Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow

Journal of Cell Science

Volumn 119, Issue 9, 2006, Pages 1760-1768

  Lee, Jerry S H ^a   Panorchan, Porntula ^a   Hale, Christopher M ^a   Khatau, Shyam B ^a   Kole, Thomas P ^a   Tseng, Yiider ^a,b   Wirtz, Denis ^a,c  

^a Johns Hopkins University   (United States)

^b University of Florida   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Actin; Cell mechanisms; Fluid shear stress; Microtubule; Rho GTPases

Indexed keywords

ACTIN; MYOSIN ADENOSINE TRIPHOSPHATASE; NANOPARTICLE; RHO KINASE;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CELL ADHESION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; ENZYME INHIBITION; FIBROBLAST; FLOW KINETICS; FLUID FLOW; FLUORESCENCE ANALYSIS; FOCAL ADHESION; INTRACELLULAR SPACE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SHEAR FLOW; SHEAR STRESS; STRESS FIBER; VISCOELASTICITY;

3T3 CELLS; ACTINS; ANIMALS; CELL ADHESION; CYTOSKELETON; CYTOSOL; FIBROBLASTS; FLUORESCENT DYES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYSOPHOSPHOLIPIDS; MICE; MICROINJECTIONS; MYOSINS; NANOPARTICLES; NANOTECHNOLOGY; PROTEIN-SERINE-THREONINE KINASES; RHEOLOGY; RHO-ASSOCIATED KINASES; SHEAR STRENGTH; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

ANIMALIA;

EID: 33744509705     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02899     Document Type: Article

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