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Volumn 1, Issue , 2006, Pages 199-213

Genetic regulation of cardiogenesis and congenital heart disease

Author keywords

Cardiac development; Molecular biology; Signaling; Stem cells; Transcription factors

Indexed keywords

AORTA ARCH; CONGENITAL HEART DISEASE; CONGENITAL HEART MALFORMATION; GENE MUTATION; GENETIC REGULATION; HEART DEVELOPMENT; HEART VALVE; PRIORITY JOURNAL; REVIEW;

EID: 33645730373     PISSN: 15534006     EISSN: 15534014     Source Type: Book Series    
DOI: 10.1016/j.coi.2006.02.001     Document Type: Editorial
Times cited : (71)

References (83)
  • 1
    • 0034648772 scopus 로고    scopus 로고
    • A genetic blueprint for cardiac development
    • Srivastava D, Olson EN. 2000. A genetic blueprint for cardiac development. Nature 407:221-26
    • (2000) Nature , vol.407 , pp. 221-226
    • Srivastava, D.1    Olson, E.N.2
  • 2
    • 0037178779 scopus 로고    scopus 로고
    • Converging pathways and principles in heart development and disease: CV@CSH
    • Chien KR, Olson EN. 2002. Converging pathways and principles in heart development and disease: CV@CSH. Cell 110:153-62
    • (2002) Cell , vol.110 , pp. 153-162
    • Chien, K.R.1    Olson, E.N.2
  • 3
    • 0029583152 scopus 로고
    • Induction of avian cardiac myogenesis by anterior endoderm
    • Schultheiss TM, Xydas S, Lassar AB. 1995. Induction of avian cardiac myogenesis by anterior endoderm. Development 121:4203-4
    • (1995) Development , vol.121 , pp. 4203-4204
    • Schultheiss, T.M.1    Xydas, S.2    Lassar, A.B.3
  • 4
    • 0031018002 scopus 로고    scopus 로고
    • A role for bone morphogenetic proteins in the induction of cardiac myogenesis
    • Schultheiss TM, Burch JB, Lassar AB. 1997. A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev. 11:451-62
    • (1997) Genes Dev. , vol.11 , pp. 451-462
    • Schultheiss, T.M.1    Burch, J.B.2    Lassar, A.B.3
  • 5
    • 0035252543 scopus 로고    scopus 로고
    • Wnt antagonism initiates cardiogenesis in Xenopus laevis
    • Schneider VA, Mercola M. 2001. Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev. 15:304-15
    • (2001) Genes Dev. , vol.15 , pp. 304-315
    • Schneider, V.A.1    Mercola, M.2
  • 6
    • 0035252357 scopus 로고    scopus 로고
    • Inhibition of Wnt activity induces heart formation from posterior mesoderm
    • Marvin MJ, Di Rocco G, Gardiner A, Bush SM, Lassar AB. 2001. Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev. 15:316-27
    • (2001) Genes Dev. , vol.15 , pp. 316-327
    • Marvin, M.J.1    Di Rocco, G.2    Gardiner, A.3    Bush, S.M.4    Lassar, A.B.5
  • 7
    • 0013844231 scopus 로고
    • Development of pacemaker tissue in the embryonic heart
    • DeHaan RL. 1965. Development of pacemaker tissue in the embryonic heart. Ann. NY Acad. Sci. 127:7-18
    • (1965) Ann. NY Acad. Sci. , vol.127 , pp. 7-18
    • Dehaan, R.L.1
  • 8
    • 0027282774 scopus 로고
    • The gene tinman is required for specification of the heart and visceral muscles in Drosophila
    • Bodmer R. 1993. The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118:719-29
    • (1993) Development , vol.118 , pp. 719-729
    • Bodmer, R.1
  • 9
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
    • Lyons I, Parsons LM, Hartley L, Li R, Andrews JE, et al. 1995. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev. 9:1654-66
    • (1995) Genes Dev. , vol.9 , pp. 1654-1666
    • Lyons, I.1    Parsons, L.M.2    Hartley, L.3    Li, R.4    Andrews, J.E.5
  • 10
    • 0344428124 scopus 로고    scopus 로고
    • Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5
