Phytochemicals in the vaccinium family: Bilberries, blueberries, and cranberries

Phytochemicals in Nutrition and Health

Volumn , Issue , 2002, Pages 19-40

  Camire, Mary Ellen ^a  

^a UNIVERSITY OF MAINE   (United States)

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EID: 33645336639     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (84)

1. Alfieri, R., and Sole, P. 1966. Influence des anthocyanosides administrés par voie oro-perlin-guale sur l’adapto-électrorétinogramme (AERG) en lumiére rouge chez l’ Homme, Comptes Rendus des Séances de la Société de Biologie et des Ses Filiales, 160(8):1590-1593.
2. Amouretti, M. 1972. Intérêt thérapeutique des anthocyanosides de Vaccinium myrtillus dans un service de médecine interne, Thérapeutique, 48(9):579–581.
3. Andriambeloson, E., Magnier, C., Haan-Archipoff, G., Lobstein, A., Anton, R., Beretz, A., Stoclet, J.C., and Andriantsitohaina, R. 1998. Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta, J. Nutr., 128(12):2324–2333.
4. Andriambeloson, E., Stoclet, J.C., and Andriantsitohaina, R. 1996. Effets vasculaires d’ex-traits végétaux contenant des dérivés polyphénoliques, in Polyphenols Communications 96, J. Vercauteren, C. Chèze, M.C. Dumon, and J.F. Weber, 2:421–422. Groupe Polyphénols, Bordeaux, France.
5. Avorn, J., Monane, M., Gurwitz, J.H., Glynn, R.J., Choodnovskiy, I., and Lipsitz, L.A., 1994. Reduction of bacteriuria and pyuria after ingestion of cranberry juice, JAMA, 271(10):751-754.
6. Bertuglia, S., Malandrino, S., and Colantuoni, A. 1995. Effect of Vaccinium myrtillus anthocyanosides on ischaemia reperfusion injury in hamster cheek pouch microcirculation, Pharmacol. Res., 31(3/4):183–187.
7. Bettini, V., Fiori, A., Martino, R., Mayellaro, R., and Ton, P. 1985. Study of the mechanism whereby anthocyanosides potentiate the effect of catecholamines on coronary vessels, Fitoterapia, 56(2):67–72.
8. Bettini, V., Martino, R., Tegazzin, V., and Ton, P. 1987. Risposte contrattili di segmenti di arterie coronarie all’istamina e all’angiotensina II in presenza di antocianosidi del mir-tillo, Cardiologia, 32(10):1155–1159.
9. Boger, R.H., Lentz, S.R., Bode-Boger, S.M., Knapp, H.R., and Haynes, W.G. 2001. Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans, Clin. Sci., (Colch), 100(2):161–167.
10. Bomser, J., Madhavi, D.L., Singletary, K., and Smith, M.A.L. 1996. In vitro anticancer activity of fruit extracts from Vaccinium species, Planta Med., 62(3):212–216.
11. Boniface, R., Miskulin, M., Robert, L., and Robert, A.M. 1986. Pharmacological properties of Myrtillus anthocyanosides: correlation with results of treatment of diabetic microan-giopathy, in Flavonoids and Bioflavonoids, 1985, L. Farkas, M. Gabor, and F. Kallay, eds., Amsterdam: Elsevier, pp. 293–301.
12. Burger, O., Ofek, I., Tabak, M., Weiss, E.I., Sharon, N., and Neeman, I. 2000. A high molecular mass constituent of cranberry juice inhibits helicobacter pylori adhesion to human gastric mucus, FEMS Immunol. Med. Microbiol., 29(4):295–301.
13. Cao, G., Muccitelli, H.U., Sánchez-Moreno, C., and Prior, R.L. 2001. Anthocyanins are absorbed in glycated forms in elderly women: a pharmacokinetic study, Am. J. Clin. Nutr., 73(4):920–926.
