Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta

Journal of Nutrition

Volumn 128, Issue 12, 1998, Pages 2324-2333

  Andriambeloson, Emile ^a   Magnier, Céline ^a   Haan Archipoff, Gisèle ^a   Lobstein, Annelise ^a   Anton, Robert ^a   Beretz, Alain ^a   Stoclet, Jean Claude ^a   Andriantsitohaina, Ramaroson ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Anthocyanins; Nitric oxide; Polyphenols; Tannins; Vasorelaxation

Indexed keywords

ANTHOCYANIN; BENZOIC ACID; CAFFEIC ACID; COUMARIC ACID; CYANIDIN CHLORIDE; DELPHINIDIN; EPICATECHIN; FLAVONOL; GALLIC ACID; MALVIDIN CHLORIDE; NITRIC OXIDE; PHENOL DERIVATIVE; POLYPHENOL; TANNIN; VANILLIC ACID;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; DIETARY INTAKE; MALE; NONHUMAN; RAT; SMOOTH MUSCLE RELAXATION; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0032430844     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/128.12.2324     Document Type: Article

References (32)

1. Andriambeloson, E., Kleschyov, A. L., Muller, B., Beretz, A., Stoclet, J. C. & Andriantsitohaina R. (1997) Nitric oxide production and endothelium-dependent vasorelaxation induced by wine polyphenols in rat aorta. Br. J. Pharmacol. 120: 1053-1058.
2. Andriambeloson, E., Stoclet, J. C. & Andriantsitohaina, R. (1996) Effets vasculaires d'extraits végétaux contenant des dérivés polyphénoliques. In: Polyphenols Communications 96 (Vercauteren, J., Chèze, G., Dumon, M. C. & Weber, J. F., eds.), Vol. 2, pp. 421-422. Groupe Polyphénols, Bordeaux, France.
3. Barton, M., Cosentino, F., Brandes, R. P., Moreau, P., Shaw, S. & Luscher, T. F. (1997) Anatomic heterogeneity of vascular aging. Role of nitric oxide and endothelin. Hypertension 30: 817-824.
4. Beretz, A., Anton, R. & Stoclet, J. C. (1978) Flavonoid compounds are potent inhibitors of cyclic AMP phosphodiesterase. Experientia 34: 1054-1055.
5. Beretz, A., Stierte, A., Anton, R., Cazenave, J. P. (1982) Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacyclin. Biochem. Pharmacol. 31: 3597-3600.
6. Beretz, A., Stoclet, J. C. & Anton, R. (1980) Inhibition of isolated rat aorta contraction by flavonoids. Possible correlation with cAMP phosphodiestrase inhibition. Planta Med. 39: 236 (abs).
7. Cloutier, M. M. & Rohrbach, M. S. (1989) Effects of tannins from different sources on airway epithelial and platelet function. Lung 167: 117-128.
8. Da Silva, J. M. R., Rigaud, J., Cheynier, V., Cheminat, A. & Moutounet, M. (1991) Procyanidin dimers and trimers from grape seeds. Phytochemistry 30: 1259-1264.
9. Delcour, J. A., Verhulst, L. L., Geys, R. & Deliever, H. (1981) Trimeric and oligomeric flavonoids in beer: a joint application of Sephadex LH-20 and reversed-phase gradient elution high performance liquid chromatography. J. Inst. Brew. 87: 391-393.
10. Duarte, J., Vizcaino, F. P., Utrilla, P., Jiménez, J., Tamargo, J. & Zarzuelo, A. (1993) Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships. Gen. Pharmacol. 24: 857-862.
11. Fitzpatrick, D. F., Hirschfield, S. L. & Coffey, R. G. (1993) Endothelium-dependent vasorelaxing activity of wine and other grape products. Am. J. Physiol. 265: H774-H778.
