메뉴 건너뛰기




Volumn 5, Issue 10, 1999, Pages 2891-2898

Progression to androgen independence is delayed by adjuvant treatment with antisense Bcl-2 oligodeoxynucleotides after castration in the LNCaP prostate tumor model

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; PROTEIN BCL 2;

EID: 0032741282     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (174)

References (42)
  • 1
    • 0027369623 scopus 로고
    • Overview of phase III trials on combined androgen treatment in patients with metastatic prostate cancer
    • Denis, L., and Murphy, G. P. Overview of phase III trials on combined androgen treatment in patients with metastatic prostate cancer. Cancer (Phila.), 72 (Suppl): 3888-3895, 1993.
    • (1993) Cancer (Phila.) , vol.72 , Issue.SUPPL. , pp. 3888-3895
    • Denis, L.1    Murphy, G.P.2
  • 2
    • 0027532535 scopus 로고
    • Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer
    • Yagoda, A., and Petrylak, D. Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer. Cancer (Phila.). 71 (Suppl. 3): 1098-1109, 1993.
    • (1993) Cancer (Phila.). , vol.71 , Issue.SUPPL. 3 , pp. 1098-1109
    • Yagoda, A.1    Petrylak, D.2
  • 3
    • 0009607381 scopus 로고    scopus 로고
    • Growth regulation of normal and malignant prostatic cells
    • Murphy, Griffiths, Denis, Khoury, Chatelain, and Cockett (eds.), Scientific Communication International Ltd.
    • Isaacs, J. Growth regulation of normal and malignant prostatic cells. First International Consultation on Prostate Cancer. In: Murphy, Griffiths, Denis, Khoury, Chatelain, and Cockett (eds.), Scientific Communication International Ltd., 1996.
    • (1996) First International Consultation on Prostate Cancer.
    • Isaacs, J.1
  • 4
    • 0026602518 scopus 로고
    • Serum prostate-specific antigen levels in mice bearing human prostate LNCaP tumors are determined by tumor volume and endocrine and growth factors
    • Gleave, M., Hsieh, J. T., Wu, H. C., von Eschenbach, A. C., and Chung, L. W. Serum prostate-specific antigen levels in mice bearing human prostate LNCaP tumors are determined by tumor volume and endocrine and growth factors. Cancer Res., 52: 1598-1605, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 1598-1605
    • Gleave, M.1    Hsieh, J.T.2    Wu, H.C.3    Von Eschenbach, A.C.4    Chung, L.W.5
  • 5
    • 0027287757 scopus 로고
    • Autocrine regulation of prostate-specific antigen gene expression in human prostate cells
    • Hsieh, J., Wu, H., Gleave, M., von Eschenbach, A., and Chung, L. Autocrine regulation of prostate-specific antigen gene expression in human prostate cells. Cancer Res., 53: 2852-2859, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 2852-2859
    • Hsieh, J.1    Wu, H.2    Gleave, M.3    Von Eschenbach, A.4    Chung, L.5
  • 6
    • 0023797337 scopus 로고
    • Gene expression during the early phases of regression of the androgen-dependent Shionogi mouse mammary carcinoma
    • Rennie, P., Bruchovsky, N., Buttyan, R., Benson, M., and Cheng, H. Gene expression during the early phases of regression of the androgen-dependent Shionogi mouse mammary carcinoma. Cancer Res., 48: 6309, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 6309
    • Rennie, P.1    Bruchovsky, N.2    Buttyan, R.3    Benson, M.4    Cheng, H.5
  • 7
    • 0028040019 scopus 로고
    • bcl-2 and the regulation of programmed cell death
    • Reed, J. C. bcl-2 and the regulation of programmed cell death. J. Cell Biol., 124; 1-6, 1994.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 8
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the bcl-2 family and cell death
    • Yang, E., Korsemeyer, S. J. Molecular thanatopsis: a discourse on the bcl-2 family and cell death. Blood, 88: 386-401, 1996.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsemeyer, S.J.2
  • 9
    • 0025204548 scopus 로고
    • bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery, D., Nunez, G., Milliman, C., Schreiber, R. D., and Korsmeyer, S. J. bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature (Lond.), 348: 334-336, 1990.