14. Cao, G., Martin, A., Sofic, E., McEwen, J., O’Brien, C., Lischner, N., Ehlenfeldt, M., Kalt, W., Krewer, G., and Mainland, C.M. 1998. Antioxidant capacity as influenced by total phenolic and anthocyanin content, maturity, and variety of Vaccinium species, J. Agric. Food Chem., 46(7):2686–2693.
15. Carpenter, J.A., Wang, Y.-P., and Powers, J.J. 1967. Effect of anthocyanin pigments on certain enzymes, Proc. Soc. Exp. Biol. Med., 124(3):702–706.
16. Chen, H., Zuo, Y., and Deng, Y. 2001. Separation and determination of flavonoids and other phenolic compounds in cranberry juice by high-performance liquid chromatography, J. Chromatogr. A., 913(1-2):387–395.
17. Cignarella, A., Nastasi, M., Cavalli, E., and Puglisi, L. 1996. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate, Thrombosis Res., 84(5):311–322.
18. Coget, J. and Merlen, J.F. 1968. Étude clinique d’un nouvel agent de protection vasculaire le Difrarel 20, composé d’anthocyanosides extrait du vaccinum myrtillus, Phlâebologie, 21(2):221–228.
19. Costantino, L., Albasini, A., Rastelli, G., and Benvenuti, S. 1992. “Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors or xanthine oxidase,” Planta Medica, 58:342–344.
20. Cristoni, A. and Magistretti, M.J. 1987. Antiulcer and healing activity of Vaccinium myrtillus anthocyanosides, Farmaco, 42(2):29–43.
21. Eck, P. 1988. Blueberry Science, Rutgers Univ. Press, New Brunswick, NJ.
22. Edenharder, R., Kurz, P., John, K., Burgard, S., and Seeger, K. 1994. In vitro effect of vegetable and fruit juices on the mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, Food Chem. Toxicol., 32(5):443–459.
23. Fellers, C.R., Redmon, B.C., and Parrott, E.M. 1933. Effect of cranberries on urinary acidity and blood alkali reserve, J. Nutr., 6:455-463.
24. Fitzpatrick, D.F., Hirschfield, S.L., Ricci, T., Jantzen, P., and Coffey, R.G. 1995. Endothelium-dependent vasorelaxation caused by various plant extracts, J. Cardiovascular Pharmacol., 26(1):90-95.
25. Fleet, J.C., 1994. New suppport for a folk remedy: cranberry juice reduces bacteriuria and pyuria in elderly women, Nutr. Rev., 52(5):168-178.
26. Griffiths, L.A. and Smith, G.E. 1972. Metabolism of myricetin and related compounds in the rat metabolite formation in vivo and by the intestinal microflora in vitro, Biochem. J., 130:141–151.
27. Heinonen, I.M., Meyer, A.S., and Frankel, E.N. 1998. Antioxidant activity of berry phenolics on human low-density lipoprotein and liposome oxidation, J. Agric. Food Chem., 46(10):4107–4112.
28. Howe, S.M. and Bates, P., 1987. The cranberry juice cure: fact or fiction, AUAA J., July-September pp. 13, 16.
29. Howell, A.B., Leahy, M., Kurawska, E., and Guthrie, N. 2001. In vivo evidence that cranberry proanthocyanidins inhibit adherence of p-fimbriated E. coli bacteria to uroepithelial cells, Abstract 244.1, FASEB J., 15(4):A284.
30. Jackson, B. and Hicks, L.E. 1997. Effect of cranberry juice on urinary pH in older adults, Home Healthcare Nurse, 15(3):199–202.
31. Jayle, G.E., Aubry, M., Gavini, H., Braccini, G., and de la Baume, C. 1965. Étude concernant l’action sur la vision nocturne, Ann. Oculistique, 198(6):556–562.
