-
1
-
-
0029134702
-
Azathioprine and 6-mercaptopurine in Crohn's disease. A meta-analysis
-
Pearson DC, May GR, Fick GH, Sutherland LR. Azathioprine and 6-mercaptopurine in Crohn's disease. A meta-analysis. Ann Intern Med 1995; 123:132-142.
-
(1995)
Ann Intern Med
, vol.123
, pp. 132-142
-
-
Pearson, D.C.1
May, G.R.2
Fick, G.H.3
Sutherland, L.R.4
-
2
-
-
0029923360
-
A review of immune modifier therapy for inflammatory bowel disease: Azathioprine, 6-mercaptopurine, cyclosporine and methotrexate
-
Sandborn WJ. A review of immune modifier therapy for inflammatory bowel disease: azathioprine, 6-mercaptopurine, cyclosporine and methotrexate. Am J Gastroenterol 1996; 91:423-433.
-
(1996)
Am J Gastroenterol
, vol.91
, pp. 423-433
-
-
Sandborn, W.J.1
-
3
-
-
0025330168
-
The therapeutic efficacy of 6-mercaptopurine in refractory ulcerative colitis
-
Adler DJ, Korelitz BI. The therapeutic efficacy of 6-mercaptopurine in refractory ulcerative colitis. Am J Gastroenterol 1990; 85:717-722.
-
(1990)
Am J Gastroenterol
, vol.85
, pp. 717-722
-
-
Adler, D.J.1
Korelitz, B.I.2
-
4
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 1992; 43:329-339.
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
5
-
-
0030896836
-
Management of Crohn's disease in adults
-
Hanauer SB, Meyers SM. Management of Crohn's disease in adults. Am J Gastroenterol 1997; 92:559-566.
-
(1997)
Am J Gastroenterol
, vol.92
, pp. 559-566
-
-
Hanauer, S.B.1
Meyers, S.M.2
-
6
-
-
0028790186
-
A controlled double blind study of azathioprine in the management of Crohn's disease
-
Candy S, Wright J, Gerber M, Adams G, Gerig M, Goodman R. A controlled double blind study of azathioprine in the management of Crohn's disease. Gut 1995; 37:674-678.
-
(1995)
Gut
, vol.37
, pp. 674-678
-
-
Candy, S.1
Wright, J.2
Gerber, M.3
Adams, G.4
Gerig, M.5
Goodman, R.6
-
7
-
-
0018888679
-
Treatment of Crohn's disease with 6-mercaptopurine. A long-term randomised double-blind study
-
Present DH, Korelitz BI, Wisch N, Glass JL, Sachar DB, Pasternack BS. Treatment of Crohn's disease with 6-mercaptopurine. A long-term randomised double-blind study. N Engl J Med 1980; 302:981-987.
-
(1980)
N Engl J Med
, vol.302
, pp. 981-987
-
-
Present, D.H.1
Korelitz, B.I.2
Wisch, N.3
Glass, J.L.4
Sachar, D.B.5
Pasternack, B.S.6
-
8
-
-
0035037703
-
Rational dosing of azathioprine and 6-mercaptopurine
-
Sandborn WJ. Rational dosing of azathioprine and 6-mercaptopurine. Gut 2001; 48:591-592.
-
(2001)
Gut
, vol.48
, pp. 591-592
-
-
Sandborn, W.J.1
-
9
-
-
0029794073
-
6-Mercaptopurine metabolism in Crohn's disease: Correlation with efficacy and toxicity
-
Cuffari C, Theoret Y, Latour S, Seidman G. 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity. Gut 1996; 39:401-406.
-
(1996)
Gut
, vol.39
, pp. 401-406
-
-
Cuffari, C.1
Theoret, Y.2
Latour, S.3
Seidman, G.4
-
10
-
-
0034067784
-
Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
-
Dubinsky MC, Lamothe S, Yang HY, Targan SR, Sinnett D, Théoret J, Seidman EG. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000; 118:705-713.
-
(2000)
Gastroenterology
, vol.118
, pp. 705-713
-
-
Dubinsky, M.C.1
Lamothe, S.2
Yang, H.Y.3
Targan, S.R.4
Sinnett, D.5
Théoret, J.6
Seidman, E.G.7
-
11
-
-
0034771188
-
Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
-
Lowry PW, Franklin CL, Weaver AL, Pike MG, Mays DC, Tremaine WJ, et al. Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut 2001; 49:665-670.
