-
1
-
-
14844327296
-
Ulcerative colitis: Clinical presentation and diagnosis
-
Satsangi J and Sutherland LR, eds. New York: Churchill Livingstone
-
Travis S, Jewell DP. Ulcerative colitis: clinical presentation and diagnosis. In: Satsangi J and Sutherland LR, eds. Inflammatory Bowel Disease. New York: Churchill Livingstone, 2003: 169-182
-
(2003)
Inflammatory Bowel Disease
, pp. 169-182
-
-
Travis, S.1
Jewell, D.P.2
-
2
-
-
12344285592
-
Clinical presentation and diagnosis of Crohn's disease
-
Satsangi J and Sutherland L, eds. New York: Churchill Livingstone
-
Forbes A. Clinical presentation and diagnosis of Crohn's disease. In: Satsangi J and Sutherland L, eds. Inflammatory Bowel Disease. New York: Churchill Livingstone, 2003: 183-189
-
(2003)
Inflammatory Bowel Disease
, pp. 183-189
-
-
Forbes, A.1
-
3
-
-
2342445762
-
Management of inflammatory bowel disease
-
Nayar M, Rhodes JM. Management of inflammatory bowel disease. Postgrad Med J 2004; 80: 206-213
-
(2004)
Postgrad Med J
, vol.80
, pp. 206-213
-
-
Nayar, M.1
Rhodes, J.M.2
-
5
-
-
28844473957
-
Infliximab for induction and maintenance therapy for ulcerative colitis
-
Rutgeerts F, Sandborn WJ, Feagan BG, Reinisch W, Olson A, Johanns J, Travers S, Rachmilewitz D, Hanauer SB, Lichtenstein GR, de Villiers WJ, Present D, Sands BE, Colombel JF. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005; 353: 2462-2476
-
(2005)
N Engl J Med
, vol.353
, pp. 2462-2476
-
-
Rutgeerts, F.1
Sandborn, W.J.2
Feagan, B.G.3
Reinisch, W.4
Olson, A.5
Johanns, J.6
Travers, S.7
Rachmilewitz, D.8
Hanauer, S.B.9
Lichtenstein, G.R.10
de Villiers, W.J.11
Present, D.12
Sands, B.E.13
Colombel, J.F.14
-
6
-
-
20444487429
-
Infliximab induction and maintenance therapy for ulcerative colitis: The ACT2 trial
-
Sandborn W, Rachmilewitz D, Hanauer SB, Lichtenstein G, de Villiers W, Olson A, Johanns J, Travers S. Infliximab induction and maintenance therapy for ulcerative colitis: the ACT2 trial. Gastroenterology 2005; 128: A688
-
(2005)
Gastroenterology
, vol.128
-
-
Sandborn, W.1
Rachmilewitz, D.2
Hanauer, S.B.3
Lichtenstein, G.4
de Villiers, W.5
Olson, A.6
Johanns, J.7
Travers, S.8
-
7
-
-
0034214336
-
A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease
-
North American Crohn's Study Group Investigators
-
Feagan BG, Fedorak RN, Irvine EJ, Wild G, Sutherland L, Steinhart AH, Greenberg GR, Koval J, Wong Cj, Hopkins M, Hanauer SB, McDonald JW. A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators. N Engl J Med 2000; 342: 1627-1632
-
(2000)
N Engl J Med
, vol.342
, pp. 1627-1632
-
-
Feagan, B.G.1
Fedorak, R.N.2
Irvine, E.J.3
Wild, G.4
Sutherland, L.5
Steinhart, A.H.6
Greenberg, G.R.7
Koval, J.8
Wong, C.J.9
Hopkins, M.10
Hanauer, S.B.11
McDonald, J.W.12
-
8
-
-
21344472474
-
Oral 5-aminosalicylic acid for maintenance of medically-induced remission in Crohn's Disease
-
CD003715
-
Akobeng AK, Gardener E. Oral 5-aminosalicylic acid for maintenance of medically-induced remission in Crohn's Disease. Cochrane Database Syst Rev, 2005: CD003715
-
(2005)
Cochrane Database Syst Rev
-
-
Akobeng, A.K.1
Gardener, E.2
-
9
-
-
2442560241
-
Optimizing anti-TNF treatment in inflammatory bowel disease
-
Rutgeerts P, Van Assche G, Vermeire S. Optimizing anti-TNF treatment in inflammatory bowel disease. Gastroenterology 2004; 126: 1593-1610
-
(2004)
Gastroenterology
, vol.126
, pp. 1593-1610
-
-
Rutgeerts, P.1
Van Assche, G.2
Vermeire, S.3
-
10
-
-
0037421590
-
Pharmacogenomics - Drug disposition, drug targets, and side effects
-
Evans WE, McLeod HL. Pharmacogenomics - drug disposition, drug targets, and side effects. N Engl J Med 2003; 348: 538-549
-
(2003)
N Engl J Med
, vol.348
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
11
-
-
23844516328
-
Pharmacogenetics-based therapeutic recommendations - Ready for clinical practice?
-
Kirchheiner J, Fuhr U, Brockmoller J. Pharmacogenetics-based therapeutic recommendations - ready for clinical practice? Nat Rev Drug Discov 2005; 4: 639-647
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 639-647
-
-
Kirchheiner, J.1
Fuhr, U.2
Brockmoller, J.3
-
13
-
-
84921430591
-
Azathioprine or 6-mercaptopurine for inducing remission of Crohn's disease
-
CD000545
-
Sandborn W, Sutherland L, Pearson D, May G, Modigliani R, Prantera C. Azathioprine or 6-mercaptopurine for inducing remission of Crohn's disease. Cochrane Database Syst Rev, 2000: CD000545
-
(2000)
Cochrane Database Syst Rev
-
-
Sandborn, W.1
Sutherland, L.2
Pearson, D.3
May, G.4
Modigliani, R.5
Prantera, C.6
-
14
-
-
11144266571
-
Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype
-
Arnott ID, Landers CJ, Nimmo EJ, Drummond HE, Smith BK, Targan SR, Satsangi J. Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype. Am J Gastroenterol 2004; 99: 2376-2384
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 2376-2384
-
-
Arnott, I.D.1
Landers, C.J.2
Nimmo, E.J.3
Drummond, H.E.4
Smith, B.K.5
Targan, S.R.6
Satsangi, J.7
-
15
-
-
3142660552
-
A prospective randomized observer-blind 2-year trial of azathioprine monotherapy versus azathioprine and olsalazine for the maintenance of remission of steroid-dependent ulcerative colitis
-
Mantzaris GJ, Sfakianakis M, Archavlis E, Petraki K, Christidou A, Karagiannidis A, Triadaphyllou G. A prospective randomized observer-blind 2-year trial of azathioprine monotherapy versus azathioprine and olsalazine for the maintenance of remission of steroid-dependent ulcerative colitis. Am J Gastroenterol 2004; 99: 1122-1128
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 1122-1128
-
-
Mantzaris, G.J.1
Sfakianakis, M.2
Archavlis, E.3
Petraki, K.4
Christidou, A.5
Karagiannidis, A.6
Triadaphyllou, G.7
-
16
-
-
0036278519
-
The efficacy of azathioprine for the treatment of inflammatory bowel disease: A 30 year review
-
Fraser AG, Orchard TR, Jewell DP. The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 2002; 50: 485-489
-
(2002)
Gut
, vol.50
, pp. 485-489
-
-
Fraser, A.G.1
Orchard, T.R.2
Jewell, D.P.3
-
17
-
