Uterine restoration by radiation sequelae regression with combined pentoxifylline-tocopherol: A phase II study

Fertility and Sterility

Volumn 77, Issue 6, 2002, Pages 1219-1226

  Letur Könirsch, Hélène ^a   Guis, F ^b   Delanian, Sylvie ^c  

^a INSTITUT MUTUALISTE MONTSOURIS   (France)

^b Rue de Rennes   (France)

^c SAINT LOUIS HOSPITAL   (France)

Author keywords

Endometrium; Pentoxifylline; Radiation induced fibrosis; Tocopherol; Uterine artery blood flow

Indexed keywords

ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; ESTRADIOL; PENTOXIFYLLINE; PROGESTERONE;

ADULT; AMENORRHEA; ARTICLE; CANCER RADIOTHERAPY; CHILDHOOD CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ECHOGRAPHY; EMBRYO TRANSFER; ENDOMETRIUM; FEMALE; HORMONE SUBSTITUTION; HUMAN; MENSTRUAL CYCLE; MULTIMODALITY CANCER THERAPY; ORGAN SIZE; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PUBLIC HOSPITAL; RADIATION DOSE; UTERUS; UTERUS BLOOD FLOW; UTERUS DISEASE;

ADULT; ANTIOXIDANTS; ARTERIES; DRUG THERAPY, COMBINATION; ESTRADIOL; FEMALE; HUMANS; PENTOXIFYLLINE; PULSE; RADIATION INJURIES; RADIATION-PROTECTIVE AGENTS; RADIOTHERAPY; REGIONAL BLOOD FLOW; TOCOPHEROLS; UTERINE DISEASES; UTERUS;

EID: 0036286713     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(02)03120-5     Document Type: Article

References (35)

1. Radiation-induced premature menopause: A misconception
2. Cancer and oocyte donation
3. Reproductive technologies 1998: Options available for the cancer patient
4. Factors of importance for implantation and problems after treatment for childhood cancer
5. Application carcinologique du don d'ovocyte
6. Effect of radiation on the human reproductive system
7. Abdominal irradiation in childhood: The potential for pregnancy
8. Pregnancy outcomes in childhood cancer survivors: Probable effects of abdominal irradiation
9. Outcome of pregnancy in survivors of Wilms tumors
10. Female reproductive organs
11. Endometrial thickness: A predictor of implantation in ovum recipients?
12. Iatrogenic fibrosis in oncology (part I): Description and pathophysiological aspects
13. Iatrogenic fibrosis in oncology (part II): Etiologic conditions and possible therapeutic attitude
14. Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: Clinical trial
15. Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: An experimental study
16. Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol
17. Striking regression of subcutaneous fibrosis induced by high-doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: An experimental study
18. Ultrasound imaging 2000: Assessment of utero-ovarian blood flow with transvaginal color doppler sonography: Potential clinical applications in infertility
19. Complete endometrium healing by reversion of radiation-induced abrasion after combined pentoxifylline-tocopherol treatment
20. Ovarian failure following abdominal irradiation in childhood: The radiosensitivity of the human oocyte
21. Non homogeneous hyperechogenic pattern 3 days after embryo transfer is associated with lower pregnancy rates
22. Ultrasonic evaluation of endometrial growth in women with normal cycles during spontaneous and stimulated cycles
23. Relationship of the individual uterine size and the endometrial thickness in stimulated cycles
24. 2 administration: Effects on endometrial thickness, uterine perfusion, and contractility
25. Vaginal sildenafil (Viagra): A preliminary report of a novel method to improve uterine artery blood flow and endometrial development in patients undergoing IVF
26. Stromal-epithelial interactions modulate estrogen responsiveness in normal human endometrium
27. Ovarian and uterine characteristics after total body irradiation in childhood and adolescence: Response to sex steroid replacement
28. IL10 prevents naturally occurring fetal loss in the CBA×DBA/2 mating combination, and local defect in IL10 production in this abortion-prone combination is corrected by in vivo injection of IFN-g
29. Low levels of reactive oxygen species as modulators of cell function
30. Effect of in vivo heart irradiation on the development of antioxidant defenses and cardiac functions in the rat
31. Abnormal phenotype of human cultured fibroblasts from cutaneous fibrosis induced by therapeutic irradiation
32. Antioxidant therapy partially blocks immune-induced lung fibrosis
33. Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver
34. Oxidative stress, vitamin E and progestin breakthrough bleeding
35. Changes in activity of superoxide dismutase in the human endometrium throughout the menstrual cycle and in early pregnancy