2-(4-aminophenyl) benzothiazole: A potent and selective pharmacophore with novel mechanistic action towards various tumour cell lines

Mini-Reviews in Medicinal Chemistry

Volumn 6, Issue 6, 2006, Pages 633-637

  Dubey, Raghvendra ^a   Shrivastava, Prabhat K ^a   Basniwal, Pawan K ^a   Bhattacharya, Snehendu ^a   Moorthy, Narayana S Hari Narayana ^a  

^a UNIVERSITY INSTITUTE OF TECHNOLOGY   (India)

Author keywords

2 (4 aminophenyl) benzothiazole; Antitumour agents; Aryl hydrocarbon receptor (AhR); Cytochrome P 450 isoform CYP1A1; DNA adduct

Indexed keywords

2 (4 AMINO 3 METHYLPHENYL)BENZOTHIAZOLE; 2 (4 AMINOPHENYL)BENZOTHIAZOLE; 2 (4 AMINOPHENYL)BENZOTHIAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT; AROMATIC HYDROCARBON; AROMATIC HYDROCARBON RECEPTOR; BENZOTHIAZOLE DERIVATIVE; CJM 126; CYTOCHROME P450 1A1; DF 129; DF 229; DRUG METABOLITE; HALOGEN; PRODRUG; UNCLASSIFIED DRUG;

ACETYLATION; APOPTOSIS; ARTICLE; BREAST TUMOR; CANCER INHIBITION; CELL DEATH; COLON TUMOR; DNA ADDUCT; DRUG BIOAVAILABILITY; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; ENZYME INDUCTION; HUMAN; IN VITRO STUDY; KIDNEY TUMOR; OVARY TUMOR; OXIDATION; PHARMACOPHORE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; ENZYME ACTIVATION; HUMANS; RECEPTORS, ARYL HYDROCARBON; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 33745113189     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955706777435706     Document Type: Article

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