메뉴 건너뛰기




Volumn 126, Issue 6, 1999, Pages 1225-1234

The homeobox gene Pitx2: Mediator of asymmetric left-right signaling in vertebrate heart and gut looping

Author keywords

Homeobox gene; Left right asymmetry; Mouse; Pitx2; Xenopus; Zebrafish

Indexed keywords

ANIMAL TISSUE; ARTICLE; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO PATTERN FORMATION; GENE EXPRESSION; GENE INDUCTION; HEART; HEART DEVELOPMENT; HOMEOBOX; INTESTINE; MESODERM; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; XENOPUS;

EID: 0032952544     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (317)

References (51)
  • 1
    • 0030926451 scopus 로고    scopus 로고
    • Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHAND during murine heart development
    • Biben, C. and Harvey, R. P. (1997). Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHAND during murine heart development. Genes Dev. 11, 1357-1169.
    • (1997) Genes Dev. , vol.11 , pp. 1357-11169
    • Biben, C.1    Harvey, R.P.2
  • 3
    • 0031950477 scopus 로고    scopus 로고
    • Development of the gut in Xenopus laevis
    • Chalmers, A. D. and Slack, J. M. W. (1998). Development of the gut in Xenopus laevis. Dev. Dyn. 212, 509-521.
    • (1998) Dev. Dyn. , vol.212 , pp. 509-521
    • Chalmers, A.D.1    Slack, J.M.W.2
  • 4
    • 0029955134 scopus 로고    scopus 로고
    • Overexpression of the tinman-related genes Xnkx2. 5 and Xnkx-2. 3 in Xenopus embryos results in myocardial hyperplasia
    • Cleaver, O. B., Patterson, K. D. and Krieg, P. A. (1996). Overexpression of the tinman-related genes Xnkx2. 5 and Xnkx-2. 3 in Xenopus embryos results in myocardial hyperplasia. Development 122, 3549-3556.
    • (1996) Development , vol.122 , pp. 3549-3556
    • Cleaver, O.B.1    Patterson, K.D.2    Krieg, P.A.3
  • 5
    • 0029993646 scopus 로고    scopus 로고
    • Relationship between asymmetric nodal expression and the direction of embryonic turning
    • Collignon, J., Varlet, I. and Robertson, E. J. (1996). Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 381, 155-158.
    • (1996) Nature , vol.381 , pp. 155-158
    • Collignon, J.1    Varlet, I.2    Robertson, E.J.3
  • 6
    • 0030578449 scopus 로고    scopus 로고
    • Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus
    • Danos, M. C. and Yost, H. J. (1996). Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus. Dev. Biol. 177, 96-103.
    • (1996) Dev. Biol. , vol.177 , pp. 96-103
    • Danos, M.C.1    Yost, H.J.2
  • 9
    • 0031906372 scopus 로고    scopus 로고
    • Pre-MBT patterning of early gene regulation in Xenopus: The role of the cortical rotation and mesoderm induction
    • Ding, X., Hausen, P. and Steinbeisser, H. (1998). Pre-MBT patterning of early gene regulation in Xenopus: the role of the cortical rotation and mesoderm induction. Mech Dev. 70, 15-24.
    • (1998) Mech Dev. , vol.70 , pp. 15-24
    • Ding, X.1    Hausen, P.2    Steinbeisser, H.3
  • 10
    • 0027996950 scopus 로고
    • Cardiac troponin I is a heart-specific marker in the Xenopus embryo: Expression during abnormal heart morphogenesis
    • Drysdale, T. A., Tonissen, K. E., Patterson K. D., Crawford M. J. and Krieg P. A. (1994). Cardiac troponin I is a heart-specific marker in the Xenopus embryo: expression during abnormal heart morphogenesis. Dev. Biol. 165, 432-441.
    • (1994) Dev. Biol. , vol.165 , pp. 432-441
    • Drysdale, T.A.1    Tonissen, K.E.2    Patterson, K.D.3    Crawford, M.J.4    Krieg, P.A.5
  • 11
    • 85027475782 scopus 로고
    • The early looping of the alimentary canal in the mammalian and human foetus and the mechanisms assumed to be active in this process
    • Enbom, G. (1939). The early looping of the alimentary canal in the mammalian and human foetus and the mechanisms assumed to be active in this process. Anat Rec 75, 409-414.
    • (1939) Anat Rec , vol.75 , pp. 409-414
    • Enbom, G.1
  • 12
    • 0031043428 scopus 로고    scopus 로고
    • Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation
    • Gage, P. J. and Camper S. A. (1997). Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation. Hum. Mol. Gen. 6, 457-464.
    • (1997) Hum. Mol. Gen. , vol.6 , pp. 457-464
    • Gage, P.J.1    Camper, S.A.2
  • 13
    • 0024320441 scopus 로고
    • DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9
    • Hanes, S. D. and Brent, R. (1989). DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell 57, 1275-1283.
    • (1989) Cell , vol.57 , pp. 1275-1283
    • Hanes, S.D.1    Brent, R.2
  • 14
    • 77957211015 scopus 로고
    • Visceral inversion and associated anomalies in the mouse
    • Hummel, K. P. and Chapman, D. B. (1959). Visceral inversion and associated anomalies in the mouse. J. Hered. 50, 9-13.
    • (1959) J. Hered. , vol.50 , pp. 9-13
    • Hummel, K.P.1    Chapman, D.B.2
  • 15
    • 0032478546 scopus 로고    scopus 로고
    • The left-right coordinator: The role of Vg1 in organizing left-right axis formation
    • Hyatt, B. A. and Yost, H. J. (1998). The left-right coordinator: the role of Vg1 in organizing left-right axis formation. Cell 93, 37-46.
    • (1998) Cell , vol.93 , pp. 37-46
    • Hyatt, B.A.1    Yost, H.J.2
  • 16
    • 0031051863 scopus 로고    scopus 로고
    • Control of vertebrate left-right asymmetry by a snail-related zinc finger gene
    • Isaac, A., Sargent, M. G. and Cooke, J. (1997). Control of vertebrate left-right asymmetry by a snail-related zinc finger gene. Science 275, 1301-1304.
    • (1997) Science , vol.275 , pp. 1301-1304
    • Isaac, A.1    Sargent, M.G.2    Cooke, J.3
  • 17
    • 0024374043 scopus 로고
    • Changes in the arrangment of actin bundles during heart looping in the chick embryo
    • Itasaki, N., Nakamura, H. and Yasuda, M. (1989). Changes in the arrangment of actin bundles during heart looping in the chick embryo. Anat. Embryol. 180, 413-420.
    • (1989) Anat. Embryol. , vol.180 , pp. 413-420
    • Itasaki, N.1    Nakamura, H.2    Yasuda, M.3
  • 18
    • 0026026793 scopus 로고
    • Actin bundles on the right side in the caudal part of the heart tube play a role in dextro-looping in the embryonic chick heart
    • Itasaki, N., Nakamura, H., Sumida, H. and Yasuda, M. (1991). Actin bundles on the right side in the caudal part of the heart tube play a role in dextro-looping in the embryonic chick heart. Anat. Embryol. 183, 29-39.
    • (1991) Anat. Embryol. , vol.183 , pp. 29-39
    • Itasaki, N.1    Nakamura, H.2    Sumida, H.3    Yasuda, M.4
  • 19
    • 0028787260 scopus 로고
    • Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation
    • Jones, C. M., Kuehn, M. R., Hogan, B. L. M., Smith, J. C. and Wright, C. V. E. (1995). Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121, 3651-3662.
    • (1995) Development , vol.121 , pp. 3651-3662
    • Jones, C.M.1    Kuehn, M.R.2    Hogan, B.L.M.3    Smith, J.C.4    Wright, C.V.E.5
  • 21
    • 0031127303 scopus 로고    scopus 로고
    • Embryonic asymmetry: Left TGFB at the right time?
    • King, T. and Brown, N. A. (1997). Embryonic asymmetry: left TGFB at the right time? Curr. Biol. 7, 212-215.
    • (1997) Curr. Biol. , vol.7 , pp. 212-215
    • King, T.1    Brown, N.A.2
  • 22
    • 0030776222 scopus 로고    scopus 로고
    • Expression pattern of Brx1 (Rieg gene). Sonic hedgehog, Nk2. 2, Dlx1 and Arx during zona limithans intrathalamica and embryonic ventral lateral geniculate nuclear formation
    • Kitamura, K., Miura, H., Yanazawa, M., Miyashita, T. and Kato, K. (1997). Expression pattern of Brx1 (Rieg gene). Sonic hedgehog, Nk2. 2, Dlx1 and Arx during zona limithans intrathalamica and embryonic ventral lateral geniculate nuclear formation. Mech. Dev. 67, 83-96.
