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Organic and Biomolecular Chemistry

Volumn 4, Issue 2, 2006, Pages 206-210

Molecular mechanisms of antibiotic resistance: QM/MM modelling of deacylation in a class A β-lactamase

(4) Hermann, Johannes C a,b Ridder, Lars a,c Höltje, Hans Dieter d Mulholland, Adrian J a

a UNIVERSITY OF BRISTOL (United Kingdom)

b UNIVERSITY OF CALIFORNIA (United States)

c NV ORGANON (Netherlands)

d HEINRICH HEINE UNIVERSITY (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

Β-LACTAMASE INHIBITORS; DEACYLATION; MOLECULAR MECHANICS;

ALKYLATION; ANTIBIOTICS; ENZYME INHIBITION; QUANTUM THEORY; REACTION KINETICS;

ENZYMES;

ANTIINFECTIVE AGENT; BETA LACTAMASE; ESCHERICHIA COLI PROTEIN; PENICILLIN G; WATER;

ACYLATION; ANTIBIOTIC RESISTANCE; ARTICLE; CHEMICAL MODEL; CHEMISTRY; METABOLISM; QUANTUM THEORY;

ACYLATION; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI PROTEINS; MODELS, CHEMICAL; PENICILLIN G; QUANTUM THEORY; WATER;

ESCHERICHIA COLI;

EID: 33645699595 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/b512969a Document Type: Article

Times cited : (66)

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