-
1
-
-
0027369623
-
Overview of phase III trials on combined androgen treatment in patients with metastatic prostate cancer
-
Phila.
-
Denis, L., and Murphy, G. P. Overview of Phase III trials on combined androgen treatment in patients with metastatic prostate cancer. Cancer (Phila. ), 72: 3888-3895, 1993.
-
(1993)
Cancer
, vol.72
, pp. 3888-3895
-
-
Denis, L.1
Murphy, G.P.2
-
2
-
-
0032323546
-
Management of hormone refractory prostate cancer: Current standards and future prospects
-
Oh, W. K., and Kantoff, P. W. Management of hormone refractory prostate cancer: current standards and future prospects. J. Urol., 160: 1220-1229, 1998.
-
(1998)
J. Urol.
, vol.160
, pp. 1220-1229
-
-
Oh, W.K.1
Kantoff, P.W.2
-
3
-
-
0022546957
-
Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma
-
Tsujimoto Y., and Croce, C. M. Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc. Natl. Acad. Sci. USA, 83: 5214-5218, 1986.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 5214-5218
-
-
Tsujimoto, Y.1
Croce, C.M.2
-
4
-
-
0029077281
-
Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo
-
Raffo, A. J., Periman, H., Chen, M. W., Streitman, J. S., and Buttyan, R. Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo. Cancer Res., 55: 4438-4445, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4438-4445
-
-
Raffo, A.J.1
Periman, H.2
Chen, M.W.3
Streitman, J.S.4
Buttyan, R.5
-
5
-
-
0029776580
-
Apoptosis resistance increases with metastatic potential in cells of the human LNCaP prostate carcinoma line
-
McConkey, D. J., Greene, G., and Pettaway, C. A. Apoptosis resistance increases with metastatic potential in cells of the human LNCaP prostate carcinoma line. Cancer Res., 56: 5594-5599, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 5594-5599
-
-
McConkey, D.J.1
Greene, G.2
Pettaway, C.A.3
-
6
-
-
0029795396
-
Elevated levels of apoptosis regulatory proteins p53 and bcl-2 are independent prognostic biomarkers in surgically treated clinically localized prostate cancer
-
Bauer, J. J., Sesterhenn, I. A., Mostofi, F. K., McLeod, D. G., Srivastava, S., and Moul, J. W. Elevated levels of apoptosis regulatory proteins p53 and bcl-2 are independent prognostic biomarkers in surgically treated clinically localized prostate cancer. J. Urol., 156: 1511-1516, 1996.
-
(1996)
J. Urol.
, vol.156
, pp. 1511-1516
-
-
Bauer, J.J.1
Sesterhenn, I.A.2
Mostofi, F.K.3
McLeod, D.G.4
Srivastava, S.5
Moul, J.W.6
-
7
-
-
0032458445
-
j-67 labeling index, p53 and Bcl-2 immunoreactivity
-
j-67 labeling index, p53 and Bcl-2 immunoreactivity. J. Urol., 159: 1437-1443, 1998.
-
(1998)
J. Urol.
, vol.159
, pp. 1437-1443
-
-
Grossfeld, G.D.1
Olumi, A.F.2
Connolly, J.A.3
Chew, K.4
Gibney, J.5
Bhargava, V.6
Waldman, F.M.7
Carroll, P.R.8
-
8
-
-
0027093255
-
Expression of the protooncogene Bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
-
McDonnell, T. J., Troncoso, P., Brisby, S. M., Logothesis, C. L., Chung, L. W. K., Hsieh, J. T., Tu, S. M., and Campbell, M. L. Expression of the protooncogene Bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res., 52: 6940-6944, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 6940-6944
-
-
McDonnell, T.J.1
Troncoso, P.2
Brisby, S.M.3
Logothesis, C.L.4
Chung, L.W.K.5
Hsieh, J.T.6
Tu, S.M.7
Campbell, M.L.8
-
9
-
-
0027773015
-
Detection of the apoptosis-suppressing oncoprotein Bcl-2 in hormone-refractory human prostate cancers
-
Colombel, M., Symmans, F., Gil, S., O'Toole, K. M., Choplin, D., Benson, M., Olsson, C. A., Korsmeyer, S., and Buttyan, R. Detection of the apoptosis-suppressing oncoprotein Bcl-2 in hormone-refractory human prostate cancers. Am. J. Pathol., 143: 390-400, 1993.
