Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells

Journal of Cellular Biochemistry

Volumn 77, Issue 3, 2000, Pages 396-408

  Miyake, Hideaki ^a,b   Hara, Isao ^a   Arakawa, Soichi ^a   Kamidono, Sadao ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

Apoptosis; Calcium ionophore; Glycosylation inhibitor; GRP78; Prostate cancer

Indexed keywords

CALCIUM IONOPHORE; GLUCOSE REGULATED PROTEIN; GLUCOSE REGULATED PROTEIN 78; IONOMYCIN; TUNICAMYCIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN INDUCTION; STRESS;

ANDROGENS; ANTI-BACTERIAL AGENTS; APOPTOSIS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CALCIUM; CARRIER PROTEINS; DNA FRAGMENTATION; GLYCOSYLATION; HEAT-SHOCK PROTEINS; HUMANS; IONOMYCIN; IONOPHORES; MALE; MOLECULAR CHAPERONES; OLIGONUCLEOTIDES, ANTISENSE; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; TUNICAMYCIN; UP-REGULATION;

EID: 0034013539     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(20000601)77:3<396::AID-JCB5>3.0.CO;2-5     Document Type: Article

References (24)

1. Chatterjee S, Hirota H, Belfi CA, Berger SJ, Berger NA. 1997. Hypersensitivity to DNA cross-linking agents associated with up-regulation of glucose-regulated stress protein GRP78. Cancer Res 57:5112-5116.
2. Crooke ST. 1992. Therapeutic applications of oligonucleotides. Annu Rev Pharmacol Toxicol 32:329-376.
3. Fleshner N, Fair WR, Huryk R, Heston WD. 1999. Vitamin E inhibits the high-fat diet promoted growth of established human prostate LNCaP tumors in nude mice. J Urol 161:1651-1654.
4. Hughes CS, Shen JW, Subjeck JR. 1989. Resistance to etoposide induced by three glucose-regulated stresses in Chinese hamster ovary cells. Cancer Res 49:4452-4454.
5. Isaacs JT. 1987. Development and characteristics of the available animal model system for the study of prostatic cancer. Prog Clin Biol Res 239:513-576.
6. Jamora C, Dennert G, Lee AS. 1996. Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci USA 93:7690-7694.
7. Koong AC, Chen EY, Lee AS, Brown JM, Giaccia AJ. 1994. Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction. Int J Radiat Oncol Biol Phys 28:661-666.
8. Lee AS. 1987. Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells. Trends Biochem Sci 12:20-23.
9. Lee AS. 1992. Mammalian stress response: induction of the glucose-regulated protein family. Curr Opin Cell Biol 4:267-273.
10. Li LJ, Li X, Ferrario A, Rucker N, Liu ES, Wong S, Gomer CJ, Lee AS. 1992. Establishment of a Chinese hamster ovary cell line which express grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94. J Cell Physiol 153:575-582.
11. 2+ -ATPase inhibitor thapsigargin. J Biol Chem 268: 12003-12009.
12. Little E, Lee AS. 1995. Generation of a mammalian cell line deficient in glucose-regulated protein stress induction through targeted ribozyme driven by a stress-inducible promoter. J Biol Chem 270:9526-9534.
13. Lytton J, Westlin M, Hanley MR. 1991. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J Biol Chem 266: 17067-17071.
14. McCormick TS, McColl KS, Distelhorst CW. 1997. Mouse lymphoma cells destined to undergo apoptosis in response to thapsigargin treatment fail to generate a calcium-mediated grp78/grp94 stress response. J Biol Chem 272:6087-6092.
15. Miyake H, Hanada N, Nakamura H, Kagawa S, Fujiwara T, Hara I, Eto H, Gohji K, Arakawa S, Kamidono S, Saya H. 1998. Overexpression of Bcl-2 in bladder cancer cells inhibits apoptosis induced by cisplatin and adenoviral-mediated p53 gene transfer. Oncogene 16: 933-943.
16. Miyake H, Tolcher A, Gleave ME. 1999. Antisense Bcl-2 oligodeoxynucleotides inhibit progression to androgen-independence after castration in the Shionogi tumor model. Cancer Res 59:4030-4034.
17. Morimoto RI. 1993. Cells in stress: transcriptional activation of heat shock genes. Science 259:1409-1410.
18. Munro S, Pelham HR. 1986. An HSP70-like protein in the ER: identity with the 78-kd glucose-regulated protein and immunoglobulin heavy chain binding protein. Cell 46:291-300.
19. Saijo Y, Perlaky L, Wang H, Busch H. 1994. Pharmacokinetics, tissue distribution, and stability of antisense oligodeoxynucleotide phosphorothioate ISIS 3466 in mice. Oncol Res 6:243-24922.
20. Sensibar JA, Sutkowski DM, Raffo A, Buttyan R, Griswold MD, Sylvester SR, Kozlowski JM, Lee C. 1995. Prevention of cell death induced by tumor necrosis factor α in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin). Cancer Res 55:2431-2437.
21. Shen J, Hughes C, Chao C, Cai J, Bartels C, Gessner T, Subjeck J. 1987. Coinduction of glucose-regulated proteins and doxorubicin resistance in Chinese hamster cells. Proc Natl Acad Sci USA 84:3278-3282.
22. Sugawara S, Takeda K, Lee A, Dennert G. 1993. Suppression of stress protein GRP78 induction in tumor B/C10ME eliminates resistance to cell mediated cytotoxicity. Cancer Res 53:6001-6005.
23. 2+ -ATPase. Proc Natl Acad Sci USA 87:2466-2470.
24. Wooden SK, Li LJ, Navarro D, Qadri I, Pereira L, Lee AS. 1991. Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I. Mol Cell Biol 11:5612-5623.