메뉴 건너뛰기




Volumn 273, Issue 8, 2006, Pages 1609-1619

DNA mismatch repair system: Classical and fresh roles

Author keywords

Antibody diversification; DNA damage response; DNA mismatch repair; MutL; MutS

Indexed keywords

CISPLATIN; TEMOZOLOMIDE;

EID: 33646872909     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05190.x     Document Type: Short Survey
Times cited : (78)

References (89)
  • 1
    • 0013579690 scopus 로고
    • Repair tracts in mismatched DNA heteroduplexes
    • Wagner R Meselson M 1976 Repair tracts in mismatched DNA heteroduplexes. Proc Natl Acad Sci USA 73, 4135 4139.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 4135-4139
    • Wagner, R.1    Meselson, M.2
  • 2
    • 0015453608 scopus 로고
    • Mutator gene studies in Escherichia coli: The mutS gene
    • Cox EC Degnen GE Scheppe ML 1972 Mutator gene studies in Escherichia coli: the mutS gene. Genetics 72, 551 567.
    • (1972) Genetics , vol.72 , pp. 551-567
    • Cox, E.C.1    Degnen, G.E.2    Scheppe, M.L.3
  • 3
    • 0029943449 scopus 로고    scopus 로고
    • Mismatch repair in replication fidelity, genetic recombination, and cancer biology
    • Modrich P Lahue R 1996 Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu Rev Biochem 65, 101 133.
    • (1996) Annu Rev Biochem , vol.65 , pp. 101-133
    • Modrich, P.1    Lahue, R.2
  • 5
    • 0034641938 scopus 로고    scopus 로고
    • Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
    • Obmolova G Ban C Hsieh P Yang W 2000 Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature 407, 703 710.
    • (2000) Nature , vol.407 , pp. 703-710
    • Obmolova, G.1    Ban, C.2    Hsieh, P.3    Yang, W.4
  • 7
    • 0035102126 scopus 로고    scopus 로고
    • Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair
    • Junop MS Obmolova G Rausch K Hsieh P Yang W 2001 Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair. Mol Cell 7, 1 12.
    • (2001) Mol Cell , vol.7 , pp. 1-12
    • Junop, M.S.1    Obmolova, G.2    Rausch, K.3    Hsieh, P.4    Yang, W.5
  • 8
    • 0037415693 scopus 로고    scopus 로고
    • The alternating ATPase domains of MutS control DNA mismatch repair
    • Lamers MH Winterwerp HH Sixma TK 2003 The alternating ATPase domains of MutS control DNA mismatch repair. EMBO J 22, 746 756.
    • (2003) EMBO J , vol.22 , pp. 746-756
    • Lamers, M.H.1    Winterwerp, H.H.2    Sixma, T.K.3
  • 12
    • 0027522357 scopus 로고
    • Molecular matchmakers
    • Sancar A Hearst JE 1993 Molecular matchmakers. Science 259, 1415 1420.
    • (1993) Science , vol.259 , pp. 1415-1420
    • Sancar, A.1    Hearst, J.E.2
  • 13
    • 0033151816 scopus 로고    scopus 로고
    • ATP hydrolysis-dependent formation of a dynamic ternary nucleoprotein complex with MutS and MutL
    • Galio L Bouquet C Brooks P 1999 ATP hydrolysis-dependent formation of a dynamic ternary nucleoprotein complex with MutS and MutL. Nucleic Acids Res 27, 2325 2331.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2325-2331
    • Galio, L.1    Bouquet, C.2    Brooks, P.3
  • 14
    • 0033555922 scopus 로고    scopus 로고
    • The Escherichia coli MutL protein physically interacts with MutH and stimulates the MutH-associated endonuclease activity
    • Hall MC Matson SW 1999 The Escherichia coli MutL protein physically interacts with MutH and stimulates the MutH-associated endonuclease activity. J Biol Chem 274, 1306 1312.
    • (1999) J Biol Chem , vol.274 , pp. 1306-1312
    • Hall, M.C.1    Matson, S.W.2
  • 15
    • 0032502779 scopus 로고    scopus 로고
    • Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex
    • Dao V Modrich P 1998 Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex. J Biol Chem 273, 9202 9207.