    • (1990) Nature (Lond.) , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 10
    • 0025255538 scopus 로고
    • Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
    • Nunez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J. P., and Korsmeyer, S. J. Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol., 144: 3602-3610, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 3602-3610
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    McKearn, J.P.5    Korsmeyer, S.J.6
  • 11
    • 0024454762 scopus 로고
    • Stress-resistance conferred by a high level of bcl-2 α protein in human B lymphoblastoid cell
    • Tsujimoto, Y. Stress-resistance conferred by a high level of bcl-2 α protein in human B lymphoblastoid cell. Oncogene. 4: 1331-1336, 1989.
    • (1989) Oncogene. , vol.4 , pp. 1331-1336
    • Tsujimoto, Y.1
  • 12
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita, T., and Reed, J. C. bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood. 81: 151-157, 1993.
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 13
    • 0031045967 scopus 로고    scopus 로고
    • bcl-2 overexpression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells
    • Kyprianou, N., King, E. D., Bradbury, D., and Rhee, J. G. bcl-2 overexpression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells. Int. J. Cancer. 70: 341-348, 1997.
    • (1997) Int. J. Cancer. , vol.70 , pp. 341-348
    • Kyprianou, N.1    King, E.D.2    Bradbury, D.3    Rhee, J.G.4
  • 14
    • 0029819406 scopus 로고    scopus 로고
    • Protein expression of p53, bcl-2, and KI-67 (MIB-1) as prognostic biomarkers in patients with surgically treated, clinically localized prostate cancer
    • Moul, J. W., Bettencourt, M. C., Sesterhenn, I. A., Mostofi, F. K., McLeod, D. G., Srivastava, S., and Bauer, J. J. Protein expression of p53, bcl-2, and KI-67 (MIB-1) as prognostic biomarkers in patients with surgically treated, clinically localized prostate cancer. Surgery, 120: 159-166, 1996.
    • (1996) Surgery , vol.120 , pp. 159-166
    • Moul, J.W.1    Bettencourt, M.C.2    Sesterhenn, I.A.3    Mostofi, F.K.4    McLeod, D.G.5    Srivastava, S.6    Bauer, J.J.7
  • 16
    • 0030099106 scopus 로고    scopus 로고
    • bcl-2 expression on prostate cancer and its relationship to cell cycle and prognosis
    • Matsushima, H., Hosaka, Y., Suzuki, M., Mizutani, T., Ishizuka, H., and Kawabe, K. bcl-2 expression on prostate cancer and its relationship to cell cycle and prognosis. Int. J. Urol., 3: 113-117, 1996.
    • (1996) Int. J. Urol. , vol.3 , pp. 113-117
    • Matsushima, H.1    Hosaka, Y.2    Suzuki, M.3    Mizutani, T.4    Ishizuka, H.5    Kawabe, K.6
  • 17
    • 0031012825 scopus 로고    scopus 로고
    • Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen-independent prostate cancer
    • McDonnell, T. J., Navone, N. M., Troncoso, P., Pisters, L. L., Conti, C., von Eschenbach, A. C., Brisbay, S., and Logothetis, C. J. Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen-independent prostate cancer. J. Urol., 157: 569-574, 1997.