-
(2001)
Gut
, vol.49
, pp. 665-670
-
-
Lowry, P.W.1
Franklin, C.L.2
Weaver, A.L.3
Pike, M.G.4
Mays, D.C.5
Tremaine, W.J.6
-
12
-
-
0035134907
-
Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease
-
Belaiche J, Desager JP, Horsmans Y, Louis E. Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease. Scand J Gastroenterol 2001; 36:71-76.
-
(2001)
Scand J Gastroenterol
, vol.36
, pp. 71-76
-
-
Belaiche, J.1
Desager, J.P.2
Horsmans, Y.3
Louis, E.4
-
13
-
-
0035037706
-
Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease
-
Cuffari C, Hunt S, Bayless T. Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease. Gut 2001; 48:642-646.
-
(2001)
Gut
, vol.48
, pp. 642-646
-
-
Cuffari, C.1
Hunt, S.2
Bayless, T.3
-
14
-
-
0031680256
-
Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease
-
Kirschner BS. Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease. Gastroenterology 1998; 115:813-821.
-
(1998)
Gastroenterology
, vol.115
, pp. 813-821
-
-
Kirschner, B.S.1
-
15
-
-
0024457688
-
6-Mercaptopurine in the management of inflammatory bowel disease: Short-and long-term toxicity
-
Present DH, Meltzer SJ, Krumholz MP, Wolke A, Koerelitz Bl. 6-Mercaptopurine in the management of inflammatory bowel disease: short-and long-term toxicity. Ann Intern Med 1989; 111:641-649.
-
(1989)
Ann Intern Med
, vol.111
, pp. 641-649
-
-
Present, D.H.1
Meltzer, S.J.2
Krumholz, M.P.3
Wolke, A.4
Koerelitz, Bl.5
-
16
-
-
0027164795
-
Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 Years of experience
-
Connell WR, Kamm MA, Ritchie JK, Lennard-Jones JE. Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience. Gut 1993; 34:1081-1085.
-
(1993)
Gut
, vol.34
, pp. 1081-1085
-
-
Connell, W.R.1
Kamm, M.A.2
Ritchie, J.K.3
Lennard-Jones, J.E.4
-
17
-
-
0034528822
-
The use of 6-mercaptopurine in patients with inflammatory bowel disease after failure of azathioprine
-
Boulton-Jones JR, Pritchard K, Mahmoud AA. The use of 6-mercaptopurine in patients with inflammatory bowel disease after failure of azathioprine. Aliment Pharmacol Ther 2000; 14:1561-1565.
-
(2000)
Aliment Pharmacol Ther
, vol.14
, pp. 1561-1565
-
-
Boulton-Jones, J.R.1
Pritchard, K.2
Mahmoud, A.A.3
-
18
-
-
0036180977
-
Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity
-
McGovern DP, Travis SPL, Duley J, el Shobowale-Bakre M, Dalton HR. Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity. Gastroenterology 2002; 122: 838-839.
-
(2002)
Gastroenterology
, vol.122
, pp. 838-839
-
-
McGovern, D.P.1
Travis, S.P.L.2
Duley, J.3
El Shobowale-Bakre, M.4
Dalton, H.R.5
-
19
-
-
12644291917
-
Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms
-
Otterness D, Szumlanski C, Lennard L, Klemetsdal B, Aarbakke J, ParkHah JO, et al. Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms. Clin Pharmacol Ther 1997; 62:60-73.
-
(1997)
Clin Pharmacol Ther
, vol.62
, pp. 60-73
-
-
Otterness, D.1
Szumlanski, C.2
Lennard, L.3
Klemetsdal, B.4
Aarbakke, J.5
Parkhah, J.O.6
-
20
-
-
0036076821
-
TPMT in the treatment of Crohn's disease with azathioprine
-
Lennard L. TPMT in the treatment of Crohn's disease with azathioprine. Gut 2002; 51:143-146.
-
(2002)
Gut
, vol.51
, pp. 143-146
-
-
Lennard, L.1
-
21
-
-
0031663491
-
Clinical implications of thiopurine methyltransferase-optimization of drug dosage and potential drug interactions
-
Lennard L. Clinical implications of thiopurine methyltransferase- optimization of drug dosage and potential drug interactions. Ther Drug Monit 1998; 20:527-531.
