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Volumn 15, Issue 5, 2006, Pages 507-517

The potential of clusterin inhibiting antisense oligodeoxynucleotide therapy for prostate cancer

Author keywords

Antisense olgionucleotide; Clusterin; Prostate cancer

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; ANTISENSE OLIGODEOXYNUCLEOTIDE; CISPLATIN; CLUSTERIN; DOCETAXEL; GEMCITABINE; HEAT SHOCK PROTEIN 27; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIVER ENZYME; MITOXANTRONE; OGX 011; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PACLITAXEL; PREDNISONE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MYB; PROTEIN P53; SMALL INTERFERING RNA; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 5; UNCLASSIFIED DRUG;

EID: 33646456336     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.15.5.507     Document Type: Review
Times cited : (30)

References (113)
  • 1
    • 22144484150 scopus 로고    scopus 로고
    • Androgen deprivation therapy for prostate cancer
    • SHARIFI N, GULLEY JL, DAHUT WL: Androgen deprivation therapy for prostate cancer. J. Am. Med. Assoc. (2005) 294:238-244.
    • (2005) J. Am. Med. Assoc. , vol.294 , pp. 238-244
    • Sharifi, N.1    Gulley, J.L.2    Dahut, W.L.3
  • 3
    • 0034817278 scopus 로고    scopus 로고
    • Long-term biochemical disease-free and cancer-specific survival following anatomic radical retropubic prostatectomy. The 15-year Johns Hopkins experience
    • HAN M, PARTIN AW, POUND CR, EPSTEIN JI, WALSH PC: Long-term biochemical disease-free and cancer-specific survival following anatomic radical retropubic prostatectomy. The 15-year Johns Hopkins experience. Urol. Clin. North. Am. (2001) 28:555-565.
    • (2001) Urol. Clin. North. Am. , vol.28 , pp. 555-565
    • Han, M.1    Partin, A.W.2    Pound, C.R.3    Epstein, J.I.4    Walsh, P.C.5
  • 4
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • TANNOCK IF, DE WIT R, BERRY WR et al.: Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N. Engl. J. Med. (2004) 351:1502-1512.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1502-1512
    • Tannock, I.F.1    De Wit, R.2    Berry, W.R.3
  • 5
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • PETRYLAK DP, TANGEN CM, HUSSAIN MH et al: Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N. Engl. J. Med. (2004) 351:1513-1520.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 1513-1520
    • Petrylak, D.P.1    Tangen, C.M.2    Hussain, M.H.3
  • 6
    • 15844429706 scopus 로고    scopus 로고
    • Mechanisms of the development of androgen independence in prostate cancer
    • SO A, GLEAVE M, HURTADO-COL A, NELSON C: Mechanisms of the development of androgen independence in prostate cancer. World J. Urol. (2005) 23:1-9.
    • (2005) World J. Urol. , vol.23 , pp. 1-9
    • So, A.1    Gleave, M.2    Hurtado-col, A.3    Nelson, C.4
  • 7
    • 0033215472 scopus 로고    scopus 로고
    • Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process
    • CRAFT N, CHHOR C, TRAN C et al.: Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process. Cancer Res. (1999) 59:5030-5036.
    • (1999) Cancer Res. , vol.59 , pp. 5030-5036
    • Craft, N.1    Chhor, C.2    Tran, C.3
  • 8
    • 0030841919 scopus 로고    scopus 로고
    • Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and Ap- l /c-Jun in the human prostate cancer cell line LNCaP
    • SATO N, SADAR MD, BRUCHOVSKY N et al: Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and Ap- l/c-Jun in the human prostate cancer cell line LNCaP. J. Biol. Chem. (1997) 272:17485-17494.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17485-17494
    • Sato, N.1    Sadar, M.D.2    Bruchovsky, N.3
  • 9
    • 0036510548 scopus 로고    scopus 로고
    • Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways
    • UEDA T, BRUCHOVSKY N, SADAR MD: Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways. J. Biol. Chem. (2002) 277:7076-7085.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7076-7085
    • Ueda, T.1    Bruchovsky, N.2    Sadar, M.D.3
  • 10
    • 12144288184 scopus 로고    scopus 로고
    • Osteoblast-derived factors induce androgen-independent proliferation and expression of prostate-specific antigen in human prostate cancer cells
    • BLASZCZYK N, MASRI BA, MAWJI NR et al.: Osteoblast-derived factors induce androgen-independent proliferation and expression of prostate-specific antigen in human prostate cancer cells. Clin. Cancer Res. (2004) 10:1860-1869.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1860-1869
    • Blaszczyk, N.1    Masri, B.A.2    Mawji, N.R.3
  • 11
    • 10744227995 scopus 로고    scopus 로고
    • Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases
    • UEHARA H, KIM SJ, KARASHIMA T et al.: Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. J. Natl. Cancer Inst. (2003) 95:458-470.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 458-470
    • Uehara, H.1    Kim, S.J.2    Karashima, T.3
  • 12
    • 0033022342 scopus 로고    scopus 로고
    • A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
    • CRAFT N, SHOSTAK Y, CAREY M, SAWYERS CL: A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat. Med. (1999) 5:280-285.
    • (1999) Nat. Med. , vol.5 , pp. 280-285
    • Craft, N.1    Shostak, Y.2    Carey, M.3    Sawyers, C.L.4
  • 13
    • 0033567003 scopus 로고    scopus 로고
    • Antisense Bcl-2 oligodeoxynucleotides inhibit progression to androgen-independence after castration in the Shionogi tumor model
    • MIYAKE H, TOLCHER A, GLEAVE ME: Antisense Bcl-2 oligodeoxynucleotides inhibit progression to androgen-independence after castration in the Shionogi tumor model. Cancer Res. (1999) 59:4030-4034.
    • (1999) Cancer Res. , vol.59 , pp. 4030-4034
    • Miyake, H.1    Tolcher, A.2    Gleave, M.E.3
  • 14
    • 0033978525 scopus 로고    scopus 로고
    • Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer
    • MIYAKE H, NELSON C, RENNIE PS, GLEAVE ME: Testosterone-repressed prostate message-2 is an antiapoptotic gene involved in progression to androgen independence in prostate cancer. Cancer Res. (2000) 60:170-176.
    • (2000) Cancer Res. , vol.60 , pp. 170-176
    • Miyake, H.1    Nelson, C.2    Rennie, P.S.3    Gleave, M.E.4
  • 15
    • 0034213320 scopus 로고    scopus 로고
    • Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models
    • MIYAKE H, POLLAK M, GLEAVE ME: Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models. Cancer Res. (2000) 60:3058-3064.
    • (2000) Cancer Res. , vol.60 , pp. 3058-3064
    • Miyake, H.1    Pollak, M.2    Gleave, M.E.3
  • 16
    • 0038756444 scopus 로고    scopus 로고
    • Castration-induced increase in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors
    • KIYAMA S, MORRISON K, ZELLWEGER T et al.: Castration-induced increase in insulin-like growth factor-binding protein 2 promotes proliferation of androgen-independent human prostate LNCaP tumors. Cancer Res. (2003) 63:3575-3584.
    • (2003) Cancer Res. , vol.63 , pp. 3575-3584
    • Kiyama, S.1    Morrison, K.2    Zellweger, T.3
  • 17
    • 4644237335 scopus 로고    scopus 로고
    • Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer
    • ROCCHI P, SO A, KOJIMA S et al.: Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer. Cancer Res. (2004) 64:6595-6602.
    • (2004) Cancer Res. , vol.64 , pp. 6595-6602
    • Rocchi, P.1    So, A.2    Kojima, S.3
  • 18
    • 0027093255 scopus 로고
    • Expression of the protooncogene Bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
    • McDONNELL TJ, TRONCOSO P, BRISBAY SM et al.: Expression of the protooncogene Bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res. (1992) 52:6940-6944.
    • (1992) Cancer Res. , vol.52 , pp. 6940-6944
    • Mcdonnell, T.J.1    Troncoso, P.2    Brisbay, S.M.3
  • 19
    • 0033565216 scopus 로고    scopus 로고
    • Castration-induced apoptosis of androgen-dependent Shionogi carcinoma is associated with increased expression of genes encoding insulin-like growth factor binding proteins
    • NICKERSON T, MIYAKE H, GLEAVE ME, POLLAK M: Castration-induced apoptosis of androgen-dependent Shionogi carcinoma is associated with increased expression of genes encoding insulin-like growth factor binding proteins. Cancer Res. (1999) 59:3392-3395.
    • (1999) Cancer Res. , vol.59 , pp. 3392-3395
    • Nickerson, T.1    Miyake, H.2    Gleave, M.E.3    Pollak, M.4
  • 20
    • 0034659691 scopus 로고    scopus 로고
    • Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense Bcl-xL and antisense Bcl-2 oligodeoxynucleotides plus taxol after castration in the Shionogi tumor model
    • MIYAKE H, MONIA BP, GLEAVE ME: Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense Bcl-xL and antisense Bcl-2 oligodeoxynucleotides plus taxol after castration in the Shionogi tumor model. Int. J. Cancer (2000) 86:855-862.
    • (2000) Int. J. Cancer , vol.86 , pp. 855-862
    • Miyake, H.1    Monia, B.P.2    Gleave, M.E.3
  • 21
    • 0037083472 scopus 로고    scopus 로고
    • Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy
    • JULY LV, AKBARI M, ZELLWEGER T, JONES EC, GOLDENBERG SL, GLEAVE ME: Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy. Prostate (2002) 50:179-188.
    • (2002) Prostate , vol.50 , pp. 179-188
    • July, L.V.1    Akbari, M.2    Zellweger, T.3    Jones, E.C.4    Goldenberg, S.L.5    Gleave, M.E.6
  • 22
    • 0034455310 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor binding protein-5 helps accelerate progression to androgen-independence in the human prostate LNCaP tumor model through activation of phosphatidylinositol 3′-kinase pathway
    • MIYAKE H, NELSON C, RENNIE PS, GLEAVE ME. Overexpression of insulin-like growth factor binding protein-5 helps accelerate progression to androgen-independence in the human prostate LNCaP tumor model through activation of phosphatidylinositol 3′-kinase pathway. Endocrinology (2000) 141:2257-2265.
    • (2000) Endocrinology , vol.141 , pp. 2257-2265
    • Miyake, H.1    Nelson, C.2    Rennie, P.S.3    Gleave, M.E.4
  • 23
    • 28044468839 scopus 로고    scopus 로고
    • A novel bispecific antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells
    • YAMANAKA K, ROCCHI P, MIYAKE H et al.: A novel bispecific antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells. Mol. Cancer Ther. (2005) 4:1688-1698.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 1688-1698
    • Yamanaka, K.1    Rocchi, P.2    Miyake, H.3
  • 24
    • 0029124742 scopus 로고
    • Clusterin: Physiologic and pathophysiologic considerations
    • ROSENBERG ME, SILKENSEN J: Clusterin: physiologic and pathophysiologic considerations. Int. J. Biochem. Cell Biol. (1995) 27:633-645.
    • (1995) Int. J. Biochem. Cell Biol. , vol.27 , pp. 633-645
    • Rosenberg, M.E.1    Silkensen, J.2
  • 25
    • 0036829661 scopus 로고    scopus 로고
    • Clusterin/apolipoprotein J in human ageing and cancer
    • TROUGAKOS IP, GONOS ES: Clusterin/apolipoprotein J in human ageing and cancer. Int. J. Biochem. Cell Biol. (2002) 34:1430-1448.
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 1430-1448
    • Trougakos, I.P.1    Gonos, E.S.2
  • 26
    • 0034722899 scopus 로고    scopus 로고
    • Potential roles of antisense technology in cancer chemotherapy
    • CROOKE ST: Potential roles of antisense technology in cancer chemotherapy. Oncogene (2000) 19:6651-6659.
    • (2000) Oncogene , vol.19 , pp. 6651-6659
    • Crooke, S.T.1
  • 27
    • 0034026142 scopus 로고    scopus 로고
    • Antisense approaches enter the clinic
    • KHURI FR, KURIE JM: Antisense approaches enter the clinic. Clin. Cancer Res. (2000) 6:1607-1610.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1607-1610
    • Khuri, F.R.1    Kurie, J.M.2
  • 28
  • 29
    • 0032970584 scopus 로고    scopus 로고
    • Antisense oligonucleotiude therapeutics
    • BENNETT CF: Antisense oligonucleotiude therapeutics. Expert Opin. Investig. Drugs (1999) 8:237-253.
