-
1
-
-
9444286388
-
Expression of normal and mutant huntingtin in the developing brain
-
P.G. Bhide, M. Day, E. Sapp, C. Schwarz, A. Sheth, J. Kim, A.B. Young, J. Penney, J. Golden, N. Aronin, and M. DiFiglia Expression of normal and mutant huntingtin in the developing brain J. Neurosci. 16 1996 5523 5535
-
(1996)
J. Neurosci.
, vol.16
, pp. 5523-5535
-
-
Bhide, P.G.1
Day, M.2
Sapp, E.3
Schwarz, C.4
Sheth, A.5
Kim, J.6
Young, A.B.7
Penney, J.8
Golden, J.9
Aronin, N.10
Difiglia, M.11
-
2
-
-
0032833981
-
Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin
-
J.M. Boutell, P. Thomas, J.W. Neal, V.J. Weston, J. Duce, P.S. Harper, and A.L. Jones Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin Hum. Mol. Genet. 8 1999 1647 1655
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1647-1655
-
-
Boutell, J.M.1
Thomas, P.2
Neal, J.W.3
Weston, V.J.4
Duce, J.5
Harper, P.S.6
Jones, A.L.7
-
3
-
-
7144253143
-
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture
-
J.K. Cooper, G. Schilling, M.F. Peters, W.J. Herring, A.H. Sharp, Z. Kaminsky, J. Masone, F.A. Khan, M. Delanoy, D.R. Borchelt, V.L. Dawson, T.M. Dawson, and C.A. Ross Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture Hum. Mol. Genet. 7 1998 783 790
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 783-790
-
-
Cooper, J.K.1
Schilling, G.2
Peters, M.F.3
Herring, W.J.4
Sharp, A.H.5
Kaminsky, Z.6
Masone, J.7
Khan, F.A.8
Delanoy, M.9
Borchelt, D.R.10
Dawson, V.L.11
Dawson, T.M.12
Ross, C.A.13
-
4
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
S.W. Davies, M. Turmaine, B.A. Cozens, M. DiFiglia, A.H. Sharp, C.A. Ross, E. Scherzinger, E.E. Wanker, L. Mangiarini, and G.P. Bates Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation Cell 90 1997 537 548
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
Difiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
5
-
-
0029816724
-
Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation
-
K.E. De Rooij, J.C. Dorsman, M.A. Smoor, J.T. Den Dunnen, and G.J. Van Ommen Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation Hum. Mol. Genet. 5 1996 1093 1099
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1093-1099
-
-
De Rooij, K.E.1
Dorsman, J.C.2
Smoor, M.A.3
Den Dunnen, J.T.4
Van Ommen, G.J.5
-
6
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
M. DiFiglia, E. Sapp, K. Chase, C. Schwarz, A. Meloni, C. Young, E. Martin, J.-P. Vonsattel, R. Carraway, S.A. Reeves, F.M. Boyce, and N. Aronin Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons Neuron 14 1995 1075 1081
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
Martin, E.7
Vonsattel, J.-P.8
Carraway, R.9
Reeves, S.A.10
Boyce, F.M.11
Aronin, N.12
-
7
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
M. DiFiglia, E. Sapp, K. Chase, S.W. Davies, G.P. Bates, J.-P. Vonsattel, and N. Aronin Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 277 1997 1990 1993
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.-P.6
Aronin, N.7
-
8
-
-
0033614774
-
Analysis of the subcellular localization of huntingtin with a set of rabbit polyclonal antibodies in cultured mammalian cells of neuronal origin: Comparison with the distribution of huntingtin in Huntington's disease autopsy brain
-