32. Jonadet, M., Meunier, M.T., Bastide, J., and Bastide, P. 1983. Anthocyanosides extraits de Vitis vinifera, de Vaccinium myrtillus et de Pinus maritimus. I. Activités inhibitrices vis-á-vis de l’élastase in vitro; II. Activités angioprotectrices comparées in vivo, J. Pharm. Belg., 38(1):41–46.
33. Joseph, J.A., Denisova, N., Fisher, D., Shukitt-Hale, B., Prior, R., and Cao, G. 1998. Membrane and receptor modifications of oxidative stress vulnerability in aging. Nutritional considerations, Ann. NY Acad. Sci., 854(11):268–276.
34. Joseph, J.A., Shukitt-Hale, B., Denisova, N.A., Bielinski, D., Martin, A., McEwen, J.J., and Bickford, P.C. 1999. Reversals in age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J. Neuroscience, 19(18):8114–8121.
35. Kader, F., Rovel, B., Giradin, M., and Metche, M. 1996. Fractionation and identification of the phenolic compounds of highbush blueberries (Vaccinium corymbosum, L.), Food Chem., 55(1):35–40.
36. Kalt, W. and Dufour, D. 1997. Health functionality of blueberries, HortTechnol., 7(3):216–222.
37. Kinney, A.B. and Blount, M. 1979. Effect of cranberry juice on urinary pH, Nursing Res., 28(5):287–290.
38. Kontiokari, T., Sundqvist, K., Nuutinen, M., Pokka, T., Koskela, M., and Uhari, M. 2001. Randomised trial of cranberry-lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women, Brit. Med. J., 322(7302):1571–1575.
39. Laplaud, P.M., Lelubre, A., and Chapman, M.J. 1997. Antioxidant action of Vaccinium mytril-lus extract on human low density lipoproteins in vitro: initial observations, Fund. Clin. Pharmacol., 11(1):35–40.
40. Leaver, R.B., 1996. Cranberry juice: an update on cranberry juice, focusing on its use in the prevention and treatment of urinary tract infection, its effect on the formation of urinary stones and on the control of mucus formation, Prof. Nurse, 11(8):525-526.
41. Lietti, A., Cristoni, A., and Picci, M. 1976a. Studies on Vaccinium myrtillus anthocyanosides. I. Vasoprotective and anti-inflammatory activity, Arzneim.-Forsch., 26(5):829–832
42. Lietti, A. and Forni, G. 1976b. Studies on Vaccinium myrtillus anthocyanosides. II. Aspects of anthocyanins pharmacokinetics in the rat, Arzneim.-Forsch., 26(5):832–835.
43. Magnasco, A. 1966. Influenza degli antocianosidi sulla soglia retinica differenziale mesopica, Ann. Ottalmologia Clin. Oculistica, 92(3):188-193.
44. Marniemi, J., Hakala, P., Maki, J., and Ahotupa, M. 2000. Partial resistance of low density lipoprotein to oxidation in vivo after increased intake of berries, Nutr. Metab. Cardiovasc. Dis., 10(6):331–337.
45. Matsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., and Matsumoto, K. 2001a. α-Glucosidase inhibitory action of natural acylated anthocyanins. 1. Survey of natural pigments with potent inhibitory activity, J. Agric. Food Chem., 49(4):1948–1951.
46. Matsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., and Matsumoto, K. 2001b. α-Glucosidase inhibitory action of natural acylated anthocyanins. 2. α-Glucosidase inhibition by isolated acylated anthocyanins, J. Agric. Food Chem., 49(4):1952–1956.
47. Mazza, G., and Miniati, E. 1993. Anthocyanins in Fruits, Vegetables, and Grains, CRC Press, Inc., Boca Raton, FL.
48. Meiers, S., Kemeny, M., Weyand, U., Gastpar, R., von Angerer, E., and Marko, D. 2001. The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor, J. Agric. Food Chem., 49(2):958–962.
49. Meyer, A.S., Heinonen, M., and Frankel, E.N. 1998. Antioxidant interactions of catechin, cyanidin, caffeic acid, quercetin, and ellagic acid on human LDL oxidation, Food Chem., 61(1):71–75.
50. Mian, E., Curri, S.B., Lietti, A., and Bombardelli, E. 1977. Anthocyanosides and the walls of the microvessels: further aspects of the mechanism of action of their protective effect in syndromes due to abnormal capillary fragility, Minerva Med., 68(52):3565–3581.
51. Miyazawa, T., Nakagawa, K., Kudo, M., Muraishi, K., and Someya, K. 1999. Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside, into rats and humans, J. Agric. Food Chem., 47(3):1083–1091.
52. Monane, M., Gurwitz, J., Lipsitz, L., Glynn, R., Choodnovskiy, I., and Avorn, J. 1995. Epidemiologic and diagnostic aspects of bacteriuria: a longitudinal study in older women, J. Am. Geriatric Soc., 43(6):618–622.
53. Moore, J.N. 1994. The blueberry industry of North America, HortTechol., 4(2):96-102.
54. 1 biosynthesis in Aspergillus flavus by antho-cyaninidins and related flavonoids, J. Agric Food Chem., 47(3):1230–1235.
55. Ofek, I., Goldhar, J., and Sharon, N. 1996. Anti-Escherichia coli adhesin activity of cranberry and blueberry juices, in Toward Anti-Adhesion Therapy for Microbial Diseases, Kahane and Ofek, eds., Plenum Press, New York, pp. 179–183.
56. Ofek, I., Goldhar, J., Zafriri, D., Lis, H., Adar, R, and Sharon, N. 1991. Anti-Escherichia coli adhesin activity of cranberry and blueberry juices, New Engl. J. Med., 324(22):1599.
57. Ohnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1994. Inhibitory effects of chlorogenic acids on linoleic acid peroxidation and haemoly-sis, Phytochem., 36(3):579–583.
58. Ou, S., Kwok, K.-C., Li, Y., and Fu, L. 2001. In vitro study of possible role of dietary fiber in lowering postprandial serum glucose, J. Agric. Food Chem., 49(2):1026–1029.
59. Papas, P. N. Brusch, C.A. and Cresia, G.C., 1966. Cranberry juice in the treatment of urinary tract infections, Southwestern Med., 47(1):17-20.
60. Pedersen, C.B., Kyle, J., Jenkinson, A.M., Gardner, P.T., McPhail, D.B., and Duthie, G.G. 2000. Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers, Eur. J. Clin. Nutr., 54(5):405–08.
61. Reid, G., Hsiehl, J., Potter, P., Mighton, J., Lam, D., Warren, D., and Stephenson, J. 2001. Cranberry juice consumption may reduce biofilms on uroepithelial cells: pilot study in spinal cord injured patients, Spinal Cord, 39(1):26–30.
62. Rice-Evans, C.A., Miller, N.J., Bolwell, P.G., Bramley, P.M., and Pridham, J.B. 1995. The relative antioxidant activities of plant-derived polyphenolic flavonoids, Free Rad. Res., 22(4):375–383.
63. Rogers, J., 1991. Pass the cranberry juice, Nursing Times, 87(48):36-37.
64. Saija, A., Princi, P., D’Amico, N., DePasquale, R., and Costa, G., 1990. Effect of Vaccinium myrtillus anthocyanins on triiodothyronine transport into brain in the rat, Pharmacol. Res., 22(1):59–60.
65. Satué-Gracia, M.T., Heinonen, M., and Frankel, E.N. 1997. Anthocyanins as antioxidants on human low-density lipoprotein and lecithin-liposome systems, J. Agric. Food Chem., 45(9):3362–3367.
66. Scialdone, D. 1966. L’azione delle antocianine sul senso luminoso, Ann. Ottalmologia clin. oculistica, 92(1):43–51.
67. Schmidt, D.R. and Sobota, A.E. 1988. An examination of the anti-adherence activity of cranberry juice on urinary and nonurinary bacterial isolates, Microbios, 55(224-225):173–181.
