Phosphorylation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase after transient forebrain ischemia in mice

Neuroscience Letters

Volumn 294, Issue 2, 2000, Pages 117-120

  Takagi, Yasushi ^a,b   Nozaki, Kazuhiko ^a   Sugino, Toshiyuki ^a   Hattori, Itaro ^a   Hashimoto, Nobuo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Apoptosis; c Jun NH2 terminal kinase; Immediate early genes; Mouse; p38 Mitogen activated protein kinase; Transient forebrain ischemia

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CONTROLLED STUDY; FOREBRAIN; IMMEDIATE EARLY GENE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANIMAL; APOPTOSIS; BLOTTING, WESTERN; CEREBRAL CORTEX; DNA FRAGMENTATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHORYLATION; PROSENCEPHALON; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T;

EID: 0034681060     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01552-4     Document Type: Article

References (19)

1. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia
2. Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy
3. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation
4. Characterization of mitogen-activated protein kinase kinase 4 (MKK4)/ c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinase 2 and 3
5. Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
6. Strain-related differences in susceptibility to transient forebrain ischemia in SV-129 and C57 black/6 mice
7. Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinase after neuronal injury
8. Discordant activation of stress-activated protein kinases or c-Jun NH2-terminal protein kinases in tissues of heat-stressed mice
9. Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver
10. CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults
11. Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice
12. Delayed neuronal cell death in the rat hippocampus in mediated by the mitogen-activated protein kinase signal transduction pathway
13. Thiol-mediated redox regulation of apoptosis. Possible roles of cellular thiols other than glutathione in T cell apoptosis
14. Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus
15. Overexpression of thioredoxin in transgenic mice attenuates focal ischemic damage
16. Proliferation of neuronal precursor cells in the dentate gyrus is accelerated after transient forebrain ischemia in mice
17. Activation of p38 MAPK in microglia after ischemia
18. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
19. Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney