The structure of human macrophage inflammatory protein-3α/CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human β-defensins

Journal of Biological Chemistry

Volumn 277, Issue 40, 2002, Pages 37647-37654

  Hoover, David M ^a   Boulègue, Cyril ^b   De Yang, ^c   Oppenheim, Joost J ^d   Tucker, Kenneth ^a   Lu, Wuyuan ^a,b   Lubkowski, Jacek ^a,d,e  

^a Macromolecular Crystallography Laboratory   (United States)

^b Lab of Molecular Immunoregulation   (United States)

^c Developmental Therapeutics Program   (United States)

^d INSTITUTE OF HUMAN VIROLOGY   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CHEMICAL BONDS; FUNGI; PROTEINS; STRUCTURE (COMPOSITION); X RAY CRYSTALLOGRAPHY;

ANTIMICROBIAL PEPTIDES; MACROPHAGES;

BIOCHEMISTRY;

BETA DEFENSIN; CHEMOKINE; CHEMOKINE RECEPTOR CCR6; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA;

ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING SITE; CANDIDA ALBICANS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; DRUG ACTIVITY; ESCHERICHIA COLI; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; STAPHYLOCOCCUS AUREUS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; BETA-DEFENSINS; CHEMOKINES, CC; DIMERIZATION; ESCHERICHIA COLI; HUMANS; MACROPHAGE INFLAMMATORY PROTEINS; MICE; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, CHEMOKINE; RECOMBINANT PROTEINS; STAPHYLOCOCCUS AUREUS;

CANDIDA; CANDIDA ALBICANS; ESCHERICHIA COLI; FUNGI; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0037020263     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M203907200     Document Type: Article

References (74)

1. Rossi, D., and Zlotnik, A. (2000) Annu. Rev. Immunol. 18, 217-242
2. Zlotnik, A., and Yoshie, O. (2000) Immunity 12, 121-127
3. Horuk, R. (2001) Cytokine Growth Factor Rev. 12, 313-335
4. Campbell, J. J., Hedrick, J., Zlotnik, A., Siani, M. A., Thompson, D. A., and Butcher, E. C. (1998) Science 279, 381-384
5. Rossi, D. L., Vicari, A. P., Franz-Bacon, K., McClanahan, T. K., and Zlotnik, A. (1997) J. Immunol. 158, 1033-1036
6. Homey, B., Dieu-Nosjean, M. C., Wiesenborn, A., Massacrier, C., Pin, J. J., Oldham, E., Catron, D., Buchanan, M. E., Müller, A., deWaal, M. R., Deng, G., Orozco, R., Ruzicka, T., Lehmann, P., Lebecque, S., Caux, C., and Zlotnik, A. (2000) J. Immunol. 164, 6621-6632
7. Charbonnier, A. S., Kohrgruber, N., Kriehuber, E., Stingl, G., Rot, A., and Maurer, D. (1999) J. Exp. Med. 190, 1755-1768
8. Tanaka, Y., Imai, T., Baba, M., Ishikawa, I., Uehira, M., Nomiyama, H., and Yoshie, O. (1999) Eur. J. Immunol. 29, 633-642
9. Dieu, M. C., Vanbervliet, B., Vicari, A., Bridon, J. M., Oldham, E., Ait-Yahia, S., Briere, F., Zlotnik, A., Lebecque, S., and Caux, C. (1998) J. Exp. Med. 188, 373-386
10. Iwasaki, A., and Kelsall, B. L. (2000) J. Exp. Med. 191, 1381-1394
11. Cook, D. N., Prosser, D. M., Forster, R., Zhang, J., Kuklin, N. A., Abbondanzo, S. J., Niu, X. D., Chen, S. C., Manfra, D. J., Wiekowski, M. T., Sullivan, L. M., Smith, S. R., Greenberg, H. B., Narula, S. K., Lipp, M., and Lira, S. A. (2000) Immunity 12, 495-503
12. Varona, R., Zaballos, A., Gutierrez, J., Martin, P., Roncal, F., Albar, J. P., Ardavin, C., and Marquez, G. (1998) FEBS Lett. 440, 188-194
13. Power, C. A., Church, D. J., Meyer, A., Alouani, S., Proudfoot, A. E., Clark-Lewis, I., Sozzani, S., Mantovani, A., and Wells, T. N. (1997) J. Exp. Med. 186, 825-835
14. Liao, F., Alderson, R., Su, J., Ullrich, S. J., Kreider, B. L., and Farber, J. M. (1997) Biochem. Biophys. Res. Commun. 236, 212-217
15. Al-Aoukaty, A., Rolstad, B., Giaid, A., and Maghazachi, A. A. (1998) Immunology 95, 618-624
16. Liao, F., Rabin, R. L., Smith, C. S., Sharma, G., Nutman, T. B., and Farber, J. M. (1999) J. Immunol. 162, 186-194
17. Caux, C., Vanbervliet, B., Massacrier, C., Ait-Yahia, S., Vaure, C., Chemin, K., Dieu-Nosjean, M. C., and Vicari, A. (2002) Transplantation 73, S7-S11
18. Shimizu, Y., Murata, H., Kashii, Y., Hirano, K., Kunitani, H., Higuchi, K., and Watanabe, A. (2001) Hepatology 34, 311-319
19. Serafini, B., Columba-Cabezas, S., Di Rosa, F., and Aloisi, F. (2000) Am. J. Pathol. 157, 1991-2002
20. Kawasaki, S., Takizawa, H., Yoneyama, H., Nakayama, T., Fujisawa, R., Izumizaki, M., Imai, T., Yoshie, O., Homma, I., Yamamoto, K., and Matsushima, K. (2001) J. Immunol. 166, 2055-2062
21. Matsui, T., Akahoshi, T., Namai, R., Hashimoto, A., Kurihara, Y., Rana, M., Nishimura, A., Endo, H., Kitasato, H., Kawai, S., Takagishi, K., and Kondo, H. (2001) Clin. Exp. Immunol. 125, 155-161
22. Scheerens, H., Hessel, E., Waal-Malefyt, R., Leach, M. W., and Rennick, D. (2001) Eur. J. Immunol. 31, 1465-1474
23. Lukacs, N. W., Prosser, D. M., Wiekowski, M., Lira, S. A., and Cook, D. N. (2001) J. Exp. Med. 194, 551-555
24. Yang, D., Chertov, O., Bykovskaia, S. N., Chen, Q., Buffo, M. J., Shogan, J., Anderson, M., Schröder, J. M., Wang, J. M., Howard, O. M., and Oppenheim, J. J. (1999) Science 286, 525-528
25. Ganz, T., and Lehrer, R. I. (1998) Curr. Opin. Immunol. 10, 41-44
26. Pérez-Cañadillas, J. M., Zaballos, A., Gutiérrez, J., Varona, R., Roncal, F., Albar, J. P., Márquez, G., and Bruix, M. (2001) J. Biol. Chem. 276, 28372-28379
27. Hoover, D. M., Chertov, O., and Lubkowski, J. (2001) J. Biol. Chem. 276, 39021-39026
28. Hoover, D. M., Rajashankar, K. R., Blumenthal, R., Puri, A., Oppenheim, J. J., Chertov, O., and Lubkowski, J. (2000) J. Biol. Chem. 275, 32911-32918
29. Schnölzer, M., Alewood, P., Jones, A., Alewood, D., and Kent, S. B. H. (1992) Int. J. Pept. Protein Res. 40, 180-193
30. Schutyser, E., Struyf, S., Menten, P., Lenaerts, J. P., Conings, R., Put, W., Wuyts, A., Proost, P., and Van Damme, J. (2000) J. Immunol. 165, 4470-4477
31. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
32. Navaza, J. (1994) Acta Crystallogr. Sect. A 50, 157-163
33. Matthews, B. W. (1968) J. Mol. Biol. 33, 491-497
34. Hoover, D. M., Shaw, J., Gryczynski, Z., Proudfoot, A. E. I., Wells, T., and Lubkowski, J. (2000) Protein Pept. Lett. 7, 73-82
35. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
36. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. Sect. A 47, 110-119