    • (1998) J Biol Chem , vol.273 , pp. 9202-9207
    • Dao, V.1    Modrich, P.2
  • 16
    • 0032473429 scopus 로고    scopus 로고
    • Evidence for a physical interaction between the Escherichia coli methyl-directed mismatch repair proteins MutL and UvrD
    • Hall MC Jordan JR Matson SW 1998 Evidence for a physical interaction between the Escherichia coli methyl-directed mismatch repair proteins MutL and UvrD. EMBO J 17, 1535 1541.
    • (1998) EMBO J , vol.17 , pp. 1535-1541
    • Hall, M.C.1    Jordan, J.R.2    Matson, S.W.3
  • 17
    • 0032514843 scopus 로고    scopus 로고
    • Crystal structure and ATPase activity of MutL: Implications for DNA repair and mutagenesis
    • Ban C Yang W 1998 Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis. Cell 95, 541 552.
    • (1998) Cell , vol.95 , pp. 541-552
    • Ban, C.1    Yang, W.2
  • 18
    • 0033515522 scopus 로고    scopus 로고
    • Transformation of MutL by ATP binding and hydrolysis: A switch in DNA mismatch repair
    • Ban C Junop M Yang W 1999 Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell 97, 85 97.
    • (1999) Cell , vol.97 , pp. 85-97
    • Ban, C.1    Junop, M.2    Yang, W.3
  • 19
    • 9144274423 scopus 로고    scopus 로고
    • Structure of the MutL C-terminal domain: A model of intact MutL and its roles in mismatch repair
    • Guarne A Ramon-Maiques S Wolff EM Ghirlando R Hu X Miller JH Yang W 2004 Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair. EMBO J 23, 4134 4145.
    • (2004) EMBO J , vol.23 , pp. 4134-4145
    • Guarne, A.1    Ramon-Maiques, S.2    Wolff, E.M.3    Ghirlando, R.4    Hu, X.5    Miller, J.H.6    Yang, W.7
  • 20
    • 0026637946 scopus 로고
    • Initiation of methyl-directed mismatch repair
    • Au KG Welsh K Modrich P 1992 Initiation of methyl-directed mismatch repair. J Biol Chem 267, 12142 12148.
    • (1992) J Biol Chem , vol.267 , pp. 12142-12148
    • Au, K.G.1    Welsh, K.2    Modrich, P.3
  • 21
    • 0032473571 scopus 로고    scopus 로고
    • Structural basis for MutH activation in E. coli mismatch repair and relationship of MutH to restriction endonucleases
    • Ban C Yang W 1998 Structural basis for MutH activation in E. coli mismatch repair and relationship of MutH to restriction endonucleases. EMBO J 17, 1526 1534.
    • (1998) EMBO J , vol.17 , pp. 1526-1534
    • Ban, C.1    Yang, W.2
  • 23
    • 0029784320 scopus 로고    scopus 로고
    • Biochemistry and genetics of eukaryotic mismatch repair
    • Kolodner RD 1996 Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 10, 1433 1442.
    • (1996) Genes Dev , vol.10 , pp. 1433-1442
    • Kolodner, R.D.1
  • 24
    • 0026445628 scopus 로고
    • Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: Evidence for separate mitochondrial and nuclear functions
    • Reenan RAG Kolodner RD 1992 Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics 132, 975 985.
    • (1992) Genetics , vol.132 , pp. 975-985
    • Reenan, R.A.G.1    Kolodner, R.D.2
  • 25
    • 0028560427 scopus 로고
    • Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction
    • Ross-Macdonald P Roeder GS 1994 Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction. Cell 79, 1069 1080.
    • (1994) Cell , vol.79 , pp. 1069-1080
    • Ross-Macdonald, P.1    Roeder, G.S.2
  • 26
    • 0029868110 scopus 로고    scopus 로고
    • Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
    • Marsischky GT Filosi N Kane MF Kolodner R 1996 Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev 10, 407 420.
    • (1996) Genes Dev , vol.10 , pp. 407-420
    • Marsischky, G.T.1    Filosi, N.2    Kane, M.F.3    Kolodner, R.4
  • 27
    • 0032584384 scopus 로고    scopus 로고
    • Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα
    • Genschel J Littman SJ Drummond JT Modrich P 1998 Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα. J Biol Chem 273, 19895 19901.
