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Journal of the American Chemical Society

Volumn 124, Issue 8, 2002, Pages 1809-1816

Role of protein flexibility in enzymatic catalysis: Quantum mechanical-molecular mechanical study of the deacylation reaction in class a β-lactamases

(3) Castillo, Raquel a Silla, Estanislao b Tuñón, Iñaki b

a UNIVERSITAT JAUME I (Spain)

b UNIVERSITY OF VALENCIA (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN FLEXIBILITY;

ACYLATION; ANTIBIOTICS; COMPLEXATION; CRYSTALLOGRAPHY; ENZYME INHIBITION; HYDROLYSIS; PROTEINS; QUANTUM THEORY;

CATALYSIS;

ANTIBIOTIC AGENT; BETA LACTAM; BETA LACTAMASE; CARBOXYLIC ACID; PENICILLIN DERIVATIVE; SERINE;

ARTICLE; CRYSTALLOGRAPHY; DEACETYLATION; ENZYME MECHANISM; GEOMETRY; MATHEMATICAL COMPUTING; PROTON TRANSPORT; QUANTUM MECHANICS;

ACYLATION; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; BETA-LACTAMS; CATALYSIS; HYDROLYSIS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; QUANTUM THEORY; THERMODYNAMICS;

EID: 0037181086 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja017156z Document Type: Article

Times cited : (31)

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