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Volumn 77, Issue 5, 1998, Pages 745-752

2-(4-Aminophenyl)benzothiazoles: Novel agents with selective profiles of in vitro anti-tumour activity

Author keywords

2 (4 aminophenyl)benzothiazole; Biphasic dose response; Selective anti tumour activity

Indexed keywords

BENZOTHIAZOLE DERIVATIVE; CJM 126; DOXORUBICIN; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 0031933503     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.122     Document Type: Article
Times cited : (243)

References (18)
  • 1
    • 0029792884 scopus 로고    scopus 로고
    • Novel 5-aminoflavone derivatives as specific antitumour agents in breast cancer
    • Akama T, Yasushi S, Sugaya T, Ishida H, Gomi K and Kasai M (1996) Novel 5-aminoflavone derivatives as specific antitumour agents in breast cancer. J Med Chem 39: 3461-3469
    • (1996) J Med Chem , vol.39 , pp. 3461-3469
    • Akama, T.1    Yasushi, S.2    Sugaya, T.3    Ishida, H.4    Gomi, K.5    Kasai, M.6
  • 2
    • 0028906786 scopus 로고
    • Some practical considerations and applications of the National Cancer Institute in vitro anticancer drug discovery screen
    • Boyd MR and Paull KD (1995) Some practical considerations and applications of the National Cancer Institute in vitro anticancer drug discovery screen. Drug Devel Res 34: 91-109
    • (1995) Drug Devel Res , vol.34 , pp. 91-109
    • Boyd, M.R.1    Paull, K.D.2
  • 4
    • 0026593809 scopus 로고
    • Cytostatic and cytotoxic effects of fostriecin on human promyelocytic HL-60 and lymphocytic MOLT-4 leukaemic cells
    • Hotz MA, Del Bino G, Lassota P, Traganos H and Darzynkiewics Z (1992) Cytostatic and cytotoxic effects of fostriecin on human promyelocytic HL-60 and lymphocytic MOLT-4 leukaemic cells. Cancer Res 52: 1530-1535
    • (1992) Cancer Res , vol.52 , pp. 1530-1535
    • Hotz, M.A.1    Del Bino, G.2    Lassota, P.3    Traganos, H.4    Darzynkiewics, Z.5
  • 5
    • 0014697549 scopus 로고
    • Enzymes in rat urine. 1. A metabolism cage for complete separation of urine and faeces
    • Leathwood PD and Plummer DT (1969) Enzymes in rat urine. 1. A metabolism cage for complete separation of urine and faeces. Enzymologia 37: 240-250
    • (1969) Enzymologia , vol.37 , pp. 240-250
    • Leathwood, P.D.1    Plummer, D.T.2
  • 6
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani H and Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139: 271-279
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, H.4    Riccardi, C.5
  • 7
    • 0028150702 scopus 로고
    • Growth-inhibitory effects of the natural phytooestrogen Genistein in MCF-7 human breast cancer cells
    • Pagliacci MC, Smacchia M, Migliorati G, Grignani F, Riccardi C and Nicoletti I (1994) Growth-inhibitory effects of the natural phytooestrogen Genistein in MCF-7 human breast cancer cells. Eur J Cancer 30A: 1675-1682
    • (1994) Eur J Cancer , vol.30 A , pp. 1675-1682
    • Pagliacci, M.C.1    Smacchia, M.2    Migliorati, G.3    Grignani, F.4    Riccardi, C.5    Nicoletti, I.6
  • 8
    • 0029589690 scopus 로고
    • Differences in resistance to 5-fluorouracil as a function of cell cycle delay and not apoptosis
    • Pickard M, Dive C and Kinsella AR (1995) Differences in resistance to 5-fluorouracil as a function of cell cycle delay and not apoptosis. Br J Cancer 72: 1389-1396
    • (1995) Br J Cancer , vol.72 , pp. 1389-1396
    • Pickard, M.1    Dive, C.2    Kinsella, A.R.3
  • 9
    • 0004211829 scopus 로고
    • Oxford University Press: New York
    • Ruddon RW (1987) Cancer Biology, 2nd edn. pp. 200-202. Oxford University Press: New York
    • (1987) Cancer Biology, 2nd Edn. , pp. 200-202
    • Ruddon, R.W.1
  • 10
    • 0029934427 scopus 로고    scopus 로고
