메뉴 건너뛰기




Volumn 342, Issue 22, 2000, Pages 1627-1632

A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE; PLACEBO; PREDNISONE;

EID: 0034214336     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200006013422202     Document Type: Article
Times cited : (715)

References (40)
  • 1
    • 0029114193 scopus 로고
    • Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease
    • Sartor RB. Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease. Gastroenterol Clin North Am 1995;24: 475-507.
    • (1995) Gastroenterol Clin North Am , vol.24 , pp. 475-507
    • Sartor, R.B.1
  • 2
    • 0029813752 scopus 로고    scopus 로고
    • Absence of skin sensitivity to oxides of aluminium, silicon, titanium or zirconium in patients with Crohn's disease
    • Lee JC, Halpern S, Lowe DG, Forbes A, Lennard-Jones JE. Absence of skin sensitivity to oxides of aluminium, silicon, titanium or zirconium in patients with Crohn's disease. Gut 1996;39:231-3.
    • (1996) Gut , vol.39 , pp. 231-233
    • Lee, J.C.1    Halpern, S.2    Lowe, D.G.3    Forbes, A.4    Lennard-Jones, J.E.5
  • 3
    • 0030885723 scopus 로고    scopus 로고
    • A case-control study of measles vaccination and inflammatory bowel disease
    • Feeney M, Ciegg A, Winwood P, Snook J. A case-control study of measles vaccination and inflammatory bowel disease. Lancet 1997;350:764-6.
    • (1997) Lancet , vol.350 , pp. 764-766
    • Feeney, M.1    Ciegg, A.2    Winwood, P.3    Snook, J.4
  • 4
    • 0030059771 scopus 로고    scopus 로고
    • Absence of measles viral genomic sequence in intestinal tissues from Crohn's disease by nested polymerase chain reaction
    • Haga Y, Funakoshi O, Kuroe K, et al. Absence of measles viral genomic sequence in intestinal tissues from Crohn's disease by nested polymerase chain reaction. Gut 1996;38:211-5.
    • (1996) Gut , vol.38 , pp. 211-215
    • Haga, Y.1    Funakoshi, O.2    Kuroe, K.3
  • 5
    • 0018290191 scopus 로고
    • National Cooperative Crohn's Disease Study: Results of drug treatment
    • Summers RW, Switz DM, Sessions JT Jr, et al. National Cooperative Crohn's Disease Study: results of drug treatment. Gastroenterology 1979; 77:847-69.
    • (1979) Gastroenterology , vol.77 , pp. 847-869
    • Summers, R.W.1    Switz, D.M.2    Sessions J.T., Jr.3
  • 6
    • 0021358010 scopus 로고
    • European Cooperative Crohn's Disease Study (ECCDS): Results of drug treatment
    • Malchow H, Ewe K, Brandes JW, et al. European Cooperative Crohn's Disease Study (ECCDS): results of drug treatment. Gastroenterology 1984;86:249-66.
    • (1984) Gastroenterology , vol.86 , pp. 249-266
    • Malchow, H.1    Ewe, K.2    Brandes, J.W.3
  • 7
    • 0027997229 scopus 로고
    • A comparison of budesonide with prednisolone for active Crohn's disease
    • Rutgeerts P, Löfberg R, Malchow H, et al. A comparison of budesonide with prednisolone for active Crohn's disease. N Engl J Med 1994;331:842-5.
    • (1994) N Engl J Med , vol.331 , pp. 842-845
    • Rutgeerts, P.1    Löfberg, R.2    Malchow, H.3
  • 9
    • 0024569907 scopus 로고
    • Steroid-related osteonecrosis in inflammatory bowel disease
    • Vakil N, Sparberg M. Steroid-related osteonecrosis in inflammatory bowel disease. Gastroenterology 1989;96:62-7.
    • (1989) Gastroenterology , vol.96 , pp. 62-67
    • Vakil, N.1    Sparberg, M.2
  • 10
  • 12
    • 0018117298 scopus 로고
    • Double-blind withdrawal trial of azathioprine as maintenance treatment for Crohn's disease
    • O'Donoghue DP, Dawson AM, Powell-Tuck J, Bown RL, Lennard-Jones JE. Double-blind withdrawal trial of azathioprine as maintenance treatment for Crohn's disease. Lancet 1978;2:955-7.
