Gene expression profile of oxidant stress and neurodegeneration in transgenic mice deficient in α-tocopherol transfer protein

Free Radical Biology and Medicine

Volumn 35, Issue 11, 2003, Pages 1343-1354

  Gohil, Kishorchandra ^a   Schock, Bettina C ^a   Chakraborty, Abhishek A ^b   Terasawa, Yuko ^c   Raber, Jacob ^c   Farese Jr , Robert V ^c   Packer, Lester ^d   Cross, Carroll E ^a   Traber, Maret G ^e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b M S UNIVERSITY OF BARODA   (India)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e OREGON STATE UNIVERSITY   (United States)

Author keywords

Antioxidant; Anxiety; Free radicals; Long term potentiation; Neurodegeneration; Oligonucleotide arrays; Synapse; Vitamin E

Indexed keywords

ALPHA SYNUCLEIN; ALPHA TOCOPHEROL; ALPHA TOCOPHEROL TRANSFER PROTEIN; APOPTOSIS INHIBITOR; BETA SYNUCLEIN; BINDING PROTEIN; CARRIER PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELIN PROTEIN; PROTEIN KINASE C; RETINOIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ALPHA TOCOPHEROL DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; BRAIN CORTEX; BRAIN ELECTROPHYSIOLOGY; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE EXPRESSION PROFILING; GENE INDUCTION; GENE MUTATION; GENE REPRESSION; GENETIC CODE; GENOME; KNOCKOUT MOUSE; LEWY BODY; LIVER; LIVER CELL; MALE; MOTOR COORDINATION; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVE DEGENERATION; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; TRANSGENIC ANIMAL; UNINDEXED SEQUENCE;

MUS MUSCULUS;

EID: 0344443228     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(03)00509-4     Document Type: Article

References (60)