    • (1999) Expert Opin. Investig. Drugs , vol.8 , pp. 237-253
    • Bennett, C.F.1
  • 30
    • 0025887020 scopus 로고
    • SGP-2 expression as a genetic marker of progressive cellular pathology in experimental hydronephrosis
    • CONNOR J, BUTTYAN R, OLSSON CA, D'AGATI V, O'TOOLE K, SAWCZUK IS: SGP-2 expression as a genetic marker of progressive cellular pathology in experimental hydronephrosis. Kidney Int. (1991) 39:1098-1103.
    • (1991) Kidney Int. , vol.39 , pp. 1098-1103
    • Connor, J.1    Buttyan, R.2    Olsson, C.A.3    D'agati, V.4    O'toole, K.5    Sawczuk, I.S.6
  • 31
    • 0026088670 scopus 로고
    • Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation
    • KYPRIANOU N, ENGLISH HF, DAVIDSON NE, ISSACS JT. Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation. Cancer Res. (1991) 51:162-166.
    • (1991) Cancer Res. , vol.51 , pp. 162-166
    • Kyprianou, N.1    English, H.F.2    Davidson, N.E.3    Issacs, J.T.4
  • 32
    • 0025833074 scopus 로고
    • Prostatic ductal system in rats: Regional variation in localization of an androgen-repressed gene product, sulfated glycoprotein-2
    • SENSIBAR JA, GRISWOLD MD, SYLVESTER SR et al: Prostatic ductal system in rats: regional variation in localization of an androgen-repressed gene product, sulfated glycoprotein-2. Endocrinology (1991) 128:2091-2102.
    • (1991) Endocrinology , vol.128 , pp. 2091-2102
    • Sensibar, J.A.1    Griswold, M.D.2    Sylvester, S.R.3
  • 33
    • 0022627063 scopus 로고
    • Androgen-repressed messages in the rat ventral prostate
    • MONTPEIT ML, LAWLESS KR, TENNISWOOD M: Androgen-repressed messages in the rat ventral prostate. Prostate (1986) 8:25-36.
    • (1986) Prostate , vol.8 , pp. 25-36
    • Montpeit, M.L.1    Lawless, K.R.2    Tenniswood, M.3
  • 35
    • 0025298231 scopus 로고
    • Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation
    • KYPRIANOU N, ENGLISH HF, ISAACS JT: Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation. Cancer Res. (1990) 50:3748-3753.
    • (1990) Cancer Res. , vol.50 , pp. 3748-3753
    • Kyprianou, N.1    English, H.F.2    Isaacs, J.T.3
  • 36
    • 0030064916 scopus 로고    scopus 로고
    • A ribonucleotide reductase inhibitor, MDL 101,731, induces apoptosis and elevates TRPM-2 mRNA levels in human prostate tumor xenografts
    • WRIGHT PS, CROSS-DOERSON D, TH'NG JP et al: A ribonucleotide reductase inhibitor, MDL 101,731, induces apoptosis and elevates TRPM-2 mRNA levels in human prostate tumor xenografts. Exp. Cell Res. (1996) 222:54-60.
    • (1996) Exp. Cell Res. , vol.222 , pp. 54-60
    • Wright, P.S.1    Cross-doerson, D.2    Th'ng, J.P.3
  • 37
    • 0033589283 scopus 로고    scopus 로고
    • Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue arrays
    • BUBENDORF L, KOLMER M, KONONEN J et al.: Hormone therapy failure in human prostate cancer: analysis by complementary DNA and tissue arrays. J. Natl. Cancer Inst. (1999) 91:1758-1764.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1758-1764
    • Bubendorf, L.1    Kolmer, M.2    Kononen, J.3
  • 38
    • 0034192382 scopus 로고    scopus 로고
    • Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models
    • MIYAKE H, NELSON C, RENNIE PS, GLEAVE ME: Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models. Cancer Res. (2000) 60:2547-2554.
    • (2000) Cancer Res. , vol.60 , pp. 2547-2554
    • Miyake, H.1    Nelson, C.2    Rennie, P.S.3    Gleave, M.E.4
  • 39
    • 0034112089 scopus 로고    scopus 로고
    • Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo
    • MIYAKE H, CHI KN, GLEAVE ME: Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo. Clin. Cancer Res. (2000) 6:1655-1663.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1655-1663
    • Miyake, H.1    Chi, K.N.2    Gleave, M.E.3
  • 40
    • 0036796026 scopus 로고    scopus 로고
    • Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin
    • ZELLWEGER T, CHI K, MIYAKE H et al.: Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin. Clin. Cancer Res. (2002) 8:3276-3284.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3276-3284
    • Zellweger, T.1    Chi, K.2    Miyake, H.3
  • 41
    • 0042912014 scopus 로고    scopus 로고
    • Overexpression of the cytoprotective protein clusterin decreases radiosensitivity in the human LNCaP prostate tumor model
    • ZELLWEGER T, KIYAMA S, CHI K et al: Overexpression of the cytoprotective protein clusterin decreases radiosensitivity in the human LNCaP prostate tumor model. BJU Int. (2003) 92:463-469.
    • (2003) BJU Int. , vol.92 , pp. 463-469
    • Zellweger, T.1    Kiyama, S.2    Chi, K.3
  • 42
    • 9444288705 scopus 로고    scopus 로고
    • Protection of androgen-dependent human prostate cancer cells from oxidative stress-induced DNA damage by overexpression of cluterin and its modulation by androgen
    • MIYAKE H, HARA I, GLEAVE ME, ETO H: Protection of androgen-dependent human prostate cancer cells from oxidative stress-induced DNA damage by overexpression of cluterin and its modulation by androgen. Prostate (2004) 61:318-323.
    • (2004) Prostate , vol.61 , pp. 318-323
    • Miyake, H.1    Hara, I.2    Gleave, M.E.3    Eto, H.4
  • 43
    • 14844293486 scopus 로고    scopus 로고
    • Synergistic antitumor effect of combined use of adenoviral-mediated p53 gene transfer and antisense oligodeoxynucleotide targeting clusterin gene in an androgen-independent human prostate cancer model
    • YAMANAKA K, GLEAVE ME, HARA I, MURAMAKI M, MIYAKE H: Synergistic antitumor effect of combined use of adenoviral-mediated p53 gene transfer and antisense oligodeoxynucleotide targeting clusterin gene in an androgen-independent human prostate cancer model. Mol. Cancer Ther. (2005) 4:187-195.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 187-195
    • Yamanaka, K.1    Gleave, M.E.2    Hara, I.3    Muramaki, M.4    Miyake, H.5
  • 44
    • 27744552075 scopus 로고    scopus 로고
    • Enhanced expression of the secreted form of clusterin following neoadjuvant hormonal therapy as a prognostic predictor in patients undergoing radical prostatectomy for prostate cancer
    • MIYAKE H, YAMANAKA K, MURAMAKI M, KURAHASHI T, GLEAVE M, HARA I: Enhanced expression of the secreted form of clusterin following neoadjuvant hormonal therapy as a prognostic predictor in patients undergoing radical prostatectomy for prostate cancer. Oncol. Rep. (2005) 14:1371-1375.