    • (1998) J Biol Chem , vol.273 , pp. 19895-19901
    • Genschel, J.1    Littman, S.J.2    Drummond, J.T.3    Modrich, P.4
  • 29
    • 0024430850 scopus 로고
    • Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: Homology of PMS1 to procaryotic MutL and HexB
    • Kramer W Kramer B Williamson MS Fogel S 1989 Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB. J Bacteriol 171, 5339 5346.
    • (1989) J Bacteriol , vol.171 , pp. 5339-5346
    • Kramer, W.1    Kramer, B.2    Williamson, M.S.3    Fogel, S.4
  • 30
    • 0028157956 scopus 로고
    • Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene
    • Prolla T Christie DM Liskay RM 1994 Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol Cell Biol 14, 407 415.
    • (1994) Mol Cell Biol , vol.14 , pp. 407-415
    • Prolla, T.1    Christie, D.M.2    Liskay, R.M.3
  • 31
    • 0033598817 scopus 로고    scopus 로고
    • Functional specificity of MutL homologs in yeast: Evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction
    • Wang TF Kleckner N Hunter N 1999 Functional specificity of MutL homologs in yeast: Evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci USA 96, 13914 13919.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13914-13919
    • Wang, T.F.1    Kleckner, N.2    Hunter, N.3
  • 32
    • 0034628618 scopus 로고    scopus 로고
    • Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast
    • Harfe BD Minesinger BK Jinks-Robertson S 2000 Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10, 145 148.
    • (2000) Curr Biol , vol.10 , pp. 145-148
    • Harfe, B.D.1    Minesinger, B.K.2    Jinks-Robertson, S.3
  • 33
    • 0035477839 scopus 로고    scopus 로고
    • Structure and function of the N-terminal 40 kDa fragment of human PMS2: A monomeric GHL ATPase
    • Guarne A Junop MS Yang W 2001 Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase. EMBO J 20, 5521 5531.
    • (2001) EMBO J , vol.20 , pp. 5521-5531
    • Guarne, A.1    Junop, M.S.2    Yang, W.3
  • 34
    • 0034500024 scopus 로고    scopus 로고
    • DNA mismatch repair and genetic instability
    • Hafe BD Robertson SJ 2000 DNA mismatch repair and genetic instability. Annu Rev Genet 34, 359 399.
    • (2000) Annu Rev Genet , vol.34 , pp. 359-399
    • Hafe, B.D.1    Robertson, S.J.2
  • 35
    • 0025340001 scopus 로고
    • Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
    • Holmes J Clark S Modrich P 1990 Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc Natl Acad Sci USA 87, 5837 5841.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5837-5841
    • Holmes, J.1    Clark, S.2    Modrich, P.3
  • 36
    • 0037163128 scopus 로고    scopus 로고
    • DNA template requirements for human mismatch repair in vitro
    • q3
    • Iams K Larson ED Drummond JT 2002 DNA template requirements for human mismatch repair in vitro. J Biol Chem 277, 30805 30814. q3
    • (2002) J Biol Chem , vol.277 , pp. 30805-30814
    • Iams, K.1    Larson, E.D.2    Drummond, J.T.3
  • 37
    • 0029001791 scopus 로고
    • A multinational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair
    • q4
    • q4 Ayyagari R Impellizzeri KJ Yoder BL Gary SL Bergers PM 1995 A multinational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair. Mol Cell Biol 15, 4420 4429.
    • (1995) Mol Cell Biol , vol.15 , pp. 4420-4429
    • Ayyagari, R.1    Impellizzeri, K.J.2    Yoder, B.L.3    Gary, S.L.4    Bergers, P.M.5
  • 39
    • 0033764146 scopus 로고    scopus 로고
    • Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex
    • Flores-Rozas H Clark D Kolodner RD 2000 Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex. Nat Genet 26, 375 378.
    • (2000) Nat Genet , vol.26 , pp. 375-378
    • Flores-Rozas, H.1    Clark, D.2    Kolodner, R.D.3
  • 40
    • 0037414642 scopus 로고    scopus 로고
    • Trnasfer of the MSH2-MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA
    • Lau PJ Kolodner RD 2003 Trnasfer of the MSH2-MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA. J Biol Chem 278, 14 17.
