Biological activities on T lymphocytes of a baculovirus-expressed chimeric recombinant IgG1 antibody with specificity for the CDR3-like loop on the D1 domain of the CD4 molecule

Clinical Immunology

Volumn 119, Issue 1, 2006, Pages 38-50

  Troadec, Samuel ^a   Bès, Cédric ^a   Chentouf, Myriam ^a   Nguyen, Brigitte ^a   Briant, Laurence ^a   Jacquet, Chantal ^b   Chebli, Karim ^b   Pugnière, Martine ^a   Roquet, Françoise ^a   Cerutti, Martine ^a   Chardès, Thierry ^a  

^a CNRS   (France)

^b INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

Author keywords

Anti CD4; Baculovirus; Chimeric recombinant antibody; Immunotherapy; Signaling; T cell

Indexed keywords

CD4 ANTIGEN; CHIMERIC ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; INTERLEUKIN 2; IONOMYCIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 13B8.2; PHORBOL ESTER; RECOMBINANT ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNIZATION; IN VIVO STUDY; LYMPHOCYTE CULTURE; LYMPHOCYTE DEPLETION; LYMPHOCYTE PROLIFERATION; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE; VIRUS REPLICATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; ANTIGEN PRESENTATION; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS, CD3; ANTIGENS, CD4; BACULOVIRIDAE; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CELL PROLIFERATION; EPITOPES; GENE EXPRESSION; HELA CELLS; HIV LONG TERMINAL REPEAT; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; INTERLEUKIN-2; IONOMYCIN; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED DBA; MICE, TRANSGENIC; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE;

EID: 33644774345     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2005.11.013     Document Type: Article

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