    • (1997) J. Urol. , vol.157 , pp. 569-574
    • McDonnell, T.J.1    Navone, N.M.2    Troncoso, P.3    Pisters, L.L.4    Conti, C.5    Von Eschenbach, A.C.6    Brisbay, S.7    Logothetis, C.J.8
  • 18
    • 0029077281 scopus 로고
    • Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo
    • Raffo, A. J., Perlman, H., Chen, M. W., Day, M. L., Streitman, J. S., and Buttyan, R. Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo. Cancer Res., 55: 4438-4445, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4438-4445
    • Raffo, A.J.1    Perlman, H.2    Chen, M.W.3    Day, M.L.4    Streitman, J.S.5    Buttyan, R.6
  • 19
    • 0028117635 scopus 로고
    • Pharmacokinetics, tissue distribution, and stability of antisense oligonucleotide phosphorothioate ISIS 3466 in mice
    • Saijo, Y., Perlaky, L., Wang, H., and Busch, H. Pharmacokinetics, tissue distribution, and stability of antisense oligonucleotide phosphorothioate ISIS 3466 in mice. Oncol. Res., 6: 243-249, 1994.
    • (1994) Oncol. Res. , vol.6 , pp. 243-249
    • Saijo, Y.1    Perlaky, L.2    Wang, H.3    Busch, H.4
  • 21
    • 0025875889 scopus 로고
    • Acceleration of human prostate carcinoma growth in vivo by factors produced by prostate and bone fibroblasts
    • Cleave, M. E., Hsieh, J. T., Gao, C., von Eschenbach, A. C., and Chung, L. W. K. Acceleration of human prostate carcinoma growth in vivo by factors produced by prostate and bone fibroblasts. Cancer Res., 51: 3753-3761, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 3753-3761
    • Cleave, M.E.1    Hsieh, J.T.2    Gao, C.3    Von Eschenbach, A.C.4    Chung, L.W.K.5
  • 22
    • 0030152008 scopus 로고    scopus 로고
    • Intermittent androgen suppression delays progression to androgen-independent regulation of prostate-specific antigen gene in the LNCaP prostate tumor model
    • Sato, N., Gleave, M. E., Bruchovsky, N., Rennie, P. S., Goldenberg, S. L., Lange, P. L., and Sullivan, L. D. Intermittent androgen suppression delays progression to androgen-independent regulation of prostate-specific antigen gene in the LNCaP prostate tumor model. J. Steroid Biochem. Mol. Biol., 58: 139-146, 1996.
    • (1996) J. Steroid Biochem. Mol. Biol. , vol.58 , pp. 139-146
    • Sato, N.1    Gleave, M.E.2    Bruchovsky, N.3    Rennie, P.S.4    Goldenberg, S.L.5    Lange, P.L.6    Sullivan, L.D.7
  • 23
    • 0030031962 scopus 로고    scopus 로고
    • Prostatic cell lineage markers: Emergence of bcl2 cells of human prostate cancer xenograft LuCaP 23 following castration
    • Liu, A., Grey, E., Bladou, F., Lange, P., and Vessella, R. Prostatic cell lineage markers: emergence of bcl2 cells of human prostate cancer xenograft LuCaP 23 following castration. Int. J. Cancer, 65: 85-89, 1996.
    • (1996) Int. J. Cancer , vol.65 , pp. 85-89
    • Liu, A.1    Grey, E.2    Bladou, F.3    Lange, P.4    Vessella, R.5
  • 24
    • 0023612470 scopus 로고
    • Gene induction by γ irradiation leads to DNA fragmentation in lymphocytes
    • Sellins, K., and Cohen, J. Gene induction by γ irradiation leads to DNA fragmentation in lymphocytes. J. Immunol., 39: 3199-3206, 1987.
    • (1987) J. Immunol. , vol.39 , pp. 3199-3206
    • Sellins, K.1    Cohen, J.2
  • 25
    • 0032104814 scopus 로고    scopus 로고
    • Prevention of LNCaP prostate tumor growth and progression by isobutyratnide, and orally bioavailable butyrate analogue
    • Gleave, M. E., Sato, N., Rennie, P., and Bruchovsky, N. Prevention of LNCaP prostate tumor growth and progression by isobutyratnide, and orally bioavailable butyrate analogue. J. Cell. Biochem., 69: 271-281, 1998.