    • Tanaka M, Wechsler SB, Lee IW, Yamasaki N, Lawitts JA, et al. 1999. Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5. Development 126:1439-50
    • (1999) Development , vol.126 , pp. 1439-1450
    • Tanaka, M.1    Wechsler, S.B.2    Lee, I.W.3    Yamasaki, N.4    Lawitts, J.A.5
  • 11
    • 0031647381 scopus 로고    scopus 로고
    • Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
    • Fu Y, Yan W, Mohun TJ, Evans SM. 1998. Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner. Development 125:4439-49
    • (1998) Development , vol.125 , pp. 4439-4449
    • Fu, Y.1    Yan, W.2    Mohun, T.J.3    Evans, S.M.4
  • 12
    • 0032380010 scopus 로고    scopus 로고
    • Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 andXNkx2-5
    • Grow MW, Krieg PA. 1998. Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 andXNkx2-5. Dev. Biol. 204:187-96
    • (1998) Dev. Biol. , vol.204 , pp. 187-196
    • Grow, M.W.1    Krieg, P.A.2
  • 13
    • 0035967868 scopus 로고    scopus 로고
    • Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor
    • Wang D, Chang PS, Wang Z, Sutherland L, Richardson JA, et al. 2001. Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell 105:851-62
    • (2001) Cell , vol.105 , pp. 851-862
    • Wang, D.1    Chang, P.S.2    Wang, Z.3    Sutherland, L.4    Richardson, J.A.5
  • 14
    • 16844376805 scopus 로고    scopus 로고
    • Myocardin is sufficient and necessary for cardiac gene expression in Xenopus
    • Small EM, Warkman AS, Wang DZ, Sutherland LB, Olson EN, et al. 2005. Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. Development 132:987-97
    • (2005) Development , vol.132 , pp. 987-997
    • Small, E.M.1    Warkman, A.S.2    Wang, D.Z.3    Sutherland, L.B.4    Olson, E.N.5
  • 17
    • 0035461911 scopus 로고    scopus 로고
    • The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm
    • Kelly RG, Brown NA, Buckingham ME. 2001. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev. Cell 1:435-40
    • (2001) Dev. Cell , vol.1 , pp. 435-440
    • Kelly, R.G.1    Brown, N.A.2    Buckingham, M.E.3
  • 18
    • 0033598389 scopus 로고    scopus 로고
    • Congenital heart disease in mice deficient for the DiGeorge syndrome region
    • Lindsay EA, Botta A, Jurecic V, Carattini-Rivera S, Cheah YC, et al. 1999. Congenital heart disease in mice deficient for the DiGeorge syndrome region. Nature 401:379-83
    • (1999) Nature , vol.401 , pp. 379-383
    • Lindsay, E.A.1    Botta, A.2    Jurecic, V.3    Carattini-Rivera, S.4    Cheah, Y.C.5
  • 19
    • 0035263599 scopus 로고    scopus 로고
    • Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice
    • Lindsay EA, Vitelli F, Su H, Morishima M, Huynh T, et al. 2001. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 410:97-101
    • (2001) Nature , vol.410 , pp. 97-101
    • Lindsay, E.A.1    Vitelli, F.2    Su, H.3    Morishima, M.4    Huynh, T.5
  • 20
    • 17744395906 scopus 로고    scopus 로고
    • TBX1 is responsible for cardiovascular defects in velo-cardio-facial/ DiGeorge syndrome
    • Merscher S, Funke B, Epstein JA, Heyer J, Puech A, et al. 2001. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell 104:619-29
    • (2001) Cell , vol.104 , pp. 619-629
    • Merscher, S.1    Funke, B.2    Epstein, J.A.3    Heyer, J.4    Puech, A.5
  • 21
    • 0035098557 scopus 로고    scopus 로고
    • DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
    • Jerome LA, Papaioannou VE. 2001. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1. Nat. Genet. 27:286-91
    • (2001) Nat. Genet. , vol.27 , pp. 286-291
    • Jerome, L.A.1    Papaioannou, V.E.2
  • 22
    • 0037439240 scopus 로고    scopus 로고
    • Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer
    • Yamagishi H, Maeda J, Hu T, McAnally J, Conway SJ, et al. 2003. Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev. 17:269-81
    • (2003) Genes Dev. , vol.17 , pp. 269-281
    • Yamagishi, H.1    Maeda, J.2    Hu, T.3    McAnally, J.4    Conway, S.J.5
  • 23
    • 9444265974 scopus 로고    scopus 로고
    • Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors
    • Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, et al. 2004. Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development 131:5491-502
    • (2004) Development , vol.131 , pp. 5491-5502
    • Hu, T.1    Yamagishi, H.2    Maeda, J.3    McAnally, J.4    Yamagishi, C.5
  • 24
    • 4043094751 scopus 로고    scopus 로고
    • Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract
    • Xu H, Morishima M, Wylie JN, Schwartz RJ, Bruneau BG, et al. 2004. Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development 131:3217-27
    • (2004) Development , vol.131 , pp. 3217-3227
    • Xu, H.1    Morishima, M.2    Wylie, J.N.3    Schwartz, R.J.4    Bruneau, B.G.5
  • 25
    • 0346783332 scopus 로고    scopus 로고
    • Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart
    • Cai CL, Liang X, Shi Y, Chu PH, Pfaff SL, et al. 2003. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev. Cell 5:877-89
    • (2003) Dev. Cell , vol.5 , pp. 877-889
    • Cai, C.L.1    Liang, X.2    Shi, Y.3    Chu, P.H.4    Pfaff, S.L.5
  • 26
    • 13544272476 scopus 로고    scopus 로고
    • Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages
    • Laugwitz KL, Moretti A, Lam J, Gruber P, Chen Y, et al. 2005. Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 433:647-53
    • (2005) Nature , vol.433 , pp. 647-653
    • Laugwitz, K.L.1    Moretti, A.2    Lam, J.3    Gruber, P.4    Chen, Y.5
  • 27
    • 0038707943 scopus 로고    scopus 로고
    • Cardiac chamber formation: Development, genes, and evolution
    • Moorman AF, Christoffels VM. 2003. Cardiac chamber formation: Development, genes, and evolution. Physiol. Rev. 83:1223-67
    • (2003) Physiol. Rev. , vol.83 , pp. 1223-1267
    • Moorman, A.F.1    Christoffels, V.M.2
  • 28
    • 0031695316 scopus 로고    scopus 로고
    • A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme
    • Thomas T, Kurihara H, Yamagishi H, Kurihara Y, Yazaki Y, et al. 1998. A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. Development 125:3005-14
    • (1998) Development , vol.125 , pp. 3005-3014
    • Thomas, T.1    Kurihara, H.2    Yamagishi, H.3    Kurihara, Y.4    Yazaki, Y.5
  • 29
    • 0030926451 scopus 로고    scopus 로고
    • Homeodomain factor Nkx2-5 controls left/right asymmetric-expression of bHLH gene eHand during murine heart development
    • Biben C, Harvey RP. 1997. Homeodomain factor Nkx2-5 controls left/right asymmetric-expression of bHLH gene eHand during murine heart development. Genes Dev. 11:1357-69
    • (1997) Genes Dev. , vol.11 , pp. 1357-1369
    • Biben, C.1    Harvey, R.P.2
  • 30
    • 7444223591 scopus 로고    scopus 로고
    • Symmetry breaking and the evolution of development
    • Palmer AR. 2004. Symmetry breaking and the evolution of development. Science 306:828-33
    • (2004) Science , vol.306 , pp. 828-833
    • Palmer, A.R.1
  • 31
    • 0029089617 scopus 로고
    • A molecular pathway determining left-right asymmetry in chick embryogenesis
    • Levin M, Johnson RL, Stern CD, Kuehn M, Tabin C. 1995. A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82:803-14
    • (1995) Cell , vol.82 , pp. 803-814
    • Levin, M.1    Johnson, R.L.2    Stern, C.D.3    Kuehn, M.4    Tabin, C.5
  • 32
    • 0032493860 scopus 로고    scopus 로고
    • Pitx2 participates in the late phase of the pathway controlling left-right asymmetry