    • (2003) J Biol Chem , vol.278 , pp. 14-17
    • Lau, P.J.1    Kolodner, R.D.2
  • 41
    • 0345276522 scopus 로고    scopus 로고
    • Mechanism of 5′ directed excision in human mismatch repair
    • Genschel J Modrich P 2003 Mechanism of 5′ directed excision in human mismatch repair. Mol Cell 12, 1077 1086.
    • (2003) Mol Cell , vol.12 , pp. 1077-1086
    • Genschel, J.1    Modrich, P.2
  • 42
    • 2342425404 scopus 로고    scopus 로고
    • Differential requirement for proliferating cell nuclear antigen in 5′-and 3′ nick-directed excision in human mismatch repair
    • Guo S Presnell SR Yuan F Zhang Y Gu L Li GM 2004 Differential requirement for proliferating cell nuclear antigen in 5′-and 3′ nick-directed excision in human mismatch repair. J Biol Chem 279, 16912 16917.
    • (2004) J Biol Chem , vol.279 , pp. 16912-16917
    • Guo, S.1    Presnell, S.R.2    Yuan, F.3    Zhang, Y.4    Gu, L.5    Li, G.M.6
  • 43
    • 0031953114 scopus 로고    scopus 로고
    • The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein a is required for DNA replication and mismatch repair but not for nucleotide excision repair
    • Lin YL Shivji MKK Chen C Kolodner R Wood RD Dutta A 1998 The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair. J Biol Chem 273, 1453 1461.
    • (1998) J Biol Chem , vol.273 , pp. 1453-1461
    • Lin, Y.L.1    Shivji, M.K.K.2    Chen, C.3    Kolodner, R.4    Wood, R.D.5    Dutta, A.6
  • 44
    • 0036121372 scopus 로고    scopus 로고
    • Partial reconstitution of human DNA mismatch repair in vitro: Characterization of the role of human replication protein a
    • Ramilo C Gu L Guo S Zhang X Patrick SM Turchi JJ Li GM 2002 Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A. Mol Cell Biol 22, 2037 2046.
    • (2002) Mol Cell Biol , vol.22 , pp. 2037-2046
    • Ramilo, C.1    Gu, L.2    Guo, S.3    Zhang, X.4    Patrick, S.M.5    Turchi, J.J.6    Li, G.M.7
  • 45
    • 0032588388 scopus 로고    scopus 로고
    • The 3′→5′ exonucleases of DNA polymerases δ and ε and the 5′→3′ exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae
    • Tran HT Gordenin DA Resnick MA 1999 The 3′→5′ exonucleases of DNA polymerases δ and ε and the 5′→ 3′ exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae. Mol Cell Biol 19, 2000 2007.
    • (1999) Mol Cell Biol , vol.19 , pp. 2000-2007
    • Tran, H.T.1    Gordenin, D.A.2    Resnick, M.A.3
  • 46
    • 0027212371 scopus 로고
    • A 5′→3′ exonuclease from Saccharomyces cerevisiae is required for in vitro recombination between linear DNA molecules with overlapping homology
    • Huang KN Symington LS 1993 A 5′→3′ exonuclease from Saccharomyces cerevisiae is required for in vitro recombination between linear DNA molecules with overlapping homology. Mol Cell Biol 13, 3125 3134.
    • (1993) Mol Cell Biol , vol.13 , pp. 3125-3134
    • Huang, K.N.1    Symington, L.S.2
  • 47
    • 0035859816 scopus 로고    scopus 로고
    • Interactions of Exo1p with components of MutLα in Saccharomyces cerevisiae
    • Tran PT Simon JA Liskay RM 2001 Interactions of Exo1p with components of MutLα in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 98, 9760 9765.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9760-9765
    • Tran, P.T.1    Simon, J.A.2    Liskay, R.M.3
  • 48
    • 0037066720 scopus 로고    scopus 로고
    • Human exonuclease I is required for 5′- and 3′ mismatch repair
    • Genschel J Bazemore LR Modrich P 2002 Human exonuclease I is required for 5′- and 3′ mismatch repair. J Biol Chem 277, 13302 13311.
