Chemokines in Immune Surveillance of the Intestine

Current Topics in Membranes

Volumn 55, Issue , 2005, Pages 143-158

  Hendrik Niess, Jan ^a   Reinecker, Hans Christian ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33645867682     PISSN: 10635823     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1063-5823(04)55006-8     Document Type: Review

References (77)

1. Agace W.W., Amara A., Roberts A.I., Pablos J.L., Thelen S., Uguccioni M., Li X.Y., Marsal J., Arenzana-Seisdedos F., Delaunay T., Ebert E.C., Moser B., and Parker C.M. Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation. Curr. Biol. 10 (2000) 325-328
2. Ancuta P., Rao R., Moses A., Mehle A., Shaw S.K., Luscinskas F.W., and Gabuzda D. Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. J. Exp. Med. 197 (2003) 1701-1707
3. Andres P.G., Beck P.L., Mizoguchi E., Mizoguchi A., Bhan A.K., Dawson T., Kuziel W.A., Maeda N., MacDermott R.P., Podolsky D.K., and Reinecker H.C. Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: Lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine. J. Immunol. 164 (2000) 6303-6312
4. Ansel K.M., Ngo V.N., Hyman P.L., Luther S.A., Forster R., Sedgwick J.D., Browning J.L., Lipp M., and Cyster J.G. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 406 (2000) 309-314
5. Asarnow D.M., Goodman T., LeFrancois L., and Allison J.P. Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells. Nature 341 (1989) 60-62
6. Banks C., Bateman A., Payne R., Johnson P., and Sheron N. Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease. J. Pathol. 199 (2003) 28-35
7. Bazan J.F., Bacon K.B., Hardiman G., Wang W., Soo K., Rossi D., Greaves D.R., Zlotnik A., and Schall T.J. A new class of membrane-bound chemokine with a CX3C motif. Nature 385 (1997) 640-644
8. Berin M.C., Dwinell M.B., Eckmann L., and Kagnoff M.F. Production of MDC/CCL22 by human intestinal epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 280 (2001) G1217-G1226
9. Berrebi D., Banerjee A., Paris R., Potet F., Aigrain Y., Emilie D., Cezard J.P., Hugot J.P., Navarro J., and Peuchmaur M. In situ Rantes and interferon-gamma gene expression in pediatric small bowel Crohn's disease. J. Pediatr. Gastroenterol. Nutr. 25 (1997) 371-376
10. Bowman E.P., Kuklin N.A., Youngman K.R., Lazarus N.H., Kunkel E.J., Pan J., Greenberg H.B., and Butcher E.C. The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells. J. Exp. Med. 195 (2002) 269-275
11. Brand S., Sakaguchi T., Gu X., Colgan S.P., and Reinecker H.C. Fractalkine-mediated signals regulate cell-survival and immune-modulatory responses in intestinal epithelial cells. Gastroenterology 122 (2002) 166-177
12. Breitfeld D., Ohl L., Kremmer E., Ellwart J., Sallusto F., Lipp M., and Forster R. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J. Exp. Med. 192 (2000) 1545-1552
13. Campbell D.J., Debes G.F., Johnston B., Wilson E., and Butcher E.C. Targeting T cell responses by selective chemokine receptor expression. Semin. Immunol. 15 (2003) 277-286
14. Casola A., Estes M.K., Crawford S.E., Ogra P.L., Ernst P.B., Garofalo R.P., and Crowe S.E. Rotavirus infection of cultured intestinal epithelial cells induces secretion of CXC and CC chemokines. Gastroenterology 114 (1998) 947-955
15. D'Amico G., Bianchi G., Bernasconi S., Bersani L., Piemonti L., Sozzani S., Mantovani A., and Allavena P. Adhesion, transendothelial migration, and reverse transmigration of in vitro cultured dendritic cells. Blood 92 (1998) 207-214
16. Daig R., Andus T., Aschenbrenner E., Falk W., Scholmerich J., and Gross V. Increased interleukin-8 expression in the colon mucosa of patients with inflammatory bowel disease. Gut 38 (1996) 216-222
17. Darfeuille-Michaud A., Neut C., Barnich N., Lederman E., Di Martino P., Desreumaux P., Gambiez L., Joly B., Cortot A., and Colombel J.F. Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology 115 (1998) 1405-1413
