pK(a) calculations for class A β-lactamases: Methodological and mechanistic implications

Biophysical Journal

Volumn 73, Issue 5, 1997, Pages 2416-2426

  Raquet, X ^b,c   Lounnas, V ^b   Lamotte Brasseur, J ^a   Frere J M ^a   Wade, R C ^b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c Max Delbruck Laboratorium der Max Planck Gesellschaft   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM DERIVATIVE; BETA LACTAMASE; GLUTAMINE; LYSINE; PENICILLIN DERIVATIVE; BETA LACTAMASE TEM 1; BETA-LACTAMASE TEM-1; PROTON;

ACYLATION; ARTICLE; BACILLUS LICHENIFORMIS; CONTROLLED STUDY; DIELECTRIC CONSTANT; NONHUMAN; PH; PKA; PROTEIN STRUCTURE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER PROGRAM; COMPUTER SIMULATION; ELECTRICITY; HYDROGEN BOND; METABOLISM; TITRIMETRY;

ACYLATION; BETA-LACTAMASES; BINDING SITES; CATALYSIS; COMPUTER SIMULATION; ELECTROSTATICS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; PROTONS; SOFTWARE; TITRIMETRY;

EID: 0030609096     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(97)78270-5     Document Type: Article

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