The selective A2A receptor antagonist SCH 58261 protects from neurological deficit, brain damage and activation of p38 MAPK in rat focal cerebral ischemia

Brain Research

Volumn 1073-1074, Issue 1, 2006, Pages 470-480

  Melani, Alessia ^a   Gianfriddo, Marco ^a,c   Vannucchi, Maria Giuliana ^a   Cipriani, Sara ^a   Baraldi, Pier Giovanni ^b   Giovannini, Maria Grazia ^a   Pedata, Felicita ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c Siena Biotech SpA   (Italy)

Author keywords

A2A receptor; Adenosine; Cerebral ischemia; MAPK; Middle cerebral artery occlusion

Indexed keywords

5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPROTECTIVE AGENT; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR CORTEX; WESTERN BLOTTING; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; BRAIN INJURY; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; DISEASE MODEL; HEMISPHERIC DOMINANCE; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; MOTOR ACTIVITY; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; PATHOLOGY; PHYSIOLOGY; WISTAR RAT;

ANIMALIA; HUMAN ECHOVIRUS 1;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BRAIN; BRAIN INJURIES; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; FUNCTIONAL LATERALITY; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; MOTOR ACTIVITY; NERVOUS SYSTEM DISEASES; NEUROLOGIC EXAMINATION; NEUROPROTECTIVE AGENTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIMIDINES; RATS; RATS, WISTAR; TRIAZOLES;

EID: 33644956171     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.12.010     Document Type: Article

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