    • (2005) Oncol. Rep. , vol.14 , pp. 1371-1375
    • Miyake, H.1    Yamanaka, K.2    Muramaki, M.3    Kurahashi, T.4    Gleave, M.5    Hara, I.6
  • 45
    • 0030843011 scopus 로고    scopus 로고
    • Intracellular levels of'SGP-2 (clusterin) correlate with tumor grade in prostate cancer
    • STEINBERG J, OYASU R, LANG S et al.: Intracellular levels of'SGP-2 (clusterin) correlate with tumor grade in prostate cancer. Clin. Cancer Res. (1997) 3:1707-1711.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 1707-1711
    • Steinberg, J.1    Oyasu, R.2    Lang, S.3
  • 46
    • 15944373057 scopus 로고    scopus 로고
    • Clusterin as a possible predictor for biochemical recurrence of prostate cancer following radical prostatectomy with intermediate Gleason score: A preliminary report
    • PINS MR, FIADJOE JE, KORLEY F et al.: Clusterin as a possible predictor for biochemical recurrence of prostate cancer following radical prostatectomy with intermediate Gleason score: a preliminary report. Prostate Cancer Prostatic Dis. (2004) 7:243-248.
    • (2004) Prostate Cancer Prostatic Dis. , vol.7 , pp. 243-248
    • Pins, M.R.1    Fiadjoe, J.E.2    Korley, F.3
  • 47
    • 0031748528 scopus 로고    scopus 로고
    • Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties
    • SCHWOCHAU GB, NATH KA, ROSENBERG ME: Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties. Kidney Int. (1998) 53:1647-1653.
    • (1998) Kidney Int. , vol.53 , pp. 1647-1653
    • Schwochau, G.B.1    Nath, K.A.2    Rosenberg, M.E.3
  • 48
    • 0028210028 scopus 로고
    • Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death
    • FRENCH LE, WOHLWEND A, SAPPINO AF, TSCHOPP J, SCHIFFERLI JA: Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death. J. Clin. Investig. (1994) 93:877-884.
    • (1994) J. Clin. Investig. , vol.93 , pp. 877-884
    • French, L.E.1    Wohlwend, A.2    Sappino, A.F.3    Tschopp, J.4    Schifferli, J.A.5
  • 49
    • 0026469891 scopus 로고
    • Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus
    • FRENCH LE, SAPPINO AP, TSCHOPP J, SCHIFFERLI JA: Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus. J. Clin. Investig. (1992) 90:1919-1925.
    • (1992) J. Clin. Investig. , vol.90 , pp. 1919-1925
    • French, L.E.1    Sappino, A.P.2    Tschopp, J.3    Schifferli, J.A.4
  • 51
    • 2342566706 scopus 로고    scopus 로고
    • Repression of IR-inducible clusterin expression by the p53 tumour suppressor protein
    • CRISWELL T, KLOKOV D, BEMAN M, LAVIK JP, BOOTHMAN DA: Repression of IR-inducible clusterin expression by the p53 tumour suppressor protein. Cancer Biol. Ther. (2003) 2:372-380.
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 372-380
    • Criswell, T.1    Klokov, D.2    Beman, M.3    Lavik, J.P.4    Boothman, D.A.5
  • 52
    • 0034647738 scopus 로고    scopus 로고
    • Direct transactivation of the antiapoptotic gene apolipoprotein J (clusterin) by B-MYB
    • CERVELLERA M, RASCHELLA G, SANTILLI G et al.: Direct transactivation of the antiapoptotic gene apolipoprotein J (clusterin) by B-MYB. J. Biol. Chem. (2000) 275:21055-21060.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21055-21060
    • Cervellera, M.1    Raschella, G.2    Santilli, G.3
  • 53
    • 0141643351 scopus 로고    scopus 로고
    • Essential requirement of apolipoprotein J (clusterin) signaling for IκB expression and regulation of NF-κB activity
    • SANKILL G, ARONOW BJ, SALA A: Essential requirement of apolipoprotein J (clusterin) signaling for IκB expression and regulation of NF-κB activity. J. Biol. Chem. (2003) 278:38214-38219.
    • (2003) J. Biol. Chem. , vol.278 , pp. 38214-38219
    • Sankill, G.1    Aronow, B.J.2    Sala, A.3
  • 54
    • 0033548566 scopus 로고    scopus 로고
    • Clusterin has chaperone-like activity similar to that of small heat shock proteins
    • HUMPHREYS DT CARVER JA, EASTERBROOK-SMITH SB, WILSON MR: Clusterin has chaperone-like activity similar to that of small heat shock proteins. J. Biol. Chem. (1999) 274:6875-6881.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6875-6881
    • Humphreys, D.T.1    Carver, J.A.2    Easterbrook-Smith, S.B.3    Wilson, M.R.4
  • 55
    • 11244308115 scopus 로고    scopus 로고
    • Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer
    • TAKAHASHI M, LIN YM, NAKAMURA Y, FURUKAWA Y: Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer. Oncogene (2004) 9:9289-9294.
    • (2004) Oncogene , vol.9 , pp. 9289-9294
    • Takahashi, M.1    Lin, Y.M.2    Nakamura, Y.3    Furukawa, Y.4
  • 56
    • 0030664673 scopus 로고    scopus 로고
    • Stress-induced transcription of the clusterinl apo J gene
    • MICHEL D, CHATELAIN G, NORTH S, BRUN G: Stress-induced transcription of the clusterinl apo J gene. Biochem. J. (1997) 328:45-50.
    • (1997) Biochem. J. , vol.328 , pp. 45-50
    • Michel, D.1    Chatelain, G.2    North, S.3    Brun, G.4
  • 57
    • 15944390264 scopus 로고    scopus 로고
    • Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer
    • GLEAVE M, MIYAKE H: Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer. World J. Urol. (2005) 23:38-46.