18. Delezay O., Koch N., Yahi N., Hammache D., Tourres C., Tamalet C., and Fantini J. Co-expression of CXCR4/fusin and galactosylceramide in the human intestinal epithelial cell line HT-29. AIDS 11 (1997) 1311-1318
19. Delgado E., Finkel V., Baggiolini M., Mackay C.R., Steinman R.M., and Granelli-Piperno A. Mature dendritic cells respond to SDF-1, but not to several beta-chemokines. Immunobiology 198 (1998) 490-500
20. Dieu M.C., Vanbervliet B., Vicari A., Bridon J.M., Oldham E., Ait-Yahia S., Briere F., Zlotnik A., Lebecque S., and Caux C. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 188 (1998) 373-386
21. Dwinell M.B., Eckmann L., Leopard J.D., Varki N.M., and Kagnoff M.F. Chemokine receptor expression by human intestinal epithelial cells. Gastroenterology 117 (1999) 359-367
22. Dwinell M.B., Lugering N., Eckmann L., and Kagnoff M.F. Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells. Gastroenterology 120 (2001) 49-59
23. Eckmann L., Kagnoff M.F., and Fierer J. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect. Immun. 61 (1993) 4569-4574
24. Forster R., Mattis A.E., Kremmer E., Wolf E., Brem G., and Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87 (1996) 1037-1047
25. Fusunyan R.D., Quinn J.J., Ohno Y., MacDermott R.P., and Sanderson I.R. Butyrate enhances interleukin (IL)-8 secretion by intestinal epithelial cells in response to IL-1beta and lipopolysaccharide. Pediatr. Res. 43 (1998) 84-90
26. Ganz T. Defensins: Antimicrobial peptides of innate immunity. Nat. Rev. Immunol. 3 (2003) 710-720
27. Garcia-Zepeda E.A., Rothenberg M.E., Ownbey R.T., Celestin J., Leder P., and Luster A.D. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat. Med. 2 (1996) 449-456
28. Geissmann F., Jung S., and Littman D.R. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19 (2003) 71-82
29. Gunn M.D., Tangemann K., Tam C., Cyster J.G., Rosen S.D., and Williams L.T. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl. Acad. Sci. USA 95 (1998) 258-263
30. Hoover D.M., Boulegue C., Yang D., Oppenheim J.J., Tucker K., Lu W., and Lubkowski J. The structure of human macrophage inflammatory protein-3alpha/CCL20: Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins. J. Biol. Chem. 277 (2002) 37647-37654
31. Huang F.P., Platt N., Wykes M., Major J.R., Powell T.J., Jenkins C.D., and MacPherson G.G. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. 191 (2000) 435-444
32. Hugot J.P., Chamaillard M., Zouali H., Lesage S., Cezard J.P., Belaiche J., Almer S., Tysk C., O'Morain C.A., Gassull M., Binder V., Finkel Y., Cortot A., Modigliani R., Laurent-Puig P., Gower-Rousseau C., Macry J., Colombel J.F., Sahbatou M., and Thomas G. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411 (2001) 599-603
33. Iwasaki A., and Kelsall B.L. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin-10 and induce the differentiation of T helper type 2 cells. J. Exp. Med. 190 (1999) 229-239
34. Iwasaki A., and Kelsall B.L. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine. J. Exp. Med. 191 (2000) 1381-1394
35. Izadpanah A., Dwinell M.B., Eckmann L., Varki N.M., and Kagnoff M.F. Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: Mechanism for modulating mucosal immunity. Am. J. Physiol. Gastrointest. Liver. Physiol. 280 (2001) G710-G719
36. Kelsall B.L., Biron C.A., Sharma O., and Kaye P.M. Dendritic cells at the host-pathogen interface. Nat. Immunol. 3 (2002) 699-702
37. Kobayashi H., Miura S., Nagata H., Tsuzuki Y., Hokari R., Ogino T., Watanabe C., Azuma T., and Ishii H. In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes: Relationships to maturation and role of chemokines. J. Leukoc. Biol. 75 (2004) 434-442
38. Kunkel E.J., Campbell J.J., Haraldsen G., Pan J., Boisvert J., Roberts A.I., Ebert E.C., Vierra M.A., Goodman S.B., Genovese M.C., Wardlaw A.J., Greenberg H.B., Parker C.M., Butcher E.C., Andrew D.P., and Agace W.W. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J. Exp. Med. 192 (2000) 761-768