12. Fitzpatrick, D. F., Hirschfield, S. L., Ricci, T., Jantzen, P. & Coffey R. G. (1995) Endothelium-dependent vasorelaxation caused by various plant extracts. J. Cardiovasc. Res. 26: 90-95.
13. 1 receptor activation. Br. J. Pharmacol. 122: 200P (abs).
14. Furchgott, R. F., Vanhoutte, P. M. (1989) Endothelium-derived relaxing and contracting factors. FASEB J. 3: 2007-2018.
15. Gryglewski, R. J., Palmer, R. M., Moncada, S. (1986) Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320: 454-456.
16. Herrera, M. D., Zarzuelo, A., Jiménez, J., Marhuenda, E. & Duarte, J. (1996) Effects of flavonoids on rat aortic smooth muscle contractility: structure-activity relationships. Gen. Pharmacol. 27: 273-277.
17. Hertog, M.G.L., Feskens, E.J.M., Hollman, P.C.H., Katan, M. B. & Kromhout, D. (1993) Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 22: 1007-1011.
18. Hertog, M.G.L., Hollman P.C.H. & Katan M. B. (1992) Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J. Agric. Food. Chem. 40: 2379-2383.
19. Hongo, K., Nakagomi, T., Kassell, N. F., Sasaki, T., Lehman, M., Vollmer, D. G., Tsukahara, T., Ogawa, H., Torner, J. (1988) Effects of aging and hypertension on the endothelium-dependent vascular relaxation in rat carotid artery. Stroke 19: 892-897.
20. Koga, T., Takata, Y., Kobayashi, Takishita, S., Ymashita, Y., Fujishima, M. (1989) Age and hypertension promote endothelium-dependent contraction to acetylcholine in the aorta of the rats. Hypertension 14: 542-548.
21. Künhau, J. (1976) The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev. Nutr. Diet. 24: 117-191.
22. Nagel, C. W. & Wolf, L. W. (1979) Changes in the anthocyanins, flavonoids and hydroxycinnamic esters during fermentation and ageing of Merieot and Cabernet Sauvignon. Am. J. Enology Viticulture 30: 111-116.
23. Paganga, G. & Rice-Evans, C. A. (1997) The identification of flavonoids as glycosides in human plasma. FEBS Lett. 401: 78-82.
24. Rapoport, R. M. & Murad, F. (1983) Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP. Circ. Res. 52: 352-357.
25. Renaud, S. & De Lorgeril, M. (1992) Wine, alcohol, platelets, and French paradox for coronary heart disease. Lancet 339: 1523-1526.
26. Taddei, S., Agostino, V., Mattei, P., Ghiadoni, L., Gennari, A., Fasolo, C. B., Sudano, I. & Salvetti, A. (1995) Aging and endothelial function in normotensive subjects and patients with essential hypertension. Circulation 91: 1981-1987.
27. Teissedre, P. L., Frankel, E. N., Waterhouse, A. L., Peleg, H. & German J. B. (1996) Inhibition of in vitro human LDL oxidation by phenolic antioxidants from grapes and wines. J. Sci. Food. Agric. 70: 55-61.
28. Timberlake, C. F. (1981) Anthocyanins in fruits and vegetables. In: Recent Advances in the Biochemistry of Fruits and Vegetables (Friends, J. & Rhodes, M.J.C., eds.), Vol. 1, pp. 137-139. Academic Press, London.
29. Ulbricht, T. L. & Southgate, D. A. (1991) Coronary heart disease: seven dietary factors. Lancet 338: 985-992.
30. Vane, J. R., Anggard, E. E. & Bolting, R. M. (1990) Regulatory functions of the vascular endothelium. N. Engl. J. Med. 323: 27-36.
31. Vanhoutte, P. M. (1989) Endothelium and control of vascular function. Hypertension 13: 658-667.
32. Wagner, M. & Bladt, S. (1996) Plant Drug Analysis, 2nd Ed. Springer Verlag, Berlin.