    • (2005) World J. Urol. , vol.23 , pp. 38-46
    • Gleave, M.1    Miyake, H.2
  • 58
    • 28444443360 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotide therapy targeting clusterin gene for prostate cancer: Vancouver experience from discovery to clinic
    • MIYAKE H, HARA I, GLEAVE ME: Antisense oligodeoxynucleotide therapy targeting clusterin gene for prostate cancer: Vancouver experience from discovery to clinic. Int. J. Urol. (2005) 12:785-794.
    • (2005) Int. J. Urol. , vol.12 , pp. 785-794
    • Miyake, H.1    Hara, I.2    Gleave, M.E.3
  • 59
    • 5644249330 scopus 로고    scopus 로고
    • Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent
    • CHEN T, TURNER J, McCARTHY S, SCALTRITI M, BETTUZZI S, YEATMAN TJ: Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent. Cancer Res. (2004) 64:7412-7419.
    • (2004) Cancer Res. , vol.64 , pp. 7412-7419
    • Chen, T.1    Turner, J.2    Mccarthy, S.3    Scaltriti, M.4    Bettuzzi, S.5    Yeatman, T.J.6
  • 60
    • 10844290787 scopus 로고    scopus 로고
    • Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis
    • SCALTRITI M, BETTUZZI S, SHARRARD RM, CAPORALI A, CACCAMO AE, MAITLAND NJ: Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis. Br. J. Cancer (2004) 91:1842-18 50.
    • (2004) Br. J. Cancer , vol.91 , pp. 1842-1850
    • Scaltriti, M.1    Bettuzzi, S.2    Sharrard, R.M.3    Caporali, A.4    Caccamo, A.E.5    Maitland, N.J.6
  • 61
    • 4344616635 scopus 로고    scopus 로고
    • Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells
    • SCALTRITI M, SANTAMARIA A, PACIUCCI R, BETTUZZI S: Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells. Cancer Res. (2004) 64:6174-6182.
    • (2004) Cancer Res. , vol.64 , pp. 6174-6182
    • Scaltriti, M.1    Santamaria, A.2    Paciucci, R.3    Bettuzzi, S.4
  • 62
    • 0037837729 scopus 로고    scopus 로고
    • Synthesis and functional analyses of nuclear clusterin, a cell death protein
    • LESKOV KS, KLOKOV DY, LI J, KINSELLA TJ, BOOTHMAN DA: Synthesis and functional analyses of nuclear clusterin, a cell death protein. J. Biol. Chem. (2003) 278:11590-11600.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11590-11600
    • Leskov, K.S.1    Klokov, D.Y.2    Li, J.3    Kinsella, T.J.4    Boothman, D.A.5
  • 63
    • 1842589298 scopus 로고    scopus 로고
    • Modulation of different clusterin isoforms in human colon tumorigenesis
    • PUCCI S, BONANNO E, PICHIORRI F, ANGELONI C, SPAGNOLI LG: Modulation of different clusterin isoforms in human colon tumorigenesis. Oncogene (2004) 23:2298-2304.
    • (2004) Oncogene , vol.23 , pp. 2298-2304
    • Pucci, S.1    Bonanno, E.2    Pichiorri, F.3    Angeloni, C.4    Spagnoli, L.G.5
  • 64
    • 0034705103 scopus 로고    scopus 로고
    • Nuclear clusterin/XIP8, an X-ray-induced Ku70-binding protein that signals cell death
    • YANG CR, LESKOV K, HOSLEY-EBERLEIN K et al.: Nuclear clusterin/XIP8, an X-ray-induced Ku70-binding protein that signals cell death. Proc. Natl. Acad. Sci. USA (2000) 97:5907-5912.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5907-5912
    • Yang, C.R.1    Leskov, K.2    Hosley-eberlein, K.3
  • 65
    • 0042665410 scopus 로고    scopus 로고
    • Alternations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis
    • O'SULLIVAN J, WHYTE L, DRAKE J, TENNISWOOD M: Alternations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis. Cell Death Differ. (2003) 10:914-927.
    • (2003) Cell Death Differ. , vol.10 , pp. 914-927
    • O'Sullivan, J.1    Whyte, L.2    Drake, J.3    Tenniswood, M.4
  • 66
    • 0029871768 scopus 로고    scopus 로고
    • Transforming growth factor β (TGF-β)-induced nuclear localization of apolipoprotein J/clusterin in epithelial cells
    • REDDY KB, JIN G, KARODE MC, HARMONY JA, HOWE PH: Transforming growth factor β (TGF-β)-induced nuclear localization of apolipoprotein J/ clusterin in epithelial cells. Biochemistry (1996) 35:6157-6163.
    • (1996) Biochemistry , vol.35 , pp. 6157-6163
    • Reddy, K.B.1    Jin, G.2    Karode, M.C.3    Harmony, J.A.4    Howe, P.H.5
  • 67
    • 0036892878 scopus 로고    scopus 로고
    • Response to a lethal dose of heat shock by a transient up-regulation of clusterin expression followed by down-regulation and apoprosis in prostate and bladder cancer cells
    • WU AJ, PARK II, ZHAUNG L, LEE C: Response to a lethal dose of heat shock by a transient up-regulation of clusterin expression followed by down-regulation and apoprosis in prostate and bladder cancer cells. Prostate (2002) 53:277-285.
    • (2002) Prostate , vol.53 , pp. 277-285
    • Wu, A.J.1    Park, I.I.2    Zhaung, L.3    Lee, C.4
  • 68
    • 0029061350 scopus 로고
    • Prevention of cell death induced by tumor necrosis factor α in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin)
    • SENSIBAR JA, SUTKOWSKI DM, RAFFO A et al.: Prevention of cell death induced by tumor necrosis factor α in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin). Cancer Res. (1995) 55:2431-2437.
    • (1995) Cancer Res. , vol.55 , pp. 2431-2437
    • Sensibar, J.A.1    Sutkowski, D.M.2    Raffo, A.3
  • 69
    • 0037810710 scopus 로고    scopus 로고
    • Resistance to cytotoxic chemotherapy-induced apoptosis in human prostate cancer cells is associated with intracellular clusterin expression
    • MIYAKE H, HARA I, KAMIDONO S, GLEAVE ME, ETO H: Resistance to cytotoxic chemotherapy-induced apoptosis in human prostate cancer cells is associated with intracellular clusterin expression. Oncol. Rep. (2003) 10:469-473.
