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Volumn 90, Issue 2, 1997, Pages 745-753

Modulation of Bcl-2 protein by CD4 cross-linking: A possible mechanism for lymphocyte apoptosis in human immunodeficiency virus infection and for rescue of apoptosis by interleukin-2

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; INTERLEUKIN 2; ONCOPROTEIN;

EID: 0030877601     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.2.745.745_745_753     Document Type: Article
Times cited : (74)

References (38)
  • 2
    • 0026517545 scopus 로고
    • Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals
    • Groux H, Torpier G, Monte D, Mouton Y, Capron A, Ameisen JC: Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals. J Exp Med 175:331, 1992
    • (1992) J Exp Med , vol.175 , pp. 331
    • Groux, H.1    Torpier, G.2    Monte, D.3    Mouton, Y.4    Capron, A.5    Ameisen, J.C.6
  • 3
    • 0027497028 scopus 로고
    • Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals
    • Oyaizu N, McCloskey TW, Coronesi M, Chirmule N, Kalyanaraman VS, Pahwa S: Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals. Blood 82:3392, 1993
    • (1993) Blood , vol.82 , pp. 3392
    • Oyaizu, N.1    McCloskey, T.W.2    Coronesi, M.3    Chirmule, N.4    Kalyanaraman, V.S.5    Pahwa, S.6
  • 4
    • 0029034517 scopus 로고
    • Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden
    • Muro-Cacho CA, Pantaleo G, Fauci AS: Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J Immunol 154:5555, 1995
    • (1995) J Immunol , vol.154 , pp. 5555
    • Muro-Cacho, C.A.1    Pantaleo, G.2    Fauci, A.S.3
  • 6
    • 0027960659 scopus 로고
    • Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion
    • Oyaizu N, McCloskey TW, Than S, Hu R, Kalyanaraman VS, Pahwa S: Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion. Blood 84:2622, 1994
    • (1994) Blood , vol.84 , pp. 2622
    • Oyaizu, N.1    McCloskey, T.W.2    Than, S.3    Hu, R.4    Kalyanaraman, V.S.5    Pahwa, S.6
  • 8
    • 0029794255 scopus 로고    scopus 로고
    • Activation of the CD95 (APO-1/Fas) system in T cells from human immunodeficiency virus type-1-infected children
    • Baumler CB, Bohler T, Herr I, Benner A, Krammer PH, Debatin KM: Activation of the CD95 (APO-1/Fas) system in T cells from human immunodeficiency virus type-1-infected children. Blood 88:1741, 1996
    • (1996) Blood , vol.88 , pp. 1741
    • Baumler, C.B.1    Bohler, T.2    Herr, I.3    Benner, A.4    Krammer, P.H.5    Debatin, K.M.6
  • 9
    • 9044232148 scopus 로고    scopus 로고
    • The Fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells
    • Gehri R, Hahn S, Rothen M, Steuerwald M, Nuesch R, Erb P: The Fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells. AIDS 10:9, 1996
    • (1996) AIDS , vol.10 , pp. 9
    • Gehri, R.1    Hahn, S.2    Rothen, M.3    Steuerwald, M.4    Nuesch, R.5    Erb, P.6
  • 10
    • 0029992895 scopus 로고    scopus 로고
    • Fas-mediated apoptosis of CD4+ and CDS+ T cells from human immunodeficiency virus-infected persons: Differential in vitro preventive effect of cytokines and protease antagonists
    • Estaquier J, Tanaka M, Suda T, Nagata S, Golstein P, Ameisen JC: Fas-mediated apoptosis of CD4+ and CDS+ T cells from human immunodeficiency virus-infected persons: Differential in vitro preventive effect of cytokines and protease antagonists. Blood 87:4959, 1996
    • (1996) Blood , vol.87 , pp. 4959
    • Estaquier, J.1    Tanaka, M.2    Suda, T.3    Nagata, S.4    Golstein, P.5    Ameisen, J.C.6
  • 11
    • 0029882175 scopus 로고    scopus 로고
    • Programmed cell death in peripheral lymphocytes from HIV-infected persons: Increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression
    • Gougeon ML, Lecoeur H, Dulioust A, Enouf MG, Crouvoiser M, Goujard C, Debord T, Montagnier L: Programmed cell death in peripheral lymphocytes from HIV-infected persons: Increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression. J Immunol 156:3509, 1996
    • (1996) J Immunol , vol.156 , pp. 3509
    • Gougeon, M.L.1    Lecoeur, H.2    Dulioust, A.3    Enouf, M.G.4    Crouvoiser, M.5    Goujard, C.6    Debord, T.7    Montagnier, L.8
  • 12
    • 0029048581 scopus 로고
    • Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals
    • Katsikis PD, Wunderlich ES, Smith CA, Herzenberg LA, Herzenberg LA: Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J Exp Med 181:2029, 1995
    • (1995) J Exp Med , vol.181 , pp. 2029
    • Katsikis, P.D.1    Wunderlich, E.S.2    Smith, C.A.3    Herzenberg, L.A.4    Herzenberg, L.A.5
  • 13
    • 0029041822 scopus 로고
    • Expression of the Fas antigen in patients infected with human immunodeficiency virus
    • McCloskey TW, Oyaizu N, Kaplan M, Pahwa S: Expression of the Fas antigen in patients infected with human immunodeficiency virus. Cytometry 22:111, 1995
    • (1995) Cytometry , vol.22 , pp. 111
    • McCloskey, T.W.1    Oyaizu, N.2    Kaplan, M.3    Pahwa, S.4
  • 14
    • 0028780735 scopus 로고
    • Apoptosis. Death gets a brake
    • Wyllie AH: Apoptosis. Death gets a brake [news; comment]. Nature 369:272, 1994
    • (1994) Nature , vol.369 , pp. 272
    • Wyllie, A.H.1
  • 15
    • 0029025515 scopus 로고
    • Apoptosis: O death, where is thy sting?