    • N-Acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland
    • Sadrieh N, Davis CD and Snyderwyne EG (1996) N-Acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland. Cancer Res 56: 2683-2687
    • (1996) Cancer Res , vol.56 , pp. 2683-2687
    • Sadrieh, N.1    Davis, C.D.2    Snyderwyne, E.G.3
  • 11
    • 0030271680 scopus 로고    scopus 로고
    • Efficacy of dinaline und its methyl and acetyl derivatives against colorectal cancer in vivo and in vitro
    • Seelig MH and Berger MR (1996) Efficacy of dinaline und its methyl and acetyl derivatives against colorectal cancer in vivo and in vitro. Eur J Cancer 32A: 1968-1976
    • (1996) Eur J Cancer , vol.32 A , pp. 1968-1976
    • Seelig, M.H.1    Berger, M.R.2
  • 12
    • 0029780539 scopus 로고    scopus 로고
    • Antitumour benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo
    • Shi D-F, Bradshaw TD, Wrigley S, McCall CJ, Lelieveld P, Fichtner I and Stevens MFG (1996) Antitumour benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo. J Med Chem 39: 3375-3384
    • (1996) J Med Chem , vol.39 , pp. 3375-3384
    • Shi, D.-F.1    Bradshaw, T.D.2    Wrigley, S.3    McCall, C.J.4    Lelieveld, P.5    Fichtner, I.6    Stevens, M.F.G.7
  • 13
    • 0028241286 scopus 로고
    • Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin
    • Stevens MFG, McCall CJ, Lelieveld P, Alexander P, Richter A and Davies DH (1994) Structural studies on bioactive compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with genistein and quercetin. J Med Chem 37: 1689-1695
    • (1994) J Med Chem , vol.37 , pp. 1689-1695
    • Stevens, M.F.G.1    McCall, C.J.2    Lelieveld, P.3    Alexander, P.4    Richter, A.5    Davies, D.H.6
  • 14
    • 15144351812 scopus 로고
    • International Publication Number WO 95/06469; Stevens MFG, Shi D-F, Bradshaw TD and Wrigley S, Benzazole compound. Br. Patent, 9503946.7
    • Stevens MFG, McCall CJ and Lelieveld P (1995) Benzazole compounds fur use in therapy. International Publication Number WO 95/06469; Stevens MFG, Shi D-F, Bradshaw TD and Wrigley S, Benzazole compound. Br. Patent, 9503946.7
    • (1995) Benzazole Compounds fur Use in Therapy
    • Stevens, M.F.G.1    McCall, C.J.2    Lelieveld, P.3
  • 16
    • 0002582585 scopus 로고    scopus 로고
    • Antitumour benzothiazoles. Part 4. An NMR study of the sites of protonation of 2-(4-aminophenyl)benzothiazoles
    • Wheelhouse RT, Shi D-F, Wilman DEV and Stevens MFG (1996) Antitumour benzothiazoles. Part 4. An NMR study of the sites of protonation of 2-(4-aminophenyl)benzothiazoles. J Chem Soc Perkin Trans 2: 1271-1274
    • (1996) J Chem Soc Perkin Trans , vol.2 , pp. 1271-1274
    • Wheelhouse, R.T.1    Shi, D.-F.2    Wilman, D.E.V.3    Stevens, M.F.G.4
  • 17
    • 0028800512 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Molecular mechanism of carcinogenesis and its implication in human in vitro model
    • Yang J-H and Rhim JS (1995). 2,3,7,8-Tetrachlorodibenzo-p-dioxin: molecular mechanism of carcinogenesis and its implication in human in vitro model. Crit Rev Oncol/Hematol 18: 111-127
    • (1995) Crit Rev Oncol/Hematol , vol.18 , pp. 111-127
    • Yang, J.-H.1    Rhim, J.S.2
  • 18
    • 0025909059 scopus 로고
    • Structural studies on benzothiazoles. Crystal and molecular structure of 5,6-dimethoxy-2-(4-methoxyphenyl)benzothiazole and molecular orbital calculations on related compounds
    • Yates PC, McCall CJ and Stevens MFG (1991) Structural studies on benzothiazoles. Crystal and molecular structure of 5,6-dimethoxy-2-(4-methoxyphenyl)benzothiazole and molecular orbital calculations on related compounds. Tetrahedron 47: 6493-6502
    • (1991) Tetrahedron , vol.47 , pp. 6493-6502
    • Yates, P.C.1    McCall, C.J.2    Stevens, M.F.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.