-
0027164795
-
Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience
-
Connell WR, Kamm MA, Ritchie JK, Lennard-Jones JE. Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience. Gut 1993; 34: 1081-1085
-
(1993)
Gut
, vol.34
, pp. 1081-1085
-
-
Connell, W.R.1
Kamm, M.A.2
Ritchie, J.K.3
Lennard-Jones, J.E.4
-
18
-
-
0024457688
-
6-Mercaptopurine in the management of inflammatory bowel disease: Short- and long-term toxicity
-
Present DH, Meltzer SJ, Krumholz MP, Wolke A, Korelitz BI. 6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity. Ann Intern Med 1989; 111: 641-649
-
(1989)
Ann Intern Med
, vol.111
, pp. 641-649
-
-
Present, D.H.1
Meltzer, S.J.2
Krumholz, M.P.3
Wolke, A.4
Korelitz, B.I.5
-
19
-
-
0029073930
-
Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase
-
Krynetski EY, Krynetskaia NF, Yanishevski Y, Evans WE. Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase. Mol Pharmacol 1995; 47: 1141-1147
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1141-1147
-
-
Krynetski, E.Y.1
Krynetskaia, N.F.2
Yanishevski, Y.3
Evans, W.E.4
-
20
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 1992; 43: 329-339
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
21
-
-
0242464926
-
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes
-
Tiede I, Fritz G, Strand S, Poppe D, Dvorsky R, Strand D, Lehr HA, Wirtz S, Becker C, Atreya R, Mudter J, Hildner K, Bartsch B, Holtmann M, Blumberg R, Walczak H, Iven H, Galle PR, Ahmadian MR, Neurath MF. CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J Clin Invest 2003; 111: 1133-1145
-
(2003)
J Clin Invest
, vol.111
, pp. 1133-1145
-
-
Tiede, I.1
Fritz, G.2
Strand, S.3
Poppe, D.4
Dvorsky, R.5
Strand, D.6
Lehr, H.A.7
Wirtz, S.8
Becker, C.9
Atreya, R.10
Mudter, J.11
Hildner, K.12
Bartsch, B.13
Holtmann, M.14
Blumberg, R.15
Walczak, H.16
Iven, H.17
Galle, P.R.18
Ahmadian, M.R.19
Neurath, M.F.20
more..
-
22
-
-
0027308959
-
The importance of methylthio-IMP for methylmercaptopurine ribonucleoside (Me-MPR) cytotoxicity in Molt F4 human malignant T-lymphoblasts
-
Vogt MH, Stet EH, De Abreu RA, Bokkerink JP, Lambooy LH, Trijbels FJ. The importance of methylthio-IMP for methylmercaptopurine ribonucleoside (Me-MPR) cytotoxicity in Molt F4 human malignant T-lymphoblasts. Biochim Biophys Acta 1993; 1181: 189-194
-
(1993)
Biochim Biophys Acta
, vol.1181
, pp. 189-194
-
-
Vogt, M.H.1
Stet, E.H.2
De Abreu, R.A.3
Bokkerink, J.P.4
Lambooy, L.H.5
Trijbels, F.J.6
-
23
-
-
0018822866
-
Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
-
Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 1980; 32: 651-662
-
(1980)
Am J Hum Genet
, vol.32
, pp. 651-662
-
-
Weinshilboum, R.M.1
Sladek, S.L.2
-
24
-
-
4344579337
-
Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy
-
Evans WE. Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy. Ther Drug Monit 2004; 26: 186-191
-
(2004)
Ther Drug Monit
, vol.26
, pp. 186-191
-
-
Evans, W.E.1
-
25
-
-
0034050713
-
Screening of thiopurine S-methyltransferase mutations by horizontal conformation-sensitive gel electrophoresis
-
Alves S, Prata MJ, Ferreira F, Amorim A. Screening of thiopurine S-methyltransferase mutations by horizontal conformation-sensitive gel electrophoresis. Hum Mutat 2000; 15: 246-253
-
(2000)
Hum Mutat
, vol.15
, pp. 246-253
-
-
Alves, S.1
Prata, M.J.2
Ferreira, F.3
Amorim, A.4
-
26
-
-
1942435574
-
Identification of two novel sequence variants affecting thiopurine methyltransferase enzyme activity
-
Lindqvist M, Haglund S, Almer S, Peterson C, Taipalensu J, Hertervig E, Lyrenas E, Soderkvist P. Identification of two novel sequence variants affecting thiopurine methyltransferase enzyme activity. Pharmacogenetics 2004; 14: 261-265
-
(2004)
Pharmacogenetics
, vol.14
, pp. 261-265
-
-
Lindqvist, M.1
Haglund, S.2
Almer, S.3
Peterson, C.4
Taipalensu, J.5
Hertervig, E.6
Lyrenas, E.7
Soderkvist, P.8
-
28
-
-
24044550689
-
PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
-
Wigginton JE, Abecasis GR. PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 2005; 21: 3445-3447
-
(2005)
Bioinformatics
, vol.21
, pp. 3445-3447
-
-
Wigginton, J.E.1
Abecasis, G.R.2
-
29
-
-
0034034158
-
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
-
McLeod HL, Krynetski EY, Relling MV, Evans WE. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia. Leukemia 2000; 14: 567-572
-
(2000)
Leukemia
, vol.14
, pp. 567-572
-
-
McLeod, H.L.1
Krynetski, E.Y.2
Relling, M.V.3
Evans, W.E.4
-
30
-
-
0033828949
-
Genetic polymorphism of thiopurine S-methyltransferase: Molecular mechanisms and clinical importance
-
Krynetski EY, Evans WE. Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance. Pharmacology 2000; 61: 136-146
-
(2000)
Pharmacology
, vol.61
, pp. 136-146
-
-
Krynetski, E.Y.1
Evans, W.E.2
-
31
-
-
27744461917
-
Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
-
Gearry RB, Barclay ML. Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease. J Gastroenterol Hepatol 2005; 20: 1149-1157
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 1149-1157
-
-
Gearry, R.B.1
Barclay, M.L.2
-
32
-
-
0028861745
-
A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase
-
Krynetski EY, Schuetz JD, Galpin AJ, Pui CH, Relling MV, Evans WE. A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Proc Natl Acad Sci USA 1995; 92: 949-953
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 949-953
-
-
Krynetski, E.Y.1
Schuetz, J.D.2
Galpin, A.J.3
Pui, C.H.4
Relling, M.V.5
Evans, W.E.6
-
33
-
-
0031820555
-
Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans
-
Loennechen T, Yates CR, Fessing MY, Relling MV, Krynetski EY, Evans WE. Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans. Clin Pharmacol Ther 1998; 64: 46-51
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 46-51
-
-
Loennechen, T.1
Yates, C.R.2
Fessing, M.Y.3
Relling, M.V.4
Krynetski, E.Y.5
Evans, W.E.6
-
34
-
-
3242704015
-
Thiopurine methyltransferase: Should it be measured before commencing thiopurine drug therapy?