    • (1978) Lancet , vol.2 , pp. 955-957
    • O'Donoghue, D.P.1    Dawson, A.M.2    Powell-Tuck, J.3    Bown, R.L.4    Lennard-Jones, J.E.5
  • 13
    • 0028790186 scopus 로고
    • A controlled double blind study of azathioprine in the management of Crohn's disease
    • Candy S, Wright J, Gerber M, Adams G, Gerig M, Goodman R. A controlled double blind study of azathioprine in the management of Crohn's disease. Gut 1995;37:674-8.
    • (1995) Gut , vol.37 , pp. 674-678
    • Candy, S.1    Wright, J.2    Gerber, M.3    Adams, G.4    Gerig, M.5    Goodman, R.6
  • 14
    • 0030611582 scopus 로고    scopus 로고
    • Long-term treatment of destructive rheumatoid arthritis with methotrexate
    • Rau R, Schleusser B, Herborn G, Karger T. Long-term treatment of destructive rheumatoid arthritis with methotrexate. J Rheumatol 1997;24: 1881-9.
    • (1997) J Rheumatol , vol.24 , pp. 1881-1889
    • Rau, R.1    Schleusser, B.2    Herborn, G.3    Karger, T.4
  • 15
    • 0029566876 scopus 로고
    • Comparison of azathioprine, methotrexate, and the combination of the two in the treatment of rheumatoid arthritis: A forty-eight-week controlled clinical trial with radiologic outcome assessment
    • Willkens RF, Sharp JT, Stablein D, Marks C, Wortmann R. Comparison of azathioprine, methotrexate, and the combination of the two in the treatment of rheumatoid arthritis: a forty-eight-week controlled clinical trial with radiologic outcome assessment. Arthritis Rheum 1995;38:1799-806.
    • (1995) Arthritis Rheum , vol.38 , pp. 1799-1806
    • Willkens, R.F.1    Sharp, J.T.2    Stablein, D.3    Marks, C.4    Wortmann, R.5
  • 16
    • 0021923633 scopus 로고
    • Efficacy of low-dose methotrexate in rheumatoid arthritis
    • Weinblatt ME, Coblyn JS, Fox DA, et al. Efficacy of low-dose methotrexate in rheumatoid arthritis. N Engl J Med 1985;312:818-22.
    • (1985) N Engl J Med , vol.312 , pp. 818-822
    • Weinblatt, M.E.1    Coblyn, J.S.2    Fox, D.A.3
  • 17
    • 0028899859 scopus 로고
    • Methotrexate for the treatment of Crohn's disease
    • Feagan BG, Rochon J, Fedorak RN, et al. Methotrexate for the treatment of Crohn's disease. N Engl J Med 1995;332:292-7.
    • (1995) N Engl J Med , vol.332 , pp. 292-297
    • Feagan, B.G.1    Rochon, J.2    Fedorak, R.N.3
  • 18
    • 0029916174 scopus 로고    scopus 로고
    • Significant changes in serum AST across hepatic histological biopsy grades: Prospective analysis of 3 cohorts receiving methotrexate therapy for rheumatoid arthritis
    • Kremer JM, Furst DE, Weinblatt ME, Blotner SD. Significant changes in serum AST across hepatic histological biopsy grades: prospective analysis of 3 cohorts receiving methotrexate therapy for rheumatoid arthritis. J Rheumatol 1996;23:459-61.
    • (1996) J Rheumatol , vol.23 , pp. 459-461
    • Kremer, J.M.1    Furst, D.E.2    Weinblatt, M.E.3    Blotner, S.D.4
  • 19
    • 0030705165 scopus 로고    scopus 로고
    • Methotrexate hepatotoxicity
    • West SG. Methotrexate hepatotoxicity. Rheum Dis Clin North Am 1997;23:883-915.
    • (1997) Rheum Dis Clin North Am , vol.23 , pp. 883-915
    • West, S.G.1
  • 20
    • 0017227303 scopus 로고
    • Development of a Crohn's disease activity index: National Cooperative Crohn's Disease Study
    • Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohn's disease activity index: National Cooperative Crohn's Disease Study. Gastroenterology 1976;70:439-44.