    • (1998) J. Cell. Biochem. , vol.69 , pp. 271-281
    • Gleave, M.E.1    Sato, N.2    Rennie, P.3    Bruchovsky, N.4
  • 26
    • 0029977448 scopus 로고    scopus 로고
    • Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
    • Monia, B. P., Johnston, J. F., Geiger, T., Muller, M., and Fabbro, D. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat. Med., 2: 668-675, 1996.
    • (1996) Nat. Med. , vol.2 , pp. 668-675
    • Monia, B.P.1    Johnston, J.F.2    Geiger, T.3    Muller, M.4    Fabbro, D.5
  • 28
    • 0030841919 scopus 로고    scopus 로고
    • Androgenic induction of prostate-specific gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-jun in the human prostate cancer cell line LNCaP
    • Sato, N., Satar, M., Bruchovsky, N., Rennie, P., Saatcioglu, F., Sato, S., Lange, P., and Gleave, M. Androgenic induction of prostate-specific gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-jun in the human prostate cancer cell line LNCaP. J. Biol. Chem., 272: 17485-17494, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17485-17494
    • Sato, N.1    Satar, M.2    Bruchovsky, N.3    Rennie, P.4    Saatcioglu, F.5    Sato, S.6    Lange, P.7    Gleave, M.8
  • 29
    • 0030807543 scopus 로고    scopus 로고
    • Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence
    • Ziegler, A., Luedke, G. H., Fabbro, D., Altmann, K-H., Stahel, R. A., and Zangemeister-Wittke, U. Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence. J. Natl. Cancer Inst., 89: 1027-1035, 1997.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1027-1035
    • Ziegler, A.1    Luedke, G.H.2    Fabbro, D.3    Altmann, K.-H.4    Stahel, R.A.5    Zangemeister-Wittke, U.6
  • 31
    • 0030822629 scopus 로고    scopus 로고
    • Development of a hammerhead ribozyme against bcl-2. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer
    • Dorai, T., Olsson, C. A., Katz, A. E., and Buttyan, R. Development of a hammerhead ribozyme against bcl-2. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer. Prostate, 32: 246-258, 1997.
    • (1997) Prostate , vol.32 , pp. 246-258
    • Dorai, T.1    Olsson, C.A.2    Katz, A.E.3    Buttyan, R.4
  • 33
    • 0033567003 scopus 로고    scopus 로고
    • Antisense Bcl-2 oligodeoxynucleotides inhibit progression to androgen independence after castration in the shionogi tumor model
    • Miyake, H., Tolcher, A., Gleave, M. E. Antisense Bcl-2 oligodeoxynucleotides inhibit progression to androgen independence after castration in the shionogi tumor model. Cancer Res., 59: 4030-4034, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 4030-4034
    • Miyake, H.1    Tolcher, A.2    Gleave, M.E.3
  • 34
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents: Is the bullet really magical?
    • Stein, C. A., and Cheng, Y-C. Antisense oligonucleotides as therapeutic agents: is the bullet really magical? Science (Washington, DC), 267; 1004-1012, 1993.
    • (1993) Science (Washington, DC) , vol.267 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.-C.2
  • 35
    • 0028806487 scopus 로고
    • Does antisense exist?
    • Stein, C. A. Does antisense exist? Nat. Med., 1: 1119-1121, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 1119-1121
    • Stein, C.A.1
  • 36
    • 0030900680 scopus 로고    scopus 로고
    • Immunostimulatory oligonucleotides containing CpG motifs enhance the efficacy of monoclonal therapy of lymphoma
    • Wooldridge, J. E., Ballas, Z., Krieg, A. M., and Weiner, G. J. Immunostimulatory oligonucleotides containing CpG motifs enhance the efficacy of monoclonal therapy of lymphoma. Blood, 89: 2994-2998, 1997.