-
(1998)
Ther Drug Monit
, vol.20
, pp. 527-531
-
-
Lennard, L.1
-
22
-
-
2542639314
-
Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: Implications for therapy
-
Derijks LJJ, Gilissen LPL, Engels LGJB, Bos LP, Bus PJ, Lohman JJHM, et al. Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy. Ther Drug Monit; 26:311-318.
-
Ther Drug Monit
, vol.26
, pp. 311-318
-
-
Derijks, L.J.J.1
Gilissen, L.P.L.2
Engels, L.G.J.B.3
Bos, L.P.4
Bus, P.J.5
Lohman, J.J.H.M.6
-
23
-
-
0026465403
-
High performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: Quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-mercaptopurine metabolites in a single sample
-
Lennard L, Singleton HJ. High performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-mercaptopurine metabolites in a single sample. J Chromatogr 1992; 583:83-90.
-
(1992)
J Chromatogr
, vol.583
, pp. 83-90
-
-
Lennard, L.1
Singleton, H.J.2
-
24
-
-
0008690916
-
Cortisone in ulcerative colitis: Final report on a therapeutic trial
-
Truelove SC, Wilts LJ. Cortisone in ulcerative colitis: final report on a therapeutic trial. BMJ 1955; 4947:1041-1048.
-
(1955)
BMJ
, vol.4947
, pp. 1041-1048
-
-
Truelove, S.C.1
Wilts, L.J.2
-
25
-
-
0037250161
-
6-Thioguanine seems promising in azathioprine-or 6-mercaptopurine- intolerant inflammatory bowel disease patients: A short-term safety assessment
-
Derijks LJJ, De Jong DJ, Gilissen LPL, Engels LGJB, Hooymans PM, Jansen JBMJ, Mulder CJJ. 6-Thioguanine seems promising in azathioprine-or 6-mercaptopurine-intolerant inflammatory bowel disease patients: a short-term safety assessment. Eur J Gastroenterol Hepatol 2003; 15:63-67.
-
(2003)
Eur J Gastroenterol Hepatol
, vol.15
, pp. 63-67
-
-
Derijks, L.J.J.1
De Jong, D.J.2
Gilissen, L.P.L.3
Engels, L.G.J.B.4
Hooymans, P.M.5
Jansen, J.B.M.J.6
Mulder, C.J.J.7
-
26
-
-
0036202803
-
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
-
Dubinsky MC, Huiying Y, Hassard PV, Seidman EG, Kam LY, Abreu MT, et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology 2002; 122:904-915.
-
(2002)
Gastroenterology
, vol.122
, pp. 904-915
-
-
Dubinsky, M.C.1
Huiying, Y.2
Hassard, P.V.3
Seidman, E.G.4
Kam, L.Y.5
Abreu, M.T.6
-
27
-
-
0034891450
-
An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy
-
Dubinsky MC, Hassard PV, Seidman EG, Kam LY, Abreu MT, Targan SR, Vasiliauskas EA. An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy. Inflamm Bowel Dis 2001; 7:181-189.
-
(2001)
Inflamm Bowel Dis
, vol.7
, pp. 181-189
-
-
Dubinsky, M.C.1
Hassard, P.V.2
Seidman, E.G.3
Kam, L.Y.4
Abreu, M.T.5
Targan, S.R.6
Vasiliauskas, E.A.7
-
28
-
-
0038805258
-
Thioguanine: A potential alternative thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine
-
Dubinsky MC, Feldman EJ, Abreu MT, Targan SR, Vasiliauskas EA. Thioguanine: a potential alternative thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. Am J Gastroenterol 2003; 98: 1058-1063.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 1058-1063
-
-
Dubinsky, M.C.1
Feldman, E.J.2
Abreu, M.T.3
Targan, S.R.4
Vasiliauskas, E.A.5
-
29
-
-
0043168014
-
6-Thioguanine can cause serious liver injury in inflammatory bowel disease patients
-
Dubinsky MC, Vasiliauskas EA, Singh H, Abreu MT, Papadakis KA, Tan T, Martin P, et al. 6-Thioguanine can cause serious liver injury in inflammatory bowel disease patients. Gastroenterology 2003; 125: 298-303.
