Interaction between the antigen and antibody is controlled by the constant domains: Normal mode dynamics of the HEL-HyHEL-10 complex

Protein Science

Volumn 12, Issue 10, 2003, Pages 2125-2131

  Adachi, Masaaki ^a   Kurihara, Youji ^a   Nojima, Hiroyuki ^a   Takeda Shitaka, Mayuko ^a   Kamiya, Kenshu ^a   Umeyama, Hideaki ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Affinity; Constant domain; Immunoglobulin; Normal mode analysis; Protein interaction

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN LIGHT CHAIN; LYSOZYME; MONOCLONAL ANTIBODY; SOLVENT; WATER;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ARTICLE; ATOMIC PARTICLE; CALCULATION; COMPLEX FORMATION; DISSOCIATION; DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; VIBRATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIGEN-ANTIBODY REACTIONS; BINDING SITES, ANTIBODY; CHICKENS; COMPLEMENTARITY DETERMINING REGIONS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; EPITOPES; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; MODELS, MOLECULAR; MURAMIDASE; PROTEIN BINDING; PROTEIN CONFORMATION; WATER;

EID: 0141524063     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.03100803     Document Type: Article

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