    • (2003) Oncol. Rep. , vol.10 , pp. 469-473
    • Miyake, H.1    Hara, I.2    Kamidono, S.3    Gleave, M.E.4    Eto, H.5
  • 70
    • 1642282641 scopus 로고    scopus 로고
    • Silencing expression of the clusterin/apolipoprotein J gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress
    • TROUGAKOS IP, SO A, JANSEN B, GLEAVE ME, GONOS ES: Silencing expression of the clusterin/apolipoprotein J gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress. Cancer Res. (2004) 64:1834-1842.
    • (2004) Cancer Res. , vol.64 , pp. 1834-1842
    • Trougakos, I.P.1    So, A.2    Jansen, B.3    Gleave, M.E.4    Gonos, E.S.5
  • 71
    • 4444222462 scopus 로고    scopus 로고
    • Nucleotide-based therapies targeting clusterin chemosensitizes human lung adenocarcinoma cells both in vitro and in vivo
    • JULY LV, BERALDI E, SO AI et al.: Nucleotide-based therapies targeting clusterin chemosensitizes human lung adenocarcinoma cells both in vitro and in vivo. Mol. Cancer Ther. (2004) 3:223-232.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 223-232
    • July, L.V.1    Beraldi, E.2    So, A.I.3
  • 74
    • 0036144277 scopus 로고    scopus 로고
    • Overexpression of clusterin in transitional cell carcinoma of the bladder is related to disease progression and recurrence
    • MIYAKE H, GLEAVE M, KAMIDONO S, HARA I: Overexpression of clusterin in transitional cell carcinoma of the bladder is related to disease progression and recurrence. Urology (2002) 59:150-154.
    • (2002) Urology , vol.59 , pp. 150-154
    • Miyake, H.1    Gleave, M.2    Kamidono, S.3    Hara, I.4
  • 75
    • 0036143452 scopus 로고    scopus 로고
    • Over expression of clusterin is an independent prognostic factor for non-papillary renal cell carcinoma
    • MIYAKE H, HARA S, ARAKAWA S, KAMIDONO S, HARA I: Over expression of clusterin is an independent prognostic factor for non-papillary renal cell carcinoma. J. Urol. (2002) 167:703-706.
    • (2002) J. Urol. , vol.167 , pp. 703-706
    • Miyake, H.1    Hara, S.2    Arakawa, S.3    Kamidono, S.4    Hara, I.5
  • 76
    • 25844444617 scopus 로고    scopus 로고
    • Expression of the secreted form of clusterin protein in renal cell carcinoma as a predictor of disease extension
    • KURAHASHI T, MURAMAKI M, YAMANAKA K, HARA I, MIYAKE H: Expression of the secreted form of clusterin protein in renal cell carcinoma as a predictor of disease extension. BJU Int. (2005) 96:895-899.
    • (2005) BJU Int. , vol.96 , pp. 895-899
    • Kurahashi, T.1    Muramaki, M.2    Yamanaka, K.3    Hara, I.4    Miyake, H.5
  • 77
    • 0035675829 scopus 로고    scopus 로고
    • Synergistic chemosensitization and inhibition of tumor growth and metastasis by the antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model
    • MIYAKE H, HARA I. KAMIDONO S, GLEAVE ME: Synergistic chemosensitization and inhibition of tumor growth and metastasis by the antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model. Clin. Cancer Res. (2001) 7:4245-4252.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 4245-4252
    • Miyake, H.1    Hara, I.2    Kamidono, S.3    Gleave, M.E.4
  • 78
    • 2442565896 scopus 로고    scopus 로고
    • Synergistic antitumor activity by combined treatment with gemcitabine and antisense oligodeoxynucleotide targeting clusterin gene in an intravesical administration model against human bladder cancer KoTCC- I cells
    • MIYAKE H, ETO H, HARA I, SO A, LI D, GLEAVE ME: Synergistic antitumor activity by combined treatment with gemcitabine and antisense oligodeoxynucleotide targeting clusterin gene in an intravesical administration model against human bladder cancer KoTCC- I cells. J. Urol. (2004) 171:2477-2481.
    • (2004) J. Urol. , vol.171 , pp. 2477-2481
    • Miyake, H.1    Eto, H.2    Hara, I.3    So, A.4    Li, D.5    Gleave, M.E.6
  • 79
    • 14644404957 scopus 로고    scopus 로고
    • Therapeutic efficacy of adenoviral-mediated p53 gene transfer is synergistically enhanced by combined use of antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model
    • MIYAKE H, YAMANAKA K, MURAMAKI M, HARA I, GLEAVE ME: Therapeutic efficacy of adenoviral-mediated p53 gene transfer is synergistically enhanced by combined use of antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model. Neoplasia (2005) 7:171-179.
    • (2005) Neoplasia , vol.7 , pp. 171-179
    • Miyake, H.1    Yamanaka, K.2    Muramaki, M.3    Hara, I.4    Gleave, M.E.5
  • 80
    • 0034870685 scopus 로고    scopus 로고
    • Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the anti-apoptotic gene clusterin
    • ZELLWEGER T, MIYAKE H, JULY LV, AKBARI M, KIYAMA S, GLEAVE ME: Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the anti-apoptotic gene clusterin. Neoplasia (2001) 3:360-367.
    • (2001) Neoplasia , vol.3 , pp. 360-367
    • Zellweger, T.1    Miyake, H.2    July, L.V.3    Akbari, M.4    Kiyama, S.5    Gleave, M.E.6
  • 81
    • 0023447259 scopus 로고
    • Selective elimination of mRNAs in vivo: Complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity
    • DASH P, LOTAN I, KNAPP M, KANDEL ER, GOELET P: Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity. Proc. Natl. Acad. Sci. USA (1987) 84:7896-7900.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7896-7900
    • Dash, P.1    Lotan, I.2    Knapp, M.3    Kandel, E.R.4    Goelet, P.5
  • 82
    • 0027284424 scopus 로고
    • Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides
    • DOMINSKI Z, KOLE R: Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides. Proc. Natl. Acad. Sci. USA (1993) 90:8673-8677.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8673-8677
    • Dominski, Z.1    Kole, R.2
  • 83
    • 0025312339 scopus 로고
    • Tumor-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide
    • McMANAWAY ME, NECKERS LM, LOKE SL et al.: Tumor-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide. Lancet (1990) 335:808-811.
    • (1990) Lancet , vol.335 , pp. 808-811
    • McManaway, M.E.1    Neckers, L.M.2    Loke, S.L.3
  • 84
    • 0024517255 scopus 로고
    • Inhibition ofexpression of SV40 virus large T-antigen by antisense oligodeoxyribonucleotides
    • WESTERMANN P, GROSS B, HOINKIS G: Inhibition ofexpression of SV40 virus large T-antigen by antisense oligodeoxyribonucleotides. Biomed. Biochim. Acta (1989) 48:85-93.