    • (2002) J Biol Chem , vol.277 , pp. 13302-13311
    • Genschel, J.1    Bazemore, L.R.2    Modrich, P.3
  • 50
    • 0030935386 scopus 로고    scopus 로고
    • DNA polymerase δ is required for human mismatch repair in vitro
    • Longley MJ Pierce AJ Modrich P 1997 DNA polymerase δ is required for human mismatch repair in vitro. J Biol Chem 272, 10917 10921.
    • (1997) J Biol Chem , vol.272 , pp. 10917-10921
    • Longley, M.J.1    Pierce, A.J.2    Modrich, P.3
  • 51
    • 0032029995 scopus 로고    scopus 로고
    • ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
    • Gu L Hong Y McCulloch S Watanabe H Li GM 1998 ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair. Nucleic Acids Res 26, 1173 1178.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1173-1178
    • Gu, L.1    Hong, Y.2    McCulloch, S.3    Watanabe, H.4    Li, G.M.5
  • 52
    • 0027502938 scopus 로고
    • Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage
    • Branch P Aquilina G Bignami M Karran P 1993 Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage. Nature 362, 652 654.
    • (1993) Nature , vol.362 , pp. 652-654
    • Branch, P.1    Aquilina, G.2    Bignami, M.3    Karran, P.4
  • 53
    • 0031906084 scopus 로고    scopus 로고
    • The role of DNA mismatch repair in drug resistance
    • Fink D Aebi S Howell SB 1998 The role of DNA mismatch repair in drug resistance. Clin Cancer Res 4, 1 6.
    • (1998) Clin Cancer Res , vol.4 , pp. 1-6
    • Fink, D.1    Aebi, S.2    Howell, S.B.3
  • 54
  • 55
    • 0031426561 scopus 로고    scopus 로고
    • Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting
    • Tominaga Y Tsuzuki T Shiraishi A Kawate H Sekiguchi M 1997 Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting. Carcinogenesis 18, 889 896.
    • (1997) Carcinogenesis , vol.18 , pp. 889-896
    • Tominaga, Y.1    Tsuzuki, T.2    Shiraishi, A.3    Kawate, H.4    Sekiguchi, M.5
  • 56
    • 0029972806 scopus 로고    scopus 로고
    • P53: Puzzle and paradigm
    • Ko LJ Prives C 1996 P53: puzzle and paradigm. Genes Dev 10, 1054 1072.
    • (1996) Genes Dev , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 57
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: A link between cancer genetics and chemotherapy
    • Johnstone RW Ruefli AA Lowe SW 2002 Apoptosis: a link between cancer genetics and chemotherapy. Cell 108, 153 164.
    • (2002) Cell , vol.108 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 59
    • 0031564954 scopus 로고    scopus 로고
    • P73 is a human p53-related protein that can induce apoptosis
    • Jost C Marin M Kaelin W 1997 p73 is a human p53-related protein that can induce apoptosis. Nature 389, 191 194.
    • (1997) Nature , vol.389 , pp. 191-194
    • Jost, C.1    Marin, M.2    Kaelin, W.3
  • 60
    • 0033607055 scopus 로고    scopus 로고
    • HMutSα and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
    • Duckett DR Bronstein SM Taya Y Modrich P 1999 hMutSα and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage. Proc Natl Acad Sci USA 96, 12384 12388.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12384-12388
    • Duckett, D.R.1    Bronstein, S.M.2    Taya, Y.3    Modrich, P.4
  • 61
    • 0037414342 scopus 로고    scopus 로고
    • Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation
    • Peters AC Young LC Maeda T Tron VA Andrew SE 2003 Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation. DNA Repair (Amsterdam) 2, 427 435.