    • (1976) Gastroenterology , vol.70 , pp. 439-444
    • Best, W.R.1    Becktel, J.M.2    Singleton, J.W.3    Kern F., Jr.4
  • 22
    • 0024517127 scopus 로고
    • Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease
    • Kozarek RA, Patterson DJ, Gelfand MD, Botoman VA, Ball TJ, Wilske KR. Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease. Ann Intern Med 1989;110:353-6.
    • (1989) Ann Intern Med , vol.110 , pp. 353-356
    • Kozarek, R.A.1    Patterson, D.J.2    Gelfand, M.D.3    Botoman, V.A.4    Ball, T.J.5    Wilske, K.R.6
  • 23
    • 0028267896 scopus 로고
    • Frequency of glucocorticoid resistance and dependency in Crohn's disease
    • Munkholm P, Langholz E, Davidsen M, Binder V. Frequency of glucocorticoid resistance and dependency in Crohn's disease. Gut 1994;35: 360-2.
    • (1994) Gut , vol.35 , pp. 360-362
    • Munkholm, P.1    Langholz, E.2    Davidsen, M.3    Binder, V.4
  • 24
    • 0030045968 scopus 로고    scopus 로고
    • Oral budesonide as maintenance treatment for Crohn's disease: A placebo-controlled, dose-ranging study
    • Greenberg GR, Feagan BG, Martin F, et al. Oral budesonide as maintenance treatment for Crohn's disease: a placebo-controlled, dose-ranging study. Gastroenterology 1996;110:45-51.
    • (1996) Gastroenterology , vol.110 , pp. 45-51
    • Greenberg, G.R.1    Feagan, B.G.2    Martin, F.3
  • 25
    • 8944242602 scopus 로고    scopus 로고
    • Budesonide prolongs time to relapse in ileal and ileocaecal Crohn's disease: A placebo controlled one year study
    • Löfberg R, Rutgeerts P, Malchow H, et al. Budesonide prolongs time to relapse in ileal and ileocaecal Crohn's disease: a placebo controlled one year study. Gut 1996;39:82-6.
    • (1996) Gut , vol.39 , pp. 82-86
    • Löfberg, R.1    Rutgeerts, P.2    Malchow, H.3
  • 26
    • 0029100737 scopus 로고
    • Methotrexate for Crohn's disease
    • Methotrexate for Crohn's disease. N Engl J Med 1995;333:600-1.
    • (1995) N Engl J Med , vol.333 , pp. 600-601
  • 27
    • 0024457688 scopus 로고
    • 6-Mercaptopurine in the management of inflammatory bowel disease: Short-and long-term toxicity
    • Present DH, Meltzer SJ, Krumholz MP, Wolke A, Korelitz BI. 6-Mercaptopurine in the management of inflammatory bowel disease: short-and long-term toxicity. Ann Intern Med 1989;111:641-9.
    • (1989) Ann Intern Med , vol.111 , pp. 641-649
    • Present, D.H.1    Meltzer, S.J.2    Krumholz, M.P.3    Wolke, A.4    Korelitz, B.I.5
  • 28
    • 0025089325 scopus 로고
    • Long-term 6-mercaptopurine treatment in adolescents with Crohn's disease
    • Markowitz J, Rosa J, Grancher K, Aiges H, Daum F. Long-term 6-mercaptopurine treatment in adolescents with Crohn's disease. Gastroenterology 1990;99:1347-51.
    • (1990) Gastroenterology , vol.99 , pp. 1347-1351
    • Markowitz, J.1    Rosa, J.2    Grancher, K.3    Aiges, H.4    Daum, F.5
  • 29
    • 0032981451 scopus 로고    scopus 로고
    • Trends in the use of disease modifying antirheumatic medications in rheumatoid arthritis, 1980-1995: Results from the National Ambulatory Medical Care Surveys
    • Ward MM. Trends in the use of disease modifying antirheumatic medications in rheumatoid arthritis, 1980-1995: results from the National Ambulatory Medical Care Surveys. J Rheumatol 1999;26:546-50.
    • (1999) J Rheumatol , vol.26 , pp. 546-550
    • Ward, M.M.1
  • 30
    • 0031798177 scopus 로고    scopus 로고
    • How Canadian and US rheumatologists treat moderate or aggressive rheumatoid arthritis: A survey
    • Maetzel A, Bombardier C, Strand V, Tugwell P, Wells G. How Canadian and US rheumatologists treat moderate or aggressive rheumatoid arthritis: a survey. J Rheumatol 1998;25:2331-8.
