메뉴 건너뛰기




Volumn 11, Issue 9, 2004, Pages 1293-1299

Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics

Author keywords

[No Author keywords available]

Indexed keywords

CORONAVIRUS; SARS CORONAVIRUS;

EID: 4644343545     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.07.013     Document Type: Article
Times cited : (150)

References (27)
  • 1
    • 4644323762 scopus 로고    scopus 로고
    • World Health Organization (WHO). (www.who.int/csr/sars/en/).
  • 10
    • 0033615357 scopus 로고    scopus 로고
    • Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
    • Mayer T.U., Kapoor T.M., Haggarty S.J., King R.W., Schreiber S.L., Mitchison T.J. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science. 286:1999;971-974
    • (1999) Science , vol.286 , pp. 971-974
    • Mayer, T.U.1    Kapoor, T.M.2    Haggarty, S.J.3    King, R.W.4    Schreiber, S.L.5    Mitchison, T.J.6
  • 11
    • 0034700166 scopus 로고    scopus 로고
    • Small molecule developmental screens reveal the logic and timing of vertebrate development
    • Peterson R.T., Link B.A., Dowling J.E., Schreiber S.L. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc. Natl. Acad. Sci. USA. 97:2000;12965-12969
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12965-12969
    • Peterson, R.T.1    Link, B.A.2    Dowling, J.E.3    Schreiber, S.L.4
  • 12
    • 0037162499 scopus 로고    scopus 로고
    • A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity
    • Kao R.Y., Jenkins J.L., Olson K.A., Key M.E., Fett J.W., Shapiro R. A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity. Proc. Natl. Acad. Sci. USA. 99:2002;10066-10071
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10066-10071
    • Kao, R.Y.1    Jenkins, J.L.2    Olson, K.A.3    Key, M.E.4    Fett, J.W.5    Shapiro, R.6
  • 13
    • 0037061492 scopus 로고    scopus 로고
    • Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays
    • Kuruvilla F.G., Shamji A.F., Sternson S.M., Hergenrother P.J., Schreiber S.L. Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays. Nature. 416:2002;653-657
    • (2002) Nature , vol.416 , pp. 653-657
    • Kuruvilla, F.G.1    Shamji, A.F.2    Sternson, S.M.3    Hergenrother, P.J.4    Schreiber, S.L.5
  • 14
    • 0028505040 scopus 로고
    • Towards a pharmacological genetics
    • Mitchison T.J. Towards a pharmacological genetics. Chem. Biol. 1:1994;3-6
    • (1994) Chem. Biol. , vol.1 , pp. 3-6
    • Mitchison, T.J.1
  • 15
    • 0031710509 scopus 로고    scopus 로고
    • Chemical genetics resulting from a passion for synthetic organic chemistry
    • Schreiber S.L. Chemical genetics resulting from a passion for synthetic organic chemistry. Bioorg. Med. Chem. 6:1998;1127-1152
    • (1998) Bioorg. Med. Chem. , vol.6 , pp. 1127-1152
    • Schreiber, S.L.1
  • 16
    • 0034331004 scopus 로고    scopus 로고
    • Chemical genetics: Ligand-based discovery of gene function
    • Stockwell B.R. Chemical genetics. ligand-based discovery of gene function Nat. Rev. Genet. 1:2000;116-125
    • (2000) Nat. Rev. Genet. , vol.1 , pp. 116-125
    • Stockwell, B.R.1
  • 18
    • 0141869946 scopus 로고    scopus 로고
    • Early events of SARS coronavirus infection in vero cells
    • Ng M.L., Tan S.H., See E.E., Ooi E.E., Ling A.E. Early events of SARS coronavirus infection in vero cells. J. Med. Virol. 71:2003;323-331
    • (2003) J. Med. Virol. , vol.71 , pp. 323-331
    • Ng, M.L.1    Tan, S.H.2    See, E.E.3    Ooi, E.E.4    Ling, A.E.5
  • 19
    • 0348013197 scopus 로고    scopus 로고
    • Proliferative growth of SARS coronavirus in Vero E6 cells
    • Ng M.L., Tan S.H., See E.E., Ooi E.E., Ling A.E. Proliferative growth of SARS coronavirus in Vero E6 cells. J. Gen. Virol. 84:2003;3291-3303
    • (2003) J. Gen. Virol. , vol.84 , pp. 3291-3303
    • Ng, M.L.1    Tan, S.H.2    See, E.E.3    Ooi, E.E.4    Ling, A.E.5
  • 20
    • 0038120984 scopus 로고    scopus 로고
    • Coronavirus main proteinase (3CLpro) structure: Basis for design of anti-SARS drugs
    • Anand K., Ziebuhr J., Wadhwani P., Mesters J.R., Hilgenfeld R. Coronavirus main proteinase (3CLpro) structure. basis for design of anti-SARS drugs Science. 300:2003;1763-1767
    • (2003) Science , vol.300 , pp. 1763-1767
    • Anand, K.1    Ziebuhr, J.2    Wadhwani, P.3    Mesters, J.R.4    Hilgenfeld, R.5
  • 21
    • 0242458317 scopus 로고    scopus 로고
    • Assessment of putative protein targets derived from the SARS genome
    • Yan L., Velikanov M., Flook P., Zheng W., Szalma S., Kahn S. Assessment of putative protein targets derived from the SARS genome. FEBS Lett. 554:2003;257-263
    • (2003) FEBS Lett. , vol.554 , pp. 257-263
    • Yan, L.1    Velikanov, M.2    Flook, P.3    Zheng, W.4    Szalma, S.5    Kahn, S.6
  • 22
    • 0345255626 scopus 로고    scopus 로고
    • The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
    • Yang H., Yang M., Ding Y., Liu Y., Lou Z., Zhou Z., Sun L., Mo L., Ye S., Pang H., et al. The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor. Proc. Natl. Acad. Sci. USA. 100:2003;13190-13195
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 13190-13195
    • Yang, H.1    Yang, M.2    Ding, Y.3    Liu, Y.4    Lou, Z.5    Zhou, Z.6    Sun, L.7    Mo, L.8    Ye, S.9    Pang, H.10
  • 24
    • 0141960168 scopus 로고    scopus 로고
    • The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5′ to 3′ viral helicases
    • Tanner J.A., Watt R.M., Chai Y.B., Lu L.Y., Lin M.C., Peiris J.S., Poon L.L., Kung H.F., Huang J.D. The severe acute respiratory syndrome (SARS) coronavirus NTPase/helicase belongs to a distinct class of 5′ to 3′ viral helicases. J. Biol. Chem. 278:2003;39578-39582
    • (2003) J. Biol. Chem. , vol.278 , pp. 39578-39582
    • Tanner, J.A.1    Watt, R.M.2    Chai, Y.B.3    Lu, L.Y.4    Lin, M.C.5    Peiris, J.S.6    Poon, L.L.7    Kung, H.F.8    Huang, J.D.9
  • 27
    • 0035996748 scopus 로고    scopus 로고
    • Recombinant expression and purification of an enzymatically active cysteine proteinase of the protozoan parasite Entamoeba histolytica
    • Hellberg A., Nowak N., Leippe M., Tannich E., Bruchhaus I. Recombinant expression and purification of an enzymatically active cysteine proteinase of the protozoan parasite Entamoeba histolytica. Protein Expr. Purif. 24:2002;131-137
    • (2002) Protein Expr. Purif. , vol.24 , pp. 131-137
    • Hellberg, A.1    Nowak, N.2    Leippe, M.3    Tannich, E.4    Bruchhaus, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.