    • Piedra ME, Icardo JM, Albajar M, Rodriguez-Rey JC, Ros MA. 1998. Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Cell 94:319-24
    • (1998) Cell , vol.94 , pp. 319-324
    • Piedra, M.E.1    Icardo, J.M.2    Albajar, M.3    Rodriguez-Rey, J.C.4    Ros, M.A.5
  • 33
    • 18744369031 scopus 로고    scopus 로고
    • Identification of a Wnt/Dvl/beta-Catenin → Pitx2 pathway mediating cell-type-specific proliferation during development
    • Kioussi C, Briata P, Baek SH, Rose DW, Hamblet NS, et al. 2002. Identification of a Wnt/Dvl/beta-Catenin → Pitx2 pathway mediating cell-type-specific proliferation during development. Cell 111:673-85
    • (2002) Cell , vol.111 , pp. 673-685
    • Kioussi, C.1    Briata, P.2    Baek, S.H.3    Rose, D.W.4    Hamblet, N.S.5
  • 34
    • 0030656618 scopus 로고    scopus 로고
    • Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice
    • Supp DM, Witte DP, Potter SS, Brueckner M. 1997. Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature 389:963-66
    • (1997) Nature , vol.389 , pp. 963-966
    • Supp, D.M.1    Witte, D.P.2    Potter, S.S.3    Brueckner, M.4
  • 35
    • 0033377234 scopus 로고    scopus 로고
    • Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries
    • Supp DM, Brueckner M, Kuehn MR, Witte DP, Lowe LA, et al. 1999. Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries. Development 126:5495-504
    • (1999) Development , vol.126 , pp. 5495-5504
    • Supp, D.M.1    Brueckner, M.2    Kuehn, M.R.3    Witte, D.P.4    Lowe, L.A.5
  • 37
    • 0032952544 scopus 로고    scopus 로고
    • The homeobox gene Pitx2: Mediator of asymmetric left-right signaling in vertebrate heart and gut looping
    • Campione M, Steinbeisser H, Schweickert A, Deissler K, van Bebber F, et al. 1999. The homeobox gene Pitx2: Mediator of asymmetric left-right signaling in vertebrate heart and gut looping. Development 126:1225-34
    • (1999) Development , vol.126 , pp. 1225-1234
    • Campione, M.1    Steinbeisser, H.2    Schweickert, A.3    Deissler, K.4    Van Bebber, F.5
  • 38
    • 0033575364 scopus 로고    scopus 로고
    • Differences in left-right axis pathways in mouse and chick: Functions of FGF8 and SHH
    • Meyers EN, Martin GR. 1999. Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH. Science 285:403-6
    • (1999) Science , vol.285 , pp. 403-406
    • Meyers, E.N.1    Martin, G.R.2
  • 39
    • 0033575879 scopus 로고    scopus 로고
    • The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry
    • Rodriguez Esteban C, Capdevila J, Economides AN, Pascual J, Ortiz A, et al. 1999. The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry. Nature 401:243-51
    • (1999) Nature , vol.401 , pp. 243-251
    • Rodriguez Esteban, C.1    Capdevila, J.2    Economides, A.N.3    Pascual, J.4    Ortiz, A.5
  • 40
    • 0017162819 scopus 로고
    • A human syndrome caused by immotile cilia
    • Afzelius BA. 1976. A human syndrome caused by immotile cilia. Science 193:317-19
    • (1976) Science , vol.193 , pp. 317-319
    • Afzelius, B.A.1
  • 41
    • 0032428685 scopus 로고    scopus 로고
    • Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
    • Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, et al. 1998. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95:829-37
    • (1998) Cell , vol.95 , pp. 829-837
    • Nonaka, S.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4    Harada, A.5
  • 42
    • 0038784537 scopus 로고    scopus 로고
    • Two populations of node monocilia initiate left-right asymmetry in the mouse
    • McGrath J, Somlo S, Makova S, Tian X, Brueckner M. 2003. Two populations of node monocilia initiate left-right asymmetry in the mouse. Cell 114:61-73