39. Kunkel E.J., Kim C.H., Lazarus N.H., Vierra M.A., Soler D., Bowman E.P., and Butcher E.C. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J. Clin. Invest. 111 (2003) 1001-1010
40. MacDermott R.P., Sanderson I.R., and Reinecker H.C. The central role of chemokines (chemotactic cytokines) in the immunopathogenesis of ulcerative colitis and Crohn's disease. Inflamm. Bowel Dis. 4 (1998) 54-67
41. Maric I., Holt P.G., Perdue M.H., and Bienenstock J. Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat intestine. J. Immunol. 156 (1996) 1408-1414
42. Mazzucchelli L., Hauser C., Zgraggen K., Wagner H.E., Hess M.W., Laissue J.A., and Mueller C. Differential in situ expression of the genes encoding the chemokines MCP-1 and RANTES in human inflammatory bowel disease. J. Pathol. 178 (1996) 201-206
43. Mazzucchelli L., Hauser C., Zgraggen K., Wagner H., Hess M., Laissue J.A., and Mueller C. Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am. J. Pathol. 144 (1994) 997-1007
44. McCormick B.A., Colgan S.P., Delp-Archer C., Miller S.I., and Madara J.L. Salmonella typhimurium attachment to human intestinal epithelial monolayers: Transcellular signalling to subepithelial neutrophils. J. Cell. Biol. 123 (1993) 895-907
45. McCormick B.A., Miller S.I., Carnes D., and Madara J.L. Transepithelial signaling to neutrophils by salmonellae: A novel virulence mechanism for gastroenteritis. Infect. Immun. 63 (1995) 2302-2309
46. Mitsuyama K., Toyonaga A., Sasaki E., Watanabe K., Tateishi H., Nishiyama T., Saiki T., Ikeda H., Tsuruta O., and Tanikawa K. IL-8 as an important chemoattractant for neutrophils in ulcerative colitis and Crohn's disease. Clin. Exp. Immunol. 96 (1994) 432-436
47. Moser B., and Loetscher P. Lymphocyte traffic control by chemokines. Nat. Immunol. 2 (2001) 123-128
48. Muehlhoefer A., Saubermann L.J., Gu X., Luedtke-Heckenkamp K., Xavier R., Blumberg R.S., Podolsky D.K., MacDermott R.P., and Reinecker H.C. Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa. J. Immunol. 164 (2000) 3368-3376
49. Nagler-Anderson C. Man the barrier! Strategic defenses in the intestinal mucosa. Nat. Rev. Immunol. 1 (2001) 59-67
50. Neutra M.R., Frey A., and Kraehenbuhl J.P. Epithelial M cells: Gateways for mucosal infection and immunization. Cell 86 (1996) 345-348
51. Niess J.H., Brand S., Gu X., Landsmann L., Jung S., McCormick B.A., Vyas J.M., Boes M., Ploegh P.L., Fox J.G., Littman D.R., and Reinecker H.C. CX3CRI - mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307 (2005) 254-258
52. Niess J.H., Monnikes H., Dignass A.U., Klapp B.F., and Arck P.C. Review on the influence of stress on immune mediators, neuropeptides and hormones with relevance for inflammatory bowel disease. Digestion 65 (2002) 131-140
53. Ogura Y., Bonen D.K., Inohara N., Nicolae D.L., Chen F.F., Ramos R., Britton H., Moran T., Karaliuskas R., Duerr R.H., Achkar J.P., Brant S.R., Bayless T.M., Kirschner B.S., Hanauer S.B., Nunez G., and Cho J.H. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411 (2001) 603-606
54. Okada T., Ngo V.N., Ekland E.H., Forster R., Lipp M., Littman D.R., and Cyster J.G. Chemokine requirements for B cell entry to lymph nodes and Peyer's patches. J. Exp. Med. 196 (2002) 65-75
55. Pan J., Kunkel E.J., Gosslar U., Lazarus N., Langdon P., Broadwell K., Vierra M.A., Genovese M.C., Butcher E.C., and Soler D. A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues. J. Immunol. 165 (2000) 2943-2949
56. Papadakis K.A., Prehn J., Nelson V., Cheng L., Binder S.W., Ponath P.D., Andrew D.P., and Targan S.R. The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. J. Immunol. 165 (2000) 5069-5076
57. Podolsky D.K. Inflammatory bowel disease. N. Engl. J. Med. 347 (2002) 417-429
58. Reinecker H.C., Loh E.Y., Ringler D.J., Mehta A., Rombeau J.L., and MacDermott R.P. Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa. Gastroenterology 108 (1995) 40-50
59. Rescigno M., Urbano M., Valzasina B., Francolini M., Rotta G., Bonasio R., Granucci F., Kraehenbuhl J.P., and Ricciardi-Castagnoli P. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol. 2 (2001) 361-367
