 1993, 261, 725-730.
28. (b) Meegalla, S.; Plössl, K.; Kung, M.-P.; Stevenson, D. A.; Liable-Sands, L. M.; Rheingold, A. L.; Kung, H. F. J. Am. Chem. Soc. 1995, 117, 11037-11038.
29. (a) Park, T. K. Ph.D. Thesis, Massachusetts Institute of Technology, Cambridge, MA, 1992; pp 94-98, 170-173.
30. (b) Knorpp, C. T.; Rennie, M. H.; Korst, D. R. J. Nucl. Med. 1960, 1, 23-30.
31. (c) Calogero, F.; Freeman, H. S.; Esancy, J. F.; Whaley, W. M. Dyes Pigm. 1987, 8, 431-447.
32. (a) O'Connell, L. A.; Dewan, J.; Jones, A. G.; Davison, A. Inorg. Chem. 1990, 29, 3539-3547.
33. (b) Abrams, M. J.; Davison, A.; Jones, A. G.; Costello, C. E.; Pang, H. Inorg. Chem. 1983, 22, 2798-2800.
34. Juhasz, P.; Biemann, K. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 4333-4337.
35. 2 indicated that a 2:1 2:Zn complex was formed.
36. NAC (Figure 1) may represent up to 10% by moles of AD brain amyloid fibrils. NAC fibrils seed polymerization of β1-40 in vitro and vice versa. Han, H.; Weinreb, P. H.; Lansbury, P. T., Jr. Chem. Biol. 1995, 2, 163-169.
37. 9 Thus, it may be possible to develop protein-specific amyloid probes.
38. Kozarich, J. W.; Musso, G. F.; Malfroy-Camine, B. U.S. Patent 5 268 164, 1993; Chem. Abstr. 1993, 119, 836.
39. (a) Kagan, D. Z.; Rozinova, V. N. Probl. Tuberk. 1974, 9, 72-74.
40. (b) Caughey, B.; Race, R. E. J. Neurochem. 1992, 59, 768-771.
41. (c) Caughey, B.; Ernst, D.; Race, R. E. J. Virol. 1993, 67, 6270-6272.
42. (d) Saito, Y.; Buciak, J.; Yang, J.; Pardridge, W. M. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 10227-10231.
43. Freifelder, D. Physical Biochemistry: Applications to Biochemistry and Molecular Biology, 2nd ed.; W. H. Freeman and Company: New York, 1982; Chapter 10, p 654.
44. Cheng, Y. -C.; Prusoff, W. H. Biochem. Pharmacol. 1973, 22, 3099-3108.