J.C. Dorsman, M.A. Smoor, M.L. Maat-Schieman, M. Bout, S. Siesling, S.G. van Duinen, J.J. Verschuuren, J.T. den Dunnen, R.A. Roos, and G.J. van Ommen Analysis of the subcellular localization of huntingtin with a set of rabbit polyclonal antibodies in cultured mammalian cells of neuronal origin: comparison with the distribution of huntingtin in Huntington's disease autopsy brain Philos. Trans. R. Soc. Lond. B Biol. Sci. 354 1386 1999 1061 1067
-
(1999)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.354
, Issue.1386
, pp. 1061-1067
-
-
Dorsman, J.C.1
Smoor, M.A.2
Maat-Schieman, M.L.3
Bout, M.4
Siesling, S.5
Van Duinen, S.G.6
Verschuuren, J.J.7
Den Dunnen, J.T.8
Roos, R.A.9
Van Ommen, G.J.10
-
9
-
-
2642646258
-
Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues
-
I. Dragatsis, A. Efstratiadis, and S. Zeitlin Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues Development 125 1998 1529 1539
-
(1998)
Development
, vol.125
, pp. 1529-1539
-
-
Dragatsis, I.1
Efstratiadis, A.2
Zeitlin, S.3
-
10
-
-
0029082383
-
Inactivation of the mouse Huntington's disease gene homolog Hdh
-
M.P. Duyao, A.B. Auerbach, A. Ryan, F. Persichetti, G.T. Barnes, S.M. McNeil, P. Ge, J.-P. Vonsattel, J.F. Guesella, and A.L. Joyner Inactivation of the mouse Huntington's disease gene homolog Hdh Science 269 1995 407 410
-
(1995)
Science
, vol.269
, pp. 407-410
-
-
Duyao, M.P.1
Auerbach, A.B.2
Ryan, A.3
Persichetti, F.4
Barnes, G.T.5
McNeil, S.M.6
Ge, P.7
Vonsattel, J.-P.8
Guesella, J.F.9
Joyner, A.L.10
-
11
-
-
0033119123
-
Nuclear and neuropil aggregates in Huntington's disease: Relationship to neuropathology
-
C.A. Gutekunst, S.H. Li, H. Yi, J.S. Mulroy, S. Kuemmerle, R. Jones, D. Rye, R.J. Ferrante, S.M. Hersch, and X.J. Li Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology J. Neurosci. 19 1999 2522 2534
-
(1999)
J. Neurosci.
, vol.19
, pp. 2522-2534
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Mulroy, J.S.4
Kuemmerle, S.5
Jones, R.6
Rye, D.7
Ferrante, R.J.8
Hersch, S.M.9
Li, X.J.10
-
12
-
-
0032101287
-
The influence of huntingtin protein size on nuclear localization and cellular toxicity
-
A.S. Hackam, R. Singaraja, C.L. Wellington, M. Metzler, K. McCutcheon, T. Zhang, M. Kalchman, and M.R. Hayden The influence of huntingtin protein size on nuclear localization and cellular toxicity J. Cell. Biol. 141 1998 1097 1105
-
(1998)
J. Cell. Biol.
, vol.141
, pp. 1097-1105
-
-
Hackam, A.S.1
Singaraja, R.2
Wellington, C.L.3
Metzler, M.4
McCutcheon, K.5
Zhang, T.6
Kalchman, M.7
Hayden, M.R.8
-
13
-
-
0344961865
-
The use of transgenic and knock-in mice to study Huntington's disease
-
M.A. Hickey, and M.F. Chesselet The use of transgenic and knock-in mice to study Huntington's disease Cytogenet. Genome Res. 100 1-4 2003 276 286
-
(2003)
Cytogenet. Genome Res.
, vol.100
, Issue.1-4
, pp. 276-286
-
-
Hickey, M.A.1
Chesselet, M.F.2
-
14
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group, 1993. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72, 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
15
-
-
0033737382
-
Subcellular localization of presenilins during mouse preimplantation development
-
S.J. Jeong, H.S. Kim, K.A. Chang, D.H. Geum, C.H. Park, J.H. Seo, J.C. Rah, J.H. Lee, S.H. Choi, S.G. Lee, K. Kim, and Y.H. Suh Subcellular localization of presenilins during mouse preimplantation development FASEB J. 14 2000 2171 2176
-
(2000)
FASEB J.
, vol.14
, pp. 2171-2176
-
-
Jeong, S.J.1
Kim, H.S.2
Chang, K.A.3
Geum, D.H.4
Park, C.H.5
Seo, J.H.6
Rah, J.C.7
Lee, J.H.8
Choi, S.H.9
Lee, S.G.10
Kim, K.11
Suh, Y.H.12
-
16
-
-
0032587646
-
Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin
-
M. Kim, J. Velier, K. Chase, G. Laforet, M.A. Kalchman, M.R. Hayden, L. Won, A. Heller, N. Aronin, and M. DiFiglia Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin Neuroscience 89 1999 1159 1167
-
(1999)
Neuroscience
, vol.89
, pp. 1159-1167
-
-
Kim, M.1
Velier, J.2
Chase, K.3
Laforet, G.4
Kalchman, M.A.5
Hayden, M.R.6
Won, L.7
Heller, A.8
Aronin, N.9
Difiglia, M.10
-
17
-
-
18544368523
-
Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription
-
K.B. Kegel, A.R. Meloni, Y. Yi, Y.J. Kim, E. Doyle, B.G. Cuiffo, E. Sapp, Y. Wang, Z.H. Qin, J.D. Chen, J.R. Nevins, N. Aronin, and M. DiFiglia Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription J. Biol. Chem. 277 2002 7466 7476
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7466-7476
-
-
Kegel, K.B.1
Meloni, A.R.2
Yi, Y.3
Kim, Y.J.4
Doyle, E.5
Cuiffo, B.G.6
Sapp, E.7
Wang, Y.8
Qin, Z.H.9
Chen, J.D.10
Nevins, J.R.11
Aronin, N.12
Difiglia, M.13
-
18
-
-
0034703874
-
Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis
-
S.H. Li, S. Lam, A.L. Cheng, and X.J. Li Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis Hum. Mol. Genet. 9 2000 2859 2867
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2859-2867
-
-
Li, S.H.1
Lam, S.2
Cheng, A.L.3
Li, X.J.4
-
19
-
-
0036671821
-
Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions
-
A. Lunkes, K.S. Lindenberg, L. Ben-Haiem, C. Weber, D. Devys, G.B. Landwehrmeyer, J.L. Mandel, and Y. Trottier Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions Mol. Cell. 10 2002 259 269
-
(2002)
Mol. Cell.
, vol.10
, pp. 259-269
-
-
Lunkes, A.1
Lindenberg, K.S.2
Ben-Haiem, L.3
Weber, C.4
Devys, D.5
Landwehrmeyer, G.B.6
Mandel, J.L.7
Trottier, Y.8
-
20
-
-
0033025958
-
Distribution of inclusions in neuronal nuclei and dystrophic neurites in Huntington disease brain
-
M.L. Maat-Schieman, J.C. Dorsman, M.A. Smoor, S. Siesling, S.G. Van Duinen, J.J. Verschuuren, J.T. den Dunnen, G.J. Van Ommen, and R.A. Roos Distribution of inclusions in neuronal nuclei and dystrophic neurites in Huntington disease brain J. Neuropathol. Exp. Neurol. 58 1999 129 137
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 129-137
-
-
Maat-Schieman, M.L.1
Dorsman, J.C.2
Smoor, M.A.3
Siesling, S.4
Van Duinen, S.G.5
Verschuuren, J.J.6
Den Dunnen, J.T.7
Van Ommen, G.J.8
Roos, R.A.9
-
21
-
-
0036974461
-
Nuclear localization of N-terminal mutant huntingtin is cell cycle dependent
-
E. Martin-Aparicio, J. Avila, and J.J. Lucas Nuclear localization of N-terminal mutant huntingtin is cell cycle dependent Eur. J. Neurosci. 16 2002 355 359
-
(2002)
Eur. J. Neurosci.
, vol.16
, pp. 355-359
-
-
Martin-Aparicio, E.1
Avila, J.2
Lucas, J.J.3
-
22
-
-
0029055717
-
Targeted disruption of the Huntington's disease gene results in embryoniclethality and behavioral and morphological changes in heterozygotes
-
J. Nasir, S.B. Floresco, J.R. O'Kusky, V.M. Diewert, J.M. Richman, J. Zeisler, A. Borowski, J.D. Marth, A.G. Phillips, and M.R. Hayden Targeted disruption of the Huntington's disease gene results in embryoniclethality and behavioral and morphological changes in heterozygotes Cell 81 1995 811 823
-
(1995)
Cell
, vol.81
, pp. 811-823
-
-
Nasir, J.1
Floresco, S.B.2
O'Kusky, J.R.3
Diewert, V.M.4
Richman, J.M.5
Zeisler, J.6
Borowski, A.7
Marth, J.D.8
Phillips, A.G.9
Hayden, M.R.10
-
23
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
F.C. Nucifora Jr., M. Sasaki, M.F. Peters, H. Huang, J.K. Cooper, M. Yamada, H. Takahashi, S. Tsuji, J. Troncoso, V.L. Dawson, T.M. Dawson, and C.A. Ross Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity Science 291 2001 2423 2428
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora Jr., F.C.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
Yamada, M.6
Takahashi, H.7
Tsuji, S.8
Troncoso, J.9
Dawson, V.L.10
Dawson, T.M.11
Ross, C.A.12
-
24
-
-
0032847708
-
Nuclear targeting of mutant Huntingtin increases toxicity
-
M.F. Peters, F.C. Nucifora Jr., I. Kushi, H.C. Seaman, J.K. Cooper, W.J. Herring, V.L. Dawson, T.M. Dawson, and C.A. Ross Nuclear targeting of mutant Huntingtin increases toxicity Mol. Cell. Neurosci. 14 1999 121 128
-
(1999)
Mol. Cell. Neurosci.