    • (2003) Cell , vol.114 , pp. 61-73
    • McGrath, J.1    Somlo, S.2    Makova, S.3    Tian, X.4    Brueckner, M.5
  • 43
    • 0033212985 scopus 로고    scopus 로고
    • Abnormal nodal flow precedes situs inversus in iv and inv mice
    • Okada Y, Nonaka S, Tanaka Y, Saijoh Y, Hamada H, et al. 1999. Abnormal nodal flow precedes situs inversus in iv and inv mice. Mol. Cell 4:459-68
    • (1999) Mol. Cell , vol.4 , pp. 459-468
    • Okada, Y.1    Nonaka, S.2    Tanaka, Y.3    Saijoh, Y.4    Hamada, H.5
  • 44
    • 0033609103 scopus 로고    scopus 로고
    • Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II
    • Marszalek JR, Ruiz-Lozano P, Roberts E, Chien KR, Goldstein LS. 1999. Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc. Natl. Acad. Sci. USA 96:5043-48
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5043-5048
    • Marszalek, J.R.1    Ruiz-Lozano, P.2    Roberts, E.3    Chien, K.R.4    Goldstein, L.S.5
  • 46
    • 0029549692 scopus 로고
    • A subclass of bHLH proteins required for cardiac morphogenesis
    • Srivastava D, Cserjesi P, Olson EN. 1995. A subclass of bHLH proteins required for cardiac morphogenesis. Science 270:1995-99
    • (1995) Science , vol.270 , pp. 1995-1999
    • Srivastava, D.1    Cserjesi, P.2    Olson, E.N.3
  • 47
    • 0030903857 scopus 로고    scopus 로고
    • Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
    • Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN. 1997. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat. Genet. 16:154-60
    • (1997) Nat. Genet. , vol.16 , pp. 154-160
    • Srivastava, D.1    Thomas, T.2    Lin, Q.3    Kirby, M.L.4    Brown, D.5    Olson, E.N.6
  • 48
    • 0035891429 scopus 로고    scopus 로고
    • The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation
    • Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, et al. 2001. The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev. Biol. 239:190-203
    • (2001) Dev. Biol. , vol.239 , pp. 190-203
    • Yamagishi, H.1    Yamagishi, C.2    Nakagawa, O.3    Harvey, R.P.4    Olson, E.N.5
  • 49
    • 13444310919 scopus 로고    scopus 로고
    • The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner
    • McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, et al. 2005. The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development 132:189-201
    • (2005) Development , vol.132 , pp. 189-201
    • McFadden, D.G.1    Barbosa, A.C.2    Richardson, J.A.3    Schneider, M.D.4    Srivastava, D.5
  • 50
    • 0033947661 scopus 로고    scopus 로고
    • The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development
    • Yelon D, Ticho B, Halpern ME, Ruvinsky I, Ho RK, et al. 2000. The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development. Development 127:2573-82
    • (2000) Development , vol.127 , pp. 2573-2582
    • Yelon, D.1    Ticho, B.2    Halpern, M.E.3    Ruvinsky, I.4    Ho, R.K.5
  • 51
    • 0036578662 scopus 로고    scopus 로고
    • Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis
    • Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, et al. 2002. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat. Genet. 31:25-32
    • (2002) Nat. Genet. , vol.31 , pp. 25-32
    • Gottlieb, P.D.1    Pierce, S.A.2    Sims, R.J.3    Yamagishi, H.4    Weihe, E.K.5
  • 52
    • 21244464347 scopus 로고    scopus 로고
    • Bop, a regulator of right ventricular heart development, is a direct transcriptional activator of Mef2c in the developing heart
    • 51a. Phan D, Rasmussen TL, Nakagawa O, McAnally J, Gottlieb PD, et al. 2005. Bop, a regulator of right ventricular heart development, is a direct transcriptional activator of Mef2c in the developing heart. Development 132:2669-78