    • (1997) Mech. Dev. , vol.67 , pp. 83-96
    • Kitamura, K.1    Miura, H.2    Yanazawa, M.3    Miyashita, T.4    Kato, K.5
  • 24
    • 0029939460 scopus 로고    scopus 로고
    • Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene
    • Lamonerie, T., Tremblay, J. J., Lanctot, C., Therrien, M., Gauthire, Y. and Drouin, J. (1996). Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene. Genes Dev. 10, 1284-1295.
    • (1996) Genes Dev. , vol.10 , pp. 1284-1295
    • Lamonerie, T.1    Tremblay, J.J.2    Lanctot, C.3    Therrien, M.4    Gauthire, Y.5    Drouin, J.6
  • 25
    • 0030907502 scopus 로고    scopus 로고
    • Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development
    • Lohr, J. L., Danos, M. C. and Yost, H. J. (1997). Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development. Development 124, 1465-1472.
    • (1997) Development , vol.124 , pp. 1465-1472
    • Lohr, J.L.1    Danos, M.C.2    Yost, H.J.3
  • 26
    • 0032493897 scopus 로고    scopus 로고
    • The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetricc signals
    • Logan, M., Pagan-Westphal, S. M., Smith, D. M., Paganessi, L. and Tabin, C. J. (1998). The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetricc signals. Cell 94, 307-317.
    • (1998) Cell , vol.94 , pp. 307-317
    • Logan, M.1    Pagan-Westphal, S.M.2    Smith, D.M.3    Paganessi, L.4    Tabin, C.J.5
  • 27
    • 0029089617 scopus 로고
    • A molecular pathway determining left-right asymmetry in chick embryogenesis
    • Levin, M., Johnson, R., Stern, C., Kuehn, M. and Tabin, C. (1995). A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82, 803-814.
    • (1995) Cell , vol.82 , pp. 803-814
    • Levin, M.1    Johnson, R.2    Stern, C.3    Kuehn, M.4    Tabin, C.5
  • 28
    • 0031238780 scopus 로고    scopus 로고
    • Left/right patterning signals and the independent regulation ot different aspects of situs in the chick embryo
    • Levin, M., Pagan, S., Roberts, D. J., Cooke, J., Kuehn, M. R. and Tabin, C. J. (1997). Left/right patterning signals and the independent regulation ot different aspects of situs in the chick embryo. Dev. Biol. 189, 57-67.
    • (1997) Dev. Biol. , vol.189 , pp. 57-67
    • Levin, M.1    Pagan, S.2    Roberts, D.J.3    Cooke, J.4    Kuehn, M.R.5    Tabin, C.J.6
  • 30
    • 0029932564 scopus 로고    scopus 로고
    • Left-right asymmetric expression of the TGFβ-family member lefty in mouse embryos
    • Meno, C., Saijoh, Y., Fujii, H., Ikeda, M., Yokoyama, T., Yokoyama, M., Toyoda, Y, and Hamada, H. (1996). Left-right asymmetric expression of the TGFβ-family member lefty in mouse embryos. Nature 381, 151-155.
    • (1996) Nature , vol.381 , pp. 151-155
    • Meno, C.1    Saijoh, Y.2    Fujii, H.3    Ikeda, M.4    Yokoyama, T.5    Yokoyama, M.6    Toyoda, Y.7    Hamada, H.8
  • 33
    • 0030266375 scopus 로고    scopus 로고
    • Otlx2, an otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain
    • Mucchielli, M-I., Martinez, Salvador, Pattyn, A., Godiris, C. and Brunet, J-F. (1996). Otlx2, an otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain. Mol. Cell. Neurosc. 8, 252-271.
    • (1996) Mol. Cell. Neurosc. , vol.8 , pp. 252-271
    • Mucchielli, M.-I.1    Martinez2    Salvador3    Pattyn, A.4    Godiris, C.5    Brunet, J.-F.6
  • 34
    • 0031239279 scopus 로고    scopus 로고
    • Organizer induction determines left-right asymmetry in Xenopus
    • Nascone, N. and Mercola, M. (1997). Organizer induction determines left-right asymmetry in Xenopus. Dev. Biol. 189, 68-78.
    • (1997) Dev. Biol. , vol.189 , pp. 68-78
    • Nascone, N.1    Mercola, M.2
  • 36
    • 0032478497 scopus 로고    scopus 로고
    • The transfer of left-right positional information during chick embryogenesis