, vol.14
, pp. 121-128
-
-
Peters, M.F.1
Nucifora Jr., F.C.2
Kushi, I.3
Seaman, H.C.4
Cooper, J.K.5
Herring, W.J.6
Dawson, V.L.7
Dawson, T.M.8
Ross, C.A.9
-
25
-
-
0034792802
-
Wild-type huntingtin up-regulates BDNF transcription in Huntington's disease
-
C.E. Reilly Wild-type huntingtin up-regulates BDNF transcription in Huntington's disease J. Neurol. 248 2001 920 922
-
(2001)
J. Neurol.
, vol.248
, pp. 920-922
-
-
Reilly, C.E.1
-
26
-
-
0742304252
-
Wild-type huntingtin plays a role in brain development and neuronal survival
-
A. Reiner, I. Dragatsis, S. Zeitlin, and D. Goldowitz Wild-type huntingtin plays a role in brain development and neuronal survival Mol. Neurobiol. 28 2003 259 276
-
(2003)
Mol. Neurobiol.
, vol.28
, pp. 259-276
-
-
Reiner, A.1
Dragatsis, I.2
Zeitlin, S.3
Goldowitz, D.4
-
27
-
-
0030771894
-
Huntingtin localization in brains of normal and Huntington's disease patients
-
E. Sapp, C. Schwarz, K. Chase, P.G. Bhide, A.B. Young, J. Penney, J.-P. Vonsattel, N. Aronin, and M. DiFiglia Huntingtin localization in brains of normal and Huntington's disease patients Ann. Neurol. 42 1997 604 612
-
(1997)
Ann. Neurol.
, vol.42
, pp. 604-612
-
-
Sapp, E.1
Schwarz, C.2
Chase, K.3
Bhide, P.G.4
Young, A.B.5
Penney, J.6
Vonsattel, J.-P.7
Aronin, N.8
Difiglia, M.9
-
28
-
-
0033054555
-
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin
-
G. Schilling, M.W. Becher, A.H. Sharp, H.A. Jinnah, K. Duan, J.A. Kotzuk, H.H. Slunt, T. Ratovitski, J.K. Cooper, N.A. Jenkins, N.G. Copeland, D.L. Price, C.A. Ross, and D.R. Borchelt Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin Hum. Mol. Genet. 8 1999 397 407
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 397-407
-
-
Schilling, G.1
Becher, M.W.2
Sharp, A.H.3
Jinnah, H.A.4
Duan, K.5
Kotzuk, J.A.6
Slunt, H.H.7
Ratovitski, T.8
Cooper, J.K.9
Jenkins, N.A.10
Copeland, N.G.11
Price, D.L.12
Ross, C.A.13
Borchelt, D.R.14
-
29
-
-
4344636957
-
Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice
-
G. Schilling, A.V. Savonenko, A. Klevytska, J.L. Morton, S.M. Tucker, M. Poirier, A. Gale, N. Chan, V. Gonzales, H.H. Slunt, M.L. Coonfield, N.A. Jenkins, N.G. Copeland, C.A. Ross, and D.R. Borchelt Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice Hum. Mol. Genet. 13 2004 1599 1610
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1599-1610
-
-
Schilling, G.1
Savonenko, A.V.2
Klevytska, A.3
Morton, J.L.4
Tucker, S.M.5
Poirier, M.6
Gale, A.7
Chan, N.8
Gonzales, V.9
Slunt, H.H.10
Coonfield, M.L.11
Jenkins, N.A.12
Copeland, N.G.13
Ross, C.A.14
Borchelt, D.R.15
-
30
-
-
0033037919
-
Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein
-
K.A. Sieradzan, A.O. Mechan, L. Jones, E.E. Wanker, N. Nukina, and D.M. Mann Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein Exp. Neurol. 156 1 1999 92 99
-
(1999)
Exp. Neurol.
, vol.156
, Issue.1
, pp. 92-99
-
-
Sieradzan, K.A.1
Mechan, A.O.2
Jones, L.3
Wanker, E.E.4
Nukina, N.5
Mann, D.M.6
-
31
-
-
0029034511
-
Widespread expression of Huntington's disease gene IT15 protein product
-
A.H. Sharp, S.J. Love, G. Schilling, S.H. Li, X.J. Li, L. Bao, M.V. Wagster, J.A. Kotzuk, J.P. Steiner, and A. Lo Widespread expression of Huntington's disease gene IT15 protein product Neuron 14 1995 1065 1074
-
(1995)
Neuron
, vol.14
, pp. 1065-1074
-
-
Sharp, A.H.1
Love, S.J.2
Schilling, G.3
Li, S.H.4
Li, X.J.5
Bao, L.6
Wagster, M.V.7
Kotzuk, J.A.8
Steiner, J.P.9
Lo, A.10
-
32
-
-
12944263711
-
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
-
J.S. Steffan, A. Kazantsev, O. Spasic-Boskovic, M. Greenwald, Y.Z. Zhu, H. Gohler, E.E. Wanker, G.P. Bates, D.E. Housman, and L.M. Thompson The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription Proc. Natl. Acad. Sci. U.S.A. 97 2000 6763 6768
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 6763-6768
-
-
Steffan, J.S.1
Kazantsev, A.2
Spasic-Boskovic, O.3
Greenwald, M.4
Zhu, Y.Z.5
Gohler, H.6
Wanker, E.E.7
Bates, G.P.8
Housman, D.E.9
Thompson, L.M.10
-
33
-
-
0141742228
-
The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor
-
H. Takano, and J.F. Gusella The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor BMC Neurosci. 3 2002 15
-
(2002)
BMC Neurosci.
, vol.3
, pp. 15
-
-
Takano, H.1
Gusella, J.F.2
-
34
-
-
0042355277
-
An expanded role for wild-type huntingtin in neuronal transcription
-
L.M. Thompson An expanded role for wild-type huntingtin in neuronal transcription Nat. Genet. 35 2003 13 14
-
(2003)
Nat. Genet.
, vol.35
, pp. 13-14
-
-
Thompson, L.M.1
-
35
-
-
0034163497
-
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice
-
V.C. Wheeler, J.K. White, C.A. Gutekunst, V. Vrbanac, M. Weaver, X.J. Li, S.H. Li, H. Yi, J.-P. Vonsattel, J.F. Gusella, S. Hersch, W. Auerbach, A.L. Joyner, and M.E. MacDonald Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice Hum. Mol. Genet. 9 2000 503 513
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 503-513
-
-
Wheeler, V.C.1
White, J.K.2
Gutekunst, C.A.3
Vrbanac, V.4
Weaver, M.5
Li, X.J.6
Li, S.H.7
Yi, H.8
Vonsattel, J.-P.9
Gusella, J.F.10
Hersch, S.11
Auerbach, W.12
Joyner, A.L.13
MacDonald, M.E.14
-
36
-
-
0030613177
-
Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion
-
J.K. White, W. Auerbach, M.P. Duyao, J.-P. Vonsattel, J.E. Gusella, A.L. Joyner, and M.E. MacDonald Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion Nat. Genet. 17 1997 404 410
-
(1997)
Nat. Genet.
, vol.17
, pp. 404-410
-
-
White, J.K.1
Auerbach, W.2
Duyao, M.P.3
Vonsattel, J.-P.4
Gusella, J.E.5
Joyner, A.L.6
MacDonald, M.E.7
-
37
-
-
84993912315
-
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
-
S. Zeitlin, J.P. Liu, D.L. Chapman, V.E. Papaioannou, and A. Efstratiadis Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue Nat. Genet. 11 1995 155 163
-
(1995)
Nat. Genet.
, vol.11
, pp. 155-163
-
-
Zeitlin, S.1
Liu, J.P.2
Chapman, D.L.3
Papaioannou, V.E.4
Efstratiadis, A.5
-
38
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
C. Zuccato, M. Tartari, A. Crotti, D. Goffredo, M. Valenza, L. Conti, T. Cataudella, B.R. Leavitt, M.R. Hayden, T. Timmusk, D. Rigamonti, and E. Cattaneo Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes Nat. Genet. 35 2003 76 83
-
(2003)
Nat. Genet.
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
Rigamonti, D.11
Cattaneo, E.12
-
39
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
C. Zuccato, A. Ciammola, D. Rigamonti, B.R. Leavitt, D. Goffredo, L. Conti, M.E. MacDonald, R.M. Friedlander, V. Silani, M.R. Hayden, T. Timmusk, S. Sipione, and E. Cattaneo Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease Science 293 2001 493 498
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
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