    • (1989) Biomed. Biochim. Acta , vol.48 , pp. 85-93
    • Westermann, P.1    Gross, B.2    Hoinkis, G.3
  • 85
    • 0026648540 scopus 로고
    • Modulation of eukaryotic initiation factof-4E binding to 5′-capped oligoribonucleotides by modified antisense oligonucleotides
    • BAKER BF, MIRAGLIA L, HAGEDORN CH: Modulation of eukaryotic initiation factof-4E binding to 5′-capped oligoribonucleotides by modified antisense oligonucleotides. J. Biol. Chem. (1992) 267:11495-11499.
    • (1992) J. Biol. Chem. , vol.267 , pp. 11495-11499
    • Baker, B.F.1    Miraglia, L.2    Hagedorn, C.H.3
  • 86
  • 87
    • 0011836520 scopus 로고    scopus 로고
    • Structural modifications toward improved antisense oligonucleotides
    • MATTEUCCI M: Structural modifications toward improved antisense oligonucleotides. Perspectives Drug Dis. Des. (1996) 4:1-16.
    • (1996) Perspectives Drug Dis. Des. , vol.4 , pp. 1-16
    • Matteucci, M.1
  • 88
    • 0022428810 scopus 로고
    • Reversed-phase high-performance liquid chromatographic separation of diastereomeric phosphorothioate analogues of oligodeoxyribonucleotides and other backbone-modified congeners of DNA
    • STEC WJ, ZON G, UZANSKI B: Reversed-phase high-performance liquid chromatographic separation of diastereomeric phosphorothioate analogues of oligodeoxyribonucleotides and other backbone-modified congeners of DNA. J. Chromatogr. (1985) 326:263-280.
    • (1985) J. Chromatogr. , vol.326 , pp. 263-280
    • Stec, W.J.1    Zon, G.2    Uzanski, B.3
  • 89
    • 0029977448 scopus 로고    scopus 로고
    • Antitumor activity of a phosphorothioate antisense oligodeoxynucletide targeted against C-raf kinase
    • MONIA BP, JOHNSTON JE GEIGER T, MULLER M, FABBRO D: Antitumor activity of a phosphorothioate antisense oligodeoxynucletide targeted against C-raf kinase. Nat. Med. (1996) 2:668-675.
    • (1996) Nat. Med. , vol.2 , pp. 668-675
    • Monia, B.P.1    Johnston, J.E.2    Geiger, T.3    Muller, M.4    Fabbro, D.5
  • 90
    • 25144436540 scopus 로고    scopus 로고
    • Enhanced radiosensitivity by inhibition of the antiapoptotic gene clusterin using antisense oligodeoxynucleotide in a human bladder cancer model
    • YAMANAKA K, GLEAVE M, MURAMAKI M, HARA I, MIYAKE H: Enhanced radiosensitivity by inhibition of the antiapoptotic gene clusterin using antisense oligodeoxynucleotide in a human bladder cancer model. Oncol. Rep. (2005) 13:885-890.
    • (2005) Oncol. Rep. , vol.13 , pp. 885-890
    • Yamanaka, K.1    Gleave, M.2    Muramaki, M.3    Hara, I.4    Miyake, H.5
  • 91
    • 0034606686 scopus 로고    scopus 로고
    • Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides
    • MIYAKE H, TOLCHER A, GLEAVE ME: Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides. J. Natl. Cancer Inst. (2000) 92:34-41.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 34-41
    • Miyake, H.1    Tolcher, A.2    Gleave, M.E.3
  • 92
    • 0035869667 scopus 로고    scopus 로고
    • Synergistic chemosensitization and inhibition of progression to androgen independence by antisense Bcl-2 oligodeoxynucleotide and paclitaxel in the LNCaP prostate tumor model
    • LEUNG S, MIYAKE H, ZELLWEGER T, TOLCHER A, GLEAVE ME: Synergistic chemosensitization and inhibition of progression to androgen independence by antisense Bcl-2 oligodeoxynucleotide and paclitaxel in the LNCaP prostate tumor model. Int. J. Cancer (2001) 91:846-850.
    • (2001) Int. J. Cancer , vol.91 , pp. 846-850
    • Leung, S.1    Miyake, H.2    Zellweger, T.3    Tolcher, A.4    Gleave, M.E.5
  • 93
    • 0034013539 scopus 로고    scopus 로고
    • Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin but not by glycosylation inhibitor, tunicamycin in human prostate cancer cells
    • MIYAKE H, HARA I, ARAKAWA S, KAMIDONO S: Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin but not by glycosylation inhibitor, tunicamycin in human prostate cancer cells. J. Cell. Biochem. (2000) 77:396-408.
    • (2000) J. Cell. Biochem. , vol.77 , pp. 396-408
    • Miyake, H.1    Hara, I.2    Arakawa, S.3    Kamidono, S.4
  • 94
    • 0032741282 scopus 로고    scopus 로고
    • Progression to androgen-independence is delayed by adjuvant treatment with antisense Bcl-2 oligodeoxynucleotides after castration in the LNCaP prostate tumor model
    • GLEAVE M, TOLCHER A, MIYAKE H et al: Progression to androgen-independence is delayed by adjuvant treatment with antisense Bcl-2 oligodeoxynucleotides after castration in the LNCaP prostate tumor model. Clin. Cancer Res. (1999) 5:2891-2898.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2891-2898
    • Gleave, M.1    Tolcher, A.2    Miyake, H.3
  • 95
    • 0028019410 scopus 로고
    • Gene inhibition using antisense oligodeoxynucleotides
    • WAGNER RW. Gene inhibition using antisense oligodeoxynucleotides. Nature (1994) 372:333-335.