    • (2003) DNA Repair (Amsterdam) , vol.2 , pp. 427-435
    • Peters, A.C.1    Young, L.C.2    Maeda, T.3    Tron, V.A.4    Andrew, S.E.5
  • 63
    • 0344284564 scopus 로고    scopus 로고
    • Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
    • Shimodaira H Yamashita AY Kolodner RD Wang JYJ 2003 Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc Natl Acad Sci USA 100, 2420 2425.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2420-2425
    • Shimodaira, H.1    Yamashita, A.Y.2    Kolodner, R.D.3    Wang, J.Y.J.4
  • 64
    • 0027292234 scopus 로고
    • An alkylation-tolerant, mutator human cell line is deficient in strandspecific mismatch repair
    • Kat A Thilly WG Fang WH Longley MJ Li GM Modrich P 1993 An alkylation-tolerant, mutator human cell line is deficient in strandspecific mismatch repair. Proc Natl Acad Sci USA 90, 6424 6428.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6424-6428
    • Kat, A.1    Thilly, W.G.2    Fang, W.H.3    Longley, M.J.4    Li, G.M.5    Modrich, P.6
  • 67
    • 2442670292 scopus 로고    scopus 로고
    • Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase
    • Stojic L Mojas N Cejka P Di Pietro M Ferrari S Marra G Jiricny J 2004 Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. Genes Dev 18, 1331 1344.
    • (2004) Genes Dev , vol.18 , pp. 1331-1344
    • Stojic, L.1    Mojas, N.2    Cejka, P.3    Di Pietro, M.4    Ferrari, S.5    Marra, G.6    Jiricny, J.7
  • 68
    • 14844331767 scopus 로고    scopus 로고
    • Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2
    • Adamson AW Beardsley DI Kim W Gao Y Baskaran R Brown KD 2005 Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. Mol Biol Cell 16, 1513 1526.
    • (2005) Mol Biol Cell , vol.16 , pp. 1513-1526
    • Adamson, A.W.1    Beardsley, D.I.2    Kim, W.3    Gao, Y.4    Baskaran, R.5    Brown, K.D.6
  • 69
    • 0242663968 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents
    • Hirose Y Katayama M Stokoe D Kogan DAH Berger MS Pieper RO 2003 The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents. Mol Cell Biol 23, 8306 8315.
    • (2003) Mol Cell Biol , vol.23 , pp. 8306-8315
    • Hirose, Y.1    Katayama, M.2    Stokoe, D.3    Kogan, D.A.H.4    Berger, M.S.5    Pieper, R.O.6
  • 71
    • 0347364654 scopus 로고    scopus 로고
    • MSH2 and ATR form a signaling module and regulate two brnaches of the damage response to DNA methylation
    • Wang Y Qin J 2003 MSH2 and ATR form a signaling module and regulate two brnaches of the damage response to DNA methylation. Proc Natl Acad Sci USA 100, 15387 15392.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15387-15392
    • Wang, Y.1    Qin, J.2
  • 72
    • 4143051517 scopus 로고    scopus 로고
    • ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background
    • Fang Y Tsao CC Goodman BK Furumai R Tirado CA Abraham RT Wang XF 2004 ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background. EMBO J 23, 3164 3174.
    • (2004) EMBO J , vol.23 , pp. 3164-3174
    • Fang, Y.1    Tsao, C.C.2    Goodman, B.K.3    Furumai, R.4    Tirado, C.A.5    Abraham, R.T.6    Wang, X.F.7
  • 73
    • 0034655991 scopus 로고    scopus 로고
    • BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
    • Wang Y Cortez D Yazdi P Neff N Elledge SJ Qin J 2000 BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 14, 927 939.
    • (2000) Genes Dev , vol.14 , pp. 927-939
    • Wang, Y.1    Cortez, D.2    Yazdi, P.3    Neff, N.4    Elledge, S.J.5    Qin, J.6
  • 74
    • 16344393332 scopus 로고    scopus 로고
    • Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements
    • Chen J Sadowski I 2005 Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements. Proc Natl Acad Sci USA 102, 4813 4818.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4813-4818
    • Chen, J.1    Sadowski, I.2
  • 75
    • 3042791562 scopus 로고    scopus 로고
    • ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage
    • Luo Y Lin F Lin W 2004 ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage. Mol Cell Biol 24, 6430 6444.
    • (2004) Mol Cell Biol , vol.24 , pp. 6430-6444
    • Luo, Y.1    Lin, F.2    Lin, W.3
  • 76
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa S 1983 Somatic generation of antibody diversity. Nature 302, 575 581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 78
    • 0032127804 scopus 로고    scopus 로고
    • Hot spot focusing of somatic hypermutation in MSH-deficient mice suggests two stages of mutational targeting
    • Rada C Ehrenstein MR Neuberger MS Milstein C 1998 Hot spot focusing of somatic hypermutation in MSH-deficient mice suggests two stages of mutational targeting. Immunity 9, 135 141.
    • (1998) Immunity , vol.9 , pp. 135-141
    • Rada, C.1    Ehrenstein, M.R.2    Neuberger, M.S.3    Milstein, C.4
  • 79
    • 0034614916 scopus 로고    scopus 로고
    • Somatic mutation in MSH3, MSH6, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern
    • Wiesendanger M Kneitz B Edelmann W Scharff MD 2000 Somatic mutation in MSH3, MSH6, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. J Exp Med 191, 579 584.
    • (2000) J Exp Med , vol.191 , pp. 579-584
    • Wiesendanger, M.1    Kneitz, B.2    Edelmann, W.3    Scharff, M.D.4
  • 80
    • 3142674907 scopus 로고    scopus 로고
    • Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification
    • Li Z Scherer SJ Ronai D Ussel MDI Peled JU Bardwell PD Zhuang M Lee K Martin A Edelmann W et al. 2004 Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. J Exp Med 200, 47 59.
    • (2004) J Exp Med , vol.200 , pp. 47-59
    • Li, Z.1    Scherer, S.J.2    Ronai, D.3    Ussel, M.D.I.4    Peled, J.U.5    Bardwell, P.D.6    Zhuang, M.7    Lee, K.8    Martin, A.9    Edelmann, W.10
  • 81
    • 0142250270 scopus 로고    scopus 로고
    • Msh2 ATPase activity is essential for somatic hypermutation at A-T basepairs and for efficient class switch recombination
    • Martin A Li Z Lin D Bardwell PD Iglesias-Ussel MD Edelmann W Scharff MD 2003 Msh2 ATPase activity is essential for somatic hypermutation at A-T basepairs and for efficient class switch recombination. J Exp Med 198, 1171 1178.
    • (2003) J Exp Med , vol.198 , pp. 1171-1178
    • Martin, A.1    Li, Z.2    Lin, D.3    Bardwell, P.D.4    Iglesias-Ussel, M.D.5    Edelmann, W.6    Scharff, M.D.7
  • 82
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M Kinoshita K Fagarasan S Yamada S Shinkai Y Honjo T 2000 Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553 563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 83
    • 0037926476 scopus 로고    scopus 로고
    • Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
    • Pham P Bransteitter R Petruska J Goodman M 2003 Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation. Nature 424, 103 107.
    • (2003) Nature , vol.424 , pp. 103-107
    • Pham, P.1    Bransteitter, R.2    Petruska, J.3    Goodman, M.4
  • 84
    • 0031918097 scopus 로고    scopus 로고
    • Progress in understanding the mechanism and consequences of somatic hypermutation
    • Storb U 1998 Progress in understanding the mechanism and consequences of somatic hypermutation. Immunol Rev 162, 5 11.
    • (1998) Immunol Rev , vol.162 , pp. 5-11
    • Storb, U.1
  • 85
    • 0037388165 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of Rnase
    • Bransteitter R Pham P Shcarff MD Goodman MF 2003 Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of Rnase. Proc Natl Acad Sci USA 100, 4102 4107.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4102-4107
    • Bransteitter, R.1    Pham, P.2    Shcarff, M.D.3    Goodman, M.F.4
  • 86
    • 0037452080 scopus 로고    scopus 로고
    • Transcription-targeted DNA deamination by the AID antibody diversification enzyme
    • Chaudhuri J Tian M Khuong C Chua K Pinaud E Alt FW 2003 Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature 422, 726 730.
    • (2003) Nature , vol.422 , pp. 726-730
    • Chaudhuri, J.1    Tian, M.2    Khuong, C.3    Chua, K.4    Pinaud, E.5    Alt, F.W.6
  • 87
    • 0035377269 scopus 로고    scopus 로고
    • DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
    • Zeng X Winter DB Kasmer C Kraemer KH Lehmann AR Gearhart PJ 2001 DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Nat Immunol 2, 537 541.
    • (2001) Nat Immunol , vol.2 , pp. 537-541
    • Zeng, X.1    Winter, D.B.2    Kasmer, C.3    Kraemer, K.H.4    Lehmann, A.R.5    Gearhart, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.