The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 23, 2003, Pages 13190-13195

  Yang, Haitao ^a   Yang, Maojun ^a   Ding, Yi ^a   Liu, Yiwei ^a   Lou, Zhiyong ^a   Zhou, Zhe ^a   Sun, Lei ^a   Mo, Lijuan ^a   Ye, Sheng ^a   Pang, Hai ^a   Gao, George F ^a   Anand, Kanchan ^b   Bartlam, Mark ^a   Hilgenfeld, Rolf ^b   Rao, Zihe ^a  

^a TSINGHUA UNIVERSITY   (China)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; VIRUS PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORONAVIRUS; CRYSTAL STRUCTURE; ENZYME STRUCTURE; EPIDEMIC; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFECTION; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRUS REPLICATION;

AMINO ACID CHLOROMETHYL KETONES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; GLUTATHIONE TRANSFERASE; HISTIDINE; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SARS VIRUS; SUBSTRATE SPECIFICITY; TIME FACTORS; VIRAL PROTEINS;

CORONAVIRUS; RNA VIRUSES; SARS CORONAVIRUS;

EID: 0345255626     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1835675100     Document Type: Article

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