-
Sanderson J, Ansari A, Marinaki T, Duley J. Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy? Ann Clin Biochem 2004; 41: 294-302
-
(2004)
Ann Clin Biochem
, vol.41
, pp. 294-302
-
-
Sanderson, J.1
Ansari, A.2
Marinaki, T.3
Duley, J.4
-
35
-
-
2542639314
-
Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: Implications for therapy
-
Derijks LJ, Gilissen LP, Engels LG, Bos LP, Bus PJ, Lohman JJ, Curvers WL, Van Deventer SJ, Hommes DW, Hooymans PM. Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy. Ther Drug Monit 2004; 26: 311-318
-
(2004)
Ther Drug Monit
, vol.26
, pp. 311-318
-
-
Derijks, L.J.1
Gilissen, L.P.2
Engels, L.G.3
Bos, L.P.4
Bus, P.J.5
Lohman, J.J.6
Curvers, W.L.7
Van Deventer, S.J.8
Hommes, D.W.9
Hooymans, P.M.10
-
36
-
-
3142628214
-
Some cases demonstrating the clinical usefulness of therapeutic drug monitoring in thiopurine-treated inflammatory bowel disease patients
-
Gilissen LP, Derijks LJ, Bos LP, Verhoeven HM, Bus PJ, Hooymans PM, Engels LG. Some cases demonstrating the clinical usefulness of therapeutic drug monitoring in thiopurine-treated inflammatory bowel disease patients. Eur J Gastroenterol Hepatol 2004; 16: 705-710
-
(2004)
Eur J Gastroenterol Hepatol
, vol.16
, pp. 705-710
-
-
Gilissen, L.P.1
Derijks, L.J.2
Bos, L.P.3
Verhoeven, H.M.4
Bus, P.J.5
Hooymans, P.M.6
Engels, L.G.7
-
37
-
-
0036790212
-
Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease
-
Ansari A, Hassan C, Duley J, Marinaki A, Shobowale-Bakre EM, Seed P, Meenan J, Yim A, Sanderson J. Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease. Aliment Pharmacol Ther 2002; 16: 1743-1750
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 1743-1750
-
-
Ansari, A.1
Hassan, C.2
Duley, J.3
Marinaki, A.4
Shobowale-Bakre, E.M.5
Seed, P.6
Meenan, J.7
Yim, A.8
Sanderson, J.9
-
38
-
-
0035037706
-
Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease
-
Cuffari C, Hunt S, Bayless T. Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease. Gut 2001; 48: 642-646
-
(2001)
Gut
, vol.48
, pp. 642-646
-
-
Cuffari, C.1
Hunt, S.2
Bayless, T.3
-
39
-
-
0034093057
-
Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy
-
Colombel JF, Ferrari N, Debuysere H, Marteau P, Gendre JP, Bonaz B, Soule JC, Modigliani R, Touze Y, Catala P, Libersa C, Broly F. Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy. Gastroenterology 2000; 118: 1025-1030
-
(2000)
Gastroenterology
, vol.118
, pp. 1025-1030
-
-
Colombel, J.F.1
Ferrari, N.2
Debuysere, H.3
Marteau, P.4
Gendre, J.P.5
Bonaz, B.6
Soule, J.C.7
Modigliani, R.8
Touze, Y.9
Catala, P.10
Libersa, C.11
Broly, F.12
-
40
-
-
0032212759
-
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine
-
Black AJ, McLeod HL, Capell HA, Powrie RH, Matowe LK, Pritchard SC, Collie-Duguid ES, Reid DM. Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine. Ann Intern Med 1998; 129: 716-718
-
(1998)
Ann Intern Med
, vol.129
, pp. 716-718
-
-
Black, A.J.1
McLeod, H.L.2
Capell, H.A.3
Powrie, R.H.4
Matowe, L.K.5
Pritchard, S.C.6
Collie-Duguid, E.S.7
Reid, D.M.8
-
41
-
-
0035871560
-
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
-
Evans WE, Hon YY, Bomgaars L, Coutre S, Holdsworth M, Janco R, Kalwinsky D, Keller F, Khatib Z, Margolin J, Murray J, Quinn J, Ravindranath Y, Ritchey K, Roberts W, Rogers ZR, Schiff D, Steuber C, Tucci F, Kornegay N, Krynetski EY, Relling MV. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol 2001; 19: 2293-2301
-
(2001)
J Clin Oncol
, vol.19
, pp. 2293-2301
-
-
Evans, W.E.1
Hon, Y.Y.2
Bomgaars, L.3
Coutre, S.4
Holdsworth, M.5
Janco, R.6
Kalwinsky, D.7
Keller, F.8
Khatib, Z.9
Margolin, J.10
Murray, J.11
Quinn, J.12
Ravindranath, Y.13
Ritchey, K.14
Roberts, W.15
Rogers, Z.R.16
Schiff, D.17
Steuber, C.18
Tucci, F.19
Kornegay, N.20
Krynetski, E.Y.21
Relling, M.V.22
more..
-
42
-
-
0037237923
-
Clinical use and practical application of TPMT enzyme and 6-mercaptopurine metabolite monitoring in IBD
-
Seidman EG. Clinical use and practical application of TPMT enzyme and 6-mercaptopurine metabolite monitoring in IBD. Rev Gastroenterol Disord 2003; 3 Suppl 1: S30-38
-
(2003)
Rev Gastroenterol Disord
, vol.3
, Issue.SUPPL. 1
-
-
Seidman, E.G.1
-
43
-
-
0037214334
-
Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine
-
Kaskas BA, Louis E, Hindorf U, Schaeffeler E, Deflandre J, Graepler F, Schmiegelow K, Gregor M, Zanger UM, Eichelbaum M, Schwab M. Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine. Gut 2003; 52: 140-142
-
(2003)
Gut
, vol.52
, pp. 140-142
-
-
Kaskas, B.A.1
Louis, E.2
Hindorf, U.3
Schaeffeler, E.4
Deflandre, J.5
Graepler, F.6
Schmiegelow, K.7
Gregor, M.8
Zanger, U.M.9
Eichelbaum, M.10
Schwab, M.11
-
44
-
-
12144285961
-
Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase)
-
Marinaki AM, Ansari A, Duley JA, Arenas M, Sumi S, Lewis CM, Shobowale-Bakre el-M, Escuredo E, Fairbanks LD, Sanderson JD. Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase), Pharmacogenetics 2004; 14: 181-187
-
(2004)
Pharmacogenetics
, vol.14
, pp. 181-187
-
-
Marinaki, A.M.1
Ansari, A.2
Duley, J.A.3
Arenas, M.4
Sumi, S.5
Lewis, C.M.6
Shobowale-Bakre, el-M.7
Escuredo, E.8
Fairbanks, L.D.9
Sanderson, J.D.10
-
45
-
-
0034771188
-
Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
-
Lowry PW, Franklin CL, Weaver AL, Pike MG, Mays DC, Tremaine WJ, Lipsky JJ, Sandborn WJ. Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut 2001; 49: 665-670
-
(2001)
Gut
, vol.49
, pp. 665-670
-
-
Lowry, P.W.1
Franklin, C.L.2
Weaver, A.L.3
Pike, M.G.4
Mays, D.C.5
Tremaine, W.J.6
Lipsky, J.J.7
Sandborn, W.J.8
-
46
-
-
10744223009
-
Pharmacological monitoring of azathioprine therapy
-
Reuther LO, Sonne J, Larsen NE, Larsen B, Christensen S, Rasmussen SN, Tofteng F, Haaber A, Johansen N, Kjeldsen J, Schmiegelow K. Pharmacological monitoring of azathioprine therapy. Scand J Gastroenterol 2003; 38: 972-977
-
(2003)
Scand J Gastroenterol
, vol.38
, pp. 972-977
-
-
Reuther, L.O.1
Sonne, J.2
Larsen, N.E.3
Larsen, B.4
Christensen, S.5