-
(1993)
Am. J. Pathol.
, vol.143
, pp. 390-400
-
-
Colombel, M.1
Symmans, F.2
Gil, S.3
O'Toole, K.M.4
Choplin, D.5
Benson, M.6
Olsson, C.A.7
Korsmeyer, S.8
Buttyan, R.9
-
10
-
-
0025246690
-
Effects of androgen withdrawal on the stem cell composition of the Shionogi carcinoma
-
Bruchovsky, N., Rennie, P. S., Coldman, A. J., Goldenberg, S. L., To, M., and Lawson, D. Effects of androgen withdrawal on the stem cell composition of the Shionogi carcinoma. Cancer Res., 50: 2275-2282, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 2275-2282
-
-
Bruchovsky, N.1
Rennie, P.S.2
Coldman, A.J.3
Goldenberg, S.L.4
To, M.5
Lawson, D.6
-
11
-
-
0026721173
-
Therapeutic applications of oligonucleotides
-
Crooke, S. T. Therapeutic applications of oligonucleotides. Annu. Rev. Pharmacol. Toxicol., 32: 329-376, 1993.
-
(1993)
Annu. Rev. Pharmacol. Toxicol.
, vol.32
, pp. 329-376
-
-
Crooke, S.T.1
-
12
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
-
Monia, B. P., Johnston, J. F., Geiger, T., Muller, M., and Fabbro, D. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat. Med., 2: 668-675, 1996.
-
(1996)
Nat. Med.
, vol.2
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
Muller, M.4
Fabbro, D.5
-
13
-
-
0029740475
-
In vitro and in vivo reversal of multidrug resistance in a human leukemia-resistant cell line by mdr1 antisense oligodeoxynucleotides
-
Cucco, C., and Calabretta, B. In vitro and in vivo reversal of multidrug resistance in a human leukemia-resistant cell line by mdr1 antisense oligodeoxynucleotides. Cancer Res., 56: 4332-4337, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4332-4337
-
-
Cucco, C.1
Calabretta, B.2
-
14
-
-
0030807543
-
Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence
-
Ziegler, A., Luedke, G. H., Fabbro, D., Altman, K. H., Stahel, R. A., and Zangemeister-Wittke, U. Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence. J. Natl. Cancer Inst., 89: 1027-1036, 1997.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 1027-1036
-
-
Ziegler, A.1
Luedke, G.H.2
Fabbro, D.3
Altman, K.H.4
Stahel, R.A.5
Zangemeister-Wittke, U.6
-
15
-
-
0031907428
-
Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
-
Jansen, B., Schlagbauer-Wadl, H., Brown, B. D., Bryan, R. N., van Elisa, A., Muller, M., Wolff, K., Eichler, H. G., and Pehamberger, H. bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat. Med., 4: 232-234, 1998.
-
(1998)
Nat. Med.
, vol.4
, pp. 232-234
-
-
Jansen, B.1
Schlagbauer-Wadl, H.2
Brown, B.D.3
Bryan, R.N.4
Van Elisa, A.5
Muller, M.6
Wolff, K.7
Eichler, H.G.8
Pehamberger, H.9
-
16
-
-
0023797337
-
Gene expression during the early phase of regression of the androgen-dependent Shionogi mouse mammary carcinoma
-
Rennie, P. S., Bruchovsky, N., Buttyan, R., and Cheng, H. Gene expression during the early phase of regression of the androgen-dependent Shionogi mouse mammary carcinoma. Cancer Res., 48: 6309-6312, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 6309-6312
-
-
Rennie, P.S.1
Bruchovsky, N.2
Buttyan, R.3
Cheng, H.4
-
17
-
-
0018136726
-
Classification of dependent and autonomous variants of Shionogi mammary carcinoma based on heterogeneous patterns of androgen binding
-
Bruchovsky, N., and Rennie, P. S. Classification of dependent and autonomous variants of Shionogi mammary carcinoma based on heterogeneous patterns of androgen binding. Cell, 13: 272-280, 1978.