60. Romagnani S. Th1/Th2 cells. Inflamm. Bowel. Dis. 5 (1999) 285-294
61. Sasaki S., Yoneyama H., Suzuki K., Suriki H., Aiba T., Watanabe S., Kawauchi Y., Kawachi H., Shimizu F., Matsushima K., Asakura H., and Narumi S. Blockade of CXCL10 protects mice from acute colitis and enhances crypt cell survival. Eur. J. Immunol. 32 (2002) 3197-3205
62. Savkovic S.D., Koutsouris A., and Hecht G. Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophils. Infect. Immun. 64 (1996) 4480-4487
63. Song F., Ito K., Denning T.L., Kuninger D., Papaconstantinou J., Gourley W., Klimpel G., Balish E., Hokanson J., and Ernst P.B. Expression of the neutrophil chemokine KC in the colon of mice with enterocolitis and by intestinal epithelial cell lines: Effects of flora and proinflammatory cytokines. J. Immunol. 162 (1999) 2275-2280
64. Sozzani S., Allavena P., D'Amico G., Luini W., Bianchi G., Kataura M., Imai T., Yoshie O., Bonecchi R., and Mantovani A. Differential regulation of chemokine receptors during dendritic cell maturation: A model for their trafficking properties. J. Immunol. 161 (1998) 1083-1086
65. Sozzani S., Luini W., Borsatti A., Polentarutti N., Zhou D., Piemonti L., D'Amico G., Power C.A., Wells T.N., Gobbi M., Allavena P., and Mantovani A. Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J. Immunol. 159 (1997) 1993-2000
66. Steinman R.M., Hawiger D., Liu K., Bonifaz L., Bonnyay D., Mahnke K., Iyoda T., Ravetch J., Dhodapkar M., Inaba K., and Nussenzweig M. Dendritic cell function in vivo during the steady state: A role in peripheral tolerance. Ann. New York Acad. Sci. 987 (2003) 15-25
67. Svensson M., Marsal J., Ericsson A., Carramolino L., Broden T., Marquez G., and Agace W.W. CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa. J. Clin. Invest. 110 (2002) 1113-1121
68. Swidsinski A., Ladhoff A., Pernthaler A., Swidsinski S., Loening-Baucke V., Ortner M., Weber J., Hoffmann U., Schreiber S., Dietel M., and Lochs H. Mucosal flora in inflammatory bowel disease. Gastroenterology 122 (2002) 44-54
69. Uguccioni M., Gionchetti P., Robbiani D.F., Rizzello F., Peruzzo S., Campieri M., and Baggiolini M. Increased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis. Am. J. Pathol. 155 (1999) 331-336
70. Uhlig H.H., and Powrie F. Dendritic cells and the intestinal bacterial flora: A role for localized mucosal immune responses. J. Clin. Invest. 112 (2003) 648-651
71. Vainer B., Nielsen O.H., and Horn T. Expression of E-selectin, sialyl Lewis X, and macrophage inflammatory protein-1alpha by colonic epithelial cells in ulcerative colitis. Dig. Dis. Sci. 43 (1998) 596-608
72. Wehkamp J., Harder J., Weichenthal M., Mueller O., Herrlinger K.R., Fellermann K., Schroeder J.M., and Stange E.F. Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis. Inflamm. Bowel Dis. 9 (2003) 215-223
73. Yang D., Biragyn A., Kwak L.W., and Oppenheim J.J. Mammalian defensins in immunity: More than just microbicidal. Trends. Immunol. 23 (2002) 291-296
74. Yang D., Chertov O., Bykovskaia S.N., Chen Q., Buffo M.J., Shogan J., Anderson M., Schroder J.M., Wang J.M., Howard O.M., and Oppenheim J.J. Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286 (1999) 525-528
75. Yang S.K., Eckmann L., Panja A., and Kagnoff M.F. Differential and regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells. Gastroenterology 113 (1997) 1214-1223
76. Z'Graggen K., Walz A., Mazzucchelli L., Strieter R.M., and Mueller C. The C-X-C chemokine ENA-78 is preferentially expressed in intestinal epithelium in inflammatory bowel disease. Gastroenterology 113 (1997) 808-816
77. Zhao X., Sato A., Dela Cruz C.S., Linehan M., Luegering A., Kucharzik T., Shirakawa A.K., Marquez G., Farber J.M., Williams I., and Iwasaki A. CCL9 is secreted by the follicle-associated epithelium and recruits dome region Peyer's patch CD11b+ dendritic cells. J. Immunol. 171 (2003) 2797-2803