    • Henkart PA: Apoptosis: O death, where is thy sting? J Immunol 154:4905, 1995
    • (1995) J Immunol , vol.154 , pp. 4905
    • Henkart, P.A.1
  • 16
    • 0027938156 scopus 로고
    • Bcl-2 and Bcl-x: Regulatory switches for lymphoid death and survival
    • Nunez G, Merino R, Grillot D, Gonzalez-Garcia M: Bcl-2 and Bcl-x: Regulatory switches for lymphoid death and survival. Immunol Today 15:582, 1994
    • (1994) Immunol Today , vol.15 , pp. 582
    • Nunez, G.1    Merino, R.2    Grillot, D.3    Gonzalez-Garcia, M.4
  • 17
    • 0022546957 scopus 로고
    • Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma
    • Tsujimoto Y, Croce CM: Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci USA 83:5214, 1986
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5214
    • Tsujimoto, Y.1    Croce, C.M.2
  • 18
    • 0022971142 scopus 로고
    • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14; 18) translocation
    • Cleary ML, Smith SD, Sklar J: Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14; 18) translocation. Cell 47:19, 1986
    • (1986) Cell , vol.47 , pp. 19
    • Cleary, M.L.1    Smith, S.D.2    Sklar, J.3
  • 19
    • 0028017574 scopus 로고
    • Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils
    • Iwai K, Miyawaki T, Takizawa T, Konno A, Ohta K, Yachie A, Seki H, Taniguchi N: Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils. Blood 84:1201, 1994
    • (1994) Blood , vol.84 , pp. 1201
    • Iwai, K.1    Miyawaki, T.2    Takizawa, T.3    Konno, A.4    Ohta, K.5    Yachie, A.6    Seki, H.7    Taniguchi, N.8
  • 20
    • 0027511735 scopus 로고
    • APO-1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: Correlation with bcl-2 oncogene expression
    • Mapara MY, Bargou R, Zugck C, Dohner H, Ustaoglu F, Jonker RR, Krammer PH, Dorken B: APO-1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: Correlation with bcl-2 oncogene expression. Eur J Immunol 23:702, 1993
    • (1993) Eur J Immunol , vol.23 , pp. 702
    • Mapara, M.Y.1    Bargou, R.2    Zugck, C.3    Dohner, H.4    Ustaoglu, F.5    Jonker, R.R.6    Krammer, P.H.7    Dorken, B.8
  • 21
    • 0028299065 scopus 로고
    • The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis
    • Salmon M, Pilling D, Borthwick NJ, Viner N, Janossy G, Bacon PA, Akbar AN: The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis. Eur J Immunol 24:892, 1994
    • (1994) Eur J Immunol , vol.24 , pp. 892
    • Salmon, M.1    Pilling, D.2    Borthwick, N.J.3    Viner, N.4    Janossy, G.5    Bacon, P.A.6    Akbar, A.N.7
  • 22
    • 0028226620 scopus 로고
    • Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes
    • Yoshino T, Kondo E, Cao L, Takahashi K, Hayashi K, Nomura S, Akagi T: Inverse expression of bcl-2 protein and Fas antigen in lymphoblasts in peripheral lymph nodes and activated peripheral blood T and B lymphocytes. Blood 83:1856, 1994
    • (1994) Blood , vol.83 , pp. 1856
    • Yoshino, T.1    Kondo, E.2    Cao, L.3    Takahashi, K.4    Hayashi, K.5    Nomura, S.6    Akagi, T.7
  • 23
    • 0026497684 scopus 로고
    • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
    • Miyawaki T, Uehara T, Nibu R, Tsuji T, Yachie A, Yonehara S, Taniguchi N: Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 149:3753, 1992
    • (1992) J Immunol , vol.149 , pp. 3753
    • Miyawaki, T.1    Uehara, T.2    Nibu, R.3    Tsuji, T.4    Yachie, A.5    Yonehara, S.6    Taniguchi, N.7
  • 25
    • 0030293533 scopus 로고    scopus 로고
    • IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection: Correlation with its ability to block culture-induced down-modulation of Bcl-2
    • Adachi Y, Oyaizu N, Than S, McCloskey TW, Pahwa S: IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection: Correlation with its ability to block culture-induced down-modulation of Bcl-2. J Immunol 157:4184, 1996
    • (1996) J Immunol , vol.157 , pp. 4184
    • Adachi, Y.1    Oyaizu, N.2    Than, S.3    McCloskey, T.W.4    Pahwa, S.5
  • 26
    • 0025278511 scopus 로고
    • Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry
    • Loken MR, Brosnan JM, Bach BA, Ault KA: Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry. Cytometry 11:453, 1990
    • (1990) Cytometry , vol.11 , pp. 453
    • Loken, M.R.1    Brosnan, J.M.2    Bach, B.A.3    Ault, K.A.4
  • 27
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609, 1993