37. Sheldrick, G. M., and Schneider, T. R. (1997) Methods Enzymol. 277, 319-344
38. Carruthers, L. M., Schirf, V. R., Demeler, B., and Hansen, J. C. (2000) Methods Enzymol. 321, 66-80
39. Demeler, B., Behlke, J., and Ristau, O. (2000) Methods Enzymol. 321, 38-66
40. Falk, W., Goodwin, R. H., Jr., and Leonard, E. J. (1980) J. Immunol. Methods 33, 239-247
41. Lilie, H., Schwarz, E., and Rudolph, R. (1998) Curr. Opin. Biotechnol. 9, 497-501
42. Lubkowski, J., Bujacz, G., Boqué, L., Domaille, P. J., Handel, T. M., and Wlodawer, A. (1997) Nat. Struct. Biol. 4, 64-69
43. Harwig, S. S., Ganz, T., and Lehrer, R. I. (1994) Methods Enzymol. 236, 160-172
44. Ramachandran, G. N., and Sasisekharan, V. (1968) Adv. Protein Chem. 23, 283-438
45. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
46. Clore, G. M., and Gronenborn, A. M. (1995) FASEB J. 9, 57-62
47. Baldwin, E. T., Weber, I. T., St. Charles, R., Xuan, J. C., Appella, E., Yamada, M., Matsushima, K., Edwards, B. F., Clore, G. M., and Gronenborn, A. M. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 502-506
48. Crump, M. P., Gong, J. H., Loetscher, P., Rajarathnam, K., Amara, A., Arenzana-Seisdedos, F., Virelizier, J. L., Baggiolini, M., Sykes, B. D., and Clark-Lewis, I. (1997) EMBO J. 16, 6996-7007
49. Clore, G. M., Appella, E., Yamada, M., Matsushima, K., and Gronenborn, A. M. (1990) Biochemistry 29, 1689-1696
50. Nicholls, A., Sharp, K. A., and Honig, B. (1991) Proteins 11, 281-296
51. Dealwis, C., Fernandez, E. J., Thompson, D. A., Simon, R. J., Siani, M. A., and Lolis, E. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6941-6946
52. Meunier, S., Bernassau, J. M., Guillemot, J. C., Ferrara, P., and Darbon, H. (1997) Biochemistry. 36, 4412-4422
53. Ganz, T., Selsted, M. E., Szklarek, D., Harwig, S. S., Daher, K., Bainton, D. F., and Lehrer, R. I. (1985) J. Clin. Invest. 76, 1427-1435
54. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., and Ganz, T. (1998) J. Clin. Invest. 101, 1633-1642
55. Harder, J., Bartels, J., Christophers, E., and Schröder, J. M. (1997) Nature 387, 861
56. Hiratsuka, T., Nakazato, M., Date, Y., Ashitani, J., Minematsu, T., Chino, N., and Matsukura, S. (1998) Biochem. Biophys. Res. Commun. 249, 943-947
57. Hemmerich, S., Paavola, C., Bloom, A., Bhakta, S., Freedman, R., Grunberger, D., Krstenansky, J., Lee, S., McCarley, D., Mulkins, M., Wong, B., Pease, J., Mizoue, L., Mirzadegan, T., Polsky, I., Thompson, K., Handel, T. M., and Jarnagin, K. (1999) Biochemistry 38, 13013-13025
58. Mizoue, L. S., Sullivan, S. K., King, D. S., Kledal, T. N., Schwartz, T. W., Bacon, K. B., and Handel, T. M. (2001) J. Biol. Chem. 276, 33906-33914
59. Ohnishi, Y., Senda, T., Nandhagopal, N., Sugimoto, K., Shioda, T., Nagal, Y., and Mitsui, Y. (2000) J. Interferon Cytokine Res. 20, 691-700
60. Lowman, H. B., Slagle, P. H., Deforge, L. E., Wirth, C. M., Gillece-Castro, B. L., Bourell, J. H., and Fairbrother, W. J. (1996) J. Biol. Chem. 271, 14344-14352
61. Williams, G., Borkakoti, N., Bottomley, G. A., Cowan, I., Fallowfield, A. G., Jones, P. S., Kirtland, S. J., Price, G. J., and Price, L. (1996) J. Biol. Chem. 271, 9579-9586
62. Clark-Lewis, I., Kim, K. S., Rajarathnam, K., Gong, J. H., Dewald, B., Moser, B., Baggiolini, M., and Sykes, B. D. (1995) J. Leukocyte Biol. 57, 703-711
63. Jarnagin, K., Grunberger, D., Mulkins, M., Wong, B., Hemmerich, S., Paavola, C., Bloom, A., Bhakta, S., Diehl, F., Freedman, R., McCarley, D., Polsky, I., Ping-Tsou, A., Kosaka, A., and Handel, T. M. (1999) Biochemistry 38, 16167-16177
64. Laurence, J. S., Blanpain, C., Burgner, J. W., Parmentier, M., and LiWang, P. J. (2000) Biochemistry 39, 3401-3409
65. Mayer, M. R., and Stone, M. J. (2001) J. Biol. Chem. 276, 13911-13916
66. Harrison, J. K., Fong, A. M., Swain, P. A., Chen, S., Yu, Y. R., Salafranca, M. N., Greenleaf, W. B., Imai, T., and Patel, D. D. (2001) J. Biol. Chem. 276, 21632-21641
67. Cole, A. M., Ganz, T., Liese, A. M., Burdick, M. D., Liu, L., and Strieter, R. M. (2001) J. Immunol. 167, 623-627
68. Koopmann, W., and Krangel, M. S. (1997) J. Biol. Chem. 272, 10103-10109
69. Wimley, W. C., Selsted, M. E., and White, S. H. (1994) Protein Sci. 3, 1362-1373
70. Yang, L., Weiss, T. M., Lehrer, R. I., and Huang, H. W. (2000) Biophys. J. 79, 2002-2009
71. Hill, C. P., Yee, J., Selsted, M. E., and Eisenberg, D. (1991) Science 251, 1481-1485
72. Miteva, M., Andersson, M., Karshikoff, A., and Otting, G. (1999) FEBS Lett. 462, 155-158
73. Shai, Y. (1999) Biochim. Biophys. Acta 1462, 55-70
74. Carson, M. (1991) J. Appl. Crystallogr. 24, 958-961