    • (2005) Development , vol.132 , pp. 2669-2678
    • Phan, D.1    Rasmussen, T.L.2    Nakagawa, O.3    McAnally, J.4    Gottlieb, P.D.5
  • 53
    • 0037775854 scopus 로고    scopus 로고
    • Neural crest and cardiovascular development: A 20-year perspective
    • Hutson MR, Kirby ML. 2003. Neural crest and cardiovascular development: A 20-year perspective. Birth Defects Res. C Embryo Today 69:2-13
    • (2003) Birth Defects Res. C Embryo Today , vol.69 , pp. 2-13
    • Hutson, M.R.1    Kirby, M.L.2
  • 54
    • 0036800025 scopus 로고    scopus 로고
    • Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse
    • Abu-Issa R, Smyth G, Smoak I, Yamamura K, Meyers EN. 2002. Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. Development 129:4613-25
    • (2002) Development , vol.129 , pp. 4613-4625
    • Abu-Issa, R.1    Smyth, G.2    Smoak, I.3    Yamamura, K.4    Meyers, E.N.5
  • 56
    • 0029142767 scopus 로고
    • Neural crest and cardiovascular patterning
    • Kirby ML, Waldo KL. 1995. Neural crest and cardiovascular patterning. Circ. Res. 77:211-15
    • (1995) Circ. Res. , vol.77 , pp. 211-215
    • Kirby, M.L.1    Waldo, K.L.2
  • 57
    • 0034022637 scopus 로고    scopus 로고
    • Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus
    • Satoda M, Zhao F, Diaz GA, Burn J, Goodship J, et al. 2000. Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus. Nat. Genet. 25:42-46
    • (2000) Nat. Genet. , vol.25 , pp. 42-46
    • Satoda, M.1    Zhao, F.2    Diaz, G.A.3    Burn, J.4    Goodship, J.5
  • 59
    • 0032510493 scopus 로고    scopus 로고
    • Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
    • de la Pompa JL, Timmerman LA, Takimoto H, Yoshida H, Elia AJ, et al. 1998. Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature 392:182-86
    • (1998) Nature , vol.392 , pp. 182-186
    • Pompa, J.L.1    Timmerman, L.A.2    Takimoto, H.3    Yoshida, H.4    Elia, A.J.5
  • 60
    • 0034091647 scopus 로고    scopus 로고
    • Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis
    • Chen B, Bronson RT, Klaman LD, Hampton TG, Wang JF, et al. 2000. Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis. Nat. Genet. 24:296-99
    • (2000) Nat. Genet. , vol.24 , pp. 296-299
    • Chen, B.1    Bronson, R.T.2    Klaman, L.D.3    Hampton, T.G.4    Wang, J.F.5
  • 61
    • 18344385476 scopus 로고    scopus 로고
    • Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
    • Tartaglia M, Mehler EL, Goldberg R, Zampino G, Brunner HG, et al. 2001. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat. Genet. 29:465-68
    • (2001) Nat. Genet. , vol.29 , pp. 465-468
    • Tartaglia, M.1    Mehler, E.L.2    Goldberg, R.3    Zampino, G.4    Brunner, H.G.5
  • 62
    • 17444453852 scopus 로고    scopus 로고
    • A role for Smad6 in development and homeostasis of the cardiovascular system
    • Galvin KM, Donovan MJ, Lynch CA, Meyer RI, Paul RJ, et al. 2000. A role for Smad6 in development and homeostasis of the cardiovascular system. Nat. Genet. 24:171-74
    • (2000) Nat. Genet. , vol.24 , pp. 171-174
    • Galvin, K.M.1    Donovan, M.J.2    Lynch, C.A.3    Meyer, R.I.4    Paul, R.J.5
  • 63
    • 3042680296 scopus 로고    scopus 로고
    • Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development
    • Cowan CA, Yokoyama N, Saxena A, Chumley MJ, Silvany RE, et al. 2004. Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev. Biol. 271:263-71
    • (2004) Dev. Biol. , vol.271 , pp. 263-271
    • Cowan, C.A.1    Yokoyama, N.2    Saxena, A.3    Chumley, M.J.4    Silvany, R.E.5
  • 64