    • (1998) J Rheumatol , vol.25 , pp. 2331-2338
    • Maetzel, A.1    Bombardier, C.2    Strand, V.3    Tugwell, P.4    Wells, G.5
  • 31
    • 0033432652 scopus 로고    scopus 로고
    • Current treatment by United States and Canadian pediatric rheumatologists
    • Cron RQ, Sharma S, Sherry DD. Current treatment by United States and Canadian pediatric rheumatologists. J Rheumatol 1999;26:2036-8.
    • (1999) J Rheumatol , vol.26 , pp. 2036-2038
    • Cron, R.Q.1    Sharma, S.2    Sherry, D.D.3
  • 32
    • 0029995133 scopus 로고    scopus 로고
    • Combination treatment of rheumatoid arthritis using azathioprine and methotrexate: A 48 week controlled clinical trial
    • Willkens RF, Stablein D. Combination treatment of rheumatoid arthritis using azathioprine and methotrexate: a 48 week controlled clinical trial. J Rheumatol Suppl 1996;44:64-8.
    • (1996) J Rheumatol Suppl , vol.44 , pp. 64-68
    • Willkens, R.F.1    Stablein, D.2
  • 34
    • 0028965107 scopus 로고
    • The cost-effectiveness of liver biopsy in rheumatoid arthritis patients treated with methotrexate
    • Bergquist SR, Felson DT, Prashker MJ, Freedberg KA. The cost-effectiveness of liver biopsy in rheumatoid arthritis patients treated with methotrexate. Arthritis Rheum 1995;38:326-33.
    • (1995) Arthritis Rheum , vol.38 , pp. 326-333
    • Bergquist, S.R.1    Felson, D.T.2    Prashker, M.J.3    Freedberg, K.A.4
  • 35
    • 0029130827 scopus 로고
    • Usefulness of the American College of Rheumatology recommendations for liver biopsy in methotrexate-treated rheumatoid arthritis patients
    • Erickson AR, Reddy V, Vogelgesang SA, West SG. Usefulness of the American College of Rheumatology recommendations for liver biopsy in methotrexate-treated rheumatoid arthritis patients. Arthritis Rheum 1995; 38:1115-9.
    • (1995) Arthritis Rheum , vol.38 , pp. 1115-1119
    • Erickson, A.R.1    Reddy, V.2    Vogelgesang, S.A.3    West, S.G.4
  • 36
    • 0028215036 scopus 로고
    • Methotrexate for rheumatoid arthritis: Suggested guidelines for monitoring liver toxicity
    • Kremer JM, Alarcon GS, Lightfoot RW Jr, et al. Methotrexate for rheumatoid arthritis: suggested guidelines for monitoring liver toxicity. Arthritis Rheum 1994;37:316-28.
    • (1994) Arthritis Rheum , vol.37 , pp. 316-328
    • Kremer, J.M.1    Alarcon, G.S.2    Lightfoot R.W., Jr.3
  • 37
    • 15444350253 scopus 로고    scopus 로고
    • Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: A multicenter study with literature review
    • Kremer JM, Alarcon GS, Weinblatt ME, et al. Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: a multicenter study with literature review. Arthritis Rheum 1997;40:1829-37.
    • (1997) Arthritis Rheum , vol.40 , pp. 1829-1837
    • Kremer, J.M.1    Alarcon, G.S.2    Weinblatt, M.E.3
  • 38
    • 0027170585 scopus 로고
    • Pancytopenia associated with low dose methotrexate therapy: A regional survey
    • al-Awadhi A, Dale P, McKendry RJ. Pancytopenia associated with low dose methotrexate therapy: a regional survey. J Rheumatol 1993;20:1121-5.
    • (1993) J Rheumatol , vol.20 , pp. 1121-1125
    • Al-Awadhi, A.1    Dale, P.2    McKendry, R.J.3
  • 39
    • 0031965519 scopus 로고    scopus 로고
    • Adult and two children with fetal methotrexate syndrome
    • Bawle EV, Conard JV, Weiss L. Adult and two children with fetal methotrexate syndrome. Teratology 1998;57:51-5.
    • (1998) Teratology , vol.57 , pp. 51-55
    • Bawle, E.V.1    Conard, J.V.2    Weiss, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.