    • (1997) Blood , vol.89 , pp. 2994-2998
    • Wooldridge, J.E.1    Ballas, Z.2    Krieg, A.M.3    Weiner, G.J.4
  • 37
    • 0029619816 scopus 로고
    • Kinetic characteristics of Escherichia coli RNase HI: Cleavage of various antisense oligonucleotide-RNA duplexes
    • Crooke, S. T., Lemonidis, K. L., Neilson, L., Griffey, R., Lesnik, E. A., and Monia, B. P. Kinetic characteristics of Escherichia coli RNase HI: cleavage of various antisense oligonucleotide-RNA duplexes. Bioehem. J., 312: 599-608, 1995.
    • (1995) Bioehem. J. , vol.312 , pp. 599-608
    • Crooke, S.T.1    Lemonidis, K.L.2    Neilson, L.3    Griffey, R.4    Lesnik, E.A.5    Monia, B.P.6
  • 38
    • 0026573769 scopus 로고
    • Phosphorothioate oligonucleotides are inhibitors of human DNA polymerase and RNase H: Implications for antisense technology
    • Gao, W. Y., Han, F-S., Storm, C., Egan, W., and Cheng, Y. C. Phosphorothioate oligonucleotides are inhibitors of human DNA polymerase and RNase H: implications for antisense technology. Mol. Pharmacol., 41: 223-230, 1991.
    • (1991) Mol. Pharmacol. , vol.41 , pp. 223-230
    • Gao, W.Y.1    Han, F.-S.2    Storm, C.3    Egan, W.4    Cheng, Y.C.5
  • 39
    • 0028815149 scopus 로고
    • Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
    • Guvakova, M. A., Yakubov, L. A., Vlodabsky, I., Tonkinson, J. L., and Stein, C. A. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J. Biol. Chem., 270: 2620-2627, 1994.
    • (1994) J. Biol. Chem. , vol.270 , pp. 2620-2627
    • Guvakova, M.A.1    Yakubov, L.A.2    Vlodabsky, I.3    Tonkinson, J.L.4    Stein, C.A.5
  • 40
    • 0025246690 scopus 로고
    • Effects of androgen withdrawal on the stem cell composition of the Shionogi carcinoma
    • Bruchovsky, N., Rennie, P. S., Coldman, A. J., Goldenberg, S. L., To, M., and Lawson, D. Effects of androgen withdrawal on the stem cell composition of the Shionogi carcinoma. Cancer Res., 50: 2275-2282, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 2275-2282
    • Bruchovsky, N.1    Rennie, P.S.2    Coldman, A.J.3    Goldenberg, S.L.4    To, M.5    Lawson, D.6
  • 41
    • 0019254148 scopus 로고
    • Human prostatic adenocarcinoma. Some characteristics of a serially transplantable line in nude mice (PC-82)
    • Hoehn, W., Schroeder, F., Riemann, J., Joebsis, A., and Hermanek, P. Human prostatic adenocarcinoma. Some characteristics of a serially transplantable line in nude mice (PC-82). Prostate, 1: 95, 1980.
    • (1980) Prostate , vol.1 , pp. 95
    • Hoehn, W.1    Schroeder, F.2    Riemann, J.3    Joebsis, A.4    Hermanek, P.5
  • 42
    • 0027217084 scopus 로고
    • Apoptotic death in epithelial cells; cleavage of DNA to 300 and/or 50-kb fragments prior to or in the absence of internucleosomal fragmentation
    • Oberhammer, F., Wilson, J. W., Dive, C., Morris, I. D., Hickman, J. A., Wakeling, A. E., Walker, P. R., and Sikorska, M. Apoptotic death in epithelial cells; cleavage of DNA to 300 and/or 50-kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J., 12: 3679-3684, 1993.
    • (1993) EMBO J. , vol.12 , pp. 3679-3684
    • Oberhammer, F.1    Wilson, J.W.2    Dive, C.3    Morris, I.D.4    Hickman, J.A.5    Wakeling, A.E.6    Walker, P.R.7    Sikorska, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.