1. Bell E.F. History of vitamin E in infant nutrition. Am. J. Clin. Nutr. 46:1987;183-186.
2. Kaempf-Rotzoll D.E., Igarashi K., Aoki J., Jishage K., Suzuki H., Tamai H., Linderkamp O., Arai H. Alpha-tocopherol transfer protein is specifically localized at the implantation site of pregnant mouse uterus. Biol. Reprod. 67:2002;599-604.
3. Brigelius-Flohe R., Traber M.G. Vitamin E function and metabolism . FASEB J. 13:1999;1145-1155.
4. Azzi A., Ricciarelli R., Zingg J.M. Nonantioxidant molecular functions of α-tocopherol (vitamin E). FEBS Lett. 519:2002;8-10.
5. Yamauchi J., Iwamoto T., Kida S., Masushige S., Yamada K., Esashi T. Tocopherol-associated protein is a ligand-dependent transcriptional activator. Biochem. Biophys. Res. Commun. 285:2001;295-299.
6. Traber M.G., Arai H. Molecular mechanisms of vitamin E transport. Annu. Rev. Nutr. 19:1999;343-355.
7. Sato Y., Arai H., Miyata A., Tokita S., Yamamoto K., Tanabe T., Inoue K. Primary structure of α-tocopherol transfer protein from rat liver. Homology with cellular retinaldehyde-binding protein. J. Biol. Chem. 268:1993;17705-17710.
8. Arita M., Sato Y., Miyata A., Tanabe T., Takahashi E., Kayden H.J., Arai H., Inoue K. Human α-tocopherol transfer protein cDNA cloning, expression, and chromosomal localization . Biochem. J. 306:1995;437-443.
9. Zimmer S., Stocker A., Sarbolouki M.N., Spycher S.E., Sassoon J., Azzi A. A novel human tocopherol-associated protein cloning, in vitro expression, and characterization . J. Biol. Chem. 275:2000;25672-25680.
10. Sha B., Phillips S.E., Bankaitis V.A., Luo M. Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein. Nature. 391:1998;506-510.
11. Shibata N., Arita M., Misaki Y., Dohmae N., Takio K., Ono T., Inoue K., Arai H. Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis. Proc. Natl. Acad. Sci. USA. 98:2001;2244-2249.
12. Singh D.K., Mokashi V., Elmore C.L., Porter T.D. Phosphorylation of supernatant protein factor enhances its ability to stimulate microsomal squalene monooxygenase. J. Biol. Chem. 278:2003;5646-5651.
13. Yokota T., Shiojiri T., Gotoda T., Arita M., Arai H., Ohga T., Kanda T., Suzuki J., Imai T., Matsumoto H., Harino S., Kiyosawa M., Mizusawa H., Inoue K. Friedreich-like ataxia with retinitis pigmentosa caused by the His101Gln mutation of the α-tocopherol transfer protein gene. Ann. Neurol. 41:1997;826-832.
14. Terasawa Y., Ladha Z., Leonard S.W., Morrow J.D., Newland D., Sanan D., Packer L., Traber M.G., Farese R.V. Jr. Increased atherosclerosis in hyperlipidemic mice deficient in α-tocopherol transfer protein and vitamin E. Proc. Natl. Acad. Sci. USA. 97:2000;13830-13834.
15. Yokota T., Igarashi K., Uchihara T., Jishage K., Tomita H., Inaba A., Li Y., Arita M., Suzuki H., Mizusawa H., Arai H. Delayed-onset ataxia in mice lacking α-tocopherol transfer protein model for neuronal degeneration caused by chronic oxidative stress . Proc. Natl. Acad. Sci. USA. 98:2001;15185-15190.
16. Leonard S.W., Terasawa Y., Farese R.V. Jr., Traber M.G. Incorporation of deuterated RRR- or all-rac-α-tocopherol in plasma and tissues of α-tocopherol transfer protein-null mice. Am. J. Clin. Nutr. 75:2002;555-560.
17. Raber J., Akana S.F., Bhatnagar S., Dallman M.F., Wong D., Mucke L. Hypothalamic-pituitary-adrenal dysfunction in ApoE(-/-) mice possible role in behavioral and metabolic alterations . J. Neurosci. 20:2000;2064-2071.
18. Gohil K., Moy R.K., Farzin S., Maguire J.J., Packer L. mRNA expression profile of a human cancer cell line in response to Ginkgo biloba extract induction of antioxidant response and the Golgi system . Free Radic. Res. 33:2000;831-849.
19. Watanabe C.M., Wolffram S., Ader P., Rimbach G., Packer L., Maguire J.J., Schultz P.G., Gohil K. The in vivo neuromodulatory effects of the herbal medicine ginkgo biloba. Proc. Natl. Acad. Sci. USA. 98:2001;6577-6580.
20. Lockhart D.J., Dong H., Byrne M.C., Follettie M.T., Gallo M.V., Chee M.S., Mittmann M., Wang C., Kobayashi M., Horton H., Brown E.L. Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat. Biotechnol. 14:1996;1675-1680.
21. Thibault C., Lai C., Wilke N., Duong B., Olive M.F., Rahman S., Dong H., Hodge C.W., Lockhart D.J., Miles M.F. Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. Mol. Pharmacol. 58:2000;1593-1600.
22. Quandt K., Frech K., Karas H., Wingender E., Werner T. MatInd and MatInspector new fast and versatile tools for detection of consensus matches in nucleotide sequence data . Nucleic Acids Res. 23:1995;4878-4884.
23. Zheng H., Berman N.E., Klaassen C.D. Chemical modulation of metallothionein I and III mRNA in mouse brain. Neurochem. Int. 27:1995;43-58.
24. Gohil K., Cross C.E., Last J.A. Ozone-induced disruptions of lung transcriptomes. Biochem. Biophys. Res. Commun. 305:2003;719-728.
25. Noveroske J.K., Lai L., Gaussin V., Northrop J.L., Nakamura H., Hirschi K.K., Justice M.J. Quaking is essential for blood vessel development. Genesis. 32:2002;218-230.
26. Gendron R.L., Adams L.C., Paradis H. Tubedown-1, a novel acetyltransferase associated with blood vessel development. Dev. Dyn. 218:2000;300-315.
27. Chajara A., Raoudi M., Delpech B., Levesque H. The fibroproliferative response of arterial smooth muscle cells to balloon catheter injury is associated with increased hyaluronidase production and hyaluronan degradation. Atherosclerosis. 157:2001;293-300.
28. Fischer A., Pallauf J., Gohil K., Weber S.U., Packer L., Rimbach G. Effect of selenium and vitamin E deficiency on differential gene expression in rat liver. Biochem. Biophys. Res. Commun. 285:2001;470-475.