Rasmussen, S.N.6
Tofteng, F.7
Haaber, A.8
Johansen, N.9
Kjeldsen, J.10
Schmiegelow, K.11
-
47
-
-
0036189321
-
Relevance of thiopurine methyltransferase activity in inflammatory bowel disease patients maintained on low-dose azathioprine
-
Campbell S, Kingstone K, Ghosh S. Relevance of thiopurine methyltransferase activity in inflammatory bowel disease patients maintained on low-dose azathioprine. Aliment Pharmacol Ther 2002; 16: 389-398
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 389-398
-
-
Campbell, S.1
Kingstone, K.2
Ghosh, S.3
-
48
-
-
0036202803
-
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
-
Dubinsky MC, Yang H, Hassard PV, Seidman EG, Kam LY, Abreu MT, Targan SR, Vasiliauskas EA. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 2002; 122: 904-915
-
(2002)
Gastroenterology
, vol.122
, pp. 904-915
-
-
Dubinsky, M.C.1
Yang, H.2
Hassard, P.V.3
Seidman, E.G.4
Kam, L.Y.5
Abreu, M.T.6
Targan, S.R.7
Vasiliauskas, E.A.8
-
49
-
-
0035431092
-
Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only
-
Schwab M, Schaeffeler E, Marx C, Zanger U, Aulitzky W, Eichelbaum M. Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only. Gastroenterology 2001; 121: 498-499
-
(2001)
Gastroenterology
, vol.121
, pp. 498-499
-
-
Schwab, M.1
Schaeffeler, E.2
Marx, C.3
Zanger, U.4
Aulitzky, W.5
Eichelbaum, M.6
-
50
-
-
0034780344
-
Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide
-
Lowry PW, Franklin CL, Weaver AL, Szumlanski CL, Mays DC, Loftus EV, Tremaine WJ, Lipsky JJ, Weinshilboum RM, Sandborn WJ. Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide. Gut 2001; 49: 656-664
-
(2001)
Gut
, vol.49
, pp. 656-664
-
-
Lowry, P.W.1
Franklin, C.L.2
Weaver, A.L.3
Szumlanski, C.L.4
Mays, D.C.5
Loftus, E.V.6
Tremaine, W.J.7
Lipsky, J.J.8
Weinshilboum, R.M.9
Sandborn, W.J.10
-
51
-
-
0030011484
-
Intraindividual variability in red blood cell thiopurine methyltransferase activity
-
Giverhaug T, Klemetsdal B, Lysaa R, Aarbakke J. Intraindividual variability in red blood cell thiopurine methyltransferase activity. Eur J Clin Pharmacol 1996; 50: 217-220
-
(1996)
Eur J Clin Pharmacol
, vol.50
, pp. 217-220
-
-
Giverhaug, T.1
Klemetsdal, B.2
Lysaa, R.3
Aarbakke, J.4
-
52
-
-
0035031348
-
Human thiopurine S-methyltransferase activity in uremia and after renal transplantation
-
Weyer N, Kroplin T, Fricke L, Iven H. Human thiopurine S-methyltransferase activity in uremia and after renal transplantation. Eur J Clin Pharmacol 2001; 57: 129-136
-
(2001)
Eur J Clin Pharmacol
, vol.57
, pp. 129-136
-
-
Weyer, N.1
Kroplin, T.2
Fricke, L.3
Iven, H.4
-
53
-
-
0005454374
-
Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population
-
Spire-Vayron de la Moureyre C, Debuysere H, Mastain B, Vinner E, Marez D, Lo Guidice JM, Chevalier D, Brique S, Motte K, Colombel JF, Turck D, Noel C, Flipo RM, Pol A, Lhermitte M, Lafitte JJ, Libersa C, Broly F. Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population. Br J Pharmacol 1998; 125: 879-887
-
(1998)
Br J Pharmacol
, vol.125
, pp. 879-887
-
-
Spire-Vayron de la Moureyre, C.1
Debuysere, H.2
Mastain, B.3
Vinner, E.4
Marez, D.5
Lo Guidice, J.M.6
Chevalier, D.7
Brique, S.8
Motte, K.9
Colombel, J.F.10
Turck, D.11
Noel, C.12
Flipo, R.M.13
Pol, A.14
Lhermitte, M.15
Lafitte, J.J.16
Libersa, C.17
Broly, F.18
-
54
-
-
0035037703
-
Rational dosing of azathioprine and 6-mercaptopurine
-
Sandborn WJ. Rational dosing of azathioprine and 6-mercaptopurine. Gut 2001; 48: 591-592
-
(2001)
Gut
, vol.48
, pp. 591-592
-
-
Sandborn, W.J.1
-
55
-
-
4644241129
-
Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease
-
Winter J, Walker A, Shapiro D, Gaffney D, Spooner RJ, Mills PR. Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease. Aliment Pharmacol Ther 2004; 20: 593-599
-
(2004)
Aliment Pharmacol Ther
, vol.20
, pp. 593-599
-
-
Winter, J.1
Walker, A.2
Shapiro, D.3
Gaffney, D.4
Spooner, R.J.5
Mills, P.R.6
-
56
-
-
15444367938
-
ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression
-
Allorge D, Hamdan R, Broly F, Libersa C, Colombel JF. ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression. Gut 2005; 54: 565
-
(2005)
Gut
, vol.54
, pp. 565
-
-
Allorge, D.1
Hamdan, R.2
Broly, F.3
Libersa, C.4
Colombel, J.F.5
-
57
-
-
9244237558
-
Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine
-
Gearry RB, Roberts RL, Barclay ML, Kennedy MA. Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine. Pharmacogenetics 2004; 14: 779-781
-
(2004)
Pharmacogenetics
, vol.14
, pp. 779-781
-
-
Gearry, R.B.1
Roberts, R.L.2
Barclay, M.L.3
Kennedy, M.A.4
-
58
-
-
0346998117
-
Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy
-
Shastri S, Dubinsky MC, Fred Poordad F, Vasiliauskas EA, Geller SA. Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy. Arch Pathol Lab Med 2004; 128: 49-53
-
(2004)
Arch Pathol Lab Med
, vol.128
, pp. 49-53
-
-
Shastri, S.1
Dubinsky, M.C.2
Fred Poordad, F.3
Vasiliauskas, E.A.4
Geller, S.A.5
-
59
-
-
0043168014
-
6-thioguanine can cause serious liver injury in inflammatory bowel disease patients
-
Dubinsky MC, Vasiliauskas EA, Singh H, Abreu MT, Papadakis KA, Tran T, Martin P, Vierling JM, Geller SA, Targan SR, Poordad FF. 6-thioguanine can cause serious liver injury in inflammatory bowel disease patients. Gastroenterology 2003; 125: 298-303
-
(2003)
Gastroenterology
, vol.125
, pp. 298-303
-
-
Dubinsky, M.C.1
Vasiliauskas, E.A.2
Singh, H.3
Abreu, M.T.4
Papadakis, K.A.5
Tran, T.6
Martin, P.7
Vierling, J.M.8
Geller, S.A.9
Targan, S.R.10
Poordad, F.F.11
-
60
-
-
0030995879
-
Molecular mechanisms of genetic polymorphisms of drug metabolism
-
Meyer UA, Zanger UM. Molecular mechanisms of genetic polymorphisms of drug metabolism. Annu Rev Pharmacol Toxicol 1997; 37: 269-296
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 269-296
-
-
Meyer, U.A.1
Zanger, U.M.2
-
61
-
-
0035052559
-
Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms
-
Fretland AJ, Leff MA, Doll MA, Hein DW. Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms. Pharmacogenetics 2001; 11: 207-215
