CD4-imitating human antibodies in HIV infection and anti-idiotypic vaccination

Journal of Immunology

Volumn 156, Issue 2, 1996, Pages 826-833

  Deckert, Peter Markus ^a   Ballmaier, Mathias ^a   Lang, Sabine ^a   Deicher, Helmuth ^a   Schedel, Ingolf ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IDIOTYPIC ANTIBODY; MONOCLONAL ANTIBODY;

ANTIBODY RESPONSE; ARTICLE; BINDING COMPETITION; CLINICAL ARTICLE; CLINICAL TRIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; VACCINATION;

ADULT; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, CD4; CROSS REACTIONS; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOTHERAPY, ACTIVE; MALE; MICE; MIDDLE AGED; MOLECULAR MIMICRY; RABBITS; RECOMBINANT PROTEINS; VACCINATION;

EID: 0030058669     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Jerne, N K. 1984. Idiotypic networks and other preconceived ideas. Immunol. Rev 79:5.
2. Kennedy, J. R. 1990 AIDS - an autoimmune model Med Hypotheses 31 303.
3. Koprowski, H. 1985 Unconventional vaccines: immunization with anti-idiotype antibody against viral diseases. Cancer Res. 45 (Suppl):4689s.
4. Dalgleish, A. G , B J. Thomson, T. C. Chanh, M. Malkovsky, and R C. Kennedy. 1987. Neutralisation of HIV isolates by anti-idiotypic antibodies which mimic the T4 (CD4) epitope: a potential AIDS vaccine. Lancet 2(8567) 1047
5. Dreesman, G. R., and C Kennedy. 1985 Anti-idiotypic antibodies: implications of internal image-based vaccines for infectious diseases. J Infect Dis. 151:761
6. Dalgleish, A G., and R. C. Kennedy. 1988. Anti-idiotypic antibodies as immunogens: idiotype-based vaccines. Vaccine 6:215.
7. Sattentau, O J., J. Arthos, K. Deen, N. Hanna, P. C. L Beverly, R. Sweet, and A Truneh. 1989 Structural analysis of the human immunodeficiency virus-binding domain of CD4. J Exp. Med 170.1319.
8. Jameson, B. A., P E. Rao, L I. Kong, B. H. Hahn, G. M. Shaw, L. E. Hood, and S B. H. Kent 1988. Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein Science 240:1335
9. Peterson, A., and B. Seed. 1988. Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4. Cell 64:65.
10. Sattentau, Q J , and R. A Weiss. 1988. The CD4-antigen: physiological ligand and HIV receptor. Cell 52.631.
11. Wang, J. H., Y. W. Yan, T P. Garrett, J. H. Liu, D. W Rodgers, R. L. Garlick, G. E. Tarr, Y. Husain, E. L. Reinherz, and S. C. Harrison. 1990 Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature 348.411
12. Sattentau, Q. J., A G. Dalgleish, R. A Weiss, and P C. Beverley 1986. Epitopes of the CD4 antigen and HIV infection. Science 234:1120.
13. Bowman, M. R., K D. MacFerrin, S. L Schreiber, and S. J. Burakoff. 1990 Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and Class II major histocompatibility complex molecules. Proc. Natl. Acad. Sci USA 87:9052.
14. Healey, D G., L. Dianda, D Buck, K. Schroeder, A. Truneh, Q. J Sattentau, and P. C. Beverley. 1991. A highly selected panel of anti-CD4 antibodies fails to induce anti-idiotypic antisera mediating human immunodeficiency virus neutralization. Eur J. Immunol 21:1491.
15. Sutor, G C., U. Dreikhausen, U. Vaehning, E. Jurkiewicz, G. Hunsmann, K Lundin, and I. Schedel. 1992 Neutralization of HIV-1 by anti-idiotypes to monoclonal anti-CD4: potential for idiotype immunization against HIV. J Immunol. 149:1452.
16. Winkelmann, P., U. Dreikhausen, I. Schedel, J. Flik, and H. Deicher. 1989 T4a-"internal image" -bearing antibodies in sera of patients with HIV-1-infection. Int. Conf. AIDS 5:342 (abstr. no. T B.P 334).
17. Lundin, K., A Karlsson, A. Nygren, A Lofstrom, D. Gigliotti, and H. Wigzell 1988. Certain human gp120-HIV antibodies react with anti-CD4 antibodies. Scand J. Immunol 27:113.
18. Nygren, L K , P. Flodby, and H. Wigzell. 1988. HIV-seropositive sera contain antibodies mimicking CD4 molecules. In Human Retroviruses, Cancer and AIDS: Approaches to Prevention, and Therapy. D. Bolognes, ed Wiley-Liss. New York (Abstr. No. P116).
19. Guesdon, J. L., T Ternynck, and S. J. Avrameas. 1979. The use of avidin-biotin interaction in immunoenzymatic techniques. Histochem Cytochem. 27:1131.
20. Spearman, C. 1904. The proof and measurement of association between two things (classical article) Am J Psychol 11:441
21. Kantor, S., and W Winkelstein. Jr. 1970 Further observations on the nature of the index of classification accuracy - its relationship to Kendall's tau. Am. J Epidemiol 91:19.
22. Boettcher, H. F., and C. Posthoff. 1975. Die mathematische Behandlung der Rangkorrelation - eine vergleichende Betrachtung der Koeffizienten von Kendall und Spearman [Published in German, translated title: Mathematical treatment of rank correlation - a comparison of Spearman's and Kendall's coefficients]. Z. Psychol. Z. Angew. Psychol 183:201.
23. Wilks, D., L. C. Walker, J. A Habeshaw, M. Youle, B. Gazzard, and A. G. Dalgleish. 1990 Anti-CD4 autoantibodies and screening for anti-idiotypic antibodies to anti-CD4 monoclonal antibodies in HIV-seropositive people. AIDS 4:113.
24. Lundin, K., V. Holmberg, E. Sandstrom, and H. Wigzell. 1992. CD4-mimicking antibodies in HIV-positive and normal human sera J. Acquired Immune Defic Syndr. 5:658.
25. Attanasio, R., J S Allan, S. A. Anderson, T. C. Chanh, and R. C. Kennedy. 1991. Anti-idiotypic antibody response to monoclonal anti-CD4 preparations in non-human primate species. J. Immunol. 146:507.
26. Healey, D. G., L Dianda, and P. C. L. Beverley. 1992. A "network antigen" for human CD4: a murine monoclonal anti-idiotype to Leu-3a induces an anti-CD4 response in naive mice. J. Immunol. 148:821.
27. Putney, S. 1992 How antibodies block HIV infection: paths to an AIDS vaccine. Trends Biochem. Sci 17:191.
28. Wilks, D., L. C. Walker, J. A. Habeshaw, A. D. Webster, and A. G. Dalgleish. 1991. Antiidiotypic responses to immunization with anti-Leu 3a in human immunodeficiency virus-seropositive individuals J. Infect. Dis. 163:389.
29. Martinez-Mazar, O., E. Crabb, R. T. Mituyasu, J. L. Fahey, and J. V. Giorgi. 1987. Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B-lymphocyte activation and immaturity. J. Immunol. 138: 3720.
30. Mosmann, T. R. 1994. Cytokine patterns during the progression to AIDS. Science 265:193.
31. Berkower, I., D. Murphy, C. C. Smith, and G E. Smith. 1991. A predominant group-specific neutralizing epitope of human immunodeficiency virus type 1 maps to residues 342 to 511 of the envelope glycoprotein gp120. J. Virol. 65: 5983