    • Pagan-Westphal, S. M., and Tabin, C. J. (1998). The transfer of left-right positional information during chick embryogenesis. Cell 93, 25-35.
    • (1998) Cell , vol.93 , pp. 25-35
    • Pagan-Westphal, S.M.1    Tabin, C.J.2
  • 37
    • 0032493860 scopus 로고    scopus 로고
    • Pitx2 participates in the late phase of the pathway controlling left-right asymmetry
    • Piedra, M. K., Icaardo, J. M., Albajar, M., Rodriguez-Rey, J. C. and Ros, M. A. (1998). Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Cell 94, 319-324.
    • (1998) Cell , vol.94 , pp. 319-324
    • Piedra, M.K.1    Icaardo, J.M.2    Albajar, M.3    Rodriguez-Rey, J.C.4    Ros, M.A.5
  • 38
  • 39
    • 0028352113 scopus 로고
    • Xenopus embryos regulate the nuclear organization of XMyoD
    • Rupp, R A. W., Snider, L. and Weintraub, H. (1994). Xenopus embryos regulate the nuclear organization of XMyoD. Genes Dev. 8, 1311-1323.
    • (1994) Genes Dev. , vol.8 , pp. 1311-1323
    • Rupp, R.A.W.1    Snider, L.2    Weintraub, H.3
  • 42
    • 0030869668 scopus 로고    scopus 로고
    • Functional differences among Xenopus nodal-related genes in left-right axis determination
    • Sampath, K., Cheng, A. M. S., Krisch, A. and Wright, C. V. E. (1997). Functional differences among Xenopus nodal-related genes in left-right axis determination. Development 124, 3293-3302.
    • (1997) Development , vol.124 , pp. 3293-3302
    • Sampath, K.1    Cheng, A.M.S.2    Krisch, A.3    Wright, C.V.E.4
  • 43
    • 0024355482 scopus 로고
    • Desmin and titin expression in early postimplantation mouse embryos
    • Schaart, G., Viehahn, C., Langmann, W. and Ramaekers, F. C. S. (1989). Desmin and titin expression in early postimplantation mouse embryos. Development 107, 585-596.
    • (1989) Development , vol.107 , pp. 585-596
    • Schaart, G.1    Viehahn, C.2    Langmann, W.3    Ramaekers, F.C.S.4
  • 45
    • 0032007716 scopus 로고    scopus 로고
    • Xenopus eHAND: A marker for the developing cardiovascular system of the embryo is regulated by bone morphogenetic proteins
    • Sparrow, D. B., Kotecha, S., Towers, N. and Mohun, T. J. (1998). Xenopus eHAND: a marker for the developing cardiovascular system of the embryo is regulated by bone morphogenetic proteins. Mech Dev. 71, 151-163.
    • (1998) Mech Dev. , vol.71 , pp. 151-163
    • Sparrow, D.B.1    Kotecha, S.2    Towers, N.3    Mohun, T.J.4
  • 46
    • 0029549692 scopus 로고
    • A subclass of bHLH proteins required for cardiac morphogenesis
    • Srivastava, D., Cserjesi, P. and Olson, E. N. (1995). A subclass of bHLH proteins required for cardiac morphogenesis. Science 270, 1995-1999.
    • (1995) Science , vol.270 , pp. 1995-1999
    • Srivastava, D.1    Cserjesi, P.2    Olson, E.N.3
  • 47
    • 0014466778 scopus 로고
    • The origin of heart asymmetry: Right and left contributions to the early chick embryo heart
    • Stalsberg, H. (1969). The origin of heart asymmetry: Right and left contributions to the early chick embryo heart. Dev. Biol. 19, 109-129.
    • (1969) Dev. Biol. , vol.19 , pp. 109-129
    • Stalsberg, H.1
  • 48
    • 0030022980 scopus 로고    scopus 로고
    • Left-right asymmetric location of flectin in the extracellular matrix during heart looping
    • Tsuda, T., Philp, N., Zile, J. K. and Linask, K. K. (1996). Left-right asymmetric location of flectin in the extracellular matrix during heart looping. Dev. Biol. 173, 39-50.
    • (1996) Dev. Biol. , vol.173 , pp. 39-50
    • Tsuda, T.1    Philp, N.2    Zile, J.K.3    Linask, K.K.4
  • 50
    • 51249193242 scopus 로고
    • Experimentelle Untersuchungen über Situs inversus viscerum
    • Wilhelmi, H. (1921). Experimentelle Untersuchungen über Situs inversus viscerum. Arch. EntwMech. Org. 48, 517-532.
    • (1921) Arch. EntwMech. Org. , vol.48 , pp. 517-532
    • Wilhelmi, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.