    • (1993) Cell , vol.74 , pp. 609
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 29
    • 0030067103 scopus 로고    scopus 로고
    • Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti-apoptotic (bcl-2, bcl-xL) but not proapoptotic (bax, bcl-xS) gene expression
    • Akbar AN, Borthwick NJ, Wickremasinghe RG, Panayoitidis P, Pilling D, Bofill M, Krajewski S, Reed JC, Salmon M: Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti-apoptotic (bcl-2, bcl-xL) but not proapoptotic (bax, bcl-xS) gene expression. Eur J Immunol 26:294, 1996
    • (1996) Eur J Immunol , vol.26 , pp. 294
    • Akbar, A.N.1    Borthwick, N.J.2    Wickremasinghe, R.G.3    Panayoitidis, P.4    Pilling, D.5    Bofill, M.6    Krajewski, S.7    Reed, J.C.8    Salmon, M.9
  • 30
    • 0030022782 scopus 로고    scopus 로고
    • Differential regulation of bcl-2 and bcl-x by CD3, CD28, and the IL-2 receptor in cloned CD4+ helper T cells. a model for the long-term survival of memory cells
    • Mueller DL, Seiffert S, Fang W, Behrens TW: Differential regulation of bcl-2 and bcl-x by CD3, CD28, and the IL-2 receptor in cloned CD4+ helper T cells. A model for the long-term survival of memory cells. J Immunol 156:1764, 1996
    • (1996) J Immunol , vol.156 , pp. 1764
    • Mueller, D.L.1    Seiffert, S.2    Fang, W.3    Behrens, T.W.4
  • 31
    • 0030026869 scopus 로고    scopus 로고
    • IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis. Correlation with induction of Bcl-2
    • Mor F, Cohen IR: IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis. Correlation with induction of Bcl-2. J Immunol 156:515, 1996
    • (1996) J Immunol , vol.156 , pp. 515
    • Mor, F.1    Cohen, I.R.2
  • 32
    • 0027537118 scopus 로고
    • Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2
    • Deng G, Podack ER: Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc Natl Acad Sci USA 90:2189, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2189
    • Deng, G.1    Podack, E.R.2
  • 33
    • 0029768092 scopus 로고    scopus 로고
    • Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells
    • Desbarats J, Freed JH, Campbell PA, Newell MK: Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells. Proc Natl Acad Sci USA 93:11014, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11014
    • Desbarats, J.1    Freed, J.H.2    Campbell, P.A.3    Newell, M.K.4
  • 34
    • 0030037138 scopus 로고    scopus 로고
    • bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis
    • Lee RK, Spielman J, Podack ER: bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis. Int Immunol 8:991, 1996
    • (1996) Int Immunol , vol.8 , pp. 991
    • Lee, R.K.1    Spielman, J.2    Podack, E.R.3
  • 35
    • 0028917923 scopus 로고
    • Bcl-2 blocks degranulation but not fas-based cell-mediated cytotoxicity
    • Chiu VK, Walsh CM, Liu CC, Reed JC, Clark WR: Bcl-2 blocks degranulation but not fas-based cell-mediated cytotoxicity. J Immunol 154:2023, 1995
    • (1995) J Immunol , vol.154 , pp. 2023
    • Chiu, V.K.1    Walsh, C.M.2    Liu, C.C.3    Reed, J.C.4    Clark, W.R.5
  • 36
    • 0025218885 scopus 로고
    • Human immunodeficiency virus type 1 envelope glycoprotein gp120 produces immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA
    • published erratum appears in Proc Natl Acad Sci USA 87:4022, 1990
    • Oyaizu N, Chirmule N, Kalyanaraman VS, Hall WW, Pahwa R, Shuster M, Pahwa S: Human immunodeficiency virus type 1 envelope glycoprotein gp120 produces immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA [published erratum appears in Proc Natl Acad Sci USA 87:4022, 1990]. Proc Natl Acad Sci USA 87:2379, 1990
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2379
    • Oyaizu, N.1    Chirmule, N.2    Kalyanaraman, V.S.3    Hall, W.W.4    Pahwa, R.5    Shuster, M.6    Pahwa, S.7
  • 37
    • 0029811148 scopus 로고    scopus 로고
    • Rational interleukin 2 therapy for HIV positive individuals: Daily low doses enhance immune function without toxicity
    • Jacobson EL, Pilaro F, Smith KA: Rational interleukin 2 therapy for HIV positive individuals: Daily low doses enhance immune function without toxicity. Proc Natl Acad Sci USA 93:10405, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10405
    • Jacobson, E.L.1    Pilaro, F.2    Smith, K.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.