-
(2001)
Pharmacogenetics
, vol.11
, pp. 207-215
-
-
Fretland, A.J.1
Leff, M.A.2
Doll, M.A.3
Hein, D.W.4
-
62
-
-
0021813284
-
N-acetylation pharmacogenetics
-
Weber WW, Hein DW, N-acetylation pharmacogenetics. Pharmacol Rev 1985; 37: 25-79
-
(1985)
Pharmacol Rev
, vol.37
, pp. 25-79
-
-
Weber, W.W.1
Hein, D.W.2
-
63
-
-
0028831941
-
Nomenclature for N-acetyltransferases
-
Vatsis KP, Weber WW, Bell DA, Dupret JM, Evans DA, Grant DM, Hein DW, Lin HJ, Meyer UA, Relling MV. Nomenclature for N-acetyltransferases. Pharmacogenetics 1993; 5: 1-17
-
(1993)
Pharmacogenetics
, vol.5
, pp. 1-17
-
-
Vatsis, K.P.1
Weber, W.W.2
Bell, D.A.3
Dupret, J.M.4
Evans, D.A.5
Grant, D.M.6
Hein, D.W.7
Lin, H.J.8
Meyer, U.A.9
Relling, M.V.10
-
64
-
-
0033520939
-
Novel human N-acetyltransferase 2 alleles that differ in mechanism for slow acetylator phenotype
-
Leff MA, Fretland AJ, Doll MA, Hein DW. Novel human N-acetyltransferase 2 alleles that differ in mechanism for slow acetylator phenotype. J Biol Chem 1999; 274: 34519-34522
-
(1999)
J Biol Chem
, vol.274
, pp. 34519-34522
-
-
Leff, M.A.1
Fretland, A.J.2
Doll, M.A.3
Hein, D.W.4
-
65
-
-
0028270681
-
Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene
-
Lin HJ, Han CY, Lin BK, Hardy S. Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene. Pharmacogenetics 1994; 4: 125-134
-
(1994)
Pharmacogenetics
, vol.4
, pp. 125-134
-
-
Lin, H.J.1
Han, C.Y.2
Lin, B.K.3
Hardy, S.4
-
66
-
-
0034893017
-
Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1
-
Fretland AJ, Doll MA, Leff MA, Hein DW. Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1. Pharmacogenetics 2001; 11: 311-520
-
(2001)
Pharmacogenetics
, vol.11
, pp. 311-520
-
-
Fretland, A.J.1
Doll, M.A.2
Leff, M.A.3
Hein, D.W.4
-
67
-
-
0033960051
-
Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms
-
Hein DW, Doll MA, Fretland AJ, Leff MA, Webb SJ, Xiao GH, Devanaboyina US, Nangju NA, Feng Y. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol Biomarkers Prev 2000; 9: 29-42
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 29-42
-
-
Hein, D.W.1
Doll, M.A.2
Fretland, A.J.3
Leff, M.A.4
Webb, S.J.5
Xiao, G.H.6
Devanaboyina, U.S.7
Nangju, N.A.8
Feng, Y.9
-
68
-
-
0345240943
-
Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1)
-
Bruhn C, Brockmoller J, Cascorbi I, Roots I, Borchert HH. Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1). Biochem Pharmacol 1999; 58: 1759-1764
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 1759-1764
-
-
Bruhn, C.1
Brockmoller, J.2
Cascorbi, I.3
Roots, I.4
Borchert, H.H.5
-
69
-
-
7144226607
-
Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas
-
Lin HJ, Probst-Hensch NM, Hughes NC, Sakamoto GT, Louie AD, Kau IH, Lin BK, Lee DB, Lin J, Frankl HD, Lee ER, Hardy S, Grant DM, Haile RW. Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas. Pharmacogenetics 1998; 8: 269-281
-
(1998)
Pharmacogenetics
, vol.8
, pp. 269-281
-
-
Lin, H.J.1
Probst-Hensch, N.M.2
Hughes, N.C.3
Sakamoto, G.T.4
Louie, A.D.5
Kau, I.H.6
Lin, B.K.7
Lee, D.B.8
Lin, J.9
Frankl, H.D.10
Lee, E.R.11
Hardy, S.12
Grant, D.M.13
Haile, R.W.14
-
70
-
-
0015916139
-
Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype
-
Das KM, Eastwood MA, McManus JP, Sircus W. Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. N Engl J Med 1973; 289: 491-495
-
(1973)
N Engl J Med
, vol.289
, pp. 491-495
-
-
Das, K.M.1
Eastwood, M.A.2
McManus, J.P.3
Sircus, W.4
-
71
-
-
0037803498
-
Sulphasalazine-induced leucopenia in a patient with renal dysfunction
-
Teshima D, Hino B, Makino K, Yano T, Itoh Y, Joh Y, Iida M, Oishi R. Sulphasalazine-induced leucopenia in a patient with renal dysfunction. J Clin Pharm Ther 2003; 28: 239-242
-
(2003)
J Clin Pharm Ther
, vol.28
, pp. 239-242
-
-
Teshima, D.1
Hino, B.2
Makino, K.3
Yano, T.4
Itoh, Y.5
Joh, Y.6
Iida, M.7
Oishi, R.8
-
72
-
-
0037863063
-
Slow acetylator genotypes as a possible risk factor for infectious mononucleosis-like syndrome induced by salazosulfapyridine
-
Ohtani T, Hiroi A, Sakurane M, Furukawa F. Slow acetylator genotypes as a possible risk factor for infectious mononucleosis-like syndrome induced by salazosulfapyridine. Br J Dermatol 2003; 148: 1035-1039
-
(2003)
Br J Dermatol
, vol.148
, pp. 1035-1039
-
-
Ohtani, T.1
Hiroi, A.2
Sakurane, M.3
Furukawa, F.4
-
73
-
-
0036310989
-
N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis
-
Ricart E, Taylor WR, Loftus EV, O'Kane D, Weinshilboum RM, Tremaine WJ, Harmsen WS, Zinsmeister AR, Sandborn WJ. N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis. Am J Gastroenterol 2002; 97: 1763-1768
-
(2002)
Am J Gastroenterol
, vol.97
, pp. 1763-1768
-
-
Ricart, E.1
Taylor, W.R.2
Loftus, E.V.3
O'Kane, D.4
Weinshilboum, R.M.5
Tremaine, W.J.6
Harmsen, W.S.7
Zinsmeister, A.R.8
Sandborn, W.J.9
-
74
-
-
22944470530
-
Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis
-
Cronstein BN. Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacol Rev 2005; 57: 163-172
-
(2005)
Pharmacol Rev
, vol.57
, pp. 163-172
-
-
Cronstein, B.N.1
-
75
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJ, den Heijer M, Kluijtmans LA, van den Heuvel LP. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995; 10: 111-113
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
Boers, G.J.7
den Heijer, M.8
Kluijtmans, L.A.9
van den Heuvel, L.P.10
-
76
-
-
0034944211
-
Effect of folic or fohnic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: A forty-eight week, multicenter, randomized, double-blind, placebo-controlled study
-
van Ede AE, Laan RF, Rood MJ, Huizinga TW, van de Laar MA, van Denderen CJ, Westgeest TA, Romme TC, de Rooij DJ, Jacobs MJ, de Boo TM, van der Wilt GJ, Severens JL, Hartman M, Krabbe PF, Dijkmans BA, Breedveld FC, van de Putte LB. Effect of folic or fohnic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2001; 44: 1515-1524
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1515-1524
-
-
van Ede, A.E.1
