Physicochemical and biological characterization of polyethylenimine-graft- poly(ethylene glycol) block copolymers as a delivery system for oligonucleotides and ribozymes

Bioconjugate Chemistry

Volumn 15, Issue 4, 2004, Pages 677-684

  Brus, Carola ^a   Petersen, Holger ^a   Aigner, Achim ^b   Czubayco, Frank ^b   Kissel, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b Fachbereich Medizin der Universitat Marburg   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; BIOCOMPATIBILITY; BLOCK COPOLYMERS; CELL CULTURE; CHAINS; CHEMICAL ACTIVATION; CONTROLLED DRUG DELIVERY; ELECTROPHORESIS; ETHYLENE GLYCOL; FLUORESCENCE SPECTROSCOPY; GRAFTING (CHEMICAL); OLIGONUCLEOTIDES; PHOTON CORRELATION SPECTROSCOPY; POLYETHYLENE OXIDES; POLYOLS; SUSPENSIONS (FLUIDS); TARGETED DRUG DELIVERY; ZETA POTENTIAL;

BIOLOGICAL CHARACTERIZATION; BLOCK CO POLYMERS; COMPLEMENT ACTIVATIONS; DELIVERY SYSTEMS; ENZYMATIC DEGRADATION; INTERPOLYELECTROLYTE COMPLEX; OLIGODEOXYNUCLEOTIDES; PHYSICO-CHEMICAL CHARACTERIZATION; POLY(ETHYLENIMINE); RIBOZYMES;

POLYETHYLENE GLYCOLS;

COPOLYMER; MACROGOL; MACROGOL 25; MACROGOL 550; MESSENGER RNA; NUCLEASE; OLIGONUCLEOTIDE; POLYETHYLENEIMINE BLOCK COPOLYMER; POLYETHYLENEIMINE DERIVATIVE; POLYETHYLENEIMINE GRAFT POLY(ETHYLENE GLYCOL) BLOCK COPOLYMER; RIBOZYME; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; BIOCOMPATIBILITY; CELL CULTURE; COMPLEMENT ACTIVATION; COMPLEX FORMATION; CONTROLLED STUDY; DENSITOMETRY; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; ELECTROPHORESIS; ENZYME DEGRADATION; ENZYME STABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERPOLYELECTROLYTE COMPLEX; LASER DOPPLER ANEMOMETRY; MOLECULAR WEIGHT; PHOTON CORRELATION SPECTROSCOPY; PHYSICAL CHEMISTRY; PROTEIN ANALYSIS; ZETA POTENTIAL;

EID: 3242792582     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc034160m     Document Type: Article

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