Localized Cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress

Journal of Biological Chemistry

Volumn 278, Issue 33, 2003, Pages 31020-31023

  Tzima, Eleni ^b   Kiosses, William B ^b   Del Pozo, Miguel A ^b   Schwartz, Martin Alexander ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; CHEMICAL BONDS; ENZYMES; FLOW OF FLUIDS; PHYSIOLOGY; SHEAR STRESS;

ENDOTHELIAL CELLS;

CYTOLOGY;

GUANOSINE TRIPHOSPHATASE; INTEGRIN; PROTEIN CDC42; PROTEIN KINASE C ZETA;

ANIMAL CELL; ARTICLE; CELL MOTION; CELL NUCLEUS; CELL POLARITY; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; DYNAMICS; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; ENERGY TRANSFER; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FLUID FLOW; FLUORESCENCE; GOLGI COMPLEX; MICROTUBULE ORGANIZING CENTER; MORPHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; POLARIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; SHEAR STRESS;

ANIMALS; AORTA; CATTLE; CDC42 GTP-BINDING PROTEIN; CELL POLARITY; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GREEN FLUORESCENT PROTEINS; INDICATORS AND REAGENTS; INTEGRINS; LUMINESCENT PROTEINS; MICROTUBULE-ORGANIZING CENTER; PROTEIN KINASE C; RECOMBINANT FUSION PROTEINS; RHO GTP-BINDING PROTEINS; STRESS, MECHANICAL;

ANIMALIA;

EID: 0042232206     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301179200     Document Type: Article

References (37)

1. Nerem, R. M., and Girard, P. R. (1990) Toxicol. Pathol. 18, 572-582
2. Levesque, M. J., and Nerem, R. M. (1985) J. Biomech. Eng. 107, 341-347
3. Ives, C. L., Eskin, S. G., and McIntire, L. V. (1986) In Vitro Cell Dev. Biol. 22, 500-507
4. Rogers, K. A., McKee, N. H., and Kalnins, V. I. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 3272-3276
5. Kiosses, W. B., McKee, N. H., and Kalnins, V. I. (1997) Arterioscler. Thromb. Vasc. Biol. 17, 2891-2896
6. Kiosses, W. B., McKee, N. H., and Kalnins, V. I. (1997) Artery 22, 251-265
7. Gotlieb, A. I., and Spector, W. (1981) Am. J. Pathol. 103, 271-282
8. Malech, H. L., Root, R. K., and Gallin, J. I. (1977) J. Cell Biol. 75, 666-693
9. Koonce, M. P., Cloney, R. A., and Berns, M. W. (1984) J. Cell Biol. 98, 1999-2010
10. Palazzo, A. F., Joseph, H. L., Chen, Y. J., Dujardin, D. L., Alberts, A. S., Pfister, K. K., Vallee, R. B., and Gundersen, G. G. (2001) Curr. Biol. 11, 1536-1541
11. Etienne-Manneville, S., and Hall, A. (2001) Cell 106, 489-498
12. Gao, L., Joberty, G., and Macara, I. G. (2002) Curr. Biol. 12, 221-225
13. Fukata, M., Watanabe, T., Noritake, J., Nakagawa, M., Yamaga, M., Kuroda, S., Matsuura, Y., Iwamatsu, A., Perez, F., and Kaibuchi, K. (2002) Cell 109, 873-885
14. Tzima, E., del Pozo, M. A., Shattil, S. J., Chien, S., and Schwartz, M. A. (2001) EMBO J. 20, 4639-4647
15. Tzima, E., Del Pozo, M. A., Kiosses, W. B., Mohamed, S. A., Li, S., Chien, S., and Schwartz, M. A. (2002) EMBO J. 21, 6791-6800
16. del Pozo, M. A., Price, L. S., Alderson, N. B., Ren, X. D., and Schwartz, M. A. (2000) EMBO J. 19, 2008-2014
17. Kiosses, W. B., Daniels, R. H., Otey, C., Bokoch, G. M., and Schwartz, M. A. (1999) J. Cell Biol. 147, 831-844
18. Clarke, M. S., and McNeil, P. L. (1992) J. Cell Sci. 102, 533-541
19. Kraynov, V. S., Chamberlain, C., Bokoch, G. M., Schwartz, M. A., Slabaugh, S., and Hahn, K. M. (2000) Science 290, 333-337
20. Bagrodia, S., Derijard, B., Davis, R. J., and Cerione, R. A. (1995) J. Biol. Chem. 270, 27995-27998
21. Benard, V., Bohl, B. P., and Bokoch, G. M. (1999) J. Biol. Chem. 274, 13198-13204
22. Li, S., Chen, B. P., Azuma, N., Hu, Y. L., Wu, S. Z., Sumpio, B. E., Shyy, J. Y., and Chien, S. (1999) J. Clin. Invest. 103, 1141-1150
23. Del Pozo, M. A., Kiosses, W. B., Alderson, N. B., Meller, N., Hahn, K. M., and Schwartz, M. A. (2002) Nat. Cell Biol. 4, 232-239
24. Jalali, S., del Pozo, M. M., Chen, Y. D., Miao, H., Li, Y. S., Schwartz, M. A., Shyy, J. Y., and Chien, S. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 1042-1046
25. Price, L. S., Leng, J., Schwartz, M. A., and Bokoch, G. M. (1998) Mol. Biol. Cell 9, 1863-1871
26. Malek, A. M., and Izumo, S. (1996) J. Cell Sci. 109, 713-726
27. Chamberlain, C. E., Kraynov, V. S., and Hahn, K. M. (2000) Methods Enzymol. 325, 389-400
28. Meller, N., Irani-Tehrani, M., Kiosses, W. B., Del Pozo, M. A., and Schwartz, M. A. (2002) Nat. Cell Biol. 4, 639-647
29. Tran Van Nhieu, G., Caron, E., Hall, A., and Sansonetti, P. J. (1999) EMBO J. 18, 3249-3262
30. Etienne-Manneville, S., and Hall, A. (2003) Curr. Opin. Cell Biol. 15, 67-72
31. Joberty, G., Petersen, C., Gao, L., and Macara, I. G. (2000) Nat. Cell Biol. 2, 531-539
32. Cox, E. A., Sastry, S. K., and Huttenlocher, A. (2001) Mol. Biol. Cell 12, 265-277
33. Davies, P. F., Robotewskyj, A., and Griem, M. L. (1994) J. Clin. Invest. 93, 2031-2038
34. Hall, A. (1998) Science 279, 509-514
35. Itoh, R. E., Kurokawa, Y., Ohba, Y., Yoshizaki, H., Mochizuki, N., and Matsuda, M. (2002) Mol. Cell. Biol. 22, 6582-6591
36. Kemphues, K. J., Priess, J. R., Morton, D. G., and Cheng, N. S. (1988) Cell 52, 311-320
37. Oakley, C., and Brunette, D. M. (1993) J. Cell Sci. 106, 343-354