Laan, R.F.2
Rood, M.J.3
Huizinga, T.W.4
van de Laar, M.A.5
van Denderen, C.J.6
Westgeest, T.A.7
Romme, T.C.8
de Rooij, D.J.9
Jacobs, M.J.10
de Boo, T.M.11
van der Wilt, G.J.12
Severens, J.L.13
Hartman, M.14
Krabbe, P.F.15
Dijkmans, B.A.16
Breedveld, F.C.17
van de Putte, L.B.18
-
77
-
-
0035157121
-
The C677T mutation in the methylenetetrahydrofolate reductase gene: A genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients
-
Van Ede AE, Laan RF, Blom HJ, Huizinga TW, Haagsma CJ, Giesendorf BA, De Boo TM, van de Putte LB. The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients. Arthritis Rheum 2001; 44: 2525-2530
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2525-2530
-
-
Van Ede, A.E.1
Laan, R.F.2
Blom, H.J.3
Huizinga, T.W.4
Haagsma, C.J.5
Giesendorf, B.A.6
De Boo, T.M.7
van de Putte, L.B.8
-
78
-
-
0035412398
-
Pharmacogenetics of methotrexate: Toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism
-
Ulrich CM, Yasui Y, Storb R, Schubert MM, Wagner JL, Bigler J, Ariail KS, Keener CL, Li S, Liu H, Farin FM, Potter JD. Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism. Blood 2001; 98: 231-234
-
(2001)
Blood
, vol.98
, pp. 231-234
-
-
Ulrich, C.M.1
Yasui, Y.2
Storb, R.3
Schubert, M.M.4
Wagner, J.L.5
Bigler, J.6
Ariail, K.S.7
Keener, C.L.8
Li, S.9
Liu, H.10
Farin, F.M.11
Potter, J.D.12
-
79
-
-
2142820811
-
Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia
-
Robien K, Schubert MM, Bruemmer B, Lloid ME, Potter JD, Ulrich CM. Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia. J Clin Oncol 2004; 22: 1268-1275
-
(2004)
J Clin Oncol
, vol.22
, pp. 1268-1275
-
-
Robien, K.1
Schubert, M.M.2
Bruemmer, B.3
Lloid, M.E.4
Potter, J.D.5
Ulrich, C.M.6
-
80
-
-
0033998678
-
MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF)
-
Toffoli G, Veronesi A, Boiocchi M, Crivellari D. MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF). Ann Oncol 2000; 11: 373-374
-
(2000)
Ann Oncol
, vol.11
, pp. 373-374
-
-
Toffoli, G.1
Veronesi, A.2
Boiocchi, M.3
Crivellari, D.4
-
81
-
-
0034771885
-
A novel single-nucleotide polymorphism in the 3′-untranslated region of the human dihydrofolate reductase gene with enhanced expression
-
Goto Y, Yue L, Yokoi A, Nishimura R, Uehara T, Koizumi S, Saikawa Y. A novel single-nucleotide polymorphism in the 3′-untranslated region of the human dihydrofolate reductase gene with enhanced expression. Clin Cancer Res 2001; 7: 1952-1956
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1952-1956
-
-
Goto, Y.1
Yue, L.2
Yokoi, A.3
Nishimura, R.4
Uehara, T.5
Koizumi, S.6
Saikawa, Y.7
-
82
-
-
4444376725
-
Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis
-
Dervieux T, Furst D, Lein DO, Capps R, Smith K, Walsh M, Kremer J. Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis. Arthritis Rheum 2004; 50: 2766-2774
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2766-2774
-
-
Dervieux, T.1
Furst, D.2
Lein, D.O.3
Capps, R.4
Smith, K.5
Walsh, M.6
Kremer, J.7
-
83
-
-
0036161216
-
A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease
-
Sandborn WJ, Feagan BG, Hanauer SB, Lochs H, Lofberg R, Modigliani R, Present DH, Rutgeerts P, Scholmerich J, Stange EF, Sutherland LR. A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease. Gastroenterology 2002; 122: 512-530
-
(2002)
Gastroenterology
, vol.122
, pp. 512-530
-
-
Sandborn, W.J.1
Feagan, B.G.2
Hanauer, S.B.3
Lochs, H.4
Lofberg, R.5
Modigliani, R.6
Present, D.H.7
Rutgeerts, P.8
Scholmerich, J.9
Stange, E.F.10
Sutherland, L.R.11
-
84
-
-
0034903792
-
The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study
-
Faubion WA Jr, Loftus EV Jr, Harmsen WS, Zinsmeister AR, Sandborn WJ. The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 2001; 121: 255-260
-
(2001)
Gastroenterology
, vol.121
, pp. 255-260
-
-
Faubion Jr., W.A.1
Loftus Jr., E.V.2
Harmsen, W.S.3
Zinsmeister, A.R.4
Sandborn, W.J.5
-
85
-
-
0028267896
-
Frequency of glucocorticoid resistance and dependency in Crohn's disease
-
Munkholm P, Langholz E, Davidsen M, Binder V. Frequency of glucocorticoid resistance and dependency in Crohn's disease. Gut 1994; 35: 360-362
-
(1994)
Gut
, vol.35
, pp. 360-362
-
-
Munkholm, P.1
Langholz, E.2
Davidsen, M.3
Binder, V.4
-
86
-
-
0028966791
-
Steroid dependency in Crohn's disease
-
Reinisch W, Gasche C, Wyatt J, Moser G, Lochs H, Vogelsang H, Gangl A. Steroid dependency in Crohn's disease. Lancet 1995; 345: 859
-
(1995)
Lancet
, vol.345
, pp. 859
-
-
Reinisch, W.1
Gasche, C.2
Wyatt, J.3
Moser, G.4
Lochs, H.5
Vogelsang, H.6
Gangl, A.7
-
87
-
-
0141619279
-
Glucocorticoid resistance in inflammatory bowel disease
-
Farrell RJ, Kelleher D. Glucocorticoid resistance in inflammatory bowel disease. J Endocrinol 2003; 178: 339-346
-
(2003)
J Endocrinol
, vol.178
, pp. 339-346
-
-
Farrell, R.J.1
Kelleher, D.2
-
88
-
-
0030026791
-
Review article: Refractory distal colitis - Explanations and options
-
Griffin MG, Miner PB. Review article: refractory distal colitis - explanations and options. Aliment Pharmacol Ther 1996; 10: 39-48
-
(1996)
Aliment Pharmacol Ther
, vol.10
, pp. 39-48
-
-
Griffin, M.G.1
Miner, P.B.2
-
89
-
-
0021881990
-
Primary cortisol resistance accompanied by a reduction in glucocorticoid receptors in two members of the same family
-
Iida S, Gomi M, Moriwaki K, Itoh Y, Hirobe K, Matsuzawa Y, Katagiri S, Yonezawa T, Tarui S. Primary cortisol resistance accompanied by a reduction in glucocorticoid receptors in two members of the same family. J Clin Endocrinol Metab 1985; 60: 967-971
-
(1985)
J Clin Endocrinol Metab
, vol.60
, pp. 967-971
-
-
Iida, S.1
Gomi, M.2
Moriwaki, K.3
Itoh, Y.4
Hirobe, K.5
Matsuzawa, Y.6
Katagiri, S.7
Yonezawa, T.8
Tarui, S.9
-
90
-
-
0034058875
-
Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis
-
Honda M, Orii F, Ayabe T, Imai S, Ashida T, Obara T, Kohgo Y. Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis. Gastroenterology 2000; 118: 859-866
-
(2000)
Gastroenterology
, vol.118
, pp. 859-866
-
-
Honda, M.1
Orii, F.2
