Preoperative chemoradiation in the management of adenocarcinoma of the body of the pancreas

American Surgeon

Volumn 68, Issue 4, 2002, Pages 330-335

  Arnoletti, Juan P ^a   Hoffman, John P ^a   Ross, Eric A ^a   Kagan, Steven A ^a   Meropol, Neal J ^a   Freedman, Gary ^a   Eisenberg, Burton ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; GEMCITABINE; MITOMYCIN C;

ADJUVANT THERAPY; ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CELIAC ARTERY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HEPATIC ARTERY; HUMAN; MALE; METASTASIS; MULTIPLE CYCLE TREATMENT; PANCREAS ADENOCARCINOMA; PANCREAS RESECTION; PORTAL VEIN; POSTOPERATIVE CARE; PREOPERATIVE CARE; SEPSIS; SUPERIOR MESENTERIC ARTERY; TREATMENT OUTCOME; TUMOR GROWTH; TUMOR VOLUME; VASCULAR SURGERY; ADENOCARCINOMA; ADJUVANT CHEMOTHERAPY; MIDDLE AGED; MORTALITY; PANCREAS TUMOR; PROGNOSIS; RETROSPECTIVE STUDY; SURVIVAL;

ADENOCARCINOMA; AGED; CHEMOTHERAPY, ADJUVANT; FEMALE; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PREOPERATIVE CARE; PROGNOSIS; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 0036549518     PISSN: 00031348     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Johnson CD, Schwall G, Flechtenmacher J, Trede M. Resection for adenocarcinoma of the body and tail of the pancreas. Br J Surg 1993;80:1177-9.
2. Nordback IH, Hruban RH, Boitnott JK, et al. Carcinoma of the body and tail of the pancreas. Am J Surg 1992;164:26-31.
3. Dalton RR, Sarr MG, van Heerden JA, Colby TV. Carcinoma of the body and tail of the pancreas: Is curative resection justified? Surgery 1992;111:489-94.
4. Brennan MF, Moccia RD, Klimstra D. Management of adenocarcinoma of the body and tail of the pancreas. Ann Surg 1996;223:506-12.
5. Conlon KC, Klimstra DS, Brennan MF. Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Ann Surg 1996;223:273-9.
6. Hoffman JP, Lipsitz S, Pisansky T, et al. Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: An Eastern Cooperative Oncology Group Study. J Clin Oncol 1998;16:317-23.
7. Hoffman JP, Weese JL, Solin LJ, et al. A single institutional experience with preoperative chemoradiotherapy for stage I-III pancreatic adenocarcinoma. Am Surg 1993;59:772-80.
8. Hoffman JP, McGinn CJ, Szarka C, et al. A phase I study of preoperative gemcitabine (GEM) with radiation therapy (RT) followed by postoperative GEM for patients with localized, resectable pancreatic adenocarcinoma (PAC) (Abstr). Proc Am Soc Clin Oncol 1998;17:A1090.
9. Miller AR, Robinson HK, Lee JE, et al. Neoadjuvant chemoradiation for adenocarcinoma of the pancreas. Surg Oncol Clin North Am 1998;7:183-97.
10. Fleming ID, Cooper JS, Henson Dh, et al., eds. AJCC Cancer Staging Manual. 5th Ed. Philadelphia: Lippincott-Raven. 1997. p 122.
11. Appleby LH. The coeliac axis in the expansion of the operation for gastric carcinoma. Cancer 1953;6:704-7.
12. Sener SF, Fremgen A, Menck HR, Winchester DP. Pancreatic cancer: A report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database. J Am Coll Surg 1999;189:1-7.
13. Sperti C, Pasquali C, Pedrazzoli S. Ductal adenocarcinoma of the body and tail of the pancreas. J Am Coll Surg 1997;185:255-9.
14. Harrison LE, Klimstra DS, Brennan MF. Isolated portal vein involvement in pancreatic adenocarcinoma: A contraindication for resection? Ann Surg 1996;224:342-7.
15. Leach SD, Lee JE, Charnsangavej C, et al. Survival following pancreaticoduodenectomy with resection of the superior mesenteric-portal vein confluence for adenocarcinoma of the pancreatic head. Br J Surg 1998;85:611-7.
16. Takahashi S, Ogata Y, Tsuzuki T. Combined resection of the pancreas and portal vein for pancreatic cancer. Br J Surg 1994;81:1190-3.
17. Klempnauer J, Ridder GJ, Bektas H, Pichlmayr R. Extended resections of ductal pancreatic cancer: Impact on operative risk and prognosis. Oncology 1996;53:47-53.
18. Sasson A, Hoffman JP, Ross EA, et al. En bloc resection for locally advanced cancer of the pancreas. Abstract. Proceedings of the Society for Surgery of the Alimentary Tract, 2001.
19. White R, Lee C, Anscher M, et al. Preoperative chemoradiation for patients with locally advanced adenocarcinoma of the pancreas. Ann Surg Oncol 1999;6:38-45.
20. Pingpank JF, Hoffman JP, Ross EA, et al. Effect of preoperative chemoradiotherapy on surgical margin status of resected adenocarcinoma of the head of the pancreas. J Gastrointest Surg 2001;5:121-30.
21. Sohn TA, Yeo CJ, Cameron JL, et al. Resected adenocarcinoma of the pancreas-616 patients: Results, outcomes, and prognostic indicators. J Gastrointest Surg 2000;4:567-79.