c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation

Transplantation

Volumn 78, Issue 3, 2004, Pages 324-332

  Uehara, Tetsuya ^a   Peng, Xing Xi ^b   Bennett, Brydon ^c   Satoh, Yoshi ^c   Friedman, Glenn ^c   Currin, Robert ^b   Brenner, David A ^d   Lemasters, John ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c Celgene   (United States)

^d Columbia University Medical Center ^*  (United States)

Author keywords

Apoptosis; c Jun; Ischemia reperfusion; Liver; Necrosis; Transplantation; Tumor necrosis factor

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CASPASE 3; CC 401; CYTOCHROME C; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; GRAFT SURVIVAL; LIPID PEROXIDATION; LIVER HISTOLOGY; LIVER INJURY; LIVER ISCHEMIA; LIVER NECROSIS; LIVER TRANSPLANTATION; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; LIVER TRANSPLANTATION; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NECROSIS; RATS; RATS, INBRED LEW; TRANSPLANTATION, ISOGENEIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4143086038     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000128859.42696.28     Document Type: Article

References (34)

1. Furukawa H, Todo S, Imventarza O, et al. Effect of cold ischemia time on the early outcome of human hepatic allografts preserved with UW solution. Transplantation 1991;51(5): 1000.
2. Garcia-Valdecasas Salgado JC. Non beating heart donors as a possible source for liver transplantation. Acta Chir Belg 2000; 100(6): 268.
3. Samarasinghe DA, Tapner M, Farrell GC. role of oxidative stress in hypoxia-reoxygenation injury to cultured rat hepatic sinusoidal endothelial cells. Hepatology 2000; 31(1): 160.
4. Wang L, Roayaie S, Basile J, et al. Graft function and survival depend primarily on host factors in compromised recipient models of orthotopic liver transplantation in the rat. Transplantation 2001; 71(1): 14.
5. Caldwell-Kenkel JC, Currin RT, Tanaka Y, et al. Reperfusion injury to endothelial cells following cold ischemic storage of rat livers. Hepatology 1989; 10(3): 292.
6. Kim JS, Qian T, Lemasters JJ. Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology 2003; 124(2): 494.
7. Rosette C, Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 1996; 274(5290): 1194.
8. Lei K, Davis RJ. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A 2003; 100(5): 2432.
9. Tournier C, Hess P, Yang DD, et al. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 2000; 288(5467): 870.
10. Bradham CA, Stachlewitz RF, Gao W, et al. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology 1997; 25(5): 1128.
11. Bennett BL, Sasaki DT, Murray BW, et al. SP600125, an Anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A 2001; 98(24): 13681.
12. Arai M, Thurman RG, Lemasters JJ. Involvement of kupffer cells and sinusoidal endothelial cells in ischemic preconditioning to rat livers stored for transplantation. Transplant Proc 1999; 31(1-2): 425.
13. Majno G, Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995; 146(1): 3.
14. Kono H, Nakagami M, Rusyn I, et al. Development of an animal model of chronic alcohol-induced pancreatitis in the rat. Am J Physiol Gastrointest Liver Physiol 2001; 280(6): G1178.
15. Bendinelli P, Piccoletti R, Maroni P, and Bernelli-Zazzera, Aet al. The MAP kinase cascades are activated during post-ischemic liver reperfusion. FEBS Lett 1996; 398(2-3): 193.
16. Jaeschke H, Lemasters JJ. Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury. Gastroenterology 2003; 125(4): 1246.
17. Selzner N, Rudiger H, Graf R, et al. Protective strategies against ischemic injury of the liver. Gastroenterology 2003; 125(3): 917.
18. Lemasters JJ. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis. Am J Physiol 199; 276(1 Pt 1): G1.
19. Caldwell-Kenkel JC, Currin RT, Tanaka Y, et al. Kupffer cell activation and endothelial cell damage after storage of rat livers: effects of reperfusion. Hepatology 1991; 13(1): 83.
20. Lentsch AB, Kato A, Yoshidome H, et al. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology 2000; 32(2): 169.
21. Savier E, Shedlofsky SI, Swim AT, et al. The calcium channel blocker nisoldipine minimizes the release of tumor necrosis factor and interleukin-6 following rat liver transplantation. Transpl Int 1992; 5: S398.
22. Lentsch AB, Yoshidome H, Kato A, et al. Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice. Hepatology 1999; 30(6): 1448.
23. Colletti LM, Burtch GD, Remick DG, et al. The production of tumor necrosis factor alpha and the development of a pulmonary capillary injury following hepatic ischemia/reperfusion. Transplantation 1990; 49(2): 268.
24. Cursio R, Gugenheim J, Ricci JE, et al. A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis. FASEB J 1999; 13(2): 253.
25. Natori S, Selzner M, Valentino KL, et al. Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism. Transplantation 1999; 68(1): 89.
26. Weston CR, Davis R.J. The JNK signal transduction pathway. Curr Opin Genet Dev 2002; 12(1): 14.
27. Rudiger HA, Clavien PA. Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver. Gastroenterology 2002; 122(1): 202.
28. Mizukami Y, Yoshioka K, Morimoto S, et al. A novel mechanism of JNK1 activation. Nuclear translocation and activation of JNK1 during ischemia and reperfusion. J Biol Chem 1997; 272(26): 16657.
29. Urata K, Brault A, Rocheleau B, et al. Role of kupffer cells in the survival after rat liver transplantation with long portal vein clamping times. Transpl Int 2000; 13(6): 420.
30. Maundrell K, Antonsson B, Magnenat E, et al. Bcl-2 undergoes phosphorylation by C-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Racl. J Biol Chem 1997; 272(40): 25238.
31. Aguirre V, Uchida T, Yenush L, et al. The C-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000; 275(12): 9047.
32. Aoki H, Kang PM, Hampe J, et al. direct activation of mitochondrial apoptosis machinery by C-Jun N-terminal kinase in Adult cardiac myocytes. J Biol Chem 2002; 277(12): 10244.
33. Schwabe RF, Uchinami H, Qian T, et al. differential requirement for C-Jun NH2-terminal kinase in TNF-alpha and Fas-mediated apoptosis. FASEB J 2004; 18(6): 720.
34. Ozaki M, Deshpande SS, Angkeow P, et al. Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo. FASEB J 2000; 14(2): 418.