Ayabe, T.3
Imai, S.4
Ashida, T.5
Obara, T.6
Kohgo, Y.7
-
91
-
-
0030026713
-
Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
-
Bamberger CM, Schulte HM, Chrousos GP. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr Rev 1996; 17: 245-261
-
(1996)
Endocr Rev
, vol.17
, pp. 245-261
-
-
Bamberger, C.M.1
Schulte, H.M.2
Chrousos, G.P.3
-
92
-
-
0033959944
-
High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy
-
Farrell RJ, Murphy A, Long A, Donnelly S, Cherikuri A, O'Toole D, Mahmud N, Keeling PW, Weir DG, Kelleher D. High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy. Gastroenterology 2000; 118: 279-288
-
(2000)
Gastroenterology
, vol.118
, pp. 279-288
-
-
Farrell, R.J.1
Murphy, A.2
Long, A.3
Donnelly, S.4
Cherikuri, A.5
O'Toole, D.6
Mahmud, N.7
Keeling, P.W.8
Weir, D.G.9
Kelleher, D.10
-
93
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmoller J, Johne A, Cascorbi I, Gerloff T, Roots I, Eichelbaum M, Brinkmann U. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97: 3473-3478
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
Brinkmann, U.11
-
94
-
-
8844229534
-
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
-
Potocnik U, Ferkolj I, Glavac D, Dean M. Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis. Genes Immun 2004; 5: 530-539
-
(2004)
Genes Immun
, vol.5
, pp. 530-539
-
-
Potocnik, U.1
Ferkolj, I.2
Glavac, D.3
Dean, M.4
-
95
-
-
1942540074
-
MDR1 mRNA expressions in peripheral blood mononuclear cells of patients with ulcerative colitis in relation to glucocorticoid administration
-
Hirano T, Onda K, Toma T, Miyaoka M, Moriyasu F, Oka K. MDR1 mRNA expressions in peripheral blood mononuclear cells of patients with ulcerative colitis in relation to glucocorticoid administration. J Clin Pharmacol 2004; 44: 481-486
-
(2004)
J Clin Pharmacol
, vol.44
, pp. 481-486
-
-
Hirano, T.1
Onda, K.2
Toma, T.3
Miyaoka, M.4
Moriyasu, F.5
Oka, K.6
-
96
-
-
9144224852
-
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease
-
Brant SR, Panhuysen CI, Nicolae D, Reddy DM, Bonen DK, Karaliukas R, Zhang L, Swanson E, Datta LW, Moran T, Ravenhill G, Duerr RH, Achkar JP, Karban AS, Cho JH. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am J Hum Genet 2003; 73: 1282-1292
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1282-1292
-
-
Brant, S.R.1
Panhuysen, C.I.2
Nicolae, D.3
Reddy, D.M.4
Bonen, D.K.5
Karaliukas, R.6
Zhang, L.7
Swanson, E.8
Datta, L.W.9
Moran, T.10
Ravenhill, G.11
Duerr, R.H.12
Achkar, J.P.13
Karban, A.S.14
Cho, J.H.15
-
97
-
-
14944341671
-
Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis
-
Ho GT, Nimmo ER, Tenesa A, Fennell J, Drummond H, Mowat C, Arnott ID, Satsangi J. Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis. Gastroenterology 2005; 128: 288-296
-
(2005)
Gastroenterology
, vol.128
, pp. 288-296
-
-
Ho, G.T.1
Nimmo, E.R.2
Tenesa, A.3
Fennell, J.4
Drummond, H.5
Mowat, C.6
Arnott, I.D.7
Satsangi, J.8
-
98
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease
-
Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, van Deventer SJ, Mayer L, Present DH, Braakman T, DeWoody KL, Schaible TF, Rutgeerts PJ. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997; 337: 1029-1035
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
van Deventer, S.J.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.J.9
-
99
-
-
0032833517
-
Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease
-
Rutgeerts P, D'Haens G, Targan S, Vasiliauskas E, Hanauer SB, Present DH, Mayer L, Van Hogezand RA, Braakman T, DeWoody KL, Schaible TF, Van Deventer SJ. Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease. Gastroenterology 1999; 117: 761-769
-
(1999)
Gastroenterology
, vol.117
, pp. 761-769
-
-
Rutgeerts, P.1
D'Haens, G.2
Targan, S.3
Vasiliauskas, E.4
Hanauer, S.B.5
Present, D.H.6
Mayer, L.7
Van Hogezand, R.A.8
Braakman, T.9
DeWoody, K.L.10
Schaible, T.F.11
Van Deventer, S.J.12
-
100
-
-
0033529049
-
Infliximab for the treatment of fistulas in patients with Crohn's disease
-
Present DH, Rutgeerts P, Targan S, Hanauer SB, Mayer L, van Hogezand RA, Podolsky DK, Sands BE, Braakman T, DeWoody KL, Schaible TF, van Deventer SJ. Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 1999; 340: 1398-1405
-
(1999)
N Engl J Med
, vol.340
, pp. 1398-1405
-
-
Present, D.H.1
Rutgeerts, P.2
Targan, S.3
Hanauer, S.B.4
Mayer, L.5
van Hogezand, R.A.6
Podolsky, D.K.7
Sands, B.E.8
Braakman, T.9
DeWoody, K.L.10
Schaible, T.F.11
van Deventer, S.J.12
-
101
-
-
19144369300
-
Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model
-
Shen C, Maerten P, Geboes K, Van Assche G, Rutgeerts P, Ceuppens JL. Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model, Clin Immunol 2005; 115: 250-259
-
(2005)
Clin Immunol
, vol.115
, pp. 250-259
-
-
Shen, C.1
Maerten, P.2
Geboes, K.3
Van Assche, G.4
Rutgeerts, P.5
Ceuppens, J.L.6
-
102
-
-
0038047689
-
Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease
-
Van den Brande JM, Braat H, van den Brink GR, Versteeg HH, Bauer CA, Hoedemaeker I, van Montfrans C, Hommes DW, Peppelenbosch MP, van Deventer SJ. Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease. Gastroenterology 2003; 124: 1774-1785
-
(2003)
Gastroenterology
, vol.124
, pp. 1774-1785
-
-
Van den Brande, J.M.1
Braat, H.2
van den Brink, G.R.3
Versteeg, H.H.4
Bauer, C.A.5
Hoedemaeker, I.6
van Montfrans, C.7
Hommes, D.W.8
Peppelenbosch, M.P.9
van Deventer, S.J.10
-
103
-
-
0036151047
-
Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease
-
ten Hove T, van Montfrans C, Peppelenbosch MP, van Deventer SJ. Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002; 50: 206-211
-
(2002)
Gut
, vol.50
, pp. 206-211
-
-
ten Hove, T.1
van Montfrans, C.2
Peppelenbosch, M.P.3
van Deventer, S.J.4
-
104
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O'Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411: 599-603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
Macry, J.17
Colombel, J.F.18
Sahbatou, M.19
Thomas, G.20
more..
