An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome

Development

Volumn 129, Issue 19, 2002, Pages 4591-4603

  Frank, Deborah U ^a   Fotheringham, Lori K ^a   Brewer, Judson A ^a   Muglia, Louis J ^a   Tristani Firouzi, Martin ^a   Capecchi, Mario R ^a   Moon, Anne M ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

22q11 deletion syndromes; Congenital heart disease; Endoderm; FGF8; Immunodeficiency; Interrupted aortic arch; Outflow tract; Pharyngeal arch artery; Pharyngeal arches; Truncus arteriosus

Indexed keywords

FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 8;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOVASCULAR MALFORMATION; CHROMOSOME 22Q; CHROMOSOME DELETION; CONGENITAL BLOOD VESSEL MALFORMATION; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; EMBRYO; GENE DISRUPTION; GENETIC VARIABILITY; GREAT BLOOD VESSEL; LETHALITY; MESENCHYME; MOUSE; MOUSE MUTANT; NEURAL CREST; NONHUMAN; PHARYNX; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIVITY ANALYSIS;

ABNORMALITIES, MULTIPLE; ALLELES; ANIMALS; APOPTOSIS; BRANCHIAL REGION; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 22; FEMALE; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; HEART DEFECTS, CONGENITAL; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; NEURAL CREST; PARATHYROID GLANDS; RNA, MESSENGER; SYNDROME; T-LYMPHOCYTES; THYMUS GLAND;

ANIMALIA;

EID: 0036800398     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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