Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors

Molecular Pharmacology

Volumn 62, Issue 2, 2002, Pages 398-405

  Sluis Cremer, Nicolas ^a   Arion, Dominique ^a   Parniak, Michael A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(4 TERT BUTYLBENZOYL) 2 HYDROXY 1 SALICYLYLHYDRAZONE; (4N,N DIMETHYLAMINOBENZOYL) 2 HYDROXY 1 NAPHTHYLHYDRAZONE; DIMER; DNA POLYMERASE; N (4 TERT BUTYLBENZOYL) 2 HYDROXY 1 NAPHTHALDEHYDE HYDRAZONE; N ACYLHYDRAZONE DERIVATIVE; NEVIRAPINE; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; UREA;

ARTICLE; DISSOCIATION; DNA SYNTHESIS; DRUG STRUCTURE; DRUG SYNTHESIS; ENERGY; ENZYME ACTIVITY; ENZYME DENATURATION; ENZYME INHIBITION; ENZYME STABILITY; HUMAN IMMUNODEFICIENCY VIRUS 1; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

DIMERIZATION; DNA-DIRECTED DNA POLYMERASE; ENZYME STABILITY; HIV-1 REVERSE TRANSCRIPTASE; HYDRAZONES; NAPHTHALENES; REVERSE TRANSCRIPTASE INHIBITORS; UREA;

EID: 0036076157     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.2.398     Document Type: Article

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