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ. 1999. Notch signaling: Cell fate control and signal integration in development. Science 284:770-76
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 65
    • 9144246932 scopus 로고    scopus 로고
    • Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
    • Timmerman LA, Grego-Bessa J, Raya A, Bertran E, Perez-Pomares JM, et al. 2004. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 18:99-115
    • (2004) Genes Dev. , vol.18 , pp. 99-115
    • Timmerman, L.A.1    Grego-Bessa, J.2    Raya, A.3    Bertran, E.4    Perez-Pomares, J.M.5
  • 67
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. 1997. Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89:747-54
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 68
    • 0032715827 scopus 로고    scopus 로고
    • HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments
    • Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D. 1999. HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev. Biol. 216:72-84
    • (1999) Dev. Biol. , vol.216 , pp. 72-84
    • Nakagawa, O.1    Nakagawa, M.2    Richardson, J.A.3    Olson, E.N.4    Srivastava, D.5
  • 69
    • 0038875342 scopus 로고    scopus 로고
    • Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
    • Li L, Krantz ID, Deng Y, Genin A, Banta AB, et al. 1997. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat. Genet. 16:243-51
    • (1997) Nat. Genet. , vol.16 , pp. 243-251
    • Li, L.1    Krantz, I.D.2    Deng, Y.3    Genin, A.4    Banta, A.B.5
  • 70
    • 0030914459 scopus 로고    scopus 로고
    • Mutations in the human Jagged1 gene are responsible for Alagille syndrome
    • Oda T, Elkahloun AG, Pike BL, Okajima K, Krantz ID, et al. 1997. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat. Genet. 16:235-42
    • (1997) Nat. Genet. , vol.16 , pp. 235-242
    • Oda, T.1    Elkahloun, A.G.2    Pike, B.L.3    Okajima, K.4    Krantz, I.D.5
  • 71
    • 0033531963 scopus 로고    scopus 로고
    • Jagged1 mutations in patients ascertained with isolated congenital heart defects
    • Krantz ID, Smith R, Colliton RP, Tinkel H, Zackai EH, et al. 1999. Jagged1 mutations in patients ascertained with isolated congenital heart defects. Am. J. Med. Genet. 84:56-60
    • (1999) Am. J. Med. Genet. , vol.84 , pp. 56-60
    • Krantz, I.D.1    Smith, R.2    Colliton, R.P.3    Tinkel, H.4    Zackai, E.H.5
  • 72
    • 0032479573 scopus 로고    scopus 로고
    • Congenital heart disease caused by mutations in the transcription factor NKX2-5
    • Schott JJ, Benson DW, Basson CT, Pease W, Silberbach GM, et al. 1998. Congenital heart disease caused by mutations in the transcription factor NKX2-5. Science 281:108-11
    • (1998) Science , vol.281 , pp. 108-111
    • Schott, J.J.1    Benson, D.W.2    Basson, C.T.3    Pease, W.4    Silberbach, G.M.5
  • 73
    • 0033430230 scopus 로고    scopus 로고
    • Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways
    • Benson DW, Silberbach GM, Kavanaugh-McHugh A, Cottrill C, Zhang Y, et al. 1999. Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.J. Clin. Invest. 104:1567-73
    • (1999) J. Clin. Invest. , vol.104 , pp. 1567-1573
    • Benson, D.W.1    Silberbach, G.M.2    Kavanaugh-McHugh, A.3    Cottrill, C.4    Zhang, Y.5
  • 74
    • 11144357335 scopus 로고    scopus 로고
    • Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block
    • Pashmforoush M, Lu JT, Chen H, Amand TS, Kondo R, et al. 2004. Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell 117:373-86
    • (2004) Cell , vol.117 , pp. 373-386
    • Pashmforoush, M.1    Lu, J.T.2    Chen, H.3    Amand, T.S.4    Kondo, R.5
  • 75
    • 3042802511 scopus 로고    scopus 로고
    • Heart disease: An ongoing genetic battle?