68. Schramm, D.D. and J.B. German. 1998. Potential effects of flavonoids on the etiology of vascular disease, J. Nutr. Biochem., 9(10):560–566.
69. Smith, M.A.L., Marley, K.A., Seigler, D., Singletary, K.W., and Meline, B. 2000. Bioactive properties of wild blueberry fruits, J. Food Sci., 65(2):352–356.
70. Sobota, A.E. 1984. Inhibition of bacterial adherence by cranberry juice: potential use for the treatment of urinary tract infections, J. Urology, 131(5):1013–1016.
71. Trevithick, J.R. and Mitton, K.P. 1999. Antioxidants and diseases of the eye, Ch. 24 in Antioxidant Status, Diet, Nutrition, and Health, A.M. Pappas, ed., CRC Press, Boca Raton, FL, pp. 545–565.
72. Tsuda, T., Horio, F., and Osawa, T. 1998. Dietary cyanidin 3-O-β-D-glucoside increases ex vivo oxidation resistance of serum in rats, Lipids, 33(6):583–587.
73. Tsuda, T., Ohshima, K., Kawakishi, S., and Osawa, T. 1996. Oxidation products of cyanidin 3-O-β-D-glucoside with a free radical initiator, Lipids, 31(12):1259–1263.
74. Tsuda, T., Watanabe, M., Ohshima, K., Norinobu, S., Choi, S.-W., Kawakishi, S., and Osawa, T. 1994. Antioxidative activity of the anthocyanin pigments cyanidin 3-O-β-D-glucoside and cyanidin, J. Agric. Food Chem., 42(11):2407–2410.
75. Varma, S.D. 1986. Inhibition of aldose reductase by flavonoids: possible attentuation of diabetic complications, in Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological, and Structure-Activity Relationships, Alan R. Liss, Inc., pp. 343–358.
76. Velioglu, Y.S., Mazza, G., Gao, L., and Oomah, B.D. 1998. Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products, J. Agric. Food Chem., 46(10):4113–4117.
77. Villata, M. 1998. Cultivated blueberries: a true-blue baking ingredient, Cereal Foods World, 43(3):128–130.
78. Walker, E.B., Barney, D.P., Mickelsen, J.N., Walton, R.J. and Mickelsen Jr, R.A., 1997. Cranberry concentrate: UTI prophylaxis, J. Fam. Prac., 45(2):167-168.
79. Wang, H., Cao, G., and Prior, R.L. 1997. Oxygen radical absorbing capacity of anthocyanins, J. Agric. Food Chem, 45(2):304–309.
80. Weiss, E.I., Lev-Dor, R., Kashamn, Y., Goldhar, J., Sharon, N., and Ofek, I. 1998. Inhibiting interspecies coaggregation of plaque bacteria with a cranberry juice constituent, J. Am. Dent. Assoc., 129(12):1719–1723.
81. Wilson, T. and Marley, J.C. 2001. Effects of cranberry juice consumption on platelet aggregation, FASEB J., 15(4):A286.
82. Youdim K.A., Shukitt-Hale, B., Martin, A., Bickford, P.C., and Joseph, J.A. 2000. Short-term dietary supplementation of blueberry polyphenolics: beneficial effects on aging brain performance and peripheral tissue function, Nutr. Neuroscience, (3):383-397.
83. Zafriri, D., Ofek, I., Adar, R., Pocino, M. and Sharon, N., 1989. Inhibitory activity of cranberry juice on adherence of Type 1 and Type P fimbriated Escherichia coli to eucaryotic cells, Antimicrobial Agents and Chemotherapy, 33(1):92-98.
84. Zaragozá, F., Iglesias, I., and Benedí, J. 1985. Estudio comparativo de los efectos antiagre-gantes de los antocianósidos y otros agentes, Archiv. Farmacol. Toxicol., 11(3):183-188