-
(1978)
Cell
, vol.13
, pp. 272-280
-
-
Bruchovsky, N.1
Rennie, P.S.2
-
18
-
-
0026602518
-
Serum PSA levels in mice bearing human prostate LNCaP tumor are determined by tumor volume and endocrine and growth factors
-
Gleave, M. E., Hsieh, J. T., Wu, H-C., and Chung, L. W. K. Serum PSA levels in mice bearing human prostate LNCaP tumor are determined by tumor volume and endocrine and growth factors. Cancer Res., 52: 1598-1605, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1598-1605
-
-
Gleave, M.E.1
Hsieh, J.T.2
Wu, H.-C.3
Chung, L.W.K.4
-
19
-
-
0025875889
-
Acceleration of human prostate carcinoma growth in vivo by factors produced by prostate and bone fibroblasts
-
Gleave, M. E., Hsieh, J. T., Gao, C., von Eschenbach, A. C., and Chung, L. W. K. Acceleration of human prostate carcinoma growth in vivo by factors produced by prostate and bone fibroblasts. Cancer Res., 51: 3753-3761, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 3753-3761
-
-
Gleave, M.E.1
Hsieh, J.T.2
Gao, C.3
Von Eschenbach, A.C.4
Chung, L.W.K.5
-
20
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature (Lond. ), 371: 346-347, 1994.
-
(1994)
Nature (Lond. )
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
21
-
-
0023662325
-
Molecular analysis of mbcl-2: Structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma
-
Negrini, M., Silini, E., Kozak, C., Tsujimoto, Y., and Croce, C. M. Molecular analysis of mbcl-2: structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma. Cell, 49: 455-463, 1987.
-
(1987)
Cell
, vol.49
, pp. 455-463
-
-
Negrini, M.1
Silini, E.2
Kozak, C.3
Tsujimoto, Y.4
Croce, C.M.5
-
22
-
-
0028117635
-
Pharmacokinetics, tissue distribution, and stability of antisense oligodeoxynucleotide phosphorothioate ISIS 3466 in mice
-
Saijo, Y., Perlaky, L., Wang, H., and Busch, H. Pharmacokinetics, tissue distribution, and stability of antisense oligodeoxynucleotide phosphorothioate ISIS 3466 in mice. Oncol. Res., 6: 243-249, 1994.
-
(1994)
Oncol. Res.
, vol.6
, pp. 243-249
-
-
Saijo, Y.1
Perlaky, L.2
Wang, H.3
Busch, H.4
-
23
-
-
0030822629
-
Development of a hammerhead riboenzyme against bcl-2. I. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer
-
Dorai, T., Olsson, C. A., Katz, A. E., and Buttyan, R. Development of a hammerhead riboenzyme against bcl-2. I. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer. Prostate, 32: 246-258, 1997.
-
(1997)
Prostate
, vol.32
, pp. 246-258
-
-
Dorai, T.1
Olsson, C.A.2
Katz, A.E.3
Buttyan, R.4
-
24
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
-
Washington DC
-
Stein, C. A., and Cheng, Y. C. Antisense oligonucleotides as therapeutic agents - is the bullet really magical? Science (Washington DC), 261: 1004-1012, 1993.
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
Stein, C.A.1
Cheng, Y.C.2
-
25
-
-
0028806487
-
Does antisense exist?