29. Kong A.N., Owuor E., Yu R., Hebbar V., Chen C., Hu R., Mandlekar S. Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). Drug Metab. Rev. 33:2001;255-271.
30. Buetler T.M., Gallagher E.P., Wang C., Stahl D.L., Hayes J.D., Eaton D.L. Induction of phase I and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin, and oltipraz. Toxicol. Appl. Pharmacol. 135:1995;45-57.
31. Danielson P.B. The cytochrome P450 superfamily biochemistry, evolution, and drug metabolism in humans . Curr. Drug Metab. 3:2002;561-597.
32. Hayes J.D., Pulford D.J. The glutathione S-transferase supergene family regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance . Crit. Rev. Biochem. Mol. Biol. 30:1995;445-600.
33. Davis W. Jr., Ronai Z., Tew K.D. Cellular thiols and reactive oxygen species in drug-induced apoptosis. J. Pharmacol. Exp. Ther. 296:2001;1-6.
34. Volm M. Multidrug resistance and its reversal. Anticancer Res. 18:1998;2905-2917.
35. Ibrahim W., Lee U.S., Yeh C.C., Szabo J., Bruckner G., Chow C.K. Oxidative stress and antioxidant status in mouse liver effects of dietary lipid, vitamin E, and iron . J. Nutr. 127:1997;1401-1406.
36. Roy S., Lado B.H., Khanna S., Sen C.K. Vitamin E sensitive genes in the developing rat fetal brain a high-density oligonucleotide microarray analysis . FEBS Lett. 530:2002;17-23.
37. Steinmayr M., Andre E., Conquet F., Rondi-Reig L., Delhaye-Bouchaud N., Auclair N., Daniel H., Crepel F., Mariani J., Sotelo C., Becker-Andre M. Staggerer phenotype in retinoid-related orphan receptor α-deficient mice. Proc. Natl. Acad. Sci. USA. 95:1998;3960-3965.
38. Goodall G., Gheusi G. Abnormal patterns of maze patrolling in the mutant mouse staggerer. Behav. Neural Biol. 47:1987;307-320.
39. Thompson C.C., Potter G.B. Thyroid hormone action in neural development. Cereb. Cortex. 10:2000;939-945.
40. Garcia-Atares N., San Jose I., Cabo R., Vega J.A., Represa J. Changes in the cerebellar cortex of hairless Rhino-J mice (hr-rh-j). Neurosci. Lett. 256:1998;13-16.
41. Gollan L., Sabanay H., Poliak S., Berglund E.O., Ranscht B., Peles E. Retention of a cell adhesion complex at the paranodal junction requires the cytoplasmic region of Caspr. J. Cell Biol. 157:2002;1247-1256.
42. Spillantini M.G., Schmidt M.L., Lee V.M., Trojanowski J.Q., Jakes R., Goedert M. Alpha-synuclein in Lewy bodies. Nature. 388:1997;839-840.
43. Goedert M. Alpha-synuclein and neurodegenerative diseases. Nat. Rev. Neurosci. 2:2001;492-501.
44. Cummings J.L. Lewy body diseases with dementia pathophysiology and treatment . Brain Cogn. 28:1995;266-280.
45. Uversky V.N., Li J., Souillac P., Millett I.S., Doniach S., Jakes R., Goedert M., Fink A.L. Biophysical properties of the synucleins and their propensities to fibrillate inhibition of α-synuclein assembly by β- and γ-synucleins . J. Biol. Chem. 277:2002;11970-11978.
46. Hashimoto M., Rockenstein E., Mante M., Mallory M., Masliah E. Beta-synuclein inhibits α-synuclein aggregation a possible role as an anti-parkinsonian factor . Neuron. 32:2001;213-223.
47. Junn E., Mouradian M.M. Human α-synuclein overexpression increases intracellular reactive oxygen species levels and susceptibility to dopamine. Neurosci. Lett. 320:2002;146-150.
48. Chandra D., Liu J.W., Tang D.G. Early mitochondrial activation and cytochrome c upregulation during apoptosis. J. Biol. Chem. 277:2002;50842-50854.
49. Cerghet M., Bessert D.A., Nave K.A., Skoff R.P. Differential expression of apoptotic markers in jimpy and in Plp overexpressors evidence for different apoptotic pathways . J. Neurocytol. 30:2001;841-855.
50. Sokol R.J., Kayden H.J., Bettis D.B., Traber M.G., Neville H., Ringel S., Wilson W.B., Stumpf D.A. Isolated vitamin E deficiency in the absence of fat malabsorption - familial and sporadic cases characterization and investigation of causes . J. Lab. Clin. Med. 111:1988;548-559.
51. Marz K.E., Hanson P.I. Sealed with a twist complexin and the synaptic SNARE complex . Trends Neurosci. 25:2002;381-383.
52. Sheng M., Kim M.J. Postsynaptic signaling and plasticity mechanisms. Science. 298:2002;776-780.
53. Shobe J. The role of PKA, CaMKII, and PKC in avoidance conditioning permissive or instructive? Neurobiol. Learn Mem. 77:2002;291-312.
54. Anderson M.F., Aberg M.A., Nilsson M., Eriksson P.S. Insulin-like growth factor-I and neurogenesis in the adult mammalian brain. Brain Res. Dev. Brain Res. 134:2002;115-122.
55. Floyd R.A., Hensley K. Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol. Aging. 23:2002;795-807.
56. Grodstein F., Chen J., Willett W.C. High-dose antioxidant supplements and cognitive function in community-dwelling elderly women. Am. J. Clin. Nutr. 77:2003;975-984.
57. Chen C., Tonegawa S. Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain. Annu. Rev. Neurosci. 20:1997;157-184.
58. Vasar E., Harro J., Lang A., Soosaar A., Oopik T., Koks S., Sihver S., Volke V. Anti-exploratory effect of N-methyl-D-aspartate in elevated plus-maze. Involvement of NMDA and CCK receptors. Eur. Neuropsychopharmacol. 3:1993;63-73.
59. Falzone T.L., Gelman D.M., Young J.I., Grandy D.K., Low M.J., Rubinstein M. Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear. Eur. J. Neurosci. 15:2002;158-164.
60. Perez R.G., Waymire J.C., Lin E., Liu J.J., Guo F., Zigmond M.J. A role for α-synuclein in the regulation of dopamine biosynthesis. J. Neurosci. 22:2002;3090-3099.