-
105
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411: 603-606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nunez, G.16
Cho, J.H.17
-
106
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
-
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G. Nod2, a Nod1/ Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem 2001; 276: 4812-4818
-
(2001)
J Biol Chem
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.F.4
Yamaoka, S.5
Nunez, G.6
-
107
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, Crespo J, Fukase K, Inamura S, Kusumoto S, Hashimoto M, Foster SJ, Moran AP, Fernandez-Luna JL, Nunez G. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003; 278: 5509-5512
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
Crespo, J.6
Fukase, K.7
Inamura, S.8
Kusumoto, S.9
Hashimoto, M.10
Foster, S.J.11
Moran, A.P.12
Fernandez-Luna, J.L.13
Nunez, G.14
-
108
-
-
0037221395
-
Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan
-
Bonen DK, Ogura Y, Nicolae DL, Inohara N, Saab L, Tanabe T, Chen FF, Foster SJ, Duerr RH, Brant SR, Cho JH, Nunez G, Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan, Gastroenterology 2003; 124: 140-146
-
(2003)
Gastroenterology
, vol.124
, pp. 140-146
-
-
Bonen, D.K.1
Ogura, Y.2
Nicolae, D.L.3
Inohara, N.4
Saab, L.5
Tanabe, T.6
Chen, F.F.7
Foster, S.J.8
Duerr, R.H.9
Brant, S.R.10
Cho, J.H.11
Nunez, G.12
-
109
-
-
0036305537
-
NOD2/CARD15 does not influence response to infliximab in Crohn's disease
-
Vermeire S, Louis E, Rutgeerts P, De Vos M, Van Gossum A, Belaiche J, Pescatore P, Fiasse R, Pelckmans P, Vlietinck R, Merlin F, Zouali H, Thomas G, Colombel JF, Hugot JP. NOD2/CARD15 does not influence response to infliximab in Crohn's disease. Gastroenterology 2002; 123: 106-111
-
(2002)
Gastroenterology
, vol.123
, pp. 106-111
-
-
Vermeire, S.1
Louis, E.2
Rutgeerts, P.3
De Vos, M.4
Van Gossum, A.5
Belaiche, J.6
Pescatore, P.7
Fiasse, R.8
Pelckmans, P.9
Vlietinck, R.10
Merlin, F.11
Zouali, H.12
Thomas, G.13
Colombel, J.F.14
Hugot, J.P.15
-
110
-
-
18644366895
-
Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: An analysis in 534 patients from two multicenter, prospective GCP-level trials
-
Mascheretti S, Hampe J, Croucher PJ, Nikolaus S, Andus T, Schubert S, Olson A, Bao W, FoIsch UR, Schreiber S. Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials. Pharmacogenetics 2002; 12: 509-515
-
(2002)
Pharmacogenetics
, vol.12
, pp. 509-515
-
-
Mascheretti, S.1
Hampe, J.2
Croucher, P.J.3
Nikolaus, S.4
Andus, T.5
Schubert, S.6
Olson, A.7
Bao, W.8
Folsch, U.R.9
Schreiber, S.10
-
111
-
-
0036367145
-
Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab
-
Mascheretti S, Hampe J, Kuhbacher T, Herfarth H, Krawczak M, Folsch UR, Schreiber S. Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab. Pharmacogenomics J 2002; 2: 127-136
-
(2002)
Pharmacogenomics J
, vol.2
, pp. 127-136
-
-
Mascheretti, S.1
Hampe, J.2
Kuhbacher, T.3
Herfarth, H.4
Krawczak, M.5
Folsch, U.R.6
Schreiber, S.7
-
112
-
-
4043140020
-
Tumour necrosis factor-alpha receptor 1 and 2 polymorphisms in inflammatory bowel disease and their association with response to infliximab
-
Pierik M, Vermeire S, Steen KV, Joossens S, Claessens G, Vlietinck R, Rutgeerts P. Tumour necrosis factor-alpha receptor 1 and 2 polymorphisms in inflammatory bowel disease and their association with response to infliximab. Aliment Pharmacol Ther 2004; 20: 303-310
-
(2004)
Aliment Pharmacol Ther
, vol.20
, pp. 303-310
-
-
Pierik, M.1
Vermeire, S.2
Steen, K.V.3
Joossens, S.4
Claessens, G.5
Vlietinck, R.6
Rutgeerts, P.7
-
113
-
-
0035050836
-
ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease
-
Taylor KD, Plevy SE, Yang H, Landers CJ, Barry MJ, Rotter JI, Targan SR. ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease. Gastroenterology 2001; 120: 1347-1355
-
(2001)
Gastroenterology
, vol.120
, pp. 1347-1355
-
-
Taylor, K.D.1
Plevy, S.E.2
Yang, H.3
Landers, C.J.4
Barry, M.J.5
Rotter, J.I.6
Targan, S.R.7
-
114
-
-
0035988896
-
A positive response to infliximab in Crohn disease: Association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism
-
Louis E, Vermeire S, Rutgeerts P, De Vos M, Van Gossum A, Pescatore P, Fiasse R, Pelckmans P, Reynaert H, D'Haens G, Malaise M, Belaiche J. A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism. Scand J Gastroenterol 2002; 37: 818-824
-
(2002)
Scand J Gastroenterol
, vol.37
, pp. 818-824
-
-
Louis, E.1
Vermeire, S.2
Rutgeerts, P.3
De Vos, M.4
Van Gossum, A.5
Pescatore, P.6
Fiasse, R.7
Pelckmans, P.8
Reynaert, H.9
D'Haens, G.10
Malaise, M.11
Belaiche, J.12
-
115
-
-
26244456815
-
Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease
-
Hlavaty T, Pierik M, Henckaerts L, Ferrante M, Joossens S, van Schuerbeek N, Noman M, Rutgeerts P, Vermeire S. Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease. Aliment Pharmacol Ther 2005; 22: 613-626
-
(2005)
Aliment Pharmacol Ther
, vol.22
, pp. 613-626
-
-
Hlavaty, T.1
Pierik, M.2
Henckaerts, L.3
Ferrante, M.4
Joossens, S.5
van Schuerbeek, N.6
Noman, M.7
Rutgeerts, P.8
Vermeire, S.9
-
116
-
-
0642373290
-
Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma
-
Weng WK, Levy R. Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma. J Clin Oncol 2003; 21: 3940-3947
-
(2003)
J Clin Oncol
, vol.21
, pp. 3940-3947
-
-
Weng, W.K.1
Levy, R.2
-
117
-
-
0036464719
-
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene
-
Cartron G, Dacheux L, Salles G, Solal-Celigny P, Bardos P, Colombat P, Watier H. Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood 2002; 99: 754-758
-
(2002)
Blood
, vol.99
, pp. 754-758
-
-
Cartron, G.1
Dacheux, L.2
Salles, G.3
Solal-Celigny, P.4
Bardos, P.5
Colombat, P.6
Watier, H.7
-
118
-
-
12144287977
-
Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease
-
Louis E, El Ghoul Z, Vermeire S, Dall'Ozzo S, Rutgeerts P, Paintaud G, Belaiche J, De Vos M, Van Gossum A, Colombel JF, Watier H. Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease. Aliment Pharmacol Ther 2004; 19: 511-519
-
(2004)
Aliment Pharmacol Ther
, vol.19
, pp. 511-519
-
-
Louis, E.1
El Ghoul, Z.2
Vermeire, S.3
Dall'Ozzo, S.4
Rutgeerts, P.5
Paintaud, G.6
Belaiche, J.7
De Vos, M.8
Van Gossum, A.9
Colombel, J.F.10
Watier, H.11
|