    • Srivastava D. 2004. Heart disease: An ongoing genetic battle?Nature 429:819-22
    • (2004) Nature , vol.429 , pp. 819-822
    • Srivastava, D.1
  • 76
    • 0030636780 scopus 로고    scopus 로고
    • Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome
    • Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, et al. 1997. Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome. Nat. Genet. 15:30-35
    • (1997) Nat. Genet. , vol.15 , pp. 30-35
    • Basson, C.T.1    Bachinsky, D.R.2    Lin, R.C.3    Levi, T.4    Elkins, J.A.5
  • 77
    • 2442648749 scopus 로고    scopus 로고
    • TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed
    • Mori AD, Bruneau BG. 2004. TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed. Curr. Opin. Cardiol. 19:211-15
    • (2004) Curr. Opin. Cardiol. , vol.19 , pp. 211-215
    • Mori, A.D.1    Bruneau, B.G.2
  • 78
    • 0043267988 scopus 로고    scopus 로고
    • GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
    • Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, et al. 2003. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 424:443-47
    • (2003) Nature , vol.424 , pp. 443-447
    • Garg, V.1    Kathiriya, I.S.2    Barnes, R.3    Schluterman, M.K.4    King, I.N.5
  • 79
    • 0030996908 scopus 로고    scopus 로고
    • Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
    • Molkentin JD, Lin Q, Duncan SA, Olson EN. 1997. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 11:1061-72
    • (1997) Genes Dev. , vol.11 , pp. 1061-1072
    • Molkentin, J.D.1    Lin, Q.2    Duncan, S.A.3    Olson, E.N.4
  • 80
    • 0030916211 scopus 로고    scopus 로고
    • GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
    • Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, et al. 1997. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 11:1048-60
    • (1997) Genes Dev. , vol.11 , pp. 1048-1060
    • Kuo, C.T.1    Morrisey, E.E.2    Anandappa, R.3    Sigrist, K.4    Lu, M.M.5
  • 81
    • 0035152266 scopus 로고    scopus 로고
    • Multiple roles for Gata5 in zebrafish endoderm formation
    • Reiter JF, Kikuchi Y, Stainier DY. 2001. Multiple roles for Gata5 in zebrafish endoderm formation. Development 128:125-35
    • (2001) Development , vol.128 , pp. 125-135
    • Reiter, J.F.1    Kikuchi, Y.2    Stainier, D.Y.3
  • 82
    • 0035872950 scopus 로고    scopus 로고
    • Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis
    • Gajewski K, Zhang Q, Choi CY, Fossett N, Dang A, et al. 2001. Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis. Dev. Biol. 233:425-36
    • (2001) Dev. Biol. , vol.233 , pp. 425-436
    • Gajewski, K.1    Zhang, Q.2    Choi, C.Y.3    Fossett, N.4    Dang, A.5
  • 83
    • 0034444406 scopus 로고    scopus 로고
    • Left-right asymmetry and cardiac looping: Implications for cardiac development and congenital heart disease
    • Kathiriya IS, Srivastava D. 2000. Left-right asymmetry and cardiac looping: Implications for cardiac development and congenital heart disease. Am. J. Med. Genet. 97:271-79
    • (2000) Am. J. Med. Genet. , vol.97 , pp. 271-279
    • Kathiriya, I.S.1    Srivastava, D.2


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