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Biochemical Society Transactions

Volumn 30, Issue 4, 2002, Pages 487-490

Engineering therapeutic antibodies for improved function

(5) Presta, Leonard G a Shields, R L a Namenuk, A K a Hong, K a Meng, Y G a

a MERCK RESEARCH LABORATORIES (United States)

Author keywords

Antibody; Antibody dependent cellular cytotoxicity (ADCC); Fc receptor; Neonatal Fc receptor (FcRn)

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY; RECEPTOR SUBTYPE; RITUXIMAB; TRASTUZUMAB;

ANTIBODY AFFINITY; ANTIBODY ENGINEERING; BINDING SITE; CONFERENCE PAPER; CYTOTOXICITY TEST; DRUG EFFICACY; DRUG HALF LIFE; DRUG RECEPTOR BINDING; HUMAN; IN VITRO STUDY; MONONUCLEAR CELL; NATURAL KILLER CELL; NONHODGKIN LYMPHOMA; NONHUMAN; PEPTIDE MAPPING; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN FUNCTION; PROTEIN VARIANT; RECEPTOR AFFINITY; RECEPTOR BINDING;

ANTIBODIES, MONOCLONAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; B-LYMPHOCYTES; GENETIC ENGINEERING; HUMANS; IMMUNOGLOBULIN G; KILLER CELLS, NATURAL; RECEPTORS, IGG; RECOMBINANT FUSION PROTEINS;

EID: 0036670565 PISSN: 03005127 EISSN: None Source Type: Journal
DOI: 10.1042/BST0300487 Document Type: Conference Paper

Times cited : (62)

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