HIV-1 RNase H: Recent progress in an exciting, yet little explored, drug target

Mini-Reviews in Medicinal Chemistry

Volumn 6, Issue 6, 2006, Pages 727-737

  Tramontano, Enzo ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Diketo acids; Drug development; HIV 1; Inhibition; N hydroxyimides; Reverse transcriptase; Ribonuclease H

Indexed keywords

(4,N,N DIMETHYLAMINOBENZOYL) 2 HYDROXYL 1 NAPHTHYLHYDRAZONE; 1,4 NAPHTHOQUINONE DERIVATIVE; 2',3' DIDEOXYADENOSINE PHOSPHATE; 2',3' DIDEOXYGUANOSINE 5' PHOSPHATE; 3,5,8 TRIHYDROXY 4 QUINOLONE; 4 AMINO 3 HYDROXY 1 NAPHTHALENESULFONIC ACID; AVARONE; CHELATING AGENT; DEXTRAN SULFATE; DRYOPTERIS EXTRACT; HEPARIN; HERBACEOUS AGENT; HYDRAZONE DERIVATIVE; ILLIMAQUINONE; KMMP 05; METAL ION; N (4 TERT BUTYLBENZOYL) 2 HYDROXY 1 NAPHTHALDEHYDE HYDRAZONE; N (4 TERT BUTYLBENZOYL) 2 HYDROXY 1 SALICYLHYDRAZONE; NAPHTHALENESULFONIC ACID DERIVATIVE; NEVIRAPINE; NUCLEOSIDE DERIVATIVE; PENTOSAN POLYSULFATE; POLYANION; RIBONUCLEASE H; SESQUITERPENOID; STAVUDINE; TERTAGALLOYLGLUCOPYRANOSE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZIDOVUDINE; ZIDOVUDINE 5' PHOSPHATE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIVIRAL ACTIVITY; DRUG RESEARCH; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME INHIBITION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; REVIEW;

ANTI-HIV AGENTS; BINDING SITES; HIV-1; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEASE H, CALF THYMUS;

EID: 33745107517     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955706777435733     Document Type: Review

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