Benzofuran derivatives as Aβ-aggregate-specific imaging agents for Alzheimer's disease

Nuclear Medicine and Biology

Volumn 29, Issue 6, 2002, Pages 633-642

  Ono, Masahiro ^a   Kung, Mei Ping ^a   Hou, Catherine ^a   Kung, Hank F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

A aggregates; Iodinated ligands; SPECT imaging

Indexed keywords

5 IODO 2 (4 DIMETHYLAMINOPHENYL)BENZOFURAN I 125; 5 IODO 2 (4 HYDROXYPHENYL)BENZOFURAN I 125; 5 IODO 2 (4 METHYLAMINOPHENYL)BENZOFURAN I 125; 6 IODO 2 (4 DIMETHYLAMINOPHENYL)BENZOFURAN I 125; AMYLOID BETA PROTEIN; BENZOFURAN DERIVATIVE; HYDROGEN PEROXIDE; THIOFLAVINE; TRIBUTYLTIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; DIAGNOSTIC AGENT; RADIOACTIVE IODINE; RADIOPHARMACEUTICAL AGENT;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ARTICLE; BINDING COMPETITION; BINDING KINETICS; CONTROLLED STUDY; DISEASE COURSE; DRUG DISTRIBUTION; DRUG SYNTHESIS; IODINATION; MOUSE; NONHUMAN; OXIDATION; PROTEIN AGGREGATION; RADIOACTIVITY; ANIMAL; BRAIN; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; EVALUATION; IN VITRO STUDY; ISOTOPE LABELING; METABOLISM; METHODOLOGY; SCINTISCANNING; SYNTHESIS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BENZOFURANS; BIOLOGICAL MARKERS; BRAIN; IODINE RADIOISOTOPES; ISOTOPE LABELING; MICE; MODELS, CHEMICAL; MODELS, MOLECULAR; RADIOPHARMACEUTICALS;

EID: 0036668810     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(02)00326-8     Document Type: Article

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