Synthetic cd4 Exocyclic Peptides Antagonize cd4 Holoreceptor Binding and T cell Activation

Nature Biotechnology

Volumn 14, Issue 4, 1996, Pages 472-475

  Zhang, Xin ^a   Piatier Tonneau, Dominique ^b   Auffray, Charles ^b   Murali, Ramachandran ^a   Mahapatra, Ajit ^a   Zhang, Fuqing ^a   Maier, Curtis C ^a   Saragovi, H ^c   Greene, Mark I ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CNRS   (France)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

CD4 and MHC II interaction; Complementarity determining region; Rational drug design

Indexed keywords

CD4 ANTIGEN; PEPTIDE; LYMPHOCYTE ANTIGEN RECEPTOR;

CELL ACTIVATION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANTIGEN BINDING; ARTICLE; BINDING COMPETITION; HUMAN; HUMAN CELL; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANTIGENS, CD4; BIOTECHNOLOGY; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LYMPHOCYTE ACTIVATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; T-LYMPHOCYTES;

EID: 0029670575     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt0496-472     Document Type: Article

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