-
Stein, C. A. Does antisense exist? Nat. Med., 1: 1119-1121, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 1119-1121
-
-
Stein, C.A.1
-
26
-
-
0030900680
-
Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal therapy of lymphoma
-
Wooldridge, J. E., Ballas, Z., Krieg, A. M., and Weiner, G. J. Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal therapy of lymphoma. Blood, 89: 2994-2998, 1997.
-
(1997)
Blood
, vol.89
, pp. 2994-2998
-
-
Wooldridge, J.E.1
Ballas, Z.2
Krieg, A.M.3
Weiner, G.J.4
-
27
-
-
0029619816
-
Kinetic characteristics of Escherichia coli RNase H1: Cleavage of various antisense oligonucleotide-RNA duplexes
-
Crooke, S. T., Lemonidis, K. M., Neilson, L., Griffey, R., Lesnik, E. A., and Monia, B. P. Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexes. Biochem. J., 312: 599-608, 1995.
-
(1995)
Biochem. J.
, vol.312
, pp. 599-608
-
-
Crooke, S.T.1
Lemonidis, K.M.2
Neilson, L.3
Griffey, R.4
Lesnik, E.A.5
Monia, B.P.6
-
28
-
-
0026573769
-
Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: Implications for antisense technology
-
Gao, W. Y., Han, F. S., Storm, C., Egan, W., and Cheng, Y. C. Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: implications for antisense technology. Mol. Pharmacol., 41: 223-229, 1992.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 223-229
-
-
Gao, W.Y.1
Han, F.S.2
Storm, C.3
Egan, W.4
Cheng, Y.C.5
-
29
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
-
Guvakova, M. A., Yakubov, L. A., Vlodavsky, I., Tonkison, J. L., and Stein, C. A. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J. Biol. Chem., 270: 2620-2627, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkison, J.L.4
Stein, C.A.5
-
30
-
-
0019254148
-
Human prostatic adenocarcinoma: Some characteristics of a serially transplantable line in nude mice (PC82)
-
Hoehn, W., Schroeder, F. H., Riemann, J. F., Joebsis, A. C., and Hermanek, P. Human prostatic adenocarcinoma: Some characteristics of a serially transplantable line in nude mice (PC82). Prostate, 1: 95-104, 1980.
-
(1980)
Prostate
, vol.1
, pp. 95-104
-
-
Hoehn, W.1
Schroeder, F.H.2
Riemann, J.F.3
Joebsis, A.C.4
Hermanek, P.5
-
31
-
-
0006338483
-
Bcl-2 promotes regeneration of served axons in mammalian CNS
-
Chen D. F., Sehneider, G. E., Martinou, J. C., and Tonegawa, S. Bcl-2 promotes regeneration of served axons in mammalian CNS. Nature (Lond. ), 385: 443-449, 1997.
-
(1997)
Nature (Lond. )
, vol.385
, pp. 443-449
-
-
Chen, D.F.1
Sehneider, G.E.2
Martinou, J.C.3
Tonegawa, S.4
-
32
-
-
0032555909
-
The action of Bax and bcl-2 on T cell selection
-
Williams, O., Norton, T., Halligey, M., Kioussis, D., and Brady, H. J. M. The action of Bax and bcl-2 on T cell selection. J. Exp. Med., 188: 1125-1133, 1998.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1125-1133
-
-
Williams, O.1
Norton, T.2
Halligey, M.3
Kioussis, D.4
Brady, H.J.M.5
-
33
-
-
0030888664
-
BCL-2 antisense therapy in patients with non-Hodgkin lymphoma
-
Webb, A., Cunningham, D., Cotter, F., Clarke, P. A., di Stefano, F., Ross, P., Corbo, M., and Dziewanowska, Z. BCL-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet, 349: 1137-1141, 1997.
-
(1997)
Lancet
, vol.349
, pp. 1137-1141
-
-
Webb, A.1
Cunningham, D.2
Cotter, F.3
Clarke, P.A.4
Di Stefano, F.5
Ross, P.6
Corbo, M.7
Dziewanowska, Z.8
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