    • (1994) Nature , vol.372 , pp. 333-335
    • Wagner, R.W.1
  • 96
    • 0027168725 scopus 로고
    • Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
    • MONIA BP, LESNIK EA, GONZALEZ C et al.: Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem. (1993) 268:14514-14522.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14514-14522
    • Monia, B.P.1    Lesnik, E.A.2    Gonzalez, C.3
  • 97
    • 0029867162 scopus 로고    scopus 로고
    • Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-α by the incorporation of 2′-O-propyl modifications
    • McKAY RA, CUMMINS LL, GRAHAM MJ et al: Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-α by the incorporation of 2′-O-propyl modifications. Nucleic Acids Res. (1996) 24:411-417.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 411-417
    • McKay, R.A.1    Cummins, L.L.2    Graham, M.J.3
  • 98
    • 0034883854 scopus 로고    scopus 로고
    • Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2′-O-(2-methoxy)ethyl chemistry
    • ZELLWEGER T, MIYAKE H, COOPER S et al.: Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2′-O-(2-methoxy)ethyl chemistry. J. Pharmacol. Exp. Ther. (2001) 298:934-940.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 934-940
    • Zellweger, T.1    Miyake, H.2    Cooper, S.3
  • 99
  • 100
    • 21744452813 scopus 로고    scopus 로고
    • Efficacy of an intratumoral controlled release formulation of clusterin antisense oligonucleotide complexed with chitosan containing paclitaxel in prostate cancer xenograft models
    • SPRINGATE CM, JACKSON JK, GLEAVE ME, BURT HM: Efficacy of an intratumoral controlled release formulation of clusterin antisense oligonucleotide complexed with chitosan containing paclitaxel in prostate cancer xenograft models. Cancer Chemother. Pharmacol. (2005) 56:239-247.
    • (2005) Cancer Chemother. Pharmacol. , vol.56 , pp. 239-247
    • Springate, C.M.1    Jackson, J.K.2    Gleave, M.E.3    Burt, H.M.4
  • 101
    • 28744438393 scopus 로고    scopus 로고
    • The inhibition of angiogenesis by antisense oligonucleotides to clusterin
    • JACKSON JK, GLEAVE ME, GLEAVE J, BURT HM: The inhibition of angiogenesis by antisense oligonucleotides to clusterin. Angiogenesis (2005) 8:229-238.
    • (2005) Angiogenesis , vol.8 , pp. 229-238
    • Jackson, J.K.1    Gleave, M.E.2    Gleave, J.3    Burt, H.M.4
  • 102
    • 24744470522 scopus 로고    scopus 로고
    • A Phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2′-methoxyethl antisense oligonucleotide of clusterin, in patients with localized prostate cancer
    • CHI KN, EISENHAUER E, FAZLI L et al.: A Phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2′-methoxyethl antisense oligonucleotide of clusterin, in patients with localized prostate cancer. J. Natl. Cancer Inst. (2005) 97:1287-1296.
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 1287-1296
    • Chi, K.N.1    Eisenhauer, E.2    Fazli, L.3
  • 103
    • 30344436175 scopus 로고    scopus 로고
    • A Phase I study of a second generation antisense oligonucleotide to clusterin (OGX-011) in combination with docetaxel: NCIC CTG IND. 154
    • CHI KN, EISENHAUER E, SIU L et al: A Phase I study of a second generation antisense oligonucleotide to clusterin (OGX-011) in combination with docetaxel: NCIC CTG IND. 154. J. Clin. Oncol. (2005) 23:213S.
    • (2005) J. Clin. Oncol. , vol.23
    • Chi, K.N.1    Eisenhauer, E.2    Siu, L.3
  • 104
    • 23844543479 scopus 로고    scopus 로고
    • Antisense oligonucleotides: The state of the art
    • ABOUL-FADL T. Antisense oligonucleotides: the state of the art. Curr. Med. Chem. (2005) 12:2193-2214.
    • (2005) Curr. Med. Chem. , vol.12 , pp. 2193-2214
    • Aboul-Fadl, T.1
  • 105
    • 26844431930 scopus 로고    scopus 로고
    • Peptide nucleic acids (PNAs), a chemical overview
    • PORCHEDDU A, GIACOMELLI G: Peptide nucleic acids (PNAs), a chemical overview. Curr. Med. Chem. (2005) 12:2561-2599.
    • (2005) Curr. Med. Chem. , vol.12 , pp. 2561-2599
    • Porcheddu, A.1    Giacomelli, G.2
  • 106
    • 0034096268 scopus 로고    scopus 로고
    • A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells
    • ZANGEMEISTER-WITTKE U, LEECH SH, OLIE RA et al: A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells. Clin. Cancer Res. (2000) 6:2547-2555.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2547-2555
    • Zangemeister-Wittke, U.1    Leech, S.H.2    Olie, R.A.3
  • 107
    • 0035925537 scopus 로고    scopus 로고
    • Activity of a novel bcl-2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins
    • GAUTSCHI O, TSCHOPP S, OLIE RA et al: Activity of a novel bcl-2/ bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins. J. Natl. Cancer Inst. (2001) 93:463-471.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 463-471
    • Gautschi, O.1    Tschopp, S.2    Olie, R.A.3
  • 108
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • JONES JI, CLEMMONS DR: Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. (1995) 16:3-34.
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 109
    • 0030810926 scopus 로고    scopus 로고
    • X-linked IAP is a direct inhibitor of cell-death proteases
    • DEVERAUX QL, TAKAHASHI R, SALVESEN GS, REED JC: X-linked IAP is a direct inhibitor of cell-death proteases. Nature (1997) 388:300-304.
    • (1997) Nature , vol.388 , pp. 300-304
    • Deveraux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 110
    • 0030772022 scopus 로고    scopus 로고
    • Target to apoptosis: A hopeful weapon for prostate cancer
    • TANG DG, PORTER AT. Target to apoptosis: a hopeful weapon for prostate cancer. Prostate (1997) 32:284-293.
    • (1997) Prostate , vol.32 , pp. 284-293
    • Tang, D.G.1    Porter, A.T.2
  • 111
    • 0032730633 scopus 로고    scopus 로고
    • Phase I study of an antisense oligonucleotide to protein-kinase C-α (ISIS3521/CGP64128A) in patients with cancer
    • YUEN AR, HALSEY J, FISHER GA et al.: Phase I study of an antisense oligonucleotide to protein-kinase C-α (ISIS3521/CGP64128A) in patients with cancer. Clin. Cancer Res. (1999) 5:3357-3363.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3357-3363
    • Yuen, A.R.1    Halsey, J.2    Fisher, G.A.3
  • 112
    • 0034720202 scopus 로고    scopus 로고
    • Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component
    • KONDO Y, KOGA S, KOMATA T, KONDO S: Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component. Oncogene (2000) 19:2205-2211.
    • (2000) Oncogene , vol.19 , pp. 2205-2211
    • Kondo, Y.1    Koga, S.2    Komata, T.3    Kondo, S.4


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