Alanine-scanning mutations in the 'primer grip' of p66 HIV-1 reverse transcriptase result in selective loss of RNA priming activity

Journal of Biological Chemistry

Volumn 272, Issue 20, 1997, Pages 13262-13269

  Powell, Michael D ^a   Ghosh, Madhumita ^b   Jacques, Pamela S ^b   Howard, Kathryn J ^b   Le Grice, Stuart F J ^b   Levin, Judith G ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; PURINE; RNA DIRECTED DNA POLYMERASE;

AMINO ACID SUBSTITUTION; ARTICLE; DISEASE SEVERITY; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL;

ALANINE; AMINO ACID SEQUENCE; GENE EXPRESSION REGULATION, VIRAL; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; RNA; RNA, VIRAL;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030977397     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.20.13262     Document Type: Article

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