-
(2003)
Gastroenterology
, vol.125
, pp. 298-303
-
-
Dubinsky, M.C.1
Vasiliauskas, E.A.2
Singh, H.3
Abreu, M.T.4
Papadakis, K.A.5
Tan, T.6
Martin, P.7
-
30
-
-
0026007703
-
Nodular regenerative hyperplasia of the liver: An important cause of portal hypertension in non-cirrhotic patients
-
Naber AH, Van Haelst U, Yap SH. Nodular regenerative hyperplasia of the liver: an important cause of portal hypertension in non-cirrhotic patients. J Hepatol 1991; 12:94-99.
-
(1991)
J Hepatol
, vol.12
, pp. 94-99
-
-
Naber, A.H.1
Van Haelst, U.2
Yap, S.H.3
-
31
-
-
0029932363
-
Toxicity of azathioprine and monocrolatine in murine sinusoidal endothelial cells and hepatocytes: The role of glutathione and relevance to hepatic venoocclusive disease
-
Deleve LD, Wang X, Kuhlenkamp JF, Kaplowitz N. Toxicity of azathioprine and monocrolatine in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease. Hepatology 1996; 23:589-599.
-
(1996)
Hepatology
, vol.23
, pp. 589-599
-
-
Deleve, L.D.1
Wang, X.2
Kuhlenkamp, J.F.3
Kaplowitz, N.4
-
32
-
-
3142655080
-
Maintenance treatment with 6-thioguanine over one year in azathioprine or 6-mercaptopurine intolerant IBD patients
-
De Jong DJ, Derijks LJJ, Gilissen LPL, Engels LGJB, De Boer SY, Hooymans PM, et al. Maintenance treatment with 6-thioguanine over one year in azathioprine or 6-mercaptopurine intolerant IBD patients [Abstract]. Gut 2003; 52 (suppl VI):A58.
-
(2003)
Gut
, vol.52
, Issue.6 SUPPL.
-
-
De Jong, D.J.1
Derijks, L.J.J.2
Gilissen, L.P.L.3
Engels, L.G.J.B.4
De Boer, S.Y.5
Hooymans, P.M.6
-
33
-
-
0003374822
-
Oral 6-thioguanine causes late onset splenomegaly and portal hypertension in a subset of children with acute lymphoblastic leukemia
-
Stork LC, Broxson EH, Sather H. Oral 6-thioguanine causes late onset splenomegaly and portal hypertension in a subset of children with acute lymphoblastic leukemia [Abstract]. Gastroenterology 2002; 122:T833.
-
(2002)
Gastroenterology
, vol.122
-
-
Stork, L.C.1
Broxson, E.H.2
Sather, H.3
-
34
-
-
0036668038
-
Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: Impact of thiopurine S-methyltransferase polymorphism
-
Schwab M, Schaffeler E, Marx C, Fischer C, Lang T, Behren C, et al. Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism. Pharmacogenetics 2002; 12:429-436.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 429-436
-
-
Schwab, M.1
Schaffeler, E.2
Marx, C.3
Fischer, C.4
Lang, T.5
Behren, C.6
-
35
-
-
0037214334
-
Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine
-
Kaskas BA, Louis E, Hindorf U, Schaeffeler E, Deflandre J, Graepler F, et al. Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine. Gut 2003; 52:140-142.
-
(2003)
Gut
, vol.52
, pp. 140-142
-
-
Kaskas, B.A.1
Louis, E.2
Hindorf, U.3
Schaeffeler, E.4
Deflandre, J.5
Graepler, F.6
-
36
-
-
26344436017
-
No predictive value of thiopurine S-methyltransferase genotyping for myelosuppression or hepatotoxicity in inflammatory bowel disease patients established on azathioprine
-
Derijks LJJ, Curvers WL, Hooymans PM, Van Deventer SJH, Hommes DW. No predictive value of thiopurine S-methyltransferase genotyping for myelosuppression or hepatotoxicity in inflammatory bowel disease patients established on azathioprine [Abstract]. Gut 2003; 52 (suppl VI): A58.
-
(2003)
Gut
, vol.52
, Issue.6 SUPPL.
-
-
Derijks, L.J.J.1
Curvers, W.L.2
Hooymans, P.M.3
Van Deventer, S.J.H.4
Hommes, D.W.5
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