-
1
-
-
0033361906
-
Naturally occurring mutations of the luteinizing-hormone receptor: Lessons learned about reproductive physiology and G protein-coupled receptors
-
Latronico AC, Segaloff DL 1999 Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors. Am J Hum Genet 65:949-958
-
(1999)
Am J Hum Genet
, vol.65
, pp. 949-958
-
-
Latronico, A.C.1
Segaloff, D.L.2
-
2
-
-
0033711033
-
Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal function
-
Themmen APN, Huhtaniemi IT 2000 Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function. Endocr Rev 21:551-583
-
(2000)
Endocr Rev
, vol.21
, pp. 551-583
-
-
Themmen, A.P.N.1
Huhtaniemi, I.T.2
-
3
-
-
0036217072
-
The lutropin/choriogonadotropin receptor. A 2002 perspective
-
Ascoli M, Fanelli F, Segaloff DL 2002 The lutropin/choriogonadotropin receptor. A 2002 perspective. Endocr Rev 23:141-174
-
(2002)
Endocr Rev
, vol.23
, pp. 141-174
-
-
Ascoli, M.1
Fanelli, F.2
Segaloff, D.L.3
-
4
-
-
0033518280
-
Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor
-
Liu G, Duranteau L, Carel J-C, Monroe J, Doyle DA, Shenker A 1999 Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor. N Engl J Med 341:1731-1736
-
(1999)
N Engl J Med
, vol.341
, pp. 1731-1736
-
-
Liu, G.1
Duranteau, L.2
Carel, J.-C.3
Monroe, J.4
Doyle, D.A.5
Shenker, A.6
-
5
-
-
0036962992
-
Male LH-independent sexual precocity in a 3.5-year-old boy caused by a somatic activating mutation of the LH receptor in a Leydig cell tumor
-
Richter-Unruh A, Wessels HT, Menken U, Bergmann M, Schittmann-Ohters K, Schaper J, Tapeser S, Hauffa BP 2002 Male LH-independent sexual precocity in a 3.5-year-old boy caused by a somatic activating mutation of the LH receptor in a Leydig cell tumor. J Clin Endocrinol Metab 87:1052-1056
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1052-1056
-
-
Richter-Unruh, A.1
Wessels, H.T.2
Menken, U.3
Bergmann, M.4
Schittmann-Ohters, K.5
Schaper, J.6
Tapeser, S.7
Hauffa, B.P.8
-
6
-
-
0019364734
-
Characterization of several clonal lines of cultured Leydig tumor cells: Gonadotropin receptors and steroidogenic responses
-
Ascoli M 1981 Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses. Endocrinology 108:88-95
-
(1981)
Endocrinology
, vol.108
, pp. 88-95
-
-
Ascoli, M.1
-
7
-
-
0000311735
-
Immortalized Leydig cell lines as models for studying Leydig cell physiology
-
Payne AH, Hardy MP, Russell LD, eds. Vienna, IL: Cache River Press
-
Hoelscher SR, Ascoli M 1996 Immortalized Leydig cell lines as models for studying Leydig cell physiology. In: Payne AH, Hardy MP, Russell LD, eds. The Leydig cell. Vienna, IL: Cache River Press; 523-534
-
(1996)
The Leydig Cell
, pp. 523-534
-
-
Hoelscher, S.R.1
Ascoli, M.2
-
8
-
-
0242298720
-
The lutropin/choriogonadotropin receptor (LHR)-induced phosphorylation of the extracellular signal regulated kinases (ERKs) in Leydig cells is mediated by a protein kinase A-dependent activation of Ras
-
Hirakawa T, Ascoli M 2003 The lutropin/choriogonadotropin receptor (LHR)-induced phosphorylation of the extracellular signal regulated kinases (ERKs) in Leydig cells is mediated by a protein kinase A-dependent activation of Ras. Mol Endocrinol 17:2189-2200
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2189-2200
-
-
Hirakawa, T.1
Ascoli, M.2
-
9
-
-
0036171565
-
MA-10 cells transfected with the human lutropin/choriogonadotropin receptor (hLHR). A novel experimental paradigm to study the functional properties of the hLHR
-
Hirakawa T, Galet C, Ascoli M 2002 MA-10 cells transfected with the human lutropin/choriogonadotropin receptor (hLHR). A novel experimental paradigm to study the functional properties of the hLHR. Endocrinology 143:1026-1035
-
(2002)
Endocrinology
, vol.143
, pp. 1026-1035
-
-
Hirakawa, T.1
Galet, C.2
Ascoli, M.3
-
10
-
-
0041920692
-
A constitutively active somatic mutation of the human lutropin receptor found in Leydig cell tumors activates the same families of G proteins as germ line mutations associated with Leydig cell hyperplasia
-
Hirakawa T, Ascoli M 2003 A constitutively active somatic mutation of the human lutropin receptor found in Leydig cell tumors activates the same families of G proteins as germ line mutations associated with Leydig cell hyperplasia. Endocrinology 144:3872-3878
-
(2003)
Endocrinology
, vol.144
, pp. 3872-3878
-
-
Hirakawa, T.1
Ascoli, M.2
-
11
-
-
4644293240
-
Extracellular signal-regulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin
-
Martinelle N, Holst M, Soder O, Svechnikov K 2004 Extracellular signal-regulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin. Endocrinology 145:4629-4634
-
(2004)
Endocrinology
, vol.145
, pp. 4629-4634
-
-
Martinelle, N.1
Holst, M.2
Soder, O.3
Svechnikov, K.4
-
12
-
-
0037509990
-
Focal adhesion kinase: The first ten years
-
Parsons TJ 2003 Focal adhesion kinase: the first ten years. J Cell Sci 116:1409-1416
-
(2003)
J Cell Sci
, vol.116
, pp. 1409-1416
-
-
Parsons, T.J.1
-
14
-
-
3142521875
-
Control of motile and invasive cell phenotypes by focal adhesion kinase
-
Schlaepfer DD, Mitra SK, Ilic D 2004 Control of motile and invasive cell phenotypes by focal adhesion kinase. Biochim Biophys Acta 1692:77-102
-
(2004)
Biochim Biophys Acta
, vol.1692
, pp. 77-102
-
-
Schlaepfer, D.D.1
Mitra, S.K.2
Ilic, D.3
-
15
-
-
21744435478
-
The role of focal-adhesion kinase in cancer - A new therapeutic opportunity
-
McLean GW, Carragher NO, Avizienyte E, Evans J, Brunton VG, Frame MC 2005 The role of focal-adhesion kinase in cancer - a new therapeutic opportunity. Nat Rev Cancer 5:505-515
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 505-515
-
-
McLean, G.W.1
Carragher, N.O.2
Avizienyte, E.3
Evans, J.4
Brunton, V.G.5
Frame, M.C.6
-
16
-
-
0030029143
-
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor
-
Hanke JH, Gardner JP, Dow RL, Changelian PS, Brissette WH, Weringer EJ, Pollok BA, Connelly PA 1996 Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. J Biol Chem 271:695-701
-
(1996)
J Biol Chem
, vol.271
, pp. 695-701
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
Changelian, P.S.4
Brissette, W.H.5
Weringer, E.J.6
Pollok, B.A.7
Connelly, P.A.8
-
17
-
-
17644402459
-
Transduction of receptor signals by β-arrestins
-
Lefkowitz RJ, Shenoy SK 2005 Transduction of receptor signals by β-arrestins. Science 308:512-517
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
18
-
-
7944226933
-
Not so strange bedfellows: G-protein-coupled receptors and Src family kinases
-
Luttrell DK, Luttrell LM 2004 Not so strange bedfellows: G-protein-coupled receptors and Src family kinases. Oncogene 23:7969-7978
-
(2004)
Oncogene
, vol.23
, pp. 7969-7978
-
-
Luttrell, D.K.1
Luttrell, L.M.2
-
19
-
-
0032938716
-
Regulation of tyrosine kinase cascades by G-protein-coupled receptors
-
Luttrell LM, Daaka Y, Lefkowitz RJ 1999 Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol 11:177-183
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 177-183
-
-
Luttrell, L.M.1
Daaka, Y.2
Lefkowitz, R.J.3
-
20
-
-
0034693806
-
Selected glimpses into the activation and function of Src kinase
-
Bjorge JD, Jakymiw A, Fujita DJ 2000 Selected glimpses into the activation and function of Src kinase. Oncogene 19:5620-5635
-
(2000)
Oncogene
, vol.19
, pp. 5620-5635
-
-
Bjorge, J.D.1
Jakymiw, A.2
Fujita, D.J.3
-
22
-
-
17444374230
-
Src kinase regulation by phosphorylation and dephosphorylation
-
Roskoski Jr R 2005 Src kinase regulation by phosphorylation and dephosphorylation. Biochem Biophys Res Commun 331:1-14
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 1-14
-
-
Roskoski Jr., R.1
-
23
-
-
0034268796
-
Src tyrosine kinase is a novel direct effect of G proteins
-
Ma Y-C, Huang J, Ali S, Lowry W, Huang X-Y 2000 Src tyrosine kinase is a novel direct effect of G proteins. Cell 102:635-646
-
(2000)
Cell
, vol.102
, pp. 635-646
-
-
Ma, Y.-C.1
Huang, J.2
Ali, S.3
Lowry, W.4
Huang, X.-Y.5
-
24
-
-
0034616883
-
Apoptotic signaling through the β-adrenergic receptor. A new Gs effector pathway
-
Gu C, Ma Y-C, Benjamin J, Littman D, Chao MV, Huang X-Y 2000 Apoptotic signaling through the β-adrenergic receptor. A new Gs effector pathway. J Biol Chem 275:20726-20733
-
(2000)
J Biol Chem
, vol.275
, pp. 20726-20733
-
-
Gu, C.1
Ma, Y.-C.2
Benjamin, J.3
Littman, D.4
Chao, M.V.5
Huang, X.-Y.6
-
25
-
-
0024353098
-
Mutation of amino acids in pp60s-src that are phosphorylated by protein kinases C and A
-
Yaciuk P, Choi J-K, Shalloway D 1989 Mutation of amino acids in pp60s-src that are phosphorylated by protein kinases C and A. Mol Cell Biol 9:2453-2463
-
(1989)
Mol Cell Biol
, vol.9
, pp. 2453-2463
-
-
Yaciuk, P.1
Choi, J.-K.2
Shalloway, D.3
-
26
-
-
0036161707
-
PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1
-
Schmitt JM, Stork PJS 2002 PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1. Mol Cell 9:85-94
-
(2002)
Mol Cell
, vol.9
, pp. 85-94
-
-
Schmitt, J.M.1
Stork, P.J.S.2
-
27
-
-
12344333887
-
PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells
-
Obara Y, Labudda K, Dillon TJ, Stork PJS 2004 PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells. J Cell Sci 117:6085-6094
-
(2004)
J Cell Sci
, vol.117
, pp. 6085-6094
-
-
Obara, Y.1
Labudda, K.2
Dillon, T.J.3
Stork, P.J.S.4
-
29
-
-
0041315574
-
cAMP analog mapping of Epac1 and cAMP kinase: Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension
-
Christensen AE, Selheim F, de Rooij J, Dremier S, Schwede F, Dao KK, Martinez A, Maenhaut C, Bos JL, Genieser H-G, Doskeland SO 2003 cAMP analog mapping of Epac1 and cAMP kinase: discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension. J Biol Chem 278:35394-35402
-
(2003)
J Biol Chem
, vol.278
, pp. 35394-35402
-
-
Christensen, A.E.1
Selheim, F.2
De Rooij, J.3
Dremier, S.4
Schwede, F.5
Dao, K.K.6
Martinez, A.7
Maenhaut, C.8
Bos, J.L.9
Genieser, H.-G.10
Doskeland, S.O.11
-
30
-
-
85006314494
-
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
-
Enserink JM, Christensen AE, de Rooij J, van Triest M, Schwede F, Genieser HG, Doskeland SO, Blank JL, Bos JL 2002 A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nat Cell Biol 4:901-906
-
(2002)
Nat Cell Biol
, vol.4
, pp. 901-906
-
-
Enserink, J.M.1
Christensen, A.E.2
De Rooij, J.3
Van Triest, M.4
Schwede, F.5
Genieser, H.G.6
Doskeland, S.O.7
Blank, J.L.8
Bos, J.L.9
-
31
-
-
0035040924
-
Endothelin system: The double-edged sword in health and disease
-
Kedzierski RM, Yanagisawa M 2001 Endothelin system: the double-edged sword in health and disease. Annu Rev Pharmacol Toxicol 41:851-876
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 851-876
-
-
Kedzierski, R.M.1
Yanagisawa, M.2
-
32
-
-
0024533488
-
The inositol phosphate/diacylglycerol pathway in MA-10 Leydig tumor cells. Activation by arginine vasopressin and lack of effect of epidermal growth factor and human choriogonadotropin
-
Ascoli M, Pignataro OP, Segaloff DL 1989 The inositol phosphate/diacylglycerol pathway in MA-10 Leydig tumor cells. Activation by arginine vasopressin and lack of effect of epidermal growth factor and human choriogonadotropin. J Biol Chem 264:6674-6681
-
(1989)
J Biol Chem
, vol.264
, pp. 6674-6681
-
-
Ascoli, M.1
Pignataro, O.P.2
Segaloff, D.L.3
-
33
-
-
0345529916
-
Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: Role of Src and GIT
-
Shikata Y, Birukov KG, Birukova AA, Verin A, Garcia JGN 2003 Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT. FASEB J 17:2240-2249
-
(2003)
FASEB J
, vol.17
, pp. 2240-2249
-
-
Shikata, Y.1
Birukov, K.G.2
Birukova, A.A.3
Verin, A.4
Garcia, J.G.N.5
-
34
-
-
7944237784
-
The interplay between Src family kinases and receptor tyrosine kinases
-
Bromann PA, Korkaya H, Courtneidge SA 2004 The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 23:7957-7968
-
(2004)
Oncogene
, vol.23
, pp. 7957-7968
-
-
Bromann, P.A.1
Korkaya, H.2
Courtneidge, S.A.3
-
35
-
-
0035918269
-
c-Src tyrosine kinase binds the β 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization
-
Fan G-f, Shumay E, Malbon CC, Wang H-y 2001 c-Src tyrosine kinase binds the β 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization. J Biol Chem 276:13240-13247
-
(2001)
J Biol Chem
, vol.276
, pp. 13240-13247
-
-
Fan, G.-F.1
Shumay, E.2
Malbon, C.C.3
Wang, H.-Y.4
-
36
-
-
0023755783
-
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity
-
Gould KL, Hunter T 1988 Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity. Mol Cell Biol 8:3345-3356
-
(1988)
Mol Cell Biol
, vol.8
, pp. 3345-3356
-
-
Gould, K.L.1
Hunter, T.2
-
37
-
-
0036720834
-
Src tyrosine kinase-induced loss of luteinizing hormone responsiveness is via a Ras-dependent, phosphatidylinositol-3-kinase independent pathway
-
Taylor CC 2002 Src tyrosine kinase-induced loss of luteinizing hormone responsiveness is via a Ras-dependent, phosphatidylinositol-3-kinase independent pathway. Biol Reprod 67:789-794
-
(2002)
Biol Reprod
, vol.67
, pp. 789-794
-
-
Taylor, C.C.1
-
38
-
-
0030476607
-
Src tyrosine kinase activity is related to luteinizing hormone responsiveness: Genetic manipulations using mouse MA10 Leydig cells
-
Taylor C, Limback D, Terranova P 1996 Src tyrosine kinase activity is related to luteinizing hormone responsiveness: genetic manipulations using mouse MA10 Leydig cells. Endocrinology 137:5735-5738
-
(1996)
Endocrinology
, vol.137
, pp. 5735-5738
-
-
Taylor, C.1
Limback, D.2
Terranova, P.3
-
39
-
-
0032211806
-
Fyn, a Src family tyrosine kinase
-
Resh MD 1998 Fyn, a Src family tyrosine kinase. Int J Biochem Cell Biol 30:1159-1162
-
(1998)
Int J Biochem Cell Biol
, vol.30
, pp. 1159-1162
-
-
Resh, M.D.1
-
40
-
-
0035957958
-
Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains
-
Espanel X, Sudol M 2001 Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains. J Biol Chem 276:14514-14523
-
(2001)
J Biol Chem
, vol.276
, pp. 14514-14523
-
-
Espanel, X.1
Sudol, M.2
-
41
-
-
0031435817
-
Modulation of the arrestin-clathrin interaction in cells
-
Krupnick JG, Santini F, Gagnon AW, Keen JH, Benovic JL 1997 Modulation of the arrestin-clathrin interaction in cells. J Biol Chem 272:32507-32512
-
(1997)
J Biol Chem
, vol.272
, pp. 32507-32512
-
-
Krupnick, J.G.1
Santini, F.2
Gagnon, A.W.3
Keen, J.H.4
Benovic, J.L.5
-
42
-
-
0037016682
-
The association of arrestin-3 with the human lutropin/choriogonadotropin receptor depends mostly on receptor activation rather than on receptor phosphorylation
-
Min L, Galet C, Ascoli M 2002 The association of arrestin-3 with the human lutropin/choriogonadotropin receptor depends mostly on receptor activation rather than on receptor phosphorylation. J Biol Chem 277:702-710
-
(2002)
J Biol Chem
, vol.277
, pp. 702-710
-
-
Min, L.1
Galet, C.2
Ascoli, M.3
-
44
-
-
0035735452
-
A new phospholipase-C-calcium signaling pathway mediated by cyclic AMP and a Rap GTPase
-
Schmid M, Evellin S, Weernink PAO, vom Dorp F, Rehmann H, Lomasney JW, Jakobs KH 2001 A new phospholipase-C-calcium signaling pathway mediated by cyclic AMP and a Rap GTPase. Nat Cell Biol 3:1020-1024
-
(2001)
Nat Cell Biol
, vol.3
, pp. 1020-1024
-
-
Schmid, M.1
Evellin, S.2
Weernink, P.A.O.3
Vom Dorp, F.4
Rehmann, H.5
